Normalizing glycosphingolipids restores function in CD4+ T cells from lupus patients

Journal of Clinical Investigation

Volumn 124, Issue 2, 2014, Pages 712-724

  McDonald, Georgia ^a   Deepak, Shantal ^a   Miguel, Laura ^a   Hall, Cleo J ^a   Isenberg, David A ^a   Magee, Anthony I ^b   Butters, Terry ^c   Jury, Elizabeth C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1-DEOXYNOJIRIMYCIN; ADULT; AGED; ANTIGENS, CD; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; FEMALE; FLOW CYTOMETRY; G(M1) GANGLIOSIDE; GENE EXPRESSION REGULATION; GLYCOSPHINGOLIPIDS; HOMEOSTASIS; HUMANS; LACTOSYLCERAMIDES; LEUKOCYTES, MONONUCLEAR; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE ACTIVATION; MALE; MEMBRANE MICRODOMAINS; MIDDLE AGED; ORPHAN NUCLEAR RECEPTORS; SIGNAL TRANSDUCTION; TIME FACTORS; TRIHEXOSYLCERAMIDES;

EID: 84893835144     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI69571     Document Type: Article

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