FGF2-induced Ras-MAPK signalling maintains lymphatic endothelial cell identity by upregulating endothelial-cell-specific gene expression and suppressing TGFβ signalling through Smad2

Journal of Cell Science

Volumn 127, Issue 4, 2014, Pages 845-857

  Ichise, Taeko ^a   Yoshida, Nobuaki ^a   Ichise, Hirotake ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Endothelial mesenchymal transition; FGF2; Lymphatic endothelial cell; MAPK; Ras; Smad

Indexed keywords

ENDOTHELIAL-MESENCHYMAL TRANSITION; FGF2; LYMPHATIC ENDOTHELIAL CELL; MAPK; RAS; SMAD;

ANIMALS; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; ENDOTHELIAL CELLS; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION; LYMPHATIC VESSELS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, TRANSGENIC; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RAS PROTEINS; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84894045978     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.137836     Document Type: Article

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