메뉴 건너뛰기




Volumn 19, Issue 26, 2013, Pages 4146-4154

Restoring the Treg cell to Th17 cell ratio may alleviate HBVrelated acute-on-chronic liver failure

Author keywords

Acute on chronic liver failure; Hepatitis B virus; Regulatory T cells; T helper 17 cells; Treg cell to Th17 cell ratio

Indexed keywords

BILIRUBIN; CREATININE; FLUORESCEIN ISOTHIOCYANATE; INTERLEUKIN 17; TRANSCRIPTION FACTOR FOXP3; VIRUS DNA;

EID: 84880091690     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v19.i26.4146     Document Type: Article
Times cited : (33)

References (36)
  • 2
    • 0036184310 scopus 로고    scopus 로고
    • Acute-on-chronic liver failure: Pathophysiological basis of therapeutic options
    • [PMID: 11867872 DOI: 10.1159/000047017]
    • Jalan R, Williams R. Acute-on-chronic liver failure: pathophysiological basis of therapeutic options. Blood Purif 2002; 20: 252-261 [PMID: 11867872 DOI: 10.1159/000047017]
    • (2002) Blood Purif , vol.20 , pp. 252-261
    • Jalan, R.1    Williams, R.2
  • 3
    • 79952211991 scopus 로고    scopus 로고
    • Tenofovir improves the outcome in patients with spontaneous reactivation of hepatitis B presenting as acute-on-chronic liver failure
    • [PMID: 21294143 DOI: 10.1002/hep.24109]
    • Garg H, Sarin SK, Kumar M, Garg V, Sharma BC, Kumar A. Tenofovir improves the outcome in patients with spontaneous reactivation of hepatitis B presenting as acute-on-chronic liver failure. Hepatology 2011; 53: 774-780 [PMID: 21294143 DOI: 10.1002/hep.24109]
    • (2011) Hepatology , vol.53 , pp. 774-780
    • Garg, H.1    Sarin, S.K.2    Kumar, M.3    Garg, V.4    Sharma, B.C.5    Kumar, A.6
  • 4
    • 84865470803 scopus 로고    scopus 로고
    • Nucleoside analogues improve the short-term and long-term prognosis of patients with hepatitis B virus-related acute-onchronic liver failure
    • [PMID: 22002708 DOI: 10.1007/s10238-011-0160-7]
    • Chen T, He Y, Liu X, Yan Z, Wang K, Liu H, Zhang S, Zhao Y. Nucleoside analogues improve the short-term and long-term prognosis of patients with hepatitis B virus-related acute-onchronic liver failure. Clin Exp Med 2012; 12: 159-164 [PMID: 22002708 DOI: 10.1007/s10238-011-0160-7]
    • (2012) Clin Exp Med , vol.12 , pp. 159-164
    • Chen, T.1    He, Y.2    Liu, X.3    Yan, Z.4    Wang, K.5    Liu, H.6    Zhang, S.7    Zhao, Y.8
  • 5
    • 84863137243 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor mobilizes CD34(+) cells and improves survival of patients with acute-on-chronic liver failure
    • [PMID: 22119930]
    • Garg V, Garg H, Khan A, Trehanpati N, Kumar A, Sharma BC, Sakhuja P, Sarin SK. Granulocyte colony-stimulating factor mobilizes CD34(+) cells and improves survival of patients with acute-on-chronic liver failure. Gastroenterology 2012; 142: 505-512. e1 [PMID: 22119930]
    • (2012) Gastroenterology , vol.142
    • Garg, V.1    Garg, H.2    Khan, A.3    Trehanpati, N.4    Kumar, A.5    Sharma, B.C.6    Sakhuja, P.7    Sarin, S.K.8
  • 6
    • 80054740657 scopus 로고    scopus 로고
    • Acute-on-chronic liver failure before liver transplantation: Impact on posttransplant outcomes
    • [PMID: 21869735 DOI: 10.1097/ TP.0b013e31822e6eda]
    • Bahirwani R, Shaked O, Bewtra M, Forde K, Reddy KR. Acute-on-chronic liver failure before liver transplantation: impact on posttransplant outcomes. Transplantation 2011; 92: 952-957 [PMID: 21869735 DOI: 10.1097/ TP.0b013e31822e6eda]
    • (2011) Transplantation , vol.92 , pp. 952-957
    • Bahirwani, R.1    Shaked, O.2    Bewtra, M.3    Forde, K.4    Reddy, K.R.5
  • 7
    • 29544448330 scopus 로고    scopus 로고
    • Effects of artificial liver support system on patients with acute or chronic liver failure
    • [PMID: 16387120 DOI: 10.1016/j. transproceed.2005.11.044]
    • Du WB, Li LJ, Huang JR, Yang Q, Liu XL, Li J, Chen YM, Cao HC, Xu W, Fu SZ, Chen YG. Effects of artificial liver support system on patients with acute or chronic liver failure. Transplant Proc 2005; 37: 4359-4364 [PMID: 16387120 DOI: 10.1016/j. transproceed.2005.11.044]
    • (2005) Transplant Proc , vol.37 , pp. 4359-4364
    • Du, W.B.1    Li, L.J.2    Huang, J.R.3    Yang, Q.4    Liu, X.L.5    Li, J.6    Chen, Y.M.7    Cao, H.C.8    Xu, W.9    Fu, S.Z.10    Chen, Y.G.11
  • 8
    • 0035189597 scopus 로고    scopus 로고
    • Chronic hepatitis B
    • [PMID: 11732013 DOI: 10.1053/ jhep.2001.29401]
    • Lok AS, McMahon BJ. Chronic hepatitis B. Hepatology 2001; 34: 1225-1241 [PMID: 11732013 DOI: 10.1053/ jhep.2001.29401]
    • (2001) Hepatology , vol.34 , pp. 1225-1241
    • Lok, A.S.1    McMahon, B.J.2
  • 9
    • 0036293243 scopus 로고    scopus 로고
    • Global control of hepatitis B virus infection
    • [PMID: 12127351 DOI: 10.1016/S1473-3099(02)00315-8]
    • Kao JH, Chen DS. Global control of hepatitis B virus infection. Lancet Infect Dis 2002; 2: 395-403 [PMID: 12127351 DOI: 10.1016/S1473-3099(02)00315-8]
    • (2002) Lancet Infect Dis , vol.2 , pp. 395-403
    • Kao, J.H.1    Chen, D.S.2
  • 10
    • 0036461318 scopus 로고    scopus 로고
    • Immunology of hepatitis B infection
    • [PMID: 11892495 DOI: 10.1016/S1473-3099(01)00172-4]
    • Jung MC, Pape GR. Immunology of hepatitis B infection. Lancet Infect Dis 2002; 2: 43-50 [PMID: 11892495 DOI: 10.1016/S1473-3099(01)00172-4]
    • (2002) Lancet Infect Dis , vol.2 , pp. 43-50
    • Jung, M.C.1    Pape, G.R.2
  • 12
  • 13
    • 0033807687 scopus 로고    scopus 로고
    • The systemic inflammatory response syndrome in acute liver failure
    • [PMID: 11003617 DOI: 10.1053/jhep.2000.17687]
    • Rolando N, Wade J, Davalos M, Wendon J, Philpott-Howard J, Williams R. The systemic inflammatory response syndrome in acute liver failure. Hepatology 2000; 32: 734-739 [PMID: 11003617 DOI: 10.1053/jhep.2000.17687]
    • (2000) Hepatology , vol.32 , pp. 734-739
    • Rolando, N.1    Wade, J.2    Davalos, M.3    Wendon, J.4    Philpott-Howard, J.5    Williams, R.6
  • 14
    • 73449125874 scopus 로고    scopus 로고
    • Interleukin-17-producing CD4(+) T cells increase with severity of liver damage in patients with chronic hepatitis B
    • [PMID: 19842207 DOI: 10.1002/hep.23273]
    • Zhang JY, Zhang Z, Lin F, Zou ZS, Xu RN, Jin L, Fu JL, Shi F, Shi M, Wang HF, Wang FS. Interleukin-17-producing CD4(+) T cells increase with severity of liver damage in patients with chronic hepatitis B. Hepatology 2010; 51: 81-91 [PMID: 19842207 DOI: 10.1002/hep.23273]
    • (2010) Hepatology , vol.51 , pp. 81-91
    • Zhang, J.Y.1    Zhang, Z.2    Lin, F.3    Zou, Z.S.4    Xu, R.N.5    Jin, L.6    Fu, J.L.7    Shi, F.8    Shi, M.9    Wang, H.F.10    Wang, F.S.11
  • 15
    • 77956264119 scopus 로고    scopus 로고
    • Involvement of Th17 and Th1 effector responses in patients with Hepatitis B
    • [PMID: 20393789 DOI: 10.1007/s10875-010-9416-3]
    • Ye Y, Xie X, Yu J, Zhou L, Xie H, Jiang G, Yu X, Zhang W, Wu J, Zheng S. Involvement of Th17 and Th1 effector responses in patients with Hepatitis B. J Clin Immunol 2010; 30: 546-555 [PMID: 20393789 DOI: 10.1007/s10875-010-9416-3]
    • (2010) J Clin Immunol , vol.30 , pp. 546-555
    • Ye, Y.1    Xie, X.2    Yu, J.3    Zhou, L.4    Xie, H.5    Jiang, G.6    Yu, X.7    Zhang, W.8    Wu, J.9    Zheng, S.10
  • 16
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • [PMID: 12658273 DOI: 10.1038/nri1032]
    • Bluestone JA, Abbas AK. Natural versus adaptive regulatory T cells. Nat Rev Immunol 2003; 3: 253-257 [PMID: 12658273 DOI: 10.1038/nri1032]
    • (2003) Nat Rev Immunol , vol.3 , pp. 253-257
    • Bluestone, J.A.1    Abbas, A.K.2
  • 17
    • 33947720523 scopus 로고    scopus 로고
    • Development in motion: Helper T cells at work
    • [PMID: 17418783 DOI: 10.1016/ j. cell.2007.03.019]
    • Reiner SL. Development in motion: helper T cells at work. Cell 2007; 129: 33-36 [PMID: 17418783 DOI: 10.1016/ j. cell.2007.03.019]
    • (2007) Cell , vol.129 , pp. 33-36
    • Reiner, S.L.1
  • 18
    • 33745323050 scopus 로고    scopus 로고
    • Circulating and liver resident CD4+CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B
    • [PMID: 16785573]
    • Xu D, Fu J, Jin L, Zhang H, Zhou C, Zou Z, Zhao JM, Zhang B, Shi M, Ding X, Tang Z, Fu YX, Wang FS. Circulating and liver resident CD4+CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B. J Immunol 2006; 177: 739-747 [PMID: 16785573]
    • (2006) J Immunol , vol.177 , pp. 739-747
    • Xu, D.1    Fu, J.2    Jin, L.3    Zhang, H.4    Zhou, C.5    Zou, Z.6    Zhao, J.M.7    Zhang, B.8    Shi, M.9    Ding, X.10    Tang, Z.11    Fu, Y.X.12    Wang, F.S.13
  • 19
    • 80051802248 scopus 로고    scopus 로고
    • The balance between intrahepatic IL-17(+) T cells and Foxp3(+) regulatory T cells plays an important role in HBV-related end-stage liver disease
    • [PMID: 21851644 DOI: 10.1186/1471-2172-12-47]
    • Niu Y, Liu H, Yin D, Yi R, Chen T, Xue H, Zhang S, Lin S, Zhao Y. The balance between intrahepatic IL-17(+) T cells and Foxp3(+) regulatory T cells plays an important role in HBV-related end-stage liver disease. BMC Immunol 2011; 12: 47 [PMID: 21851644 DOI: 10.1186/1471-2172-12-47]
    • (2011) BMC Immunol , vol.12 , pp. 47
    • Niu, Y.1    Liu, H.2    Yin, D.3    Yi, R.4    Chen, T.5    Xue, H.6    Zhang, S.7    Lin, S.8    Zhao, Y.9
  • 20
    • 80051711559 scopus 로고    scopus 로고
    • The ratio of Th-17 to Treg cells is associated with survival of patients with acute-on-chronic hepatitis B liver failure
    • [PMID: 21721931 DOI: 10.1089/ vim.2010.0135]
    • Zhai S, Zhang L, Dang S, Yu Y, Zhao Z, Zhao W, Liu L. The ratio of Th-17 to Treg cells is associated with survival of patients with acute-on-chronic hepatitis B liver failure. Viral Immunol 2011; 24: 303-310 [PMID: 21721931 DOI: 10.1089/ vim.2010.0135]
    • (2011) Viral Immunol , vol.24 , pp. 303-310
    • Zhai, S.1    Zhang, L.2    Dang, S.3    Yu, Y.4    Zhao, Z.5    Zhao, W.6    Liu, L.7
  • 23
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • [PMID: 16648838 DOI: 10.1038/nature04753]
    • Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006; 441: 235-238 [PMID: 16648838 DOI: 10.1038/nature04753]
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 24
    • 67349114782 scopus 로고    scopus 로고
    • FOXP3 and the regulation of Treg/ Th17 differentiation
    • [PMID: 19371792 DOI: 10.1016/j. micinf.2009.04.002]
    • Ziegler SF, Buckner JH. FOXP3 and the regulation of Treg/ Th17 differentiation. Microbes Infect 2009; 11: 594-598 [PMID: 19371792 DOI: 10.1016/j. micinf.2009.04.002]
    • (2009) Microbes Infect , vol.11 , pp. 594-598
    • Ziegler, S.F.1    Buckner, J.H.2
  • 25
    • 77954096689 scopus 로고    scopus 로고
    • IL-6: Regulator of Treg/Th17 balance
    • [PMID: 20583029 DOI: 10.1002/eji.201040391]
    • Kimura A, Kishimoto T. IL-6: regulator of Treg/Th17 balance. Eur J Immunol 2010; 40: 1830-1835 [PMID: 20583029 DOI: 10.1002/eji.201040391]
    • (2010) Eur J Immunol , vol.40 , pp. 1830-1835
    • Kimura, A.1    Kishimoto, T.2
  • 26
    • 72949106340 scopus 로고    scopus 로고
    • Interplay between the TH17 and TReg cell lineages: A (co-)evolutionary perspective
    • [PMID: 19935807]
    • Weaver CT, Hatton RD. Interplay between the TH17 and TReg cell lineages: a (co-)evolutionary perspective. Nat Rev Immunol 2009; 9: 883-889 [PMID: 19935807]
    • (2009) Nat Rev Immunol , vol.9 , pp. 883-889
    • Weaver, C.T.1    Hatton, R.D.2
  • 27
    • 34447503805 scopus 로고    scopus 로고
    • Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
    • [PMID: 17569825 DOI: 10.1126/science.1145697]
    • Mucida D, Park Y, Kim G, Turovskaya O, Scott I, Kronenberg M, Cheroutre H. Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 2007; 317: 256-260 [PMID: 17569825 DOI: 10.1126/science.1145697]
    • (2007) Science , vol.317 , pp. 256-260
    • Mucida, D.1    Park, Y.2    Kim, G.3    Turovskaya, O.4    Scott, I.5    Kronenberg, M.6    Cheroutre, H.7
  • 28
    • 27544465354 scopus 로고    scopus 로고
    • A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
    • [PMID: 16200068 DOI: 10.1038/ni1261]
    • Park H, Li Z, Yang XO, Chang SH, Nurieva R, Wang YH, Wang Y, Hood L, Zhu Z, Tian Q, Dong C. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 2005; 6: 1133-1141 [PMID: 16200068 DOI: 10.1038/ni1261]
    • (2005) Nat Immunol , vol.6 , pp. 1133-1141
    • Park, H.1    Li, Z.2    Yang, X.O.3    Chang, S.H.4    Nurieva, R.5    Wang, Y.H.6    Wang, Y.7    Hood, L.8    Zhu, Z.9    Tian, Q.10    Dong, C.11
  • 29
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • [PMID: 16200070 DOI: 10.1038/ni1254]
    • Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005; 6: 1123-1132 [PMID: 16200070 DOI: 10.1038/ni1254]
    • (2005) Nat Immunol , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6    Weaver, C.T.7
  • 30
    • 33746342994 scopus 로고    scopus 로고
    • Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease
    • [PMID: 16903903 DOI: 10.1111/j.0105-2896.2006.00427. x]
    • Sakaguchi S, Ono M, Setoguchi R, Yagi H, Hori S, Fehervari Z, Shimizu J, Takahashi T, Nomura T. Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol Rev 2006; 212: 8-27 [PMID: 16903903 DOI: 10.1111/j.0105-2896.2006.00427. x]
    • (2006) Immunol Rev , vol.212 , pp. 8-27
    • Sakaguchi, S.1    Ono, M.2    Setoguchi, R.3    Yagi, H.4    Hori, S.5    Fehervari, Z.6    Shimizu, J.7    Takahashi, T.8    Nomura, T.9
  • 31
    • 34248572345 scopus 로고    scopus 로고
    • T(H)-17 cells in the circle of immunity and autoimmunity
    • [PMID: 17375096 DOI: 10.1038/ni0407-345]
    • Bettelli E, Oukka M, Kuchroo VK. T(H)-17 cells in the circle of immunity and autoimmunity. Nat Immunol 2007; 8: 345-350 [PMID: 17375096 DOI: 10.1038/ni0407-345]
    • (2007) Nat Immunol , vol.8 , pp. 345-350
    • Bettelli, E.1    Oukka, M.2    Kuchroo, V.K.3
  • 32
    • 73249122393 scopus 로고    scopus 로고
    • Antigen-specific Treg regulate Th17-mediated lung neutrophilic inflammation, B-cell recruitment and polymeric IgA and IgM levels in the airways
    • [PMID: 19830731 DOI: 10.1002/eji.200939498]
    • Jaffar Z, Ferrini ME, Girtsman TA, Roberts K. Antigen-specific Treg regulate Th17-mediated lung neutrophilic inflammation, B-cell recruitment and polymeric IgA and IgM levels in the airways. Eur J Immunol 2009; 39: 3307-3314 [PMID: 19830731 DOI: 10.1002/eji.200939498]
    • (2009) Eur J Immunol , vol.39 , pp. 3307-3314
    • Jaffar, Z.1    Ferrini, M.E.2    Girtsman, T.A.3    Roberts, K.4
  • 33
    • 84862833461 scopus 로고    scopus 로고
    • Recovery of the immune balance between Th17 and regulatory T cells as a treatment for systemic lupus erythematosus
    • [PMID: 21489974 DOI: 10.1093/ rheumatology/ker116]
    • Yang J, Yang X, Zou H, Chu Y, Li M. Recovery of the immune balance between Th17 and regulatory T cells as a treatment for systemic lupus erythematosus. Rheumatology (Oxford) 2011; 50: 1366-1372 [PMID: 21489974 DOI: 10.1093/ rheumatology/ker116]
    • (2011) Rheumatology (Oxford) , vol.50 , pp. 1366-1372
    • Yang, J.1    Yang, X.2    Zou, H.3    Chu, Y.4    Li, M.5
  • 35
    • 77954423599 scopus 로고    scopus 로고
    • Nucleoside analogue can improve the longterm prognosis of patients with hepatitis B virus infectionassociated acute on chronic liver failure
    • [PMID: 20512414 DOI: 10.1007/s10620-010-1257-7]
    • Cui YL, Yan F, Wang YB, Song XQ, Liu L, Lei XZ, Zheng MH, Tang H, Feng P. Nucleoside analogue can improve the longterm prognosis of patients with hepatitis B virus infectionassociated acute on chronic liver failure. Dig Dis Sci 2010; 55: 2373-2380 [PMID: 20512414 DOI: 10.1007/s10620-010-1257-7]
    • (2010) Dig Dis Sci , vol.55 , pp. 2373-2380
    • Cui, Y.L.1    Yan, F.2    Wang, Y.B.3    Song, X.Q.4    Liu, L.5    Lei, X.Z.6    Zheng, M.H.7    Tang, H.8    Feng, P.9
  • 36
    • 78249257780 scopus 로고    scopus 로고
    • Decreased ratio of Treg cells to Th17 cells correlates with HBV DNA suppression in chronic hepatitis B patients undergoing entecavir treatment
    • [PMID: 21079784 DOI: 10.1371/journal. pone.0013869]
    • Zhang JY, Song CH, Shi F, Zhang Z, Fu JL, Wang FS. Decreased ratio of Treg cells to Th17 cells correlates with HBV DNA suppression in chronic hepatitis B patients undergoing entecavir treatment. PLoS One 2010; 5: e13869 [PMID: 21079784 DOI: 10.1371/journal. pone.0013869]
    • (2010) PLoS One , vol.5
    • Zhang, J.Y.1    Song, C.H.2    Shi, F.3    Zhang, Z.4    Fu, J.L.5    Wang, F.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.