Proteomic survey reveals altered energetic patterns and metabolic failure prior to retinal degeneration

Journal of Neuroscience

Volumn 34, Issue 8, 2014, Pages 2797-2812

  Griciuc, Ana ^a,e   Roux, Michel J ^b   Merl, Juliane ^a   Giangrande, Angela ^b   Hauck, Stefanie M ^a   Aron, Liviu ^c   Ueffing, Marius ^a,d  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF TÜBINGEN   (Germany)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Metabolism; Mitochondria; MTOR; Proteomics; Retinitis pigmentosa; Rhodopsin

Indexed keywords

METABOLISM; MITOCHONDRIA; MTOR; PROTEOMICS; RETINITIS PIGMENTOSA; RHODOPSIN;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOTTING, WESTERN; CASPASE 9; COLORING AGENTS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ELECTRORETINOGRAPHY; ENDOPLASMIC RETICULUM STRESS; ENDOPLASMIC RETICULUM-ASSOCIATED DEGRADATION; ENERGY METABOLISM; MASS SPECTROMETRY; MICROSCOPY, ELECTRON; MITOCHONDRIA; MUTATION; OXIDATIVE STRESS; PROTEIN FOLDING; PROTEIN HYDROLYSATES; PROTEOMICS; RETINAL DEGENERATION; RHODOPSIN; SIGNAL TRANSDUCTION; TOLONIUM CHLORIDE; TOR SERINE-THREONINE KINASES;

EID: 84894046055     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2982-13.2014     Document Type: Article

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