Chromatin structure of two genomic sites for targeted transgene integration in induced pluripotent stem cells and hematopoietic stem cells

Gene Therapy

Volumn 20, Issue 2, 2013, Pages 201-214

  Van Rensburg, R ^a   Beyer, I ^a   Yao, X Y ^a   Wang, H ^a   Denisenko, O ^b   Li, Z Y ^a   Russell, D W ^c   Miller, D G ^a   Gregory, P ^d   Holmes, M ^d   Bomsztyk, K ^b   Lieber, A ^a,c  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d SANGAMO BIOSCIENCES INC   (United States)

Author keywords

Chromatin; iPS cells; Targeted integration; Zinc finger nucleases

Indexed keywords

ADENOVIRUS VECTOR; ENDONUCLEASE;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA MODIFICATION; ENZYME ACTIVITY; GENE EXPRESSION; GENE INSERTION; GENE LOCUS; GENE TRANSFER; HEMATOPOIETIC CELL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; TRANSGENE INTEGRATION;

ANTIGENS, CD34; CHROMATIN; DEPENDOVIRUS; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; GENE TARGETING; GENETIC LOCI; GENETIC VECTORS; GENOME, HUMAN; HEMATOPOIETIC STEM CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; PROTEIN PHOSPHATASE 1; RECEPTORS, CCR5; TRANSCRIPTION, GENETIC; TRANSGENES; VIRAL PROTEINS; ZINC FINGERS;

IPS;

EID: 84873570368     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2012.25     Document Type: Article

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