메뉴 건너뛰기




Volumn 93, Issue , 2014, Pages 245-251

Th17/Treg imbalance in triptolide-induced liver injury

Author keywords

Hepatotoxicity; Regulatory T cells; Th17 cells; Th17 Treg imbalance; Triptolide

Indexed keywords

DITERPENE; EPOXIDE; IL10 PROTEIN, MOUSE; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 10; INTERLEUKIN 17; PHENANTHRENE DERIVATIVE; TRANSCRIPTION FACTOR; TRIPTOLIDE;

EID: 84894202522     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2014.01.006     Document Type: Article
Times cited : (63)

References (36)
  • 1
    • 0034909663 scopus 로고    scopus 로고
    • Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium Wilfordii Hook F
    • B.J. Chen Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium wilfordii Hook F Leuk Lymphoma 42 2001 253 265 (Pubitemid 32725582)
    • (2001) Leukemia and Lymphoma , vol.42 , Issue.3 , pp. 253-265
    • Chen, B.J.1
  • 2
    • 79952106497 scopus 로고    scopus 로고
    • Triptolide and its expanding multiple pharmacological functions
    • Q. Liu Triptolide and its expanding multiple pharmacological functions Int Immunopharmacol 11 2011 377 383
    • (2011) Int Immunopharmacol , vol.11 , pp. 377-383
    • Liu, Q.1
  • 3
    • 78650418550 scopus 로고    scopus 로고
    • The safety and effectiveness of a chloroform/methanol extract of Tripterygium wilfordii Hook F (T2) plus methotrexate in treating rheumatoid arthritis
    • W. Zhang, Q. Shi, L.D. Zhao, Y. Li, F.L. Tang, and F.C. Zhang et al. The safety and effectiveness of a chloroform/methanol extract of Tripterygium wilfordii Hook F (T2) plus methotrexate in treating rheumatoid arthritis J Clin Rheumatol 16 2010 375 378
    • (2010) J Clin Rheumatol , vol.16 , pp. 375-378
    • Zhang, W.1    Shi, Q.2    Zhao, L.D.3    Li, Y.4    Tang, F.L.5    Zhang, F.C.6
  • 4
    • 33847278423 scopus 로고    scopus 로고
    • Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)
    • DOI 10.1016/j.phytochem.2006.11.029, PII S0031942206007370
    • A.M. Brinker, J. Ma, P.E. Lipsky, and I. Raskin Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae) Phytochemistry 68 2007 732 766 (Pubitemid 46330437)
    • (2007) Phytochemistry , vol.68 , Issue.6 , pp. 732-766
    • Brinker, A.M.1    Ma, J.2    Lipsky, P.E.3    Raskin, I.4
  • 5
    • 84863263731 scopus 로고    scopus 로고
    • Triptolide attenuate the oxidative stress induced by LPS/D-GalN in mice
    • Y. Lu, X. Bao, T. Sun, J. Xu, W. Zheng, and P. Shen Triptolide attenuate the oxidative stress induced by LPS/D-GalN in mice J Cell Biochem 113 2012 1022 1033
    • (2012) J Cell Biochem , vol.113 , pp. 1022-1033
    • Lu, Y.1    Bao, X.2    Sun, T.3    Xu, J.4    Zheng, W.5    Shen, P.6
  • 6
    • 79952489486 scopus 로고    scopus 로고
    • Triptolide alleviates hepatic ischemia/reperfusion injury by attenuating oxidative stress and inhibiting NF-kappaB activity in mice
    • C. Wu, P. Wang, J. Rao, Z. Wang, C. Zhang, and L. Lu et al. Triptolide alleviates hepatic ischemia/reperfusion injury by attenuating oxidative stress and inhibiting NF-kappaB activity in mice J Surg Res 166 2011 e205 e213
    • (2011) J Surg Res , vol.166
    • Wu, C.1    Wang, P.2    Rao, J.3    Wang, Z.4    Zhang, C.5    Lu, L.6
  • 7
    • 36649020474 scopus 로고    scopus 로고
    • Triptolide inhibits NF-kappaB activation and reduces injury of donor lung induced by ischemia/reperfusion
    • J.K. He, S.D. Yu, H.J. Zhu, J.C. Wu, and Z.H. Qin Triptolide inhibits NF-kappaB activation and reduces injury of donor lung induced by ischemia/reperfusion Acta Pharmacol Sin 28 2007 1919 1923
    • (2007) Acta Pharmacol Sin , vol.28 , pp. 1919-1923
    • He, J.K.1    Yu, S.D.2    Zhu, H.J.3    Wu, J.C.4    Qin, Z.H.5
  • 8
    • 80054908941 scopus 로고    scopus 로고
    • Inhibition of mitochondrial respiratory chain is involved in triptolide-induced liver injury
    • Q. Fu, X. Huang, B. Shu, M. Xue, P. Zhang, and T. Wang et al. Inhibition of mitochondrial respiratory chain is involved in triptolide-induced liver injury Fitoterapia 82 2011 1241 1248
    • (2011) Fitoterapia , vol.82 , pp. 1241-1248
    • Fu, Q.1    Huang, X.2    Shu, B.3    Xue, M.4    Zhang, P.5    Wang, T.6
  • 9
    • 0342804486 scopus 로고    scopus 로고
    • Posttesticular antifertility action of triptolide in the male rat: Evidence for severe impairment of cauda epididymal sperm ultrastructure
    • A.P. Hikim, Y.H. Lue, C. Wang, V. Reutrakul, R. Sangsuwan, and R.S. Swerdloff Posttesticular antifertility action of triptolide in the male rat: evidence for severe impairment of cauda epididymal sperm ultrastructure J Androl 21 2000 431 437 (Pubitemid 30252515)
    • (2000) Journal of Andrology , vol.21 , Issue.3 , pp. 431-437
    • Sinha Hikim, A.P.1    Lue, Y.H.2    Wang, C.3    Reutrakul, V.4    Sangsuwan, R.5    Swerdloff, R.S.6
  • 10
    • 77951297155 scopus 로고    scopus 로고
    • Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats
    • L. Liu, Z. Jiang, J. Liu, X. Huang, T. Wang, and Y. Zhang et al. Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats Toxicology 271 2010 57 63
    • (2010) Toxicology , vol.271 , pp. 57-63
    • Liu, L.1    Jiang, Z.2    Liu, J.3    Huang, X.4    Wang, T.5    Zhang, Y.6
  • 12
    • 84879288743 scopus 로고    scopus 로고
    • Gene expression profiling and pathway analysis of hepatotoxicity induced by triptolide in Wistar rats
    • J. Wang, Z. Jiang, J. Ji, X. Wang, T. Wang, and Y. Zhang et al. Gene expression profiling and pathway analysis of hepatotoxicity induced by triptolide in Wistar rats Food Chem Toxicol 58 2013 495 505
    • (2013) Food Chem Toxicol , vol.58 , pp. 495-505
    • Wang, J.1    Jiang, Z.2    Ji, J.3    Wang, X.4    Wang, T.5    Zhang, Y.6
  • 13
    • 28444469467 scopus 로고    scopus 로고
    • Protection effect of triptolide to liver injury in rats with severe acute pancreatitis
    • Y.F. Zhao, W.L. Zhai, S.J. Zhang, and X.P. Chen Protection effect of triptolide to liver injury in rats with severe acute pancreatitis Hepatobiliary Pancreat Dis Int 4 2005 604 608
    • (2005) Hepatobiliary Pancreat Dis Int , vol.4 , pp. 604-608
    • Zhao, Y.F.1    Zhai, W.L.2    Zhang, S.J.3    Chen, X.P.4
  • 14
    • 84860396737 scopus 로고    scopus 로고
    • Antifibrotic effects of triptolide on hepatic stellate cells and dimethylnitrosamine-intoxicated rats
    • L.W. Chong, Y.C. Hsu, Y.T. Chiu, K.C. Yang, and Y.T. Huang Antifibrotic effects of triptolide on hepatic stellate cells and dimethylnitrosamine- intoxicated rats Phytother Res 25 2011 990 999
    • (2011) Phytother Res , vol.25 , pp. 990-999
    • Chong, L.W.1    Hsu, Y.C.2    Chiu, Y.T.3    Yang, K.C.4    Huang, Y.T.5
  • 16
    • 0031919849 scopus 로고    scopus 로고
    • Jaks and STATs: Biological implications
    • DOI 10.1146/annurev.immunol.16.1.293
    • W.J. Leonard, and J.J. O'Shea Jaks and STATs: biological implications Annu Rev Immunol 16 1998 293 322 (Pubitemid 28183367)
    • (1998) Annual Review of Immunology , vol.16 , pp. 293-322
    • Leonard, W.J.1    O'Shea, J.J.2
  • 17
    • 84863690997 scopus 로고    scopus 로고
    • The effects of TLR activation on T-cell development and differentiation
    • B. Jin, T. Sun, X.H. Yu, Y.X. Yang, and A.E. Yeo The effects of TLR activation on T-cell development and differentiation Clin Dev Immunol 2012 2012 836485
    • (2012) Clin Dev Immunol , vol.2012 , pp. 836485
    • Jin, B.1    Sun, T.2    Yu, X.H.3    Yang, Y.X.4    Yeo, A.E.5
  • 21
    • 41549135632 scopus 로고    scopus 로고
    • The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation
    • DOI 10.1016/j.immuni.2008.03.004, PII S1074761308001192
    • W. Ouyang, J.K. Kolls, and Y. Zheng The biological functions of T helper 17 cell effector cytokines in inflammation Immunity 28 2008 454 467 (Pubitemid 351471762)
    • (2008) Immunity , vol.28 , Issue.4 , pp. 454-467
    • Ouyang, W.1    Kolls, J.K.2    Zheng, Y.3
  • 23
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • E. Bettelli, Y. Carrier, W. Gao, T. Korn, T.B. Strom, and M. Oukka et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells Nature 441 2006 235 238
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6
  • 24
    • 80053651902 scopus 로고    scopus 로고
    • Interleukin-17 exacerbates hepatic steatosis and inflammation in non-alcoholic fatty liver disease
    • Y. Tang, Z. Bian, L. Zhao, Y. Liu, S. Liang, and Q. Wang et al. Interleukin-17 exacerbates hepatic steatosis and inflammation in non-alcoholic fatty liver disease Clin Exp Immunol 166 2011 281 290
    • (2011) Clin Exp Immunol , vol.166 , pp. 281-290
    • Tang, Y.1    Bian, Z.2    Zhao, L.3    Liu, Y.4    Liang, S.5    Wang, Q.6
  • 25
    • 73449111925 scopus 로고    scopus 로고
    • Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells
    • D.M. Kuang, C. Peng, Q. Zhao, Y. Wu, M.S. Chen, and L. Zheng Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells Hepatology 51 2010 154 164
    • (2010) Hepatology , vol.51 , pp. 154-164
    • Kuang, D.M.1    Peng, C.2    Zhao, Q.3    Wu, Y.4    Chen, M.S.5    Zheng, L.6
  • 26
    • 77954817589 scopus 로고    scopus 로고
    • Interleukin-17 is involved in alpha-naphthylisothiocyanate-induced liver injury in mice
    • M. Kobayashi, S. Higuchi, K. Mizuno, K. Tsuneyama, T. Fukami, and M. Nakajima et al. Interleukin-17 is involved in alpha-naphthylisothiocyanate- induced liver injury in mice Toxicology 275 2010 50 57
    • (2010) Toxicology , vol.275 , pp. 50-57
    • Kobayashi, M.1    Higuchi, S.2    Mizuno, K.3    Tsuneyama, K.4    Fukami, T.5    Nakajima, M.6
  • 28
    • 36349010120 scopus 로고    scopus 로고
    • A high-fat diet and regulatory T cells influence susceptibility to endotoxin-induced liver injury
    • DOI 10.1002/hep.21823
    • X. Ma, J. Hua, A.R. Mohamood, A.R. Hamad, R. Ravi, and Z. Li A high-fat diet and regulatory T cells influence susceptibility to endotoxin-induced liver injury Hepatology 46 2007 1519 1529 (Pubitemid 350155534)
    • (2007) Hepatology , vol.46 , Issue.5 , pp. 1519-1529
    • Ma, X.1    Hua, J.2    Mohamood, A.R.3    Hamad, A.R.A.4    Ravi, R.5    Li, Z.6
  • 29
    • 77954129292 scopus 로고    scopus 로고
    • Th17 cells: The emerging reciprocal partner of regulatory T cells in the liver
    • L. Zhao, K. Qiu de, and X. Ma Th17 cells: the emerging reciprocal partner of regulatory T cells in the liver J Dig Dis 11 2010 126 133
    • (2010) J Dig Dis , vol.11 , pp. 126-133
    • Zhao, L.1    De, Q.K.2    Ma, X.3
  • 30
    • 49349089380 scopus 로고    scopus 로고
    • Triptolide modulates T-cell inflammatory responses and ameliorates experimental autoimmune encephalomyelitis
    • Y. Wang, Y. Mei, D. Feng, and L. Xu Triptolide modulates T-cell inflammatory responses and ameliorates experimental autoimmune encephalomyelitis J Neurosci Res 86 2008 2441 2449
    • (2008) J Neurosci Res , vol.86 , pp. 2441-2449
    • Wang, Y.1    Mei, Y.2    Feng, D.3    Xu, L.4
  • 31
    • 79951851704 scopus 로고    scopus 로고
    • XPB, a subunit of TFIIH, is a target of the natural product triptolide
    • D.V. Titov, B. Gilman, Q.L. He, S. Bhat, W.K. Low, and Y. Dang et al. XPB, a subunit of TFIIH, is a target of the natural product triptolide Nat Chem Biol 7 2011 182 188
    • (2011) Nat Chem Biol , vol.7 , pp. 182-188
    • Titov, D.V.1    Gilman, B.2    He, Q.L.3    Bhat, S.4    Low, W.K.5    Dang, Y.6
  • 32
    • 84903182173 scopus 로고    scopus 로고
    • Metabolic pathways leading to detoxification of triptolide, a major active component of the herbal medicine Tripterygium wilfordii
    • F. Du, Z. Liu, X. Li, and J. Xing Metabolic pathways leading to detoxification of triptolide, a major active component of the herbal medicine Tripterygium wilfordii J Appl Toxicol 2013
    • (2013) J Appl Toxicol
    • Du, F.1    Liu, Z.2    Li, X.3    Xing, J.4
  • 33
    • 80555126026 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in immunity and inflammation: The Treg and Th17 connection
    • Q. Ruan, and Y.H. Chen Nuclear factor-kappaB in immunity and inflammation: the Treg and Th17 connection Adv Exp Med Biol 946 2012 207 221
    • (2012) Adv Exp Med Biol , vol.946 , pp. 207-221
    • Ruan, Q.1    Chen, Y.H.2
  • 34
    • 84875700814 scopus 로고    scopus 로고
    • P53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice
    • J.S. Park, M.A. Lim, M.L. Cho, J.G. Ryu, Y.M. Moon, and J.Y. Jhun et al. p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice Arthritis Rheum 65 2013 949 959
    • (2013) Arthritis Rheum , vol.65 , pp. 949-959
    • Park, J.S.1    Lim, M.A.2    Cho, M.L.3    Ryu, J.G.4    Moon, Y.M.5    Jhun, J.Y.6
  • 35
    • 0034005303 scopus 로고    scopus 로고
    • Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: Potential mechanism for sensitization to liver damage
    • M. Guebre-Xabier, S. Yang, H.Z. Lin, R. Schwenk, U. Krzych, and A.M. Diehl Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: potential mechanism for sensitization to liver damage Hepatology 31 2000 633 640 (Pubitemid 30118631)
    • (2000) Hepatology , vol.31 , Issue.3 , pp. 633-640
    • Guebre-Xabier, M.1    Yang, S.2    Lin, H.Z.3    Schwenk, R.4    Krzych, U.5    Diehl, A.M.6
  • 36
    • 84880091690 scopus 로고    scopus 로고
    • Restoring the Treg cell to Th17 cell ratio may alleviate HBV-related acute-on-chronic liver failure
    • Y.H. Niu, D.L. Yin, H.L. Liu, R.T. Yi, Y.C. Yang, and H.A. Xue et al. Restoring the Treg cell to Th17 cell ratio may alleviate HBV-related acute-on-chronic liver failure World J Gastroenterol 19 2013 4146 4154
    • (2013) World J Gastroenterol , vol.19 , pp. 4146-4154
    • Niu, Y.H.1    Yin, D.L.2    Liu, H.L.3    Yi, R.T.4    Yang, Y.C.5    Xue, H.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.