메뉴 건너뛰기




Volumn 9, Issue 1, 2014, Pages

Chitosan-graft-polyethylenimine/DNA nanoparticles as novel non-viral gene delivery vectors targeting osteoarthritis

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; BIOLOGICAL TRANSPORT; CELL SURVIVAL; CHITOSAN; CHONDROCYTES; DNA; GENE EXPRESSION; GENES, REPORTER; INTRACELLULAR SPACE; NANOPARTICLES; OSTEOARTHRITIS; POLYETHYLENEIMINE; RABBITS; SYNOVIAL MEMBRANE; TRANSFECTION;

EID: 84894231121     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0084703     Document Type: Article
Times cited : (111)

References (43)
  • 1
    • 79959906654 scopus 로고    scopus 로고
    • Targeted delivery of non-viral vectors to cartilage in vivo using a chondrocyte-homing peptide identified by phage display
    • doi:10.1016/j.biomaterials.2011.05.017. PMID: 21624651
    • Pi Y, Zhang X, Shi J, Zhu J, Chen W, et al. (2011) Targeted delivery of non-viral vectors to cartilage in vivo using a chondrocyte-homing peptide identified by phage display. Biomaterials 32: 6324-6332. doi:10.1016/j. biomaterials.2011.05.017. PMID: 21624651.
    • (2011) Biomaterials , vol.32 , pp. 6324-6332
    • Pi, Y.1    Zhang, X.2    Shi, J.3    Zhu, J.4    Chen, W.5
  • 2
    • 30944445959 scopus 로고    scopus 로고
    • Direct chitosan-mediated gene delivery to the rabbit knee joints in vitro and in vivo
    • doi: 10.1016/j.bbrc.2005.12.171. PMID: 16413501
    • Zhang X, Yu C, Xushi, Zhang C, Tang T, et al. (2006) Direct chitosan-mediated gene delivery to the rabbit knee joints in vitro and in vivo. Biochem Biophys Res Commun 341: 202-208. doi: 10.1016/j.bbrc.2005.12.171. PMID: 16413501.
    • (2006) Biochem Biophys Res Commun , vol.341 , pp. 202-208
    • Zhang, X.1    Yu, C.2    Xushi3    Zhang, C.4    Tang, T.5
  • 4
    • 45849151689 scopus 로고    scopus 로고
    • Efficient gene delivery using chitosan-polyethylenimine hybrid systems
    • doi: 10.1088/1748-6041/3/2/025013. PMID: 18477817
    • Jiang HL, Kim TH, Kim YK, Park IY, Cho MH, et al. (2008) Efficient gene delivery using chitosan-polyethylenimine hybrid systems. Biomed Mater 3: 025013. doi: 10.1088/1748-6041/3/2/025013. PMID: 18477817.
    • (2008) Biomed Mater , vol.3 , pp. 025013
    • Jiang, H.L.1    Kim, T.H.2    Kim, Y.K.3    Park, I.Y.4    Cho, M.H.5
  • 5
    • 84863914822 scopus 로고    scopus 로고
    • Polymers for gene delivery: Current status and future perspectives
    • doi:10.2174/187221512801327389. PMID: 22670610
    • Rekha MR, Sharma CP (2012) Polymers for gene delivery: current status and future perspectives. Recent Pat DNA Gene Seq 6: 98-107. doi:10.2174/ 187221512801327389. PMID: 22670610.
    • (2012) Recent Pat DNA Gene Seq , vol.6 , pp. 98-107
    • Rekha, M.R.1    Sharma, C.P.2
  • 6
    • 79960022298 scopus 로고    scopus 로고
    • Polycation-based gene therapy: Current knowledge and new perspectives
    • doi: 10.2174/156652311796150408. PMID: 21453278
    • Tiera MJ, Shi Q, Winnik FM, Fernandes JC (2011) Polycation-based gene therapy: current knowledge and new perspectives. Curr Gene Ther 11: 288-306. doi: 10.2174/156652311796150408. PMID: 21453278.
    • (2011) Curr Gene Ther , vol.11 , pp. 288-306
    • Tiera, M.J.1    Shi, Q.2    Winnik, F.M.3    Fernandes, J.C.4
  • 7
    • 44749083254 scopus 로고    scopus 로고
    • Arginine-chitosan/DNA self-assemble nanoparticles for gene delivery: In vitro characteristics and transfection efficiency
    • doi:10.1016/j.ijpharm.2008.03.037. PMID: 18479851
    • Gao Y, Xu Z, Chen S, Gu W, Chen L, et al. (2008) Arginine-chitosan/DNA self-assemble nanoparticles for gene delivery: In vitro characteristics and transfection efficiency. Int J Pharm 359: 241-246. doi:10.1016/j.ijpharm.2008. 03.037. PMID: 18479851.
    • (2008) Int J Pharm , vol.359 , pp. 241-246
    • Gao, Y.1    Xu, Z.2    Chen, S.3    Gu, W.4    Chen, L.5
  • 8
    • 77649191250 scopus 로고    scopus 로고
    • Gene-carried chitosan-linked-PEI induced high gene transfection efficiency with low toxicity and significant tumor-suppressive activity
    • doi: 10.1016/j.ijpharm.2009.12.033. PMID: 20035848
    • Gao JQ, Zhao QQ, Lv TF, Shuai WP, Zhou J, et al. (2010) Gene-carried chitosan-linked-PEI induced high gene transfection efficiency with low toxicity and significant tumor-suppressive activity. Int J Pharm 387: 286-294. doi: 10.1016/j.ijpharm.2009.12.033. PMID: 20035848.
    • (2010) Int J Pharm , vol.387 , pp. 286-294
    • Gao, J.Q.1    Zhao, Q.Q.2    Lv, T.F.3    Shuai, W.P.4    Zhou, J.5
  • 9
    • 84860400943 scopus 로고    scopus 로고
    • Linear polyethylenimine-graft-chitosan copolymers as efficient DNA/siRNA delivery vectors in vitro and in vivo
    • doi: 10.1016/j.nano.2011.06.022. PMID: 21756861
    • Tripathi SK, Goyal R, Kumar P, Gupta KC (2012) Linear polyethylenimine-graft-chitosan copolymers as efficient DNA/siRNA delivery vectors in vitro and in vivo. Nanomedicine 8: 337-345. doi: 10.1016/j.nano.2011. 06.022. PMID: 21756861.
    • (2012) Nanomedicine , vol.8 , pp. 337-345
    • Tripathi, S.K.1    Goyal, R.2    Kumar, P.3    Gupta, K.C.4
  • 10
    • 0037472115 scopus 로고    scopus 로고
    • Chitosan-based gastrointestinal delivery systems
    • DOI 10.1016/S0168-3659(03)00126-3
    • Hejazi R, Amiji M (2003) Chitosan-based gastrointestinal delivery systems. J Control Release 89: 151-165. doi:10.1016/S0168-3659(03)00126-3. PMID: 12711440. (Pubitemid 36507012)
    • (2003) Journal of Controlled Release , vol.89 , Issue.2 , pp. 151-165
    • Hejazi, R.1    Amiji, M.2
  • 11
    • 26844514770 scopus 로고    scopus 로고
    • Chitosan-alginate as scaffolding material for cartilage tissue engineering
    • DOI 10.1002/jbm.a.30449
    • Li Z, Zhang M (2005) Chitosan-alginate as scaffolding material for cartilage tissue engineering. J Biomed Mater Res A 75: 485-493. doi:10.1002/jbm.a.30449. PMID: 16092113. (Pubitemid 41463919)
    • (2005) Journal of Biomedical Materials Research - Part A , vol.75 , Issue.2 , pp. 485-493
    • Li, Z.1    Zhang, M.2
  • 12
    • 75149133614 scopus 로고    scopus 로고
    • Chitosan-based formulations for delivery of DNA and siRNA
    • doi:10.1016/j.addr.2009.08.004. PMID: 19796660
    • Mao S, Sun W, Kissel T (2010) Chitosan-based formulations for delivery of DNA and siRNA. Adv Drug Deliv Rev 62: 12-27. doi:10.1016/j.addr.2009.08.004. PMID: 19796660.
    • (2010) Adv Drug Deliv Rev , vol.62 , pp. 12-27
    • Mao, S.1    Sun, W.2    Kissel, T.3
  • 13
    • 21744437897 scopus 로고    scopus 로고
    • Synergistic effect of poly(ethylenimine) on the transfection efficiency of galactosylated chitosan/DNA complexes
    • DOI 10.1016/j.jconrel.2005.03.024, PII S0168365905001331
    • Kim TH, Kim SI, Akaike T, Cho CS (2005) Synergistic effect of poly(ethylenimine) on the transfection efficiency of galactosylated chitosan/DNA complexes. J Control Release 105: 354-366. doi:10.1016/j.jconrel.2005.03.024. PMID: 15949861. (Pubitemid 40941999)
    • (2005) Journal of Controlled Release , vol.105 , Issue.3 , pp. 354-366
    • Tae, H.K.1    Su, I.K.2    Akaike, T.3    Chong, S.C.4
  • 15
    • 39449125413 scopus 로고    scopus 로고
    • Combination of poly(ethylenimine) and chitosan induces high gene transfection efficiency and low cytotoxicity
    • DOI 10.1263/jbb.105.65, PII S1389172308700276
    • Zhao QQ, Chen JL, Han M, Liang WQ, Tabata Y, et al. (2008) Combination of poly(ethylenimine) and chitosan induces high gene transfection efficiency and low cytotoxicity. J Biosci Bioeng 105: 65-68. doi:10.1263/jbb.105.65. PMID: 18295723. (Pubitemid 351273667)
    • (2008) Journal of Bioscience and Bioengineering , vol.105 , Issue.1 , pp. 65-68
    • Zhao, Q.-Q.1    Chen, J.-L.2    Han, M.3    Liang, W.-Q.4    Tabata, Y.5    Gao, J.-Q.6
  • 16
    • 80054688920 scopus 로고    scopus 로고
    • Novel hyaluronic acid-chitosan nanoparticles as non-viral gene delivery vectors targeting osteoarthritis
    • doi:10.1016/j.ijpharm.2011.08.046. PMID: 21911044
    • Lu HD, Zhao HQ, Wang K, Lv LL (2011) Novel hyaluronic acid-chitosan nanoparticles as non-viral gene delivery vectors targeting osteoarthritis. Int J Pharm 420: 358-365. doi:10.1016/j.ijpharm.2011.08.046. PMID: 21911044.
    • (2011) Int J Pharm , vol.420 , pp. 358-365
    • Lu, H.D.1    Zhao, H.Q.2    Wang, K.3    Lv, L.L.4
  • 17
    • 31544461289 scopus 로고    scopus 로고
    • PEI-g-chitosan, a novel gene delivery system with transfection efficiency comparable to polyethylenimine in vitro and after liver administration in vivo
    • DOI 10.1021/bc0501597
    • Wong K, Sun G, Zhang X, Dai H, Liu Y, et al. (2006) PEI-g-chitosan, a novel gene delivery system with transfection efficiency comparable to polyethylenimine in vitro and after liver administration in vivo. Bioconjug Chem 17: 152-158. doi:10.1021/bc0501597. PMID: 16417264. (Pubitemid 43157597)
    • (2006) Bioconjugate Chemistry , vol.17 , Issue.1 , pp. 152-158
    • Wong, K.1    Sun, G.2    Zhang, X.3    Dai, H.4    Liu, Y.5    He, C.6    Leong, K.W.7
  • 18
    • 33745077164 scopus 로고    scopus 로고
    • High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation
    • DOI 10.1016/j.biomaterials.2006.04.029, PII S0142961206003838
    • Lavertu M, Méthot S, Tran-Khanh N, Buschmann MD (2006) High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation. Biomaterials 27: 4815-4824. doi:10.1016/j.biomaterials.2006.04.029. PMID: 16725196. (Pubitemid 43880352)
    • (2006) Biomaterials , vol.27 , Issue.27 , pp. 4815-4824
    • Lavertu, M.1    Methot, S.2    Tran-Khanh, N.3    Buschmann, M.D.4
  • 19
    • 65249099011 scopus 로고    scopus 로고
    • N/P ratio significantly influences the transfection efficiency and cytotoxicity of a polyethylenimine/chitosan/DNA complex
    • doi:10.1248/bpb.32.706. PMID: 19336909
    • Zhao QQ, Chen JL, Lv TF, He CX, Tang GP, et al. (2009) N/P ratio significantly influences the transfection efficiency and cytotoxicity of a polyethylenimine/chitosan/DNA complex. Biol Pharm Bull 32: 706-710. doi:10.1248/bpb.32.706. PMID: 19336909.
    • (2009) Biol Pharm Bull , vol.32 , pp. 706-710
    • Zhao, Q.Q.1    Chen, J.L.2    Lv, T.F.3    He, C.X.4    Tang, G.P.5
  • 20
    • 27944503506 scopus 로고    scopus 로고
    • Dilution of reporter gene with stuffer DNA does not alter the transfection efficiency of polyethylenimines
    • DOI 10.1002/jgm.805
    • Kichler A, Leborgne C, Danos O (2005) Dilution of reporter gene with stuffer DNA does not alter the transfection efficiency of polyethylenimines. J Gene Med 7: 1459-1467. doi:10.1002/jgm.805. PMID: 16041686. (Pubitemid 41672404)
    • (2005) Journal of Gene Medicine , vol.7 , Issue.11 , pp. 1459-1467
    • Kichler, A.1    Leborgne, C.2    Danos, O.3
  • 22
    • 67650608146 scopus 로고    scopus 로고
    • Chitosan-graft-polyethylenimine for Akt1 siRNA delivery to lung cancer cells
    • doi:10.1016/j.ijpharm.2009.05.046. PMID: 19501140
    • Jere D, Jiang HL, Kim YK, Arote R, Choi YJ, et al. (2009) Chitosan-graft-polyethylenimine for Akt1 siRNA delivery to lung cancer cells. Int J Pharm. 378: 194-200. doi:10.1016/j.ijpharm.2009.05.046. PMID: 19501140.
    • (2009) Int J Pharm , vol.378 , pp. 194-200
    • Jere, D.1    Jiang, H.L.2    Kim, Y.K.3    Arote, R.4    Choi, Y.J.5
  • 23
    • 84867887400 scopus 로고    scopus 로고
    • Synovial inflammation, immune cells and their cytokines in osteoarthritis: A review
    • doi: 10.1016/j.joca.2012.08.027. PMID: 22960092
    • de Lange-Brokaar BJ, Ioan-Facsinay A, van Osch GJ, Zuurmond AM, Schoones J, et al. (2012) Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review. Osteoarthritis Cartilage 20: 1484-1499. doi: 10.1016/j.joca.2012.08.027. PMID: 22960092.
    • (2012) Osteoarthritis Cartilage , vol.20 , pp. 1484-1499
    • De Lange-Brokaar, B.J.1    Ioan-Facsinay, A.2    Van Osch, G.J.3    Zuurmond, A.M.4    Schoones, J.5
  • 24
    • 84871921917 scopus 로고    scopus 로고
    • Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)
    • doi:10.1016/j.joca.2012.11.012. PMID: 23194896
    • Berenbaum F (2013) Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!). Osteoarthritis Cartilage 21: 16-21. doi:10.1016/j.joca.2012.11.012. PMID: 23194896.
    • (2013) Osteoarthritis Cartilage , vol.21 , pp. 16-21
    • Berenbaum, F.1
  • 25
    • 84867332559 scopus 로고    scopus 로고
    • Intra-articular lentivirus-mediated insertion of the fat-1 gene ameliorates osteoarthritis
    • doi:10.1016/j.mehy.2012.07.035. PMID: 22939867
    • Huang MJ, Wang L, Zheng XC, Zhang ZM, Yan B, et al. (2012) Intra-articular lentivirus-mediated insertion of the fat-1 gene ameliorates osteoarthritis. Med Hypotheses 79: 614-616. doi:10.1016/j.mehy.2012.07.035. PMID: 22939867.
    • (2012) Med Hypotheses , vol.79 , pp. 614-616
    • Huang, M.J.1    Wang, L.2    Zheng, X.C.3    Zhang, Z.M.4    Yan, B.5
  • 26
    • 76049120294 scopus 로고    scopus 로고
    • MDR1a/1b gene silencing enhances drug sensitivity in rat fibroblast-like synoviocytes
    • doi: 10.1002/jgm.1378. PMID:19950109
    • Honjo K, Takahashi KA, Mazda O, Kishida T, Shinya M, et al. (2010) MDR1a/1b gene silencing enhances drug sensitivity in rat fibroblast-like synoviocytes. J Gene Med 12: 219-227. doi: 10.1002/jgm.1378. PMID:19950109.
    • (2010) J Gene Med , vol.12 , pp. 219-227
    • Honjo, K.1    Takahashi, K.A.2    Mazda, O.3    Kishida, T.4    Shinya, M.5
  • 27
    • 84855827685 scopus 로고    scopus 로고
    • Linear PEI nanoparticles: Efficient pDNA/siRNA carriers in vitro and in vivo
    • doi:10.1016/j.nano.2011.06.001. PMID:21703995
    • Goyal R, Tripathi SK, Tyagi S, Sharma A, Ram KR, et al. (2012) Linear PEI nanoparticles: efficient pDNA/siRNA carriers in vitro and in vivo. Nanomedicine 8: 167-175. doi:10.1016/j.nano.2011.06.001. PMID:21703995.
    • (2012) Nanomedicine , vol.8 , pp. 167-175
    • Goyal, R.1    Tripathi, S.K.2    Tyagi, S.3    Sharma, A.4    Ram, K.R.5
  • 28
    • 13644264961 scopus 로고    scopus 로고
    • The role of dextran conjugation in transfection mediated by dextran-grafted polyethylenimine
    • DOI 10.1002/jgm.572
    • Tseng WC, Tang CH, Fang TY (2004) The role of dextran conjugation in transfection mediated by dextran-grafted polyethylenimine. J Gene Med 6: 895-905. doi:10.1002/jgm.572. PMID:15293348. (Pubitemid 40228105)
    • (2004) Journal of Gene Medicine , vol.6 , Issue.8 , pp. 895-905
    • Tseng, W.-C.1    Tang, C.-H.2    Fang, T.-Y.3
  • 29
    • 58049118322 scopus 로고    scopus 로고
    • Effects and mechanisms of total glucosides of paeony on synoviocytes activities in rat collagen-induced arthritis
    • doi: 10.1016/j.jep.2008.09.028. PMID:18977427
    • Chang Y, Wei W, Zhang L, Xu HM (2009) Effects and mechanisms of total glucosides of paeony on synoviocytes activities in rat collagen-induced arthritis. J Ethnopharmacol 121: 43-48. doi: 10.1016/j.jep.2008.09.028. PMID:18977427.
    • (2009) J Ethnopharmacol , vol.121 , pp. 43-48
    • Chang, Y.1    Wei, W.2    Zhang, L.3    Xu, H.M.4
  • 30
    • 0036737813 scopus 로고    scopus 로고
    • Star-shaped poly(ethylene glycol)-block-polyethylenimine copolymers enhance DNA condensation of low molecular weight polyethylenimines
    • doi: 10.1021/bm025539z. PMID: 12217037
    • Petersen H, Kunath K, Martin AL, Stolnik S, Roberts CJ, et al. (2002) Star-shaped poly(ethylene glycol)-block-polyethylenimine copolymers enhance DNA condensation of low molecular weight polyethylenimines. Biomacromolecules 3: 926-936. doi: 10.1021/bm025539z. PMID: 12217037.
    • (2002) Biomacromolecules , vol.3 , pp. 926-936
    • Petersen, H.1    Kunath, K.2    Martin, A.L.3    Stolnik, S.4    Roberts, C.J.5
  • 31
    • 0034000909 scopus 로고    scopus 로고
    • A simple preparation of half N-acetylated chitosan highly soluble in water and aqueous organic solvents
    • DOI 10.1016/S0008-6215(99)00263-3, PII S0008621599002633
    • Kubota N, Tatsumoto N, Sano T, Toya K (2000) A simple preparation of half N-acetylated chitosan highly soluble in water and aqueous organic solvents. Carbohydr Res 324: 268-274. doi:10.1016/S0008-6215(99)00263-3. PMID: 10744335. (Pubitemid 30114453)
    • (2000) Carbohydrate Research , vol.324 , Issue.4 , pp. 268-274
    • Kubota, N.1    Tatsumoto, N.2    Sano, T.3    Toya, K.4
  • 32
    • 0037437033 scopus 로고    scopus 로고
    • Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: Comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine
    • DOI 10.1016/S0168-3659(03)00076-2
    • Kunath K, von Harpe A, Fischer D, Petersen H, Bickel U, et al. (2003) Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine. J Control Release 89: 113-125. doi:10.1016/S0168-3659(03)00076-2. PMID: 12695067. (Pubitemid 36412116)
    • (2003) Journal of Controlled Release , vol.89 , Issue.1 , pp. 113-125
    • Kunath, K.1    Von Harpe, A.2    Fischer, D.3    Petersen, H.4    Bickel, U.5    Voigt, K.6    Kissel, T.7
  • 33
    • 0035850217 scopus 로고    scopus 로고
    • DNA transfection using linear poly(ethylenimine) prepared by controlled acid hydrolysis of poly(2-ethyl-2-oxazoline)
    • DOI 10.1016/S0168-3659(01)00310-8, PII S0168365901003108
    • Jeong JH, Song SH, Lim DW, Lee H, Park TG (2001) DNA transfection using linear poly(ethylenimine) prepared by controlled acid hydrolysis of poly(2-ethyl-2-oxazoline). J Control Release 73: 391-399. doi:10.1016/S0168- 3659(01)00310-8. PMID: 11516514. (Pubitemid 32539265)
    • (2001) Journal of Controlled Release , vol.73 , Issue.2-3 , pp. 391-399
    • Jeong, J.H.1    Song, S.H.2    Lim, D.W.3    Lee, H.4    Park, T.G.5
  • 34
    • 77954694217 scopus 로고    scopus 로고
    • Cationic polymer optimization for efficient gene delivery
    • doi:10.2174/138955710791185109. PMID: 20408796
    • Sun X, Zhang N (2010) Cationic polymer optimization for efficient gene delivery. Mini Rev Med Chem 10: 108-125. doi:10.2174/138955710791185109. PMID: 20408796.
    • (2010) Mini Rev Med Chem , vol.10 , pp. 108-125
    • Sun, X.1    Zhang, N.2
  • 35
    • 0035980982 scopus 로고    scopus 로고
    • Design and gene delivery activity of modified polyethylenimines
    • doi:10.1016/S0169-409X(01)00202-2. PMID: 11744176
    • Kircheis R, Wightman L, Wagner E (2001) Design and gene delivery activity of modified polyethylenimines. Adv Drug Deliv Rev 53: 341-358. doi:10.1016/S0169-409X(01)00202-2. PMID: 11744176.
    • (2001) Adv Drug Deliv Rev , vol.53 , pp. 341-358
    • Kircheis, R.1    Wightman, L.2    Wagner, E.3
  • 36
    • 77953624672 scopus 로고    scopus 로고
    • Efficient gene transfection by histidine-modified chitosan through enhancement of endosomal escape
    • doi:10.1021/bc1000609. PMID: 20499901
    • Chang KL, Higuchi Y, Kawakami S, Yamashita F, Hashida M (2010) Efficient gene transfection by histidine-modified chitosan through enhancement of endosomal escape. Bioconjug Chem 21: 1087-1095. doi:10.1021/bc1000609. PMID: 20499901.
    • (2010) Bioconjug Chem , vol.21 , pp. 1087-1095
    • Chang, K.L.1    Higuchi, Y.2    Kawakami, S.3    Yamashita, F.4    Hashida, M.5
  • 37
    • 52049088251 scopus 로고    scopus 로고
    • Enhanced gene delivery using disulfide-crosslinked low molecular weight polyethylenimine with listeriolysin o-polyethylenimine disulfide conjugate
    • doi:10.1016/j.jconrel.2008.07.007. PMID: 18692533
    • Choi S, Lee KD (2008) Enhanced gene delivery using disulfide-crosslinked low molecular weight polyethylenimine with listeriolysin o-polyethylenimine disulfide conjugate. J Control Release 131: 70-76. doi:10.1016/j.jconrel.2008. 07.007. PMID: 18692533.
    • (2008) J Control Release , vol.131 , pp. 70-76
    • Choi, S.1    Lee, K.D.2
  • 38
    • 75549084093 scopus 로고    scopus 로고
    • Comparison on in vitro characterization of fucospheres and chitosan microspheres encapsulated plasmid DNA (pGM-CSF): Formulation design and release characteristics
    • doi:10.1208/s12249-009-9324-0. PMID: 19859814
    • Sezer AD, Akbuǧa J (2009) Comparison on in vitro characterization of fucospheres and chitosan microspheres encapsulated plasmid DNA (pGM-CSF): formulation design and release characteristics. AAPS PharmSciTech 10: 1193-1199. doi:10.1208/s12249-009-9324-0. PMID: 19859814.
    • (2009) AAPS PharmSciTech , vol.10 , pp. 1193-1199
    • Sezer, A.D.1    Akbuǧa, J.2
  • 39
    • 0034786764 scopus 로고    scopus 로고
    • Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo
    • DOI 10.1038/sj.gt.3301492
    • Köping-Höggård M, Tubulekas I, Guan H, Edwards K, Nilsson M, et al. (2001) Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo. Gene Ther 8: 1108-1121. doi:10.1038/sj.gt.3301492. PMID: 11526458. (Pubitemid 32962708)
    • (2001) Gene Therapy , vol.8 , Issue.14 , pp. 1108-1121
    • Koping-Hoggard, M.1    Tubulekas, I.2    Guan, H.3    Edwards, K.4    Nilsson, M.5    Varum, K.M.6    Artursson, P.7
  • 40
    • 0242322948 scopus 로고    scopus 로고
    • Relationship between the physical shape and the efficiency of oligomeric chitosan as a gene delivery system in vitro and in vivo
    • DOI 10.1002/jgm.327
    • Köping-Höggård M, Mel'nikova YS, Vårum KM, Lindman B, Artursson P (2003) Relationship between the physical shape and the efficiency of oligomeric chitosan as a gene delivery system in vitro and in vivo. J Gene Med 5: 130-141. doi: 10.1002/jgm.327. PMID: 12539151. (Pubitemid 40309690)
    • (2003) Journal of Gene Medicine , vol.5 , Issue.2 , pp. 130-141
    • Koping-Hoggard, M.1    Mel'nikova, Y.S.2    Varum, K.M.3    Lindman, B.4    Artursson, P.5
  • 41
    • 62749135925 scopus 로고    scopus 로고
    • Chitosan N-betainates/DNA self-assembly nanoparticles for gene delivery: In vitro uptake and transfection efficiency
    • doi: 10.1016/j.ijpharm.2008.12.012. PMID: 19135139
    • Gao Y, Zhang Z, Chen L, Gu W, Li Y (2009) Chitosan N-betainates/DNA self-assembly nanoparticles for gene delivery: in vitro uptake and transfection efficiency. Int J Pharm 371: 156-162. doi: 10.1016/j.ijpharm.2008.12.012. PMID: 19135139.
    • (2009) Int J Pharm , vol.371 , pp. 156-162
    • Gao, Y.1    Zhang, Z.2    Chen, L.3    Gu, W.4    Li, Y.5
  • 42
    • 33644630054 scopus 로고    scopus 로고
    • Intracellular uptake and release of poly(ethyleneimine)-co-poly(methyl methacrylate) nanoparticle/pDNA complexes for gene delivery
    • doi:10.1016/j.ijpharm.2005.12.035. PMID: 16442245
    • Feng M, Lee D, Li P (2006) Intracellular uptake and release of poly(ethyleneimine)-co-poly(methyl methacrylate) nanoparticle/pDNA complexes for gene delivery. Int J Pharm 311: 209-214. doi:10.1016/j.ijpharm.2005.12.035. PMID: 16442245.
    • (2006) Int J Pharm , vol.311 , pp. 209-214
    • Feng, M.1    Lee, D.2    Li, P.3
  • 43
    • 33645474488 scopus 로고    scopus 로고
    • Lactosylated chitosan for DNA delivery into hepatocytes: The effect of lactosylation on the physicochemical properties and intracellular trafficking of pDNA/chitosan complexes
    • doi:10.1021/bc050228h. PMID: 16536460
    • Hashimoto M, Morimoto M, Saimoto H, Shigemasa Y, Sato T (2006) Lactosylated chitosan for DNA delivery into hepatocytes: the effect of lactosylation on the physicochemical properties and intracellular trafficking of pDNA/chitosan complexes. Bioconjug Chem 17: 309-316. doi:10.1021/bc050228h. PMID: 16536460.
    • (2006) Bioconjug Chem , vol.17 , pp. 309-316
    • Hashimoto, M.1    Morimoto, M.2    Saimoto, H.3    Shigemasa, Y.4    Sato, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.