-
1
-
-
0034909663
-
Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium Wilfordii Hook F
-
B.J. Chen Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium wilfordii Hook F Leuk Lymphoma 42 2001 253 265 (Pubitemid 32725582)
-
(2001)
Leukemia and Lymphoma
, vol.42
, Issue.3
, pp. 253-265
-
-
Chen, B.J.1
-
2
-
-
79952106497
-
Triptolide and its expanding multiple pharmacological functions
-
Q. Liu Triptolide and its expanding multiple pharmacological functions Int Immunopharmacol 11 2011 377 383
-
(2011)
Int Immunopharmacol
, vol.11
, pp. 377-383
-
-
Liu, Q.1
-
3
-
-
78650418550
-
The safety and effectiveness of a chloroform/methanol extract of Tripterygium wilfordii Hook F (T2) plus methotrexate in treating rheumatoid arthritis
-
W. Zhang, Q. Shi, L.D. Zhao, Y. Li, F.L. Tang, and F.C. Zhang et al. The safety and effectiveness of a chloroform/methanol extract of Tripterygium wilfordii Hook F (T2) plus methotrexate in treating rheumatoid arthritis J Clin Rheumatol 16 2010 375 378
-
(2010)
J Clin Rheumatol
, vol.16
, pp. 375-378
-
-
Zhang, W.1
Shi, Q.2
Zhao, L.D.3
Li, Y.4
Tang, F.L.5
Zhang, F.C.6
-
4
-
-
33847278423
-
Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)
-
DOI 10.1016/j.phytochem.2006.11.029, PII S0031942206007370
-
A.M. Brinker, J. Ma, P.E. Lipsky, and I. Raskin Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae) Phytochemistry 68 2007 732 766 (Pubitemid 46330437)
-
(2007)
Phytochemistry
, vol.68
, Issue.6
, pp. 732-766
-
-
Brinker, A.M.1
Ma, J.2
Lipsky, P.E.3
Raskin, I.4
-
5
-
-
84863263731
-
Triptolide attenuate the oxidative stress induced by LPS/D-GalN in mice
-
Y. Lu, X. Bao, T. Sun, J. Xu, W. Zheng, and P. Shen Triptolide attenuate the oxidative stress induced by LPS/D-GalN in mice J Cell Biochem 113 2012 1022 1033
-
(2012)
J Cell Biochem
, vol.113
, pp. 1022-1033
-
-
Lu, Y.1
Bao, X.2
Sun, T.3
Xu, J.4
Zheng, W.5
Shen, P.6
-
6
-
-
79952489486
-
Triptolide alleviates hepatic ischemia/reperfusion injury by attenuating oxidative stress and inhibiting NF-kappaB activity in mice
-
C. Wu, P. Wang, J. Rao, Z. Wang, C. Zhang, and L. Lu et al. Triptolide alleviates hepatic ischemia/reperfusion injury by attenuating oxidative stress and inhibiting NF-kappaB activity in mice J Surg Res 166 2011 e205 e213
-
(2011)
J Surg Res
, vol.166
-
-
Wu, C.1
Wang, P.2
Rao, J.3
Wang, Z.4
Zhang, C.5
Lu, L.6
-
7
-
-
36649020474
-
Triptolide inhibits NF-kappaB activation and reduces injury of donor lung induced by ischemia/reperfusion
-
J.K. He, S.D. Yu, H.J. Zhu, J.C. Wu, and Z.H. Qin Triptolide inhibits NF-kappaB activation and reduces injury of donor lung induced by ischemia/reperfusion Acta Pharmacol Sin 28 2007 1919 1923
-
(2007)
Acta Pharmacol Sin
, vol.28
, pp. 1919-1923
-
-
He, J.K.1
Yu, S.D.2
Zhu, H.J.3
Wu, J.C.4
Qin, Z.H.5
-
8
-
-
80054908941
-
Inhibition of mitochondrial respiratory chain is involved in triptolide-induced liver injury
-
Q. Fu, X. Huang, B. Shu, M. Xue, P. Zhang, and T. Wang et al. Inhibition of mitochondrial respiratory chain is involved in triptolide-induced liver injury Fitoterapia 82 2011 1241 1248
-
(2011)
Fitoterapia
, vol.82
, pp. 1241-1248
-
-
Fu, Q.1
Huang, X.2
Shu, B.3
Xue, M.4
Zhang, P.5
Wang, T.6
-
9
-
-
0342804486
-
Posttesticular antifertility action of triptolide in the male rat: Evidence for severe impairment of cauda epididymal sperm ultrastructure
-
A.P. Hikim, Y.H. Lue, C. Wang, V. Reutrakul, R. Sangsuwan, and R.S. Swerdloff Posttesticular antifertility action of triptolide in the male rat: evidence for severe impairment of cauda epididymal sperm ultrastructure J Androl 21 2000 431 437 (Pubitemid 30252515)
-
(2000)
Journal of Andrology
, vol.21
, Issue.3
, pp. 431-437
-
-
Sinha Hikim, A.P.1
Lue, Y.H.2
Wang, C.3
Reutrakul, V.4
Sangsuwan, R.5
Swerdloff, R.S.6
-
10
-
-
77951297155
-
Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats
-
L. Liu, Z. Jiang, J. Liu, X. Huang, T. Wang, and Y. Zhang et al. Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats Toxicology 271 2010 57 63
-
(2010)
Toxicology
, vol.271
, pp. 57-63
-
-
Liu, L.1
Jiang, Z.2
Liu, J.3
Huang, X.4
Wang, T.5
Zhang, Y.6
-
11
-
-
41849148999
-
Involvement of mitochondrial pathway in triptolide-induced cytotoxicity in human normal liver L-02 cells
-
DOI 10.1248/bpb.31.592
-
J. Yao, Z. Jiang, W. Duan, J. Huang, L. Zhang, and L. Hu et al. Involvement of mitochondrial pathway in triptolide-induced cytotoxicity in human normal liver L-02 cells Biol Pharm Bull 31 2008 592 597 (Pubitemid 351500486)
-
(2008)
Biological and Pharmaceutical Bulletin
, vol.31
, Issue.4
, pp. 592-597
-
-
Yao, J.1
Jiang, Z.2
Duan, W.3
Huang, J.4
Zhang, L.5
Hu, L.6
He, L.7
Li, F.8
Xiao, Y.9
Shu, B.10
Liu, C.11
-
12
-
-
84879288743
-
Gene expression profiling and pathway analysis of hepatotoxicity induced by triptolide in Wistar rats
-
J. Wang, Z. Jiang, J. Ji, X. Wang, T. Wang, and Y. Zhang et al. Gene expression profiling and pathway analysis of hepatotoxicity induced by triptolide in Wistar rats Food Chem Toxicol 58 2013 495 505
-
(2013)
Food Chem Toxicol
, vol.58
, pp. 495-505
-
-
Wang, J.1
Jiang, Z.2
Ji, J.3
Wang, X.4
Wang, T.5
Zhang, Y.6
-
13
-
-
28444469467
-
Protection effect of triptolide to liver injury in rats with severe acute pancreatitis
-
Y.F. Zhao, W.L. Zhai, S.J. Zhang, and X.P. Chen Protection effect of triptolide to liver injury in rats with severe acute pancreatitis Hepatobiliary Pancreat Dis Int 4 2005 604 608
-
(2005)
Hepatobiliary Pancreat Dis Int
, vol.4
, pp. 604-608
-
-
Zhao, Y.F.1
Zhai, W.L.2
Zhang, S.J.3
Chen, X.P.4
-
14
-
-
84860396737
-
Antifibrotic effects of triptolide on hepatic stellate cells and dimethylnitrosamine-intoxicated rats
-
L.W. Chong, Y.C. Hsu, Y.T. Chiu, K.C. Yang, and Y.T. Huang Antifibrotic effects of triptolide on hepatic stellate cells and dimethylnitrosamine- intoxicated rats Phytother Res 25 2011 990 999
-
(2011)
Phytother Res
, vol.25
, pp. 990-999
-
-
Chong, L.W.1
Hsu, Y.C.2
Chiu, Y.T.3
Yang, K.C.4
Huang, Y.T.5
-
15
-
-
77954069495
-
Mechanisms of immune-mediated liver injury
-
D.H. Adams, C. Ju, S.K. Ramaiah, J. Uetrecht, and H. Jaeschke Mechanisms of immune-mediated liver injury Toxicol Sci 115 2010 307 321
-
(2010)
Toxicol Sci
, vol.115
, pp. 307-321
-
-
Adams, D.H.1
Ju, C.2
Ramaiah, S.K.3
Uetrecht, J.4
Jaeschke, H.5
-
16
-
-
0031919849
-
Jaks and STATs: Biological implications
-
DOI 10.1146/annurev.immunol.16.1.293
-
W.J. Leonard, and J.J. O'Shea Jaks and STATs: biological implications Annu Rev Immunol 16 1998 293 322 (Pubitemid 28183367)
-
(1998)
Annual Review of Immunology
, vol.16
, pp. 293-322
-
-
Leonard, W.J.1
O'Shea, J.J.2
-
17
-
-
84863690997
-
The effects of TLR activation on T-cell development and differentiation
-
B. Jin, T. Sun, X.H. Yu, Y.X. Yang, and A.E. Yeo The effects of TLR activation on T-cell development and differentiation Clin Dev Immunol 2012 2012 836485
-
(2012)
Clin Dev Immunol
, vol.2012
, pp. 836485
-
-
Jin, B.1
Sun, T.2
Yu, X.H.3
Yang, Y.X.4
Yeo, A.E.5
-
18
-
-
77957667161
-
The potential of cytokines as safety biomarkers for drug-induced liver injury
-
H.G. Laverty, D.J. Antoine, C. Benson, M. Chaponda, D. Williams, and B. Kevin Park The potential of cytokines as safety biomarkers for drug-induced liver injury Eur J Clin Pharmacol 66 2010 961 976
-
(2010)
Eur J Clin Pharmacol
, vol.66
, pp. 961-976
-
-
Laverty, H.G.1
Antoine, D.J.2
Benson, C.3
Chaponda, M.4
Williams, D.5
Kevin Park, B.6
-
19
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
DOI 10.1038/ni1261, PII N1261
-
H. Park, Z. Li, X.O. Yang, S.H. Chang, R. Nurieva, and Y.H. Wang et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 Nat Immunol 6 2005 1133 1141 (Pubitemid 41541791)
-
(2005)
Nature Immunology
, vol.6
, Issue.11
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.-H.6
Wang, Y.7
Hood, L.8
Zhu, Z.9
Tian, Q.10
Dong, C.11
-
21
-
-
41549135632
-
The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation
-
DOI 10.1016/j.immuni.2008.03.004, PII S1074761308001192
-
W. Ouyang, J.K. Kolls, and Y. Zheng The biological functions of T helper 17 cell effector cytokines in inflammation Immunity 28 2008 454 467 (Pubitemid 351471762)
-
(2008)
Immunity
, vol.28
, Issue.4
, pp. 454-467
-
-
Ouyang, W.1
Kolls, J.K.2
Zheng, Y.3
-
22
-
-
33746342994
-
+ natural regulatory T cells in dominant self-tolerance and autoimmune disease
-
DOI 10.1111/j.0105-2896.2006.00427.x
-
+ natural regulatory T cells in dominant self-tolerance and autoimmune disease Immunol Rev 212 2006 8 27 (Pubitemid 44116697)
-
(2006)
Immunological Reviews
, vol.212
, pp. 8-27
-
-
Sakaguchi, S.1
Ono, M.2
Setoguchi, R.3
Yagi, H.4
Hori, S.5
Fehervari, Z.6
Shimizu, J.7
Takahashi, T.8
Nomura, T.9
-
23
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
E. Bettelli, Y. Carrier, W. Gao, T. Korn, T.B. Strom, and M. Oukka et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells Nature 441 2006 235 238
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
-
24
-
-
80053651902
-
Interleukin-17 exacerbates hepatic steatosis and inflammation in non-alcoholic fatty liver disease
-
Y. Tang, Z. Bian, L. Zhao, Y. Liu, S. Liang, and Q. Wang et al. Interleukin-17 exacerbates hepatic steatosis and inflammation in non-alcoholic fatty liver disease Clin Exp Immunol 166 2011 281 290
-
(2011)
Clin Exp Immunol
, vol.166
, pp. 281-290
-
-
Tang, Y.1
Bian, Z.2
Zhao, L.3
Liu, Y.4
Liang, S.5
Wang, Q.6
-
25
-
-
73449111925
-
Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells
-
D.M. Kuang, C. Peng, Q. Zhao, Y. Wu, M.S. Chen, and L. Zheng Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells Hepatology 51 2010 154 164
-
(2010)
Hepatology
, vol.51
, pp. 154-164
-
-
Kuang, D.M.1
Peng, C.2
Zhao, Q.3
Wu, Y.4
Chen, M.S.5
Zheng, L.6
-
26
-
-
77954817589
-
Interleukin-17 is involved in alpha-naphthylisothiocyanate-induced liver injury in mice
-
M. Kobayashi, S. Higuchi, K. Mizuno, K. Tsuneyama, T. Fukami, and M. Nakajima et al. Interleukin-17 is involved in alpha-naphthylisothiocyanate- induced liver injury in mice Toxicology 275 2010 50 57
-
(2010)
Toxicology
, vol.275
, pp. 50-57
-
-
Kobayashi, M.1
Higuchi, S.2
Mizuno, K.3
Tsuneyama, K.4
Fukami, T.5
Nakajima, M.6
-
27
-
-
70349298831
-
Halothane-induced liver injury is mediated by interleukin-17 in mice
-
E. Kobayashi, M. Kobayashi, K. Tsuneyama, T. Fukami, M. Nakajima, and T. Yokoi Halothane-induced liver injury is mediated by interleukin-17 in mice Toxicol Sci 111 2009 302 310
-
(2009)
Toxicol Sci
, vol.111
, pp. 302-310
-
-
Kobayashi, E.1
Kobayashi, M.2
Tsuneyama, K.3
Fukami, T.4
Nakajima, M.5
Yokoi, T.6
-
28
-
-
36349010120
-
A high-fat diet and regulatory T cells influence susceptibility to endotoxin-induced liver injury
-
DOI 10.1002/hep.21823
-
X. Ma, J. Hua, A.R. Mohamood, A.R. Hamad, R. Ravi, and Z. Li A high-fat diet and regulatory T cells influence susceptibility to endotoxin-induced liver injury Hepatology 46 2007 1519 1529 (Pubitemid 350155534)
-
(2007)
Hepatology
, vol.46
, Issue.5
, pp. 1519-1529
-
-
Ma, X.1
Hua, J.2
Mohamood, A.R.3
Hamad, A.R.A.4
Ravi, R.5
Li, Z.6
-
29
-
-
77954129292
-
Th17 cells: The emerging reciprocal partner of regulatory T cells in the liver
-
L. Zhao, K. Qiu de, and X. Ma Th17 cells: the emerging reciprocal partner of regulatory T cells in the liver J Dig Dis 11 2010 126 133
-
(2010)
J Dig Dis
, vol.11
, pp. 126-133
-
-
Zhao, L.1
De, Q.K.2
Ma, X.3
-
30
-
-
49349089380
-
Triptolide modulates T-cell inflammatory responses and ameliorates experimental autoimmune encephalomyelitis
-
Y. Wang, Y. Mei, D. Feng, and L. Xu Triptolide modulates T-cell inflammatory responses and ameliorates experimental autoimmune encephalomyelitis J Neurosci Res 86 2008 2441 2449
-
(2008)
J Neurosci Res
, vol.86
, pp. 2441-2449
-
-
Wang, Y.1
Mei, Y.2
Feng, D.3
Xu, L.4
-
31
-
-
79951851704
-
XPB, a subunit of TFIIH, is a target of the natural product triptolide
-
D.V. Titov, B. Gilman, Q.L. He, S. Bhat, W.K. Low, and Y. Dang et al. XPB, a subunit of TFIIH, is a target of the natural product triptolide Nat Chem Biol 7 2011 182 188
-
(2011)
Nat Chem Biol
, vol.7
, pp. 182-188
-
-
Titov, D.V.1
Gilman, B.2
He, Q.L.3
Bhat, S.4
Low, W.K.5
Dang, Y.6
-
32
-
-
84903182173
-
Metabolic pathways leading to detoxification of triptolide, a major active component of the herbal medicine Tripterygium wilfordii
-
F. Du, Z. Liu, X. Li, and J. Xing Metabolic pathways leading to detoxification of triptolide, a major active component of the herbal medicine Tripterygium wilfordii J Appl Toxicol 2013
-
(2013)
J Appl Toxicol
-
-
Du, F.1
Liu, Z.2
Li, X.3
Xing, J.4
-
33
-
-
80555126026
-
Nuclear factor-kappaB in immunity and inflammation: The Treg and Th17 connection
-
Q. Ruan, and Y.H. Chen Nuclear factor-kappaB in immunity and inflammation: the Treg and Th17 connection Adv Exp Med Biol 946 2012 207 221
-
(2012)
Adv Exp Med Biol
, vol.946
, pp. 207-221
-
-
Ruan, Q.1
Chen, Y.H.2
-
34
-
-
84875700814
-
P53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice
-
J.S. Park, M.A. Lim, M.L. Cho, J.G. Ryu, Y.M. Moon, and J.Y. Jhun et al. p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice Arthritis Rheum 65 2013 949 959
-
(2013)
Arthritis Rheum
, vol.65
, pp. 949-959
-
-
Park, J.S.1
Lim, M.A.2
Cho, M.L.3
Ryu, J.G.4
Moon, Y.M.5
Jhun, J.Y.6
-
35
-
-
0034005303
-
Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: Potential mechanism for sensitization to liver damage
-
M. Guebre-Xabier, S. Yang, H.Z. Lin, R. Schwenk, U. Krzych, and A.M. Diehl Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: potential mechanism for sensitization to liver damage Hepatology 31 2000 633 640 (Pubitemid 30118631)
-
(2000)
Hepatology
, vol.31
, Issue.3
, pp. 633-640
-
-
Guebre-Xabier, M.1
Yang, S.2
Lin, H.Z.3
Schwenk, R.4
Krzych, U.5
Diehl, A.M.6
-
36
-
-
84880091690
-
Restoring the Treg cell to Th17 cell ratio may alleviate HBV-related acute-on-chronic liver failure
-
Y.H. Niu, D.L. Yin, H.L. Liu, R.T. Yi, Y.C. Yang, and H.A. Xue et al. Restoring the Treg cell to Th17 cell ratio may alleviate HBV-related acute-on-chronic liver failure World J Gastroenterol 19 2013 4146 4154
-
(2013)
World J Gastroenterol
, vol.19
, pp. 4146-4154
-
-
Niu, Y.H.1
Yin, D.L.2
Liu, H.L.3
Yi, R.T.4
Yang, Y.C.5
Xue, H.A.6
|