Inhibition of mitochondrial respiratory chain is involved in triptolide-induced liver injury

Fitoterapia

Volumn 82, Issue 8, 2011, Pages 1241-1248

  Fu, Qiang ^a   Huang, Xiao ^a   Shu, Bin ^b   Xue, Mei ^a   Zhang, Pinghu ^a   Wang, Tao ^a   Liu, Li ^c   Jiang, Zhenzhou ^a   Zhang, Luyong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NANJING TECH UNIVERSITY   (China)

^c YANGZHOU UNIVERSITY   (China)

Author keywords

Hyperlactacidemia; Liver injury; Microvesicular steatosis; Mitochondria; Triptolide

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; GLUTATHIONE; LACTIC ACID; PYRUVIC ACID; TRIPTOLIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FATTY ACID OXIDATION; FEMALE; HUMAN; HUMAN CELL; HYPERLACTATEMIA; IN VITRO STUDY; IN VIVO STUDY; LIVER INJURY; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN; STEATOSIS;

ANIMALS; CELL RESPIRATION; DITERPENES; DRUG-INDUCED LIVER INJURY; EPOXY COMPOUNDS; FATTY LIVER; FEMALE; LACTIC ACID; LIVER; MITOCHONDRIAL MEMBRANES; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHENANTHRENES; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; TRIPTERYGIUM;

TRIPTERYGIUM WILFORDII;

EID: 80054908941     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2011.08.019     Document Type: Article

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