Synthesis of triazole-functionalized 2-DOS analogues and their evaluation as A-site binders

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 4, 2014, Pages 1122-1126

  Anastasopoulou, Panoula ^a   Kythreoti, Georgia ^a   Cosmidis, Tilemachos ^a   Pyrkotis, Constantina ^a   Nahmias, Victoria R ^a   Vourloumis, Dionisios ^a  

^a INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

Author keywords

2 Deoxystreptamine; Aminoglycosides; Orthogonal protection strategy; Ribosomal A site; RNA recognition

Indexed keywords

2-DEOXYSTREPTAMINE; AMINOGLYCOSIDES; ORTHOGONAL PROTECTION STRATEGY; RIBOSOMAL A-SITE; RNA RECOGNITION;

ANTI-BACTERIAL AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; HEXOSAMINES; MICROBIAL SENSITIVITY TESTS; MOLECULAR CONFORMATION; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 84893790198     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.12.125     Document Type: Article

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