Blocking Fibroblast Growth Factor receptor signaling inhibits tumor growth, lymphangiogenesis, and metastasis

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Larrieu Lahargue, Frédéric ^a,b,c,e   Welm, Alana L ^c   Bouchecareilh, Marion ^a,b   Alitalo, Kari ^d   Li, Dean Y ^c   Bikfalvi, Andreas ^a,b   Auguste, Patrick ^a,b  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b INSERM U 1029   (France)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^e Bordeaux Segalen University   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1 TERT BUTYL 3 [6 (3,5 DIMETHOXYPHENYL) 2 (4 DIETHYLAMINOBUTYLAMINO)PYRIDO[2,3 D]PYRIMIDIN 7 YL]UREA; ALPHA INTEGRIN; ALPHA9 INTEGRIN; CYCLOOXYGENASE 2; FIBROBLAST GROWTH FACTOR RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NETRIN 1; PD 173034; PODOPLANIN; UNCLASSIFIED DRUG; VASCULOTROPIN C; VASCULOTROPIN RECEPTOR 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; BREAST CARCINOMA; CANCER INHIBITION; CANCER SURVIVAL; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; EXPERIMENTAL MOUSE; IN VITRO STUDY; IN VIVO STUDY; LYMPHANGIOGENESIS; METASTASIS INHIBITION; MOUSE; NONHUMAN; OVERALL SURVIVAL; PARACRINE SIGNALING; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLOOXYGENASE 2; FEMALE; LYMPHANGIOGENESIS; LYMPHATIC METASTASIS; MAMMARY NEOPLASMS, ANIMAL; MICE; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; NERVE GROWTH FACTORS; RECEPTORS, FIBROBLAST GROWTH FACTOR; TUMOR SUPPRESSOR PROTEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3;

EID: 84862703800     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039540     Document Type: Article

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