-
1
-
-
34249689753
-
Molecular regulation of angiogenesis and lymphangiogenesis
-
Adams RH, Alitalo K. Molecular regulation of angiogenesis and lymphangiogenesis. Nat Rev Mol Cell Biol 2007; 8:464-478.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 464-478
-
-
Adams, R.H.1
Alitalo, K.2
-
2
-
-
30744432619
-
Endothelial cells and VEGF in vascular development
-
Coultas L, Chawengsaksophak K, Rossant J. Endothelial cells and VEGF in vascular development. Nature 2005; 438:937-945.
-
(2005)
Nature
, vol.438
, pp. 937-945
-
-
Coultas, L.1
Chawengsaksophak, K.2
Rossant, J.3
-
3
-
-
59649110012
-
Transcriptional control of endothelial cell development
-
De Val S, Black BL. Transcriptional control of endothelial cell development. Dev Cell 2009; 16:180-195.
-
(2009)
Dev Cell
, vol.16
, pp. 180-195
-
-
De Val, S.1
Black, B.L.2
-
4
-
-
0033578853
-
Prox1 function is required for the development of the murine lymphatic system
-
Wigle JT, Oliver G. Prox1 function is required for the development of the murine lymphatic system. Cell 1999; 98:769-778.
-
(1999)
Cell
, vol.98
, pp. 769-778
-
-
Wigle, J.T.1
Oliver, G.2
-
5
-
-
0036208217
-
The rediscovery of the lymphatic system: Old and new insights into the development and biological function of the lymphatic vasculature
-
Oliver G, Detmar M. The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature. Genes Dev 2002; 16:773-783.
-
(2002)
Genes Dev
, vol.16
, pp. 773-783
-
-
Oliver, G.1
Detmar, M.2
-
6
-
-
57349142376
-
Sox18 induces development of the lymphatic vasculature in mice
-
Francois M, Caprini A, Hosking B, et al. Sox18 induces development of the lymphatic vasculature in mice. Nature 2008; 456:643-647.
-
(2008)
Nature
, vol.456
, pp. 643-647
-
-
Francois, M.1
Caprini, A.2
Hosking, B.3
-
9
-
-
0031011529
-
Proteolytic processing regulates receptor specifcity and activity of VEGF-C
-
Joukov V, Sorsa T, Kumar V, et al. Proteolytic processing regulates receptor specifcity and activity of VEGF-C. EMBO J 1997; 16:3898-3911.
-
(1997)
EMBO J
, vol.16
, pp. 3898-3911
-
-
Joukov, V.1
Sorsa, T.2
Kumar, V.3
-
10
-
-
0033527634
-
Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers
-
Stacker SA, Stenvers K, Caesar C, et al. Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers. J Biol Chem 1999; 274:32127-32136.
-
(1999)
J Biol Chem
, vol.274
, pp. 32127-32136
-
-
Stacker, S.A.1
Stenvers, K.2
Caesar, C.3
-
11
-
-
33750712397
-
MAPping out arteries and veins
-
Lamont RE, Childs S. MAPping out arteries and veins. Sci STKE 2006; 2006:pe39.
-
(2006)
Sci STKE
-
-
Lamont, R.E.1
Childs, S.2
-
12
-
-
0035122695
-
Inhibition of lymp-hangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3
-
Makinen T, Jussila L, Veikkola T, et al. Inhibition of lymp-hangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. Nat Med 2001; 7:199-205.
-
(2001)
Nat Med
, vol.7
, pp. 199-205
-
-
Makinen, T.1
Jussila, L.2
Veikkola, T.3
-
13
-
-
0034041161
-
Missense mutations interfere with VEGFR-3 signalling in primary lym-phoedema
-
Karkkainen MJ, Ferrell RE, Lawrence EC, et al. Missense mutations interfere with VEGFR-3 signalling in primary lym-phoedema. Nat Genet 2000; 25:153-159.
-
(2000)
Nat Genet
, vol.25
, pp. 153-159
-
-
Karkkainen, M.J.1
Ferrell, R.E.2
Lawrence, E.C.3
-
14
-
-
0037024472
-
Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling
-
He Y, Kozaki K, Karpanen T, et al. Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling. J Natl Cancer Inst 2002; 94:819-825.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 819-825
-
-
He, Y.1
Kozaki, K.2
Karpanen, T.3
-
15
-
-
0028938746
-
Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development
-
Kaipainen A, Korhonen J, Mustonen T, et al. Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc Natl Acad Sci USA 1995; 92:3566-3570.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3566-3570
-
-
Kaipainen, A.1
Korhonen, J.2
Mustonen, T.3
-
16
-
-
0032933883
-
VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer
-
Valtola R, Salven P, Heikkila P, et al. VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer. Am J Pathol 1999; 154:1381-1390.
-
(1999)
Am J Pathol
, vol.154
, pp. 1381-1390
-
-
Valtola, R.1
Salven, P.2
Heikkila, P.3
-
17
-
-
0036897107
-
Induction of vascular endothelial growth factor receptor-3 expression on tumor microvasculature as a new progression marker in human cutaneous melanoma
-
Clarijs R, Schalkwijk L, Hofmann UB, Ruiter DJ, de Waal RM. Induction of vascular endothelial growth factor receptor-3 expression on tumor microvasculature as a new progression marker in human cutaneous melanoma. Cancer Res 2002; 62:7059-7065.
-
(2002)
Cancer Res
, vol.62
, pp. 7059-7065
-
-
Clarijs, R.1
Schalkwijk, L.2
Hofmann, U.B.3
Ruiter, D.J.4
De Waal, R.M.5
-
18
-
-
18544393909
-
Involvement of vascular endothelial growth factor receptor-3 in maintenance of integrity of endothelial cell lining during tumor angiogenesis
-
Kubo H, Fujiwara T, Jussila L, et al. Involvement of vascular endothelial growth factor receptor-3 in maintenance of integrity of endothelial cell lining during tumor angiogenesis. Blood 2000; 96:546-553.
-
(2000)
Blood
, vol.96
, pp. 546-553
-
-
Kubo, H.1
Fujiwara, T.2
Jussila, L.3
-
19
-
-
48349129069
-
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
-
Tammela T, Zarkada G, Wallgard E, et al. Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature 2008; 454:656-660.
-
(2008)
Nature
, vol.454
, pp. 656-660
-
-
Tammela, T.1
Zarkada, G.2
Wallgard, E.3
-
20
-
-
0032582502
-
Cardiovascular failure in mouse embryos deficient in VEGF receptor-3
-
Dumont DJ, Jussila L, Taipale J, et al. Cardiovascular failure in mouse embryos deficient in VEGF receptor-3. Science 1998; 282:946-949.
-
(1998)
Science
, vol.282
, pp. 946-949
-
-
Dumont, D.J.1
Jussila, L.2
Taipale, J.3
-
21
-
-
0034554844
-
VEGF-C signaling pathways through VEGFR-2 and VEGFR-3 in vasculoangio-genesis and hematopoiesis
-
Hamada K, Oike Y, Takakura N, et al. VEGF-C signaling pathways through VEGFR-2 and VEGFR-3 in vasculoangio-genesis and hematopoiesis. Blood 2000; 96:3793-3800.
-
(2000)
Blood
, vol.96
, pp. 3793-3800
-
-
Hamada, K.1
Oike, Y.2
Takakura, N.3
-
22
-
-
47949083776
-
Deletion of vascular endothelial growth factor (VEGF-C) and VEGF-D is not equivalent to VEGFR-3-null in mouse embryos
-
Haiko P, Makinen T, Keskitalo S, et al. Deletion of vascular endothelial growth factor (VEGF-C) and VEGF-D is not equivalent to VEGFR-3-null in mouse embryos. Mol Cell Biol 2008; 28:4843-4850.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4843-4850
-
-
Haiko, P.1
Makinen, T.2
Keskitalo, S.3
-
23
-
-
0030008349
-
Effcient in vivo manipulation of mouse genomic sequences at the zygote stage
-
Lakso M, Pichel JG, Gorman JR, et al. Effcient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc Natl Acad Sci USA 1996; 93:5860-5865.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5860-5865
-
-
Lakso, M.1
Pichel, J.G.2
Gorman, J.R.3
-
24
-
-
0033593793
-
LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specifc receptor for hy-aluronan
-
Banerji S, Ni J, Wang SX, et al. LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specifc receptor for hy-aluronan. J Cell Biol 1999; 144:789-801.
-
(1999)
J Cell Biol
, vol.144
, pp. 789-801
-
-
Banerji, S.1
Ni, J.2
Wang, S.X.3
-
25
-
-
46949088172
-
Expression of the hyaluro-nan receptor LYVE-1 is not restricted to the lymphatic vascu-lature;LYVE-1 is also expressed on embryonic blood vessels
-
Gordon EJ, Gale NW, Harvey NL. Expression of the hyaluro-nan receptor LYVE-1 is not restricted to the lymphatic vascu-lature; LYVE-1 is also expressed on embryonic blood vessels. Dev Dyn 2008; 237:1901-1909.
-
(2008)
Dev Dyn
, vol.237
, pp. 1901-1909
-
-
Gordon, E.J.1
Gale, N.W.2
Harvey, N.L.3
-
27
-
-
10044287078
-
Extracellular matrix regulates endothelial functions through interaction of VEGFR-3 and integrin alpha5beta1
-
Zhang X, Groopman JE, Wang JF. Extracellular matrix regulates endothelial functions through interaction of VEGFR-3 and integrin alpha5beta1. J Cell Physiol 2005; 202:205-214.
-
(2005)
J Cell Physiol
, vol.202
, pp. 205-214
-
-
Zhang, X.1
Groopman, J.E.2
Wang, J.F.3
-
28
-
-
33746503288
-
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
-
Karpanen T, Heckman CA, Keskitalo S, et al. Functional interaction of VEGF-C and VEGF-D with neuropilin receptors. FASEB J 2006; 20:1462-1472.
-
(2006)
FASEB J
, vol.20
, pp. 1462-1472
-
-
Karpanen, T.1
Heckman, C.A.2
Keskitalo, S.3
-
29
-
-
77951498501
-
VEGF receptor 2/-3 het-erodimers detected in situ by proximity ligation on angiogenic sprouts
-
Nilsson I, Bahram F, Li X, et al. VEGF receptor 2/-3 het-erodimers detected in situ by proximity ligation on angiogenic sprouts. EMBO J 2010; 29:1377-1388.
-
(2010)
EMBO J
, vol.29
, pp. 1377-1388
-
-
Nilsson, I.1
Bahram, F.2
Li, X.3
-
30
-
-
9144236286
-
Vascular endothelial growth factor C is required for sprouting of the frst lymphatic vessels from embryonic veins
-
Karkkainen MJ, Haiko P, Sainio K, et al. Vascular endothelial growth factor C is required for sprouting of the frst lymphatic vessels from embryonic veins. Nat Immunol 2004; 5:74-80.
-
(2004)
Nat Immunol
, vol.5
, pp. 74-80
-
-
Karkkainen, M.J.1
Haiko, P.2
Sainio, K.3
-
31
-
-
21144437844
-
Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels
-
He Y, Rajantie I, Pajusola K, et al. Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels. Cancer Res 2005; 65:4739-4746.
-
(2005)
Cancer Res
, vol.65
, pp. 4739-4746
-
-
He, Y.1
Rajantie, I.2
Pajusola, K.3
-
32
-
-
0032482978
-
Flt-1 lacking the tyrosine kinase domain is suffcient for normal development and angiogenesis in mice
-
Hiratsuka S, Minowa O, Kuno J, Noda T, Shibuya M. Flt-1 lacking the tyrosine kinase domain is suffcient for normal development and angiogenesis in mice. Proc Natl Acad Sci USA 1998; 95:9349-9354.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9349-9354
-
-
Hiratsuka, S.1
Minowa, O.2
Kuno, J.3
Noda, T.4
Shibuya, M.5
-
33
-
-
17044458971
-
Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic en-dothelial cells regulates tyrosine phosphorylation sites
-
Dixelius J, Makinen T, Wirzenius M, et al. Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic en-dothelial cells regulates tyrosine phosphorylation sites. J Biol Chem 2003; 278:40973-40979.
-
(2003)
J Biol Chem
, vol.278
, pp. 40973-40979
-
-
Dixelius, J.1
Makinen, T.2
Wirzenius, M.3
-
34
-
-
0035834793
-
Stimulation of beta 1 inte-grin induces tyrosine phosphorylation of vascular endothelial growth factor receptor-3 and modulates cell migration
-
Wang JF, Zhang XF, Groopman JE. Stimulation of beta 1 inte-grin induces tyrosine phosphorylation of vascular endothelial growth factor receptor-3 and modulates cell migration. J Biol Chem 2001; 276:41950-41957.
-
(2001)
J Biol Chem
, vol.276
, pp. 41950-41957
-
-
Wang, J.F.1
Zhang, X.F.2
Groopman, J.E.3
-
35
-
-
77954214925
-
Endothelial cell adhesion to the extracellular matrix induces c-Src-dependent VEGFR-3 phosphorylation without the activation of the receptor intrinsic kinase activity
-
Galvagni F, Pennacchini S, Salameh A, et al. Endothelial cell adhesion to the extracellular matrix induces c-Src-dependent VEGFR-3 phosphorylation without the activation of the receptor intrinsic kinase activity. Circ Res 2010; 106:1839-1848.
-
(2010)
Circ Res
, vol.106
, pp. 1839-1848
-
-
Galvagni, F.1
Pennacchini, S.2
Salameh, A.3
-
36
-
-
75749124699
-
Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3
-
Xu Y, Yuan L, Mak J, et al. Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3. J Cell Biol 2010; 188:115-130.
-
(2010)
J Cell Biol
, vol.188
, pp. 115-130
-
-
Xu, Y.1
Yuan, L.2
Mak, J.3
-
37
-
-
0037352031
-
A highly effcient recom-bineering-based method for generating conditional knockout mutations
-
Liu P, Jenkins NA, Copeland NG. A highly effcient recom-bineering-based method for generating conditional knockout mutations. Genome Res 2003; 13:476-484.
-
(2003)
Genome Res
, vol.13
, pp. 476-484
-
-
Liu, P.1
Jenkins, N.A.2
Copeland, N.G.3
-
38
-
-
0027321548
-
Derivation of completely cell culture-derived mice from early-passage embryonic stem cells
-
Nagy A, Rossant J, Nagy R, Abramow-Newerly W, Roder JC. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci USA 1993; 90:8424-8428.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8424-8428
-
-
Nagy, A.1
Rossant, J.2
Nagy, R.3
Abramow-Newerly, W.4
Roder, J.C.5
-
40
-
-
0035266283
-
Vascular en-dothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth
-
Karpanen T, Egeblad M, Karkkainen MJ, et al. Vascular en-dothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth. Cancer Res 2001; 61:1786-1790.
-
(2001)
Cancer Res
, vol.61
, pp. 1786-1790
-
-
Karpanen, T.1
Egeblad, M.2
Karkkainen, M.J.3
-
41
-
-
34347217526
-
A protocol for isolation and culture of human umbilical vein endothe-lial cells
-
Baudin B, Bruneel A, Bosselut N, Vaubourdolle M. A protocol for isolation and culture of human umbilical vein endothe-lial cells. Nat Protocol 2007; 2:481-485.
-
(2007)
Nat Protocol
, vol.2
, pp. 481-485
-
-
Baudin, B.1
Bruneel, A.2
Bosselut, N.3
Vaubourdolle, M.4
-
42
-
-
0035355472
-
A single au-tophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells
-
Takahashi T, Yamaguchi S, Chida K, Shibuya M. A single au-tophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells. EMBO J 2001; 20:2768-2778.
-
(2001)
EMBO J
, vol.20
, pp. 2768-2778
-
-
Takahashi, T.1
Yamaguchi, S.2
Chida, K.3
Shibuya, M.4
-
43
-
-
34249666193
-
Distinct architecture of lymphatic vessels induced by chimeric vascular endothelial growth factor-C/vascular endothelial growth factor heparin-binding domain fusion proteins
-
Tammela T, He Y, Lyytikka J, et al. Distinct architecture of lymphatic vessels induced by chimeric vascular endothelial growth factor-C/vascular endothelial growth factor heparin-binding domain fusion proteins. Circ Res 2007; 100:1468-1475.
-
(2007)
Circ Res
, vol.100
, pp. 1468-1475
-
-
Tammela, T.1
He, Y.2
Lyytikka, J.3
|