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Volumn 72, Issue 7, 1998, Pages 5343-5350

The latent herpes simplex virus type 1 genome copy number in individual neurons is virus strain specific and correlates with reactivation

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; VIRUS ANTIGEN;

EID: 0031746198     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.7.5343-5350.1998     Document Type: Article
Times cited : (166)

References (40)
  • 1
    • 0029912982 scopus 로고    scopus 로고
    • A 348-base-pair region in the latency-associated transcript facilitates herpes simplex virus type 1 reactivation
    • Bloom, D. C., J. M. Hill, G. Devi-Rao, E. K. Wagner, L. T. Feldman, and J. G. Stevens. 1996. A 348-base-pair region in the latency-associated transcript facilitates herpes simplex virus type 1 reactivation. J. Virol. 70:2449-2459.
    • (1996) J. Virol. , vol.70 , pp. 2449-2459
    • Bloom, D.C.1    Hill, J.M.2    Devi-Rao, G.3    Wagner, E.K.4    Feldman, L.T.5    Stevens, J.G.6
  • 2
    • 0027361738 scopus 로고
    • The herpes simplex virus type 1 regulatory protein ICP0 enhances virus replication during acute infection and reactivation from latency
    • Cai, W., T. L. Astor, L. M. Liptak, C. Cho, D. M. Coen, and P. A. Schaffer. 1993. The herpes simplex virus type 1 regulatory protein ICP0 enhances virus replication during acute infection and reactivation from latency. J. Virol. 67:7501-7512.
    • (1993) J. Virol. , vol.67 , pp. 7501-7512
    • Cai, W.1    Astor, T.L.2    Liptak, L.M.3    Cho, C.4    Coen, D.M.5    Schaffer, P.A.6
  • 3
    • 0021355416 scopus 로고
    • Relation of target encounter and neuronal death to nerve growth factor responsiveness in the developing mouse trigeminal ganglion
    • Davies, A., and A. Lumsden. 1984. Relation of target encounter and neuronal death to nerve growth factor responsiveness in the developing mouse trigeminal ganglion. J. Comp. Neurol. 223:124-137.
    • (1984) J. Comp. Neurol. , vol.223 , pp. 124-137
    • Davies, A.1    Lumsden, A.2
  • 4
    • 0028903361 scopus 로고
    • In vivo deletion analysis of the herpes simplex virus type 1 latency-associated transcript promoter
    • Dobson, A. T., T. P. Margolis, W. A. Gomes, and L. T. Feldman. 1995. In vivo deletion analysis of the herpes simplex virus type 1 latency-associated transcript promoter. J. Virol. 69:2264-2270.
    • (1995) J. Virol. , vol.69 , pp. 2264-2270
    • Dobson, A.T.1    Margolis, T.P.2    Gomes, W.A.3    Feldman, L.T.4
  • 5
    • 0028789833 scopus 로고
    • Development and application of herpes simplex virus vectors for human gene therapy
    • Glorioso, J. C., N. A. DeLuca, and D. J. Fink. 1995. Development and application of herpes simplex virus vectors for human gene therapy. Annu. Rev. Microbiol. 49:675-710.
    • (1995) Annu. Rev. Microbiol. , vol.49 , pp. 675-710
    • Glorioso, J.C.1    DeLuca, N.A.2    Fink, D.J.3
  • 6
    • 0029084896 scopus 로고
    • The proportion of trigeminal ganglionic neurons expressing herpes simplex virus type 1 latency-associated transcripts correlates to reactivation in the New Zealand rabbit ocular model
    • Gordon, Y. J., E. G. Romanowski, T. Araullo-Cruz, and P. R. Kinchington. 1995. The proportion of trigeminal ganglionic neurons expressing herpes simplex virus type 1 latency-associated transcripts correlates to reactivation in the New Zealand rabbit ocular model. Graefe's Arch. Clin. Exp. Ophthalmol. 233:649-654.
    • (1995) Graefe's Arch. Clin. Exp. Ophthalmol. , vol.233 , pp. 649-654
    • Gordon, Y.J.1    Romanowski, E.G.2    Araullo-Cruz, T.3    Kinchington, P.R.4
  • 7
    • 0026026623 scopus 로고
    • Glycoprotein C of herpes simplex virus type 1 plays a principal role in the adsorption of virus to cells and in infectivity
    • Herold, B. C., D. WuDunn, N. Soltys, and P. G. Spear. 1991. Glycoprotein C of herpes simplex virus type 1 plays a principal role in the adsorption of virus to cells and in infectivity. J. Virol. 65:1090-1098.
    • (1991) J. Virol. , vol.65 , pp. 1090-1098
    • Herold, B.C.1    WuDunn, D.2    Soltys, N.3    Spear, P.G.4
  • 8
    • 0030808931 scopus 로고    scopus 로고
    • A 437-base-pair deletion at the beginning of the latency-associated transcript promoter significantly reduced adrenergically induced herpes simplex virus type 1 ocular reactivation in latently infected rabbits
    • Hill, J. M., H. H. Garza, Jr., Y. H. Su, R. Meegalla, L. A. Hanna, J. M. Loutsch, H. W. Thompson, E. D. Varnell, D. C. Bloom, and T. M. Block. 1997. A 437-base-pair deletion at the beginning of the latency-associated transcript promoter significantly reduced adrenergically induced herpes simplex virus type 1 ocular reactivation in latently infected rabbits. J. Virol. 71:6555-6559.
    • (1997) J. Virol. , vol.71 , pp. 6555-6559
    • Hill, J.M.1    Garza Jr., H.H.2    Su, Y.H.3    Meegalla, R.4    Hanna, L.A.5    Loutsch, J.M.6    Thompson, H.W.7    Varnell, E.D.8    Bloom, D.C.9    Block, T.M.10
  • 9
    • 0029794593 scopus 로고    scopus 로고
    • In vivo epinephrine reactivation of ocular herpes simplex virus type 1 in the rabbit is correlated to a 370-base-pair region located between the promoter and the 5′ end of the 2.0-kilobase latency-associated transcript
    • Hill, J. M., J. B. Maggioncalda, H. H. Garza, Jr., Y. H. Su, N. W. Fraser, and T. M. Block. 1996. In vivo epinephrine reactivation of ocular herpes simplex virus type 1 in the rabbit is correlated to a 370-base-pair region located between the promoter and the 5′ end of the 2.0-kilobase latency-associated transcript. J. Virol. 70:7270-7274.
    • (1996) J. Virol. , vol.70 , pp. 7270-7274
    • Hill, J.M.1    Maggioncalda, J.B.2    Garza Jr., H.H.3    Su, Y.H.4    Fraser, N.W.5    Block, T.M.6
  • 10
    • 0025004160 scopus 로고
    • Molecular and biological characterization of a herpes simplex virus type 1 (HSV-1) neuroinvasiveness gene
    • Izumi, K. M., and J. G. Stevens. 1990. Molecular and biological characterization of a herpes simplex virus type 1 (HSV-1) neuroinvasiveness gene. J. Exp. Med. 172:487-496.
    • (1990) J. Exp. Med. , vol.172 , pp. 487-496
    • Izumi, K.M.1    Stevens, J.G.2
  • 11
  • 12
    • 0025145916 scopus 로고
    • Quantitative polymerase chain reaction analysis of herpes simplex virus DNA in ganglia of mice infected with replication-incompetent mutants
    • Katz, J. P., E. T. Bodin, and D. M. Coen. 1990. Quantitative polymerase chain reaction analysis of herpes simplex virus DNA in ganglia of mice infected with replication-incompetent mutants. J. Virol. 64:4288-4295.
    • (1990) J. Virol. , vol.64 , pp. 4288-4295
    • Katz, J.P.1    Bodin, E.T.2    Coen, D.M.3
  • 13
    • 0025083395 scopus 로고
    • Restricted expression of herpes simplex virus lytic genes during establishment of latent infection by thymidine kinase-negative mutant viruses
    • Kosz-Vnenchak, M., D. M. Coen, and D. M. Knipe. 1990. Restricted expression of herpes simplex virus lytic genes during establishment of latent infection by thymidine kinase-negative mutant viruses. J. Virol. 64:5396-5402.
    • (1990) J. Virol. , vol.64 , pp. 5396-5402
    • Kosz-Vnenchak, M.1    Coen, D.M.2    Knipe, D.M.3
  • 14
    • 0027184328 scopus 로고
    • Evidence for a novel regulatory pathway for herpes simplex virus gene expression in trigeminal ganglion neurons
    • Kosz-Vnenchak, M., J. Jacobson, D. M. Coen, and D. M. Knipe. 1993. Evidence for a novel regulatory pathway for herpes simplex virus gene expression in trigeminal ganglion neurons. J. Virol. 67:5383-5393.
    • (1993) J. Virol. , vol.67 , pp. 5383-5393
    • Kosz-Vnenchak, M.1    Jacobson, J.2    Coen, D.M.3    Knipe, D.M.4
  • 15
    • 0028833335 scopus 로고
    • Quantification of transcripts from the ICP4 and thymidine kinase genes in mouse ganglia latently infected with herpes simplex virus
    • Kramer, M. F., and D. M. Coen. 1995. Quantification of transcripts from the ICP4 and thymidine kinase genes in mouse ganglia latently infected with herpes simplex virus. J. Virol. 69:1389-1399.
    • (1995) J. Virol. , vol.69 , pp. 1389-1399
    • Kramer, M.F.1    Coen, D.M.2
  • 16
    • 0024537137 scopus 로고
    • Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency
    • Leib, D. A., D. M. Coen, C. L. Bogard, K. A. Hicks, D. R. Yager, D. M. Knipe, K. L. Tyler, and P. A. Schaffer. 1989. Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency. J. Virol. 63:759-768.
    • (1989) J. Virol. , vol.63 , pp. 759-768
    • Leib, D.A.1    Coen, D.M.2    Bogard, C.L.3    Hicks, K.A.4    Yager, D.R.5    Knipe, D.M.6    Tyler, K.L.7    Schaffer, P.A.8
  • 17
    • 0030860992 scopus 로고    scopus 로고
    • The latency-associated promoter of herpes simplex virus type 1 requires a region downstream of the transcription start site tor long-term expression during latency
    • Lokensgard, J. R., H. Berthomme, and L. T. Feldman. 1997. The latency-associated promoter of herpes simplex virus type 1 requires a region downstream of the transcription start site tor long-term expression during latency. J. Virol. 71:6714-6719.
    • (1997) J. Virol. , vol.71 , pp. 6714-6719
    • Lokensgard, J.R.1    Berthomme, H.2    Feldman, L.T.3
  • 18
    • 0030296293 scopus 로고    scopus 로고
    • Correlation between herpes simplex virus type 1 rate of reactivation from latent infection and the number of infected neurons in trigeminal ganglia
    • Maggioncalda, J., A. Mehta, Y. H. Su, N. W. Fraser, and T. M. Block. 1996. Correlation between herpes simplex virus type 1 rate of reactivation from latent infection and the number of infected neurons in trigeminal ganglia. Virology 225:72-81.
    • (1996) Virology , vol.225 , pp. 72-81
    • Maggioncalda, J.1    Mehta, A.2    Su, Y.H.3    Fraser, N.W.4    Block, T.M.5
  • 19
    • 0027440544 scopus 로고
    • Decreased reporter gene expression during latent infection with HSV LAT promoter constructs
    • Margolis, T. P., D. C. Bloom, A. T. Dobson, L. T. Feldman, and J. G. Stevens. 1993. Decreased reporter gene expression during latent infection with HSV LAT promoter constructs. Virology 197:585-592.
    • (1993) Virology , vol.197 , pp. 585-592
    • Margolis, T.P.1    Bloom, D.C.2    Dobson, A.T.3    Feldman, L.T.4    Stevens, J.G.5
  • 20
    • 0026333513 scopus 로고
    • Comparative sequence analysis of the long repeat regions and adjoining parts of the long unique regions in the genomes of herpes simplex viruses type-1 and type-2
    • McGeoch, D. J., C. Cunningham, G. Mcintyre, and A. Dolan. 1991. Comparative sequence analysis of the long repeat regions and adjoining parts of the long unique regions in the genomes of herpes simplex viruses type-1 and type-2. J. Gen. Virol. 72:3057-3075.
    • (1991) J. Gen. Virol. , vol.72 , pp. 3057-3075
    • McGeoch, D.J.1    Cunningham, C.2    Mcintyre, G.3    Dolan, A.4
  • 22
    • 0022354892 scopus 로고
    • Sequence determination and genetic content of the short unique region in the genome of herpes simplex virus type 1
    • McGeoch, D. J., A. Dolan, S. Donald, and F. J. Rixon. 1985. Sequence determination and genetic content of the short unique region in the genome of herpes simplex virus type 1. J. Mol. Biol. 181:1-13.
    • (1985) J. Mol. Biol. , vol.181 , pp. 1-13
    • McGeoch, D.J.1    Dolan, A.2    Donald, S.3    Rixon, F.J.4
  • 23
    • 0028796668 scopus 로고
    • In situ DNA PCR and RNA hybridization detection of herpes simplex virus sequences in trigeminal ganglia of latently infected mice
    • Mehta, A., J. Maggioncalda, O. Bagasra, S. Thikkavarapu, P. Saikumari, T. Valyi-Nagy, N. W. Fraser, and T. M. Block. 1995. In situ DNA PCR and RNA hybridization detection of herpes simplex virus sequences in trigeminal ganglia of latently infected mice. Virology 206:633-640.
    • (1995) Virology , vol.206 , pp. 633-640
    • Mehta, A.1    Maggioncalda, J.2    Bagasra, O.3    Thikkavarapu, S.4    Saikumari, P.5    Valyi-Nagy, T.6    Fraser, N.W.7    Block, T.M.8
  • 24
    • 0029655274 scopus 로고    scopus 로고
    • The region of the herpes simplex virus type 1 LAT gene that is colinear with the ICP34.5 gene is not involved in spontaneous reactivation
    • Perng, G. C., K. Chokephaibulkit, R. L. Thompson, N. M. Sawtell, S. M. Slanina, H. Ghiasi, A. B. Nesburn, and S. L. Wechsler. 1996. The region of the herpes simplex virus type 1 LAT gene that is colinear with the ICP34.5 gene is not involved in spontaneous reactivation. J. Virol. 70:282-291.
    • (1996) J. Virol. , vol.70 , pp. 282-291
    • Perng, G.C.1    Chokephaibulkit, K.2    Thompson, R.L.3    Sawtell, N.M.4    Slanina, S.M.5    Ghiasi, H.6    Nesburn, A.B.7    Wechsler, S.L.8
  • 25
    • 0027186444 scopus 로고
    • In vivo characterization of site-directed mutations in the promoter of the herpes simplex virus type 1 latency-associated transcripts
    • Rader, K. A., C. E. Ackland-Berglund, J. K. Miller, J. S. Pepose, and D. A. Leib. 1993. In vivo characterization of site-directed mutations in the promoter of the herpes simplex virus type 1 latency-associated transcripts. J. Gen. Virol. 74:1859-1869.
    • (1993) J. Gen. Virol. , vol.74 , pp. 1859-1869
    • Rader, K.A.1    Ackland-Berglund, C.E.2    Miller, J.K.3    Pepose, J.S.4    Leib, D.A.5
  • 26
    • 0028135457 scopus 로고
    • PCR-based analysis of herpes simplex virus type 1 latency in the rat trigeminal ganglion established with a ribonucleotide reductase-deficient mutant
    • Ramakrishnan, R., M. Levine, and D. J. Fink. 1994. PCR-based analysis of herpes simplex virus type 1 latency in the rat trigeminal ganglion established with a ribonucleotide reductase-deficient mutant. J. Virol. 68:7083-7091.
    • (1994) J. Virol. , vol.68 , pp. 7083-7091
    • Ramakrishnan, R.1    Levine, M.2    Fink, D.J.3
  • 27
    • 0028223319 scopus 로고
    • A herpes simplex virus 1 US11-expressing cell line is resistant to herpes simplex virus infection at a step in viral entry mediated by glycoprotein D
    • Roller, R. J., and B. Roizman. 1994. A herpes simplex virus 1 US11-expressing cell line is resistant to herpes simplex virus infection at a step in viral entry mediated by glycoprotein D. J. Virol. 68:2830-2839.
    • (1994) J. Virol. , vol.68 , pp. 2830-2839
    • Roller, R.J.1    Roizman, B.2
  • 28
    • 0030972161 scopus 로고    scopus 로고
    • Comprehensive quantification of herpes simplex virus latency at the single-cell level
    • Sawtell, N. M. 1997. Comprehensive quantification of herpes simplex virus latency at the single-cell level. J. Virol. 71:5423-5431.
    • (1997) J. Virol. , vol.71 , pp. 5423-5431
    • Sawtell, N.M.1
  • 29
    • 0024836467 scopus 로고
    • Cellular distribution of smooth muscle actins during mammalian embryogenesis: Expression of the a-vascular but not the g-enteric isoform in differentiated striated myocytes
    • Sawtell, N. M., and J. L. Lessard. 1989. Cellular distribution of smooth muscle actins during mammalian embryogenesis: expression of the a-vascular but not the g-enteric isoform in differentiated striated myocytes. J. Cell Biol. 109:2929-2937.
    • (1989) J. Cell Biol. , vol.109 , pp. 2929-2937
    • Sawtell, N.M.1    Lessard, J.L.2
  • 30
    • 0026608638 scopus 로고
    • Rapid in vivo reactivation of herpes simplex virus in latently infected murine ganglionic neurons after transient hyperthermia
    • Sawtell, N. M., and R. L. Thompson. 1992. Rapid in vivo reactivation of herpes simplex virus in latently infected murine ganglionic neurons after transient hyperthermia. J. Virol. 66:2150-2156.
    • (1992) J. Virol. , vol.66 , pp. 2150-2156
    • Sawtell, N.M.1    Thompson, R.L.2
  • 31
    • 0026583838 scopus 로고
    • Herpes simplex virus type 1 latency-associated transcription unit promotes anatomical site-dependent establishment and reactivation from latency
    • Sawtell, N. M., and R. L. Thompson. 1992. Herpes simplex virus type 1 latency-associated transcription unit promotes anatomical site-dependent establishment and reactivation from latency. J. Virol. 66:2157-2169.
    • (1992) J. Virol. , vol.66 , pp. 2157-2169
    • Sawtell, N.M.1    Thompson, R.L.2
  • 32
    • 2642675100 scopus 로고    scopus 로고
    • Sawtell, N. M., and R. L. Thompson. Unpublished data
    • Sawtell, N. M., and R. L. Thompson. Unpublished data.
  • 33
    • 0025689206 scopus 로고
    • Amplification by host cell factors of a sequence contained within the herpes simplex virus 1 genome
    • Sears, A., and E. B. Roizman. 1990. Amplification by host cell factors of a sequence contained within the herpes simplex virus 1 genome. Proc. Natl. Acad. Sci. USA 87:9441-9444.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9441-9444
    • Sears, A.1    Roizman, E.B.2
  • 34
    • 0028085575 scopus 로고
    • A structural and functional comparison of the latency-associated transcript promoters of herpes simplex virus type 1 strains KOS and McKrae
    • Strelow, L. I., K. A. Laycock, P. Y. Jun, K. A. Rader, R. H. Brady, J. K. Miller, J. S. Pepose, and D. A. Leib. 1994. A structural and functional comparison of the latency-associated transcript promoters of herpes simplex virus type 1 strains KOS and McKrae. J. Gen. Virol. 75:2475-2480.
    • (1994) J. Gen. Virol. , vol.75 , pp. 2475-2480
    • Strelow, L.I.1    Laycock, K.A.2    Jun, P.Y.3    Rader, K.A.4    Brady, R.H.5    Miller, J.K.6    Pepose, J.S.7    Leib, D.A.8
  • 35
    • 0027954256 scopus 로고
    • Herpes simplex virus type 1 strain KOS-63 does not cause acute or recurrent ocular disease and does not reactivate ganglionic latency in vivo
    • Berlin
    • Stroop, W. G., and M. C. Banks. 1994. Herpes simplex virus type 1 strain KOS-63 does not cause acute or recurrent ocular disease and does not reactivate ganglionic latency in vivo. Acta Neuropathol. (Berlin) 87:14-22.
    • (1994) Acta Neuropathol. , vol.87 , pp. 14-22
    • Stroop, W.G.1    Banks, M.C.2
  • 36
    • 0026030710 scopus 로고
    • Role of herpes simplex virus thymidine kinase expression in viral pathogenesis and latency
    • Tenser, R. B. 1991. Role of herpes simplex virus thymidine kinase expression in viral pathogenesis and latency. Intervirology 32:76-92.
    • (1991) Intervirology , vol.32 , pp. 76-92
    • Tenser, R.B.1
  • 37
    • 0022538538 scopus 로고
    • Functional and molecular analysis of the avirulent wild-type herpes simplex virus type 1 strain KOS
    • Thompson, R. L., M. L. Cook, G. Devi-Rao, E. K. Wagner, and J. G. Stevens. 1986. Functional and molecular analysis of the avirulent wild-type herpes simplex virus type 1 strain KOS. J. Virol. 58:203-211.
    • (1986) J. Virol. , vol.58 , pp. 203-211
    • Thompson, R.L.1    Cook, M.L.2    Devi-Rao, G.3    Wagner, E.K.4    Stevens, J.G.5
  • 38
    • 0030920240 scopus 로고    scopus 로고
    • The herpes simplex virus type 1 latency-associated transcript gene regulates the establishment of latency
    • Thompson, R. L., and N. M. Sawtell. 1997. The herpes simplex virus type 1 latency-associated transcript gene regulates the establishment of latency. J. Virol. 71:5432-5440.
    • (1997) J. Virol. , vol.71 , pp. 5432-5440
    • Thompson, R.L.1    Sawtell, N.M.2
  • 39
    • 0021031140 scopus 로고
    • Biological characterization of a herpes simplex virus intertypic recombinant which is completely and specifically non-neurovirulent
    • Thompson, R. L., and J. G. Stevens. 1983. Biological characterization of a herpes simplex virus intertypic recombinant which is completely and specifically non-neurovirulent. Virology 131:171-179.
    • (1983) Virology , vol.131 , pp. 171-179
    • Thompson, R.L.1    Stevens, J.G.2
  • 40
    • 0021041568 scopus 로고
    • Physical location of a herpes simplex virus type 1 gene function(s) specifically associated with a 10 million-fold increase in HSV neurovirulence
    • Thompson, R. L., E. K. Wagner, and J. G. Stevens. 1983. Physical location of a herpes simplex virus type 1 gene function(s) specifically associated with a 10 million-fold increase in HSV neurovirulence. Virology 131:180-192.
    • (1983) Virology , vol.131 , pp. 180-192
    • Thompson, R.L.1    Wagner, E.K.2    Stevens, J.G.3


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