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Volumn 49, Issue 5, 2008, Pages 1024-1033

Cholesterol supply and SREBPs modulate transcription of the niemann-pick C-1 gene in steroidogenic tissues

Author keywords

Cholesterol trafficking; Granulosa cells; Sterol regulatory element binding protein gene transcription

Indexed keywords

22 HYDROXYCHOLESTEROL; 25 HYDROXYCHOLESTEROL; CHOLESTEROL; HISTONE H3; LUCIFERASE; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1A; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; CARRIER PROTEIN; ISOPROTEIN; MEMBRANE PROTEIN; NPC1 PROTEIN, HUMAN; PRIMER DNA; RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN;

EID: 50049083375     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M700554-JLR200     Document Type: Conference Paper
Times cited : (29)

References (36)
  • 1
    • 30344473341 scopus 로고    scopus 로고
    • Protein sensors for membrane sterols
    • Goldstein, J. L., R. A. DeBose-Boyd, and M. S. Brown. 2006. Protein sensors for membrane sterols. Cell. 124: 35-46.
    • (2006) Cell , vol.124 , pp. 35-46
    • Goldstein, J.L.1    DeBose-Boyd, R.A.2    Brown, M.S.3
  • 2
    • 0031965513 scopus 로고    scopus 로고
    • Sterol regulatory element binding proteins (SREBPs): Controllers of lipid synthesis and cellular uptake
    • discussion 54-75
    • Brown, M. S., and J. L. Goldstein. 1998. Sterol regulatory element binding proteins (SREBPs): controllers of lipid synthesis and cellular uptake. Nutr. Rev. 56 (Suppl.): 1-3 (discussion 54-75).
    • (1998) Nutr. Rev , vol.56 , Issue.SUPPL. , pp. 1-3
    • Brown, M.S.1    Goldstein, J.L.2
  • 3
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton, J. D., J. L. Goldstein, and M. S. Brown. 2002. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 109: 1125-1131.
    • (2002) J. Clin. Invest , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 4
    • 0043172415 scopus 로고    scopus 로고
    • The SREBP pathway-insights from Insigs and insects
    • Rawson, R. B. 2003. The SREBP pathway-insights from Insigs and insects. Nat. Rev. Mol. Cell Biol. 4: 631-640.
    • (2003) Nat. Rev. Mol. Cell Biol , vol.4 , pp. 631-640
    • Rawson, R.B.1
  • 5
    • 10644239801 scopus 로고    scopus 로고
    • Cholesterol and 25- hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs
    • Adams, C. M.,J. Reitz, J. K De Brabander, J. D. Feramisco, L. Li, M. S. Brown, and J. L. Goldstein. 2004. Cholesterol and 25- hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs. J. Biol. Chem. 279: 52772-52780.
    • (2004) J. Biol. Chem , vol.279 , pp. 52772-52780
    • Adams, C.M.1    Reitz, J.2    De Brabander, J.K.3    Feramisco, J.D.4    Li, L.5    Brown, M.S.6    Goldstein, J.L.7
  • 6
    • 4444349833 scopus 로고    scopus 로고
    • Selective coactivator interactions in gene activation by SREBP-1a and -1c
    • Toth, J. I., S. Datta, J. N. Athanikar, L. P. Freedman, and T. F. Osborne. 2004. Selective coactivator interactions in gene activation by SREBP-1a and -1c. Mol. Cell. Biol. 24: 8288-8300.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 8288-8300
    • Toth, J.I.1    Datta, S.2    Athanikar, J.N.3    Freedman, L.P.4    Osborne, T.F.5
  • 7
    • 4944263713 scopus 로고    scopus 로고
    • Niemann-Pick C research from mouse to gene
    • Pentchev, P. G. 2004. Niemann-Pick C research from mouse to gene. Biochim. Biophys. Acta. 1685: 3-7.
    • (2004) Biochim. Biophys. Acta , vol.1685 , pp. 3-7
    • Pentchev, P.G.1
  • 8
    • 1542719049 scopus 로고    scopus 로고
    • The Niemann-Pick disease genes: Regulators of cellular cholesterol homeostasis
    • Ory, D. S. 2004. The Niemann-Pick disease genes: regulators of cellular cholesterol homeostasis. Trends Cardiovasc. Med. 14: 66-72.
    • (2004) Trends Cardiovasc. Med , vol.14 , pp. 66-72
    • Ory, D.S.1
  • 9
    • 20444396178 scopus 로고    scopus 로고
    • Niemann-Pick type C disease and intracellular cholesterol trafficking
    • Chang, T. Y., P. C. Reid, S. Sugii, N. Ohgami, J. C. Cruz, and C. C. Chang. 2005. Niemann-Pick type C disease and intracellular cholesterol trafficking. J. Biol. Chem. 280: 20917-20920.
    • (2005) J. Biol. Chem , vol.280 , pp. 20917-20920
    • Chang, T.Y.1    Reid, P.C.2    Sugii, S.3    Ohgami, N.4    Cruz, J.C.5    Chang, C.C.6
  • 10
    • 23344445128 scopus 로고    scopus 로고
    • The sterol-sensing domain of the Niemann-Pick C1 (NPC1) protein regulates trafficking of low-density lipoprotein cholesterol
    • Millard, E. E., S. E. Gale, N. Dudley, J. Zhang, J. E. Schaffer, and D. S. Ory. 2005. The sterol-sensing domain of the Niemann-Pick C1 (NPC1) protein regulates trafficking of low-density lipoprotein cholesterol. J. Biol. Chem. 280: 28581-28590.
    • (2005) J. Biol. Chem , vol.280 , pp. 28581-28590
    • Millard, E.E.1    Gale, S.E.2    Dudley, N.3    Zhang, J.4    Schaffer, J.E.5    Ory, D.S.6
  • 12
    • 12444315104 scopus 로고    scopus 로고
    • Regulation of Niemann-Pick C1 gene expression by the 3′5′ cyclic adenosine monophosphate pathway in steroidogenic cells
    • Gevry, N. Y., E. Lalli, P. Sassone-Corsi, and B. D. Murphy. 2003. Regulation of Niemann-Pick C1 gene expression by the 3′5′ cyclic adenosine monophosphate pathway in steroidogenic cells. Mol. Endocrinol. 17: 704-715.
    • (2003) Mol. Endocrinol , vol.17 , pp. 704-715
    • Gevry, N.Y.1    Lalli, E.2    Sassone-Corsi, P.3    Murphy, B.D.4
  • 13
    • 0036153672 scopus 로고    scopus 로고
    • Porcine Niemann-Pick C1 protein is expressed in steroidogenic tissues and modulated by cAMP
    • Gevry, N., D. Lacroix, J. H. Song, N. Pescador, M. Dobias, and B. D. Murphy. 2002. Porcine Niemann-Pick C1 protein is expressed in steroidogenic tissues and modulated by cAMP. Endocrinology. 143: 708-716.
    • (2002) Endocrinology , vol.143 , pp. 708-716
    • Gevry, N.1    Lacroix, D.2    Song, J.H.3    Pescador, N.4    Dobias, M.5    Murphy, B.D.6
  • 15
    • 23244444808 scopus 로고    scopus 로고
    • Niemann-Pick C1 (NPC1) expression is not regulated by the amount of cholesterol flowing through cells in the mouse
    • Garver, W. S., C. Xie, J. J. Repa, S. D. Turley, and J. M. Dietschy. 2005. Niemann-Pick C1 (NPC1) expression is not regulated by the amount of cholesterol flowing through cells in the mouse. J. Lipid Res. 46: 1745-1754.
    • (2005) J. Lipid Res , vol.46 , pp. 1745-1754
    • Garver, W.S.1    Xie, C.2    Repa, J.J.3    Turley, S.D.4    Dietschy, J.M.5
  • 16
    • 43249098329 scopus 로고    scopus 로고
    • The Niemann-Pick C1 gene is downregulated by feedback inhibition of the SREBP pathway in human fibroblasts
    • In press
    • Garver, W. S., D. Jelinek, G. A. Francis, and B. D. Murphy. 2008. The Niemann-Pick C1 gene is downregulated by feedback inhibition of the SREBP pathway in human fibroblasts. J. Lipid. Res. In press.
    • (2008) J. Lipid. Res
    • Garver, W.S.1    Jelinek, D.2    Francis, G.A.3    Murphy, B.D.4
  • 17
    • 0036933005 scopus 로고    scopus 로고
    • The role and regulation of the Niemann-Pick C1 gene in adrenal steroidogenesis
    • Gevry, N. Y., and B. D. Murphy. 2002. The role and regulation of the Niemann-Pick C1 gene in adrenal steroidogenesis. Endocr. Res. 28: 403-412.
    • (2002) Endocr. Res , vol.28 , pp. 403-412
    • Gevry, N.Y.1    Murphy, B.D.2
  • 18
    • 0034406804 scopus 로고    scopus 로고
    • Induction of LPL gene expression by sterols is mediated by a sterol regulatory element and is independent of the presence of multiple E boxes
    • Schoonjans, K., L. Gelman, C. Haby, M. Briggs, and J. Auwerx. 2000. Induction of LPL gene expression by sterols is mediated by a sterol regulatory element and is independent of the presence of multiple E boxes. J. Mol. Biol. 304: 323-334.
    • (2000) J. Mol. Biol , vol.304 , pp. 323-334
    • Schoonjans, K.1    Gelman, L.2    Haby, C.3    Briggs, M.4    Auwerx, J.5
  • 19
    • 0033041661 scopus 로고    scopus 로고
    • Growth factor modulation of steroidogenic acute regulatory protein and lutein- ization in the pig ovary
    • Pescador, N., D. M. Stocco, and B. D. Murphy. 1999. Growth factor modulation of steroidogenic acute regulatory protein and lutein- ization in the pig ovary. Biol. Reprod. 60: 1453-1461.
    • (1999) Biol. Reprod , vol.60 , pp. 1453-1461
    • Pescador, N.1    Stocco, D.M.2    Murphy, B.D.3
  • 20
    • 0029957280 scopus 로고    scopus 로고
    • Steroidogenic properties of a spontaneously established porcine granulosa cell line (PGC-2)
    • Kwan, I., R. Farookhi, H. T. Huynh, B. D. Murphy, J. D. Turner, and B. R. Downey. 1996. Steroidogenic properties of a spontaneously established porcine granulosa cell line (PGC-2). Mol. Reprod. Dev. 45: 299-307.
    • (1996) Mol. Reprod. Dev , vol.45 , pp. 299-307
    • Kwan, I.1    Farookhi, R.2    Huynh, H.T.3    Murphy, B.D.4    Turner, J.D.5    Downey, B.R.6
  • 21
    • 0033388858 scopus 로고    scopus 로고
    • In vivo cross-linking and immunoprecipitation for studying dynamic protein:DNA associations in a chromatin environment
    • Kuo, M. H., and C. D. Allis. 1999. In vivo cross-linking and immunoprecipitation for studying dynamic protein:DNA associations in a chromatin environment. Methods. 19: 425-433.
    • (1999) Methods , vol.19 , pp. 425-433
    • Kuo, M.H.1    Allis, C.D.2
  • 22
    • 0037088683 scopus 로고    scopus 로고
    • Diminished hepatic response to fasting/ refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c
    • Liang, G., J. Yang, J. D. Horton, R. E. Hammer, J. L. Goldstein, and M. S. Brown. 2002. Diminished hepatic response to fasting/ refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c. J. Biol. Chem. 277: 9520-9528.
    • (2002) J. Biol. Chem , vol.277 , pp. 9520-9528
    • Liang, G.1    Yang, J.2    Horton, J.D.3    Hammer, R.E.4    Goldstein, J.L.5    Brown, M.S.6
  • 23
    • 0034612227 scopus 로고    scopus 로고
    • Nutrient regulation of gene expression by the sterol regulatory element binding proteins: Increased recruitment of gene-specific coregulatory factors and selective hyperacetylation of histone H3 in vivo
    • Bennett, M. K., and T. F. Osborne. 2000. Nutrient regulation of gene expression by the sterol regulatory element binding proteins: increased recruitment of gene-specific coregulatory factors and selective hyperacetylation of histone H3 in vivo. Proc. Natl. Acad. Sci. USA. 97: 6340-6344.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6340-6344
    • Bennett, M.K.1    Osborne, T.F.2
  • 24
    • 3042711799 scopus 로고    scopus 로고
    • Aberrant intracellular cholesterol transport gene disrupts pituitary and ovarian function
    • Gévry, N. Y., F. Lopes, S. Ledoux, and B. D. Murphy. 2004. Aberrant intracellular cholesterol transport gene disrupts pituitary and ovarian function. Mol. Endocrinol. 18: 1778-1786.
    • (2004) Mol. Endocrinol , vol.18 , pp. 1778-1786
    • Gévry, N.Y.1    Lopes, F.2    Ledoux, S.3    Murphy, B.D.4
  • 25
    • 10344228820 scopus 로고    scopus 로고
    • Sterol-responsive element- binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: A novel role of SREBP in regulating cholesterol metabolism
    • Zeng, L., H. Liao, Y. Liu, T. S. Lee, M. Zhu, X. Wang, M. B. Stemerman, Y. Zhu, and J. Y. Shyy. 2004. Sterol-responsive element- binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism. J. Biol. Chem. 279: 48801-48807.
    • (2004) J. Biol. Chem , vol.279 , pp. 48801-48807
    • Zeng, L.1    Liao, H.2    Liu, Y.3    Lee, T.S.4    Zhu, M.5    Wang, X.6    Stemerman, M.B.7    Zhu, Y.8    Shyy, J.Y.9
  • 27
    • 0034714439 scopus 로고    scopus 로고
    • Determinants of NPC1 expression and action: Key promoter regions, posttranscriptional control, and the importance of a "cysteine-rich" loop
    • Watari, H., E.J. Blanchette-Mackie, N. K Dwyer, M. Watari, C. G. Burd, S. Patel, P. G. Pentchev, and J. F. Strauss, 3rd. 2000. Determinants of NPC1 expression and action: key promoter regions, posttranscriptional control, and the importance of a "cysteine-rich" loop. Exp. Cell Res. 259: 247-256.
    • (2000) Exp. Cell Res , vol.259 , pp. 247-256
    • Watari, H.1    Blanchette-Mackie, E.J.2    Dwyer, N.K.3    Watari, M.4    Burd, C.G.5    Patel, S.6    Pentchev, P.G.7    Strauss 3rd, J.F.8
  • 28
    • 0037271322 scopus 로고    scopus 로고
    • Cross-species sequence comparisons: A review of methods and available resources
    • Frazer, K. A., L. Elnitski, D. M. Church, I. Dubchak, and R. C. Hardison. 2003. Cross-species sequence comparisons: a review of methods and available resources. Genome Res. 13: 1-12.
    • (2003) Genome Res , vol.13 , pp. 1-12
    • Frazer, K.A.1    Elnitski, L.2    Church, D.M.3    Dubchak, I.4    Hardison, R.C.5
  • 29
    • 3042741134 scopus 로고    scopus 로고
    • Involvement of Sp1 and SREBP- 1a in transcriptional activation of the LDL receptor gene by insulin and LH in cultured porcine granulosa-luteal cells
    • Sekar, N., and J. D. Veldhuis. 2004. Involvement of Sp1 and SREBP- 1a in transcriptional activation of the LDL receptor gene by insulin and LH in cultured porcine granulosa-luteal cells. Am. J. Physiol. Endocrinol. Metab. 287: E128-E135.
    • (2004) Am. J. Physiol. Endocrinol. Metab , vol.287
    • Sekar, N.1    Veldhuis, J.D.2
  • 30
    • 0028225462 scopus 로고
    • SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
    • Wang, X., R. Sato, M. S. Brown, X. Hua, and J. L. Goldstein. 1994. SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis. Cell. 77: 53-62.
    • (1994) Cell , vol.77 , pp. 53-62
    • Wang, X.1    Sato, R.2    Brown, M.S.3    Hua, X.4    Goldstein, J.L.5
  • 32
    • 0027190308 scopus 로고
    • Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. I. Identification of the protein and delineation of its target nucleotide sequence
    • Briggs, M. R., C. Yokoyama, X. Wang, M. S. Brown, and J. L. Goldstein. 1993. Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. I. Identification of the protein and delineation of its target nucleotide sequence. J. Biol. Chem. 268: 14490-14496.
    • (1993) J. Biol. Chem , vol.268 , pp. 14490-14496
    • Briggs, M.R.1    Yokoyama, C.2    Wang, X.3    Brown, M.S.4    Goldstein, J.L.5
  • 33
  • 34
    • 0032568557 scopus 로고    scopus 로고
    • Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice
    • Horton, J. D., Y. Bashmakov, I. Shimomura, and H. Shimano. 1998. Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice. Proc. Natl. Acad. Sci. USA. 95: 5987-5992.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5987-5992
    • Horton, J.D.1    Bashmakov, Y.2    Shimomura, I.3    Shimano, H.4
  • 35
    • 66249102006 scopus 로고    scopus 로고
    • Gévry, N. Y., and B. D. Murphy. 2002. The role of sterol regulatory element-binding proteins in the transactivation of Niemann-C1 promoter (Presented at the Annual Meeting, Endocrine Society, San Francisco, CA. June 19-22).
    • Gévry, N. Y., and B. D. Murphy. 2002. The role of sterol regulatory element-binding proteins in the transactivation of Niemann-C1 promoter (Presented at the Annual Meeting, Endocrine Society, San Francisco, CA. June 19-22).
  • 36
    • 0034110003 scopus 로고    scopus 로고
    • Multiple mechanisms, independent of sterol regulatory element binding proteins, regulate low density lipoprotein gene transcription
    • Makar, R. S., P. E. Lipsky, and J. A. Cuthbert. 2000. Multiple mechanisms, independent of sterol regulatory element binding proteins, regulate low density lipoprotein gene transcription. J. Lipid Res. 41: 762-774.
    • (2000) J. Lipid Res , vol.41 , pp. 762-774
    • Makar, R.S.1    Lipsky, P.E.2    Cuthbert, J.A.3


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