Identification of small molecule antagonists of the human mas-related gene-X1 receptor

Analytical Biochemistry

Volumn 351, Issue 1, 2006, Pages 50-61

  Kunapuli, Priya ^a   Lee, Seungtaek ^a   Zheng, Wei ^b   Alberts, Melissa ^a   Kornienko, Oleg ^a   Mull, Rebecca ^a   Kreamer, Anthony ^a   Hwang, Jong Ik ^c   Simon, Melvin I ^c   Strulovici, Berta ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Azabicyclo octanes; GFP; GPCRs; High throughput screening; MRG X1; Receptor trafficking; Reporter gene assay

Indexed keywords

CYTOLOGY; MOLECULES; NEURONS; SENSORY PERCEPTION;

AZABICYCLO-OCTANES; GPCRS; HIGH THROUGHPUT SCREENING; MRG-X1; RECEPTOR TRAFFICKING; REPORTER GENE ASSAYS;

GENES;

ANALGESIC AGENT; BETA LACTAMASE; CALCIUM ION; G PROTEIN COUPLED RECEPTOR; MAS RELATED GENE X1 RECEPTOR; MAS RELATED GENE X1 RECEPTOR ANTAGONIST; PEPTIDE BAM15; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; FEMALE; GENE EXPRESSION; IC 50; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; RADIOASSAY; REPORTER GENE; STRUCTURE ACTIVITY RELATION; VALIDATION PROCESS;

ANIMALIA;

EID: 33644966300     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2006.01.014     Document Type: Article

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