Induction of lung cancer cell apoptosis through a p53 pathway by [6]-shogaol and its cysteine-conjugated metabolite M2

Journal of Agricultural and Food Chemistry

Volumn 62, Issue 6, 2014, Pages 1352-1362

  Warin, Renaud F ^a   Chen, Huadong ^a   Soroka, Dominique N ^a   Zhu, Yingdong ^a   Sang, Shengmin ^a  

^a NORTH CAROLINA A AND T STATE UNIVERSITY   (United States)

Author keywords

6 shogaol; apoptosis; cysteine conjugated metabolite; lung cancer; xenograft

Indexed keywords

AMINO ACIDS; BIOLOGICAL MATERIALS; BIOLOGICAL ORGANS; BIOMOLECULES; CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CYTOLOGY; DISEASES; METABOLITES; MITOCHONDRIA; TOXICITY; TUMORS;

ANTI-CANCER MECHANISM; ANTICANCER ACTIVITIES; APOPTOTIC PATHWAYS; CONJUGATED METABOLITES; HUMAN LUNG CANCER CELL LINE; LUNG CANCER; XENOGRAFT; [6]-SHOGAOL;

CELLS;

ANIMALIA; MUS MUSCULUS; ZINGIBER; ZINGIBER OFFICINALE;

ANTINEOPLASTIC AGENT; CATECHOL DERIVATIVE; CYSTEINE; DRUG DERIVATIVE; GLUTATHIONE; PROTEIN P53; SHOGAOL;

ANIMAL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; DRUG EFFECT; DRUG SCREENING; HUMAN; LUNG TUMOR; METABOLISM; MOUSE; NUDE MOUSE; OXIDATIVE STRESS; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CATECHOLS; CELL LINE, TUMOR; CELL PROLIFERATION; CYSTEINE; GLUTATHIONE; HUMANS; LUNG NEOPLASMS; MICE; MICE, NUDE; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84894198002     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf405573e     Document Type: Article

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