In vitro Inactivation of Latent HSV by Targeted Mutagenesis Using an HSV-specific Homing Endonuclease

Molecular Therapy Nucleic Acids

Volumn 3, Issue , 2014, Pages

  Aubert, Martine ^a   Boyle, Nicole M ^a   Stone, Daniel ^a   Stensland, Laurence ^b   Huang, Meei Li ^b   Magaret, Amalia S ^a,b   Galetto, Roman ^c   Rawlings, David J ^d   Scharenberg, Andrew M ^c,e   Jerome, Keith R ^a,b  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c Arvid Wallgrens Backe 20   (France)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^e SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 DEAZANEPLANOCIN A; ACICLOVIR; ALPHA INTERFERON; BUTYRIC ACID; ENDONUCLEASE; EXONUCLEASE TREX2; HISTONE DEACETYLASE INHIBITOR; HOMING ENDONUCLEASE; PARVOVIRUS VECTOR; SPLEEN EXONUCLEASE; TRICHOSTATIN A; UNCLASSIFIED DRUG; VALPROIC ACID; VIRUS PROTEIN; VP5 PROTEIN; EXONUCLEASE; VIRION PROTEIN 5;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ARTICLE; CHROMATIN STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EXPOSURE; FIBROBLAST; GENE EXPRESSION; GENE FREQUENCY; GENE SEQUENCE; GENE TARGETING; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IN VITRO STUDY; MEDIATOR; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; VIRAL GENE DELIVERY SYSTEM; VIROGENESIS; VIRUS GENOME; VIRUS INACTIVATION; VIRUS LATENCY; VIRUS REACTIVATION; VIRUS STRAIN; CHRONIC DISEASE; DNA MODIFICATION; DOUBLE STRANDED DNA BREAK; EPIGENETICS; GENE DISRUPTION; GENETIC CODE; GENOME; HERPES SIMPLEX; IMMEDIATE EARLY GENE; LATENT PERIOD; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENE; VIRUS GENE; VIRUS INFECTION;

EID: 84893869053     PISSN: None     EISSN: 21622531     Source Type: Journal    
DOI: 10.1038/mtna.2013.75     Document Type: Article

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