-
1
-
-
78649705269
-
Systematic review of pharmacoeconomic studies of pharmacogenomic tests
-
Beaulieu M, de Denus S and Lachaine J. Systematic review of pharmacoeconomic studies of pharmacogenomic tests. Pharmacogenomics 2010; 11: 1573-1590.
-
(2010)
Pharmacogenomics
, vol.11
, pp. 1573-1590
-
-
Beaulieu, M.1
de Denus, S.2
Lachaine, J.3
-
2
-
-
0035775486
-
Pharmacogenomics: The inherited basis for interindividual differences in drug response
-
Lander E, Page D and Lifton R (eds)
-
Evans WE and Johnson JA. Pharmacogenomics: the inherited basis for interindividual differences in drug response. In: Lander E, Page D and Lifton R (eds) Annual review of genomics and human genetics, 2001.
-
(2001)
Annual Review of Genomics and Human Genetics
-
-
Evans, W.E.1
Johnson, J.A.2
-
3
-
-
0035033019
-
Pharmacogenomics: Unlocking the human genome for better drug therapy
-
McLeod HL and Evans WE. Pharmacogenomics: unlocking the human genome for better drug therapy. Annu Rev Pharmacol Toxicol 2001; 41: 101-121.
-
(2001)
Annu Rev Pharmacol Toxicol
, vol.41
, pp. 101-121
-
-
McLeod, H.L.1
Evans, W.E.2
-
4
-
-
44649187964
-
A review of public policy issues in promoting the development and commercialization of pharmacogenomic applications: Challenges and implications
-
Garrison LP, Carlson RJ, Carlson JJ, et al. A review of public policy issues in promoting the development and commercialization of pharmacogenomic applications: challenges and implications. Drug Metab Rev 2008; 40: 377-401.
-
(2008)
Drug Metab Rev
, vol.40
, pp. 377-401
-
-
Garrison, L.P.1
Carlson, R.J.2
Carlson, J.J.3
-
5
-
-
0035861049
-
Potential role of pharmacogenomics in reducing adverse drug reactions - a systematic review
-
Phillips KA, Veenstra DL, Oren E, et al. Potential role of pharmacogenomics in reducing adverse drug reactions - a systematic review. Jama-J Am Med Assoc 2001; 286: 2270-2279.
-
(2001)
Jama-J Am Med Assoc
, vol.286
, pp. 2270-2279
-
-
Phillips, K.A.1
Veenstra, D.L.2
Oren, E.3
-
7
-
-
77957995461
-
Cost effectiveness of pharmacogenomics: A critical and systematic review
-
Wong WB, Carlson JJ, Thariani R, et al. Cost effectiveness of pharmacogenomics: a critical and systematic review. Pharmacoeconomics 2010; 28: 1001-1013.
-
(2010)
Pharmacoeconomics
, vol.28
, pp. 1001-1013
-
-
Wong, W.B.1
Carlson, J.J.2
Thariani, R.3
-
8
-
-
34548385836
-
Translating pharmacogenomics: Challenges on the road to the clinic
-
Swen JJ, Huizinga TW, Gelderblom H, et al. Translating pharmacogenomics: challenges on the road to the clinic. Plos Med 2007; 4: 1317-1324.
-
(2007)
Plos Med
, vol.4
, pp. 1317-1324
-
-
Swen, J.J.1
Huizinga, T.W.2
Gelderblom, H.3
-
9
-
-
80054880042
-
Pharmacoproteomics of obesity: Definitions, role and a case study of dynamics of human plasma proteome
-
Andreev VP. Pharmacoproteomics of obesity: definitions, role and a case study of dynamics of human plasma proteome. Pharmacogenomics 2011; 12: 1363-1365.
-
(2011)
Pharmacogenomics
, vol.12
, pp. 1363-1365
-
-
Andreev, V.P.1
-
10
-
-
78649629973
-
Pharmacoproteomics: A chess game on a protein field
-
D'Alessandro A and Zolla L. Pharmacoproteomics: a chess game on a protein field. Drug Discovery Today 2010; 15: 1015-1023.
-
(2010)
Drug Discovery Today
, vol.15
, pp. 1015-1023
-
-
D'Alessandro, A.1
Zolla, L.2
-
11
-
-
33646198860
-
Pharmaco-metabonomic phenotyping and personalized drug treatment
-
Clayton T, Lindon J, Cloarec O, et al. Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature 2006; 440: 1073-1077.
-
(2006)
Nature
, vol.440
, pp. 1073-1077
-
-
Clayton, T.1
Lindon, J.2
Cloarec, O.3
-
12
-
-
0034368580
-
Metabonomics: Metabolic processes studied by NMR spectroscopy of biofluids
-
Lindon J, Nicholson J, Holmes E, et al. Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts Magn Reson 2000; 12: 289-320.
-
(2000)
Concepts Magn Reson
, vol.12
, pp. 289-320
-
-
Lindon, J.1
Nicholson, J.2
Holmes, E.3
-
13
-
-
0032694577
-
'Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
-
Nicholson JK, Lindon JC and Holmes E. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 1999; 29: 1181-1189.
-
(1999)
Xenobiotica
, vol.29
, pp. 1181-1189
-
-
Nicholson, J.K.1
Lindon, J.C.2
Holmes, E.3
-
14
-
-
0345470490
-
Human metabolic profiles obtained by GC and GC/MS
-
Horning EC and Horning MG. Human metabolic profiles obtained by GC and GC/MS. J Chromatogr Sci 1971; 9: 129.
-
(1971)
J Chromatogr Sci
, vol.9
, pp. 129
-
-
Horning, E.C.1
Horning, M.G.2
-
15
-
-
0017528546
-
Profiling of human-body fluids in healthy and diseased states using gas-chromatography and mass-spectrometry, with special reference to organic-acids
-
Jellum E. Profiling of human-body fluids in healthy and diseased states using gas-chromatography and mass-spectrometry, with special reference to organic-acids. J Chromatogr 1977; 143: 427-462.
-
(1977)
J Chromatogr
, vol.143
, pp. 427-462
-
-
Jellum, E.1
-
16
-
-
0018137689
-
Quantitative metabolic profiling based on gas-chromatography
-
Gates SC and Sweeley CC. Quantitative metabolic profiling based on gas-chromatography. Clin Chem 1978; 24: 1663-1673.
-
(1978)
Clin Chem
, vol.24
, pp. 1663-1673
-
-
Gates, S.C.1
Sweeley, C.C.2
-
17
-
-
0021265851
-
Spin-echo H-1NMR spectroscopy-a new method for studying penicillin metabolism
-
Everett J, Jennings K, Woodnutt G, et al. Spin-echo H-1NMR spectroscopy-a new method for studying penicillin metabolism. J Chem Soc Chem Commun 1984; 894-895.
-
(1984)
J Chem Soc Chem Commun
, pp. 894-895
-
-
Everett, J.1
Jennings, K.2
Woodnutt, G.3
-
19
-
-
84882811844
-
High-resolution NMR spectroscopy of biofluids and applications in drug metabolism
-
Everett JR. High-resolution NMR spectroscopy of biofluids and applications in drug metabolism. Anal Proc 1991; 28: 181-183.
-
(1991)
Anal Proc
, vol.28
, pp. 181-183
-
-
Everett, J.R.1
-
20
-
-
18144391608
-
Biofluid NMR spectroscopy in the study of the metabolism of-Lactam antibiotics
-
In: Reid E and Wilson I, Cambridge: Royal Society of Chemistry
-
Everett JR. Biofluid NMR spectroscopy in the study of the metabolism of-Lactam antibiotics. In: Reid E and Wilson I (eds) Bioanalytical approaches for drugs, including anti-asthmatics and metabolities. Cambridge: Royal Society of Chemistry, 1992, pp.3-10.
-
(1992)
Bioanalytical Approaches For Drugs, Including Anti-asthmatics and Metabolities
, pp. 3-10
-
-
Everett, J.R.1
-
25
-
-
77952205557
-
Global metabolic profiling procedures for urine using UPLC-MS
-
Want EJ, Wilson ID, Gika H, et al. Global metabolic profiling procedures for urine using UPLC-MS. Nat Protoc 2010; 5: 1005-1018.
-
(2010)
Nat Protoc
, vol.5
, pp. 1005-1018
-
-
Want, E.J.1
Wilson, I.D.2
Gika, H.3
-
26
-
-
66349087823
-
Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics
-
Lindon JC and Nicholson JK. Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics. Annu Rev Anal Chem 2008; 1: 45-69.
-
(2008)
Annu Rev Anal Chem
, vol.1
, pp. 45-69
-
-
Lindon, J.C.1
Nicholson, J.K.2
-
27
-
-
0036007687
-
Metabolomics-the link between genotypes and phenotypes
-
Fiehn O. Metabolomics-the link between genotypes and phenotypes. Plant Mol Biol 2002; 48: 155-171.
-
(2002)
Plant Mol Biol
, vol.48
, pp. 155-171
-
-
Fiehn, O.1
-
28
-
-
0033757963
-
Metabolite profiling for plant functional genomics
-
Fiehn O, Kopka J, Dormann P, et al. Metabolite profiling for plant functional genomics. Nat Biotechnol 2000; 18: 1157-1161.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 1157-1161
-
-
Fiehn, O.1
Kopka, J.2
Dormann, P.3
-
29
-
-
33750719994
-
Global systems biology, personalized medicine and molecular epidemiology
-
Nicholson JK. Global systems biology, personalized medicine and molecular epidemiology. Mol Syst Biol 2006; 2: 52.
-
(2006)
Mol Syst Biol
, vol.2
, pp. 52
-
-
Nicholson, J.K.1
-
32
-
-
84866087835
-
Pharmacometabonomic characterization of xenobiotic and endogenous metabolic phenotypes that account for inter-individual variation in isoniazid-induced toxicological response
-
Cunningham K, Claus SP, Lindon JC, et al. Pharmacometabonomic characterization of xenobiotic and endogenous metabolic phenotypes that account for inter-individual variation in isoniazid-induced toxicological response. J Proteome Res 2012; 11: 4630-4642.
-
(2012)
J Proteome Res
, vol.11
, pp. 4630-4642
-
-
Cunningham, K.1
Claus, S.P.2
Lindon, J.C.3
-
34
-
-
78650737804
-
Advances in structure elucidation of small molecules using mass spectrometry
-
Kind T and Fiehn O. Advances in structure elucidation of small molecules using mass spectrometry. Bioanal Rev 2010; 2: 23-60.
-
(2010)
Bioanal Rev
, vol.2
, pp. 23-60
-
-
Kind, T.1
Fiehn, O.2
-
35
-
-
78649317973
-
LC-MS metabonomics methodology in biomarker discovery
-
In: Wang F (ed.), Totowa: Humana Press
-
Lu X and Xu G. LC-MS metabonomics methodology in biomarker discovery. In: Wang F (ed.) Biomarker methods in drug discovery and development. Totowa: Humana Press, 2008, pp.291-315.
-
(2008)
Biomarker Methods In Drug Discovery and Development
, pp. 291-315
-
-
Lu, X.1
Xu, G.2
-
36
-
-
78650907092
-
Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: A review
-
Roux A, Lison D, Junot C, et al. Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: A review. Clin Biochem 2011; 44: 119-135.
-
(2011)
Clin Biochem
, vol.44
, pp. 119-135
-
-
Roux, A.1
Lison, D.2
Junot, C.3
-
37
-
-
79960495785
-
Mass spectrometry-based holistic analytical approaches for metabolite profiling in systems biology studies
-
Theodoridis G, Gika HG and Wilson ID. Mass spectrometry-based holistic analytical approaches for metabolite profiling in systems biology studies. Mass Spectrom Rev 2011; 30: 884-906.
-
(2011)
Mass Spectrom Rev
, vol.30
, pp. 884-906
-
-
Theodoridis, G.1
Gika, H.G.2
Wilson, I.D.3
-
38
-
-
83055186403
-
Liquid chromatography-mass spectrometry based global metabolite profiling: A review
-
Theodoridis GA, Gika HG, Want EJ, et al. Liquid chromatography-mass spectrometry based global metabolite profiling: a review. Anal Chim Acta 2012; 711: 7-16.
-
(2012)
Anal Chim Acta
, vol.711
, pp. 7-16
-
-
Theodoridis, G.A.1
Gika, H.G.2
Want, E.J.3
-
40
-
-
13244249953
-
Chemical derivatization and mass spectral libraries in metabolic profiling by GC/MS and LC/MS/MS
-
Halket JM, Waterman D, Przyborowska AM, et al. Chemical derivatization and mass spectral libraries in metabolic profiling by GC/MS and LC/MS/MS. J Exp Bot 2005; 56: 219-243.
-
(2005)
J Exp Bot
, vol.56
, pp. 219-243
-
-
Halket, J.M.1
Waterman, D.2
Przyborowska, A.M.3
-
42
-
-
66349087823
-
Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics
-
Lindon JC and Nicholson JK. Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics. Annu Rev Anal Chem (Palo Alto Calif) 2008; 1: 45-69.
-
(2008)
Annu Rev Anal Chem (Palo Alto Calif)
, vol.1
, pp. 45-69
-
-
Lindon, J.C.1
Nicholson, J.K.2
-
43
-
-
0036083139
-
Orthogonal projections to latent structures (O-PLS)
-
Trygg J and Wold S. Orthogonal projections to latent structures (O-PLS). J Chemom 2002; 16: 119-128.
-
(2002)
J Chemom
, vol.16
, pp. 119-128
-
-
Trygg, J.1
Wold, S.2
-
44
-
-
34247131764
-
Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy
-
Holmes E, Loo RL, Cloarec O, et al. Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy. Anal Chem 2007; 79: 2629-2640.
-
(2007)
Anal Chem
, vol.79
, pp. 2629-2640
-
-
Holmes, E.1
Loo, R.L.2
Cloarec, O.3
-
45
-
-
0027511147
-
The correlation between urinary and liver taurine levels and between pre-dose urinary taurine and liver damage
-
Waterfield CJ, Turton JA, Scales MD, et al. The correlation between urinary and liver taurine levels and between pre-dose urinary taurine and liver damage. Toxicology 1993; 77: 1-5.
-
(1993)
Toxicology
, vol.77
, pp. 1-5
-
-
Waterfield, C.J.1
Turton, J.A.2
Scales, M.D.3
-
48
-
-
0030200709
-
Different mechanism of saturation of acetaminophen sulfate conjugation in mice and rats
-
Liu L and Klaassen CD. Different mechanism of saturation of acetaminophen sulfate conjugation in mice and rats. Toxicol Appl Pharmacol 1996; 139: 128-134.
-
(1996)
Toxicol Appl Pharmacol
, vol.139
, pp. 128-134
-
-
Liu, L.1
Klaassen, C.D.2
-
49
-
-
33750202863
-
Can personalized drug therapy be achieved? A closer look at pharmaco-metabonomics
-
Nebert DW and Vesell ES. Can personalized drug therapy be achieved? A closer look at pharmaco-metabonomics. Trends Pharmacol Sci 2006; 27: 580-586.
-
(2006)
Trends Pharmacol Sci
, vol.27
, pp. 580-586
-
-
Nebert, D.W.1
Vesell, E.S.2
-
51
-
-
34248139693
-
Pharmacometabonomic phenotyping reveals different responses to xenobiotic intervention in rats
-
Li H, Ni Y, Su M, et al. Pharmacometabonomic phenotyping reveals different responses to xenobiotic intervention in rats. J Proteome Res 2007; 6: 1364-1370.
-
(2007)
J Proteome Res
, vol.6
, pp. 1364-1370
-
-
Li, H.1
Ni, Y.2
Su, M.3
-
52
-
-
79953663708
-
Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells
-
Cavill R, Kamburov A, Ellis JK, et al. Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells. PLoS Comput Biol 2011; 7: e1001113.
-
(2011)
PLoS Comput Biol
, vol.7
-
-
Cavill, R.1
Kamburov, A.2
Ellis, J.K.3
-
53
-
-
79951678399
-
Predicting idiopathic toxicity of cisplatin by a pharmacometabonomic approach
-
Kwon HN, Kim M, Wen H, et al. Predicting idiopathic toxicity of cisplatin by a pharmacometabonomic approach. Kidney Int 2011; 79: 529-537.
-
(2011)
Kidney Int
, vol.79
, pp. 529-537
-
-
Kwon, H.N.1
Kim, M.2
Wen, H.3
-
54
-
-
84859594012
-
Pharmacometabonomic investigation of dynamic metabolic phenotypes associated with variability in response to galactosamine hepatotoxicity
-
Coen M, Goldfain-Blanc F, Rolland-Valognes G, et al. Pharmacometabonomic investigation of dynamic metabolic phenotypes associated with variability in response to galactosamine hepatotoxicity. J Proteome Res 2012; 11: 2427-2440.
-
(2012)
J Proteome Res
, vol.11
, pp. 2427-2440
-
-
Coen, M.1
Goldfain-Blanc, F.2
Rolland-Valognes, G.3
-
55
-
-
84859773739
-
Impact of intestinal microbiota on intestinal luminal metabolome
-
Matsumoto M, Kibe R, Ooga T, et al. Impact of intestinal microbiota on intestinal luminal metabolome. Sci Rep 2012; 2: 233.
-
(2012)
Sci Rep
, vol.2
, pp. 233
-
-
Matsumoto, M.1
Kibe, R.2
Ooga, T.3
-
56
-
-
84865089299
-
Prediction of the pharmacokinetic parameters of triptolide in rats based on endogenous molecules in pre-dose baseline serum
-
Liu L, Cao B, Aa J, et al. Prediction of the pharmacokinetic parameters of triptolide in rats based on endogenous molecules in pre-dose baseline serum. PLoS One 2012; 7: e43389.
-
(2012)
PLoS One
, vol.7
-
-
Liu, L.1
Cao, B.2
Aa, J.3
-
57
-
-
79951851704
-
XPB, a subunit of TFIIH, is a target of the natural product triptolide
-
Titov DV, Gilman B, He Q-L, et al. XPB, a subunit of TFIIH, is a target of the natural product triptolide. Nat Chem Biol 2011; 7: 182-188.
-
(2011)
Nat Chem Biol
, vol.7
, pp. 182-188
-
-
Titov, D.V.1
Gilman, B.2
He, Q.-L.3
-
58
-
-
70149096873
-
Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism
-
Clayton TA, Baker D, Lindon JC, et al. Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proc Natl Acad Sci USA 2009; 106: 14728-14733.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14728-14733
-
-
Clayton, T.A.1
Baker, D.2
Lindon, J.C.3
-
59
-
-
34748846290
-
Metabolomic mapping of atypical antipsychotic effects in schizophrenia
-
Kaddurah-Daouk R, McEvoy J, Baillie RA, et al. Metabolomic mapping of atypical antipsychotic effects in schizophrenia. Mol Psychiatry 2007; 12: 934-945.
-
(2007)
Mol Psychiatry
, vol.12
, pp. 934-945
-
-
Kaddurah-Daouk, R.1
McEvoy, J.2
Baillie, R.A.3
-
60
-
-
79955419677
-
Methodological quality in pharmacogenetic studies with binary assessment of treatment response: A review
-
Cobos A, Sanchez P, Aguado J, et al. Methodological quality in pharmacogenetic studies with binary assessment of treatment response: a review. Pharm Genomics 2011; 21: 243-250.
-
(2011)
Pharm Genomics
, vol.21
, pp. 243-250
-
-
Cobos, A.1
Sanchez, P.2
Aguado, J.3
-
61
-
-
0030888455
-
Formation of phenolic and indolic compounds by anaerobic bacteria in the human large intestine
-
Smith EA and Macfarlane GT. Formation of phenolic and indolic compounds by anaerobic bacteria in the human large intestine. Microb Ecol 1997; 33: 180-188.
-
(1997)
Microb Ecol
, vol.33
, pp. 180-188
-
-
Smith, E.A.1
Macfarlane, G.T.2
-
62
-
-
79955145983
-
The analysis of para-cresol production and tolerance in Clostridium difficile 027 and 012 strains
-
Dawson LF, Donahue EH, Cartman ST, et al. The analysis of para-cresol production and tolerance in Clostridium difficile 027 and 012 strains. BMC Microbiol 2011; 11: 86-95.
-
(2011)
BMC Microbiol
, vol.11
, pp. 86-95
-
-
Dawson, L.F.1
Donahue, E.H.2
Cartman, S.T.3
-
63
-
-
33846659447
-
P-cresylsulphate, the main in vivo metabolite of p-cresol, activates leucocyte free radical production
-
Schepers E, Meert N, Glorieux G, et al. P-cresylsulphate, the main in vivo metabolite of p-cresol, activates leucocyte free radical production. Nephrol Dial Transplant 2007; 22: 592-596.
-
(2007)
Nephrol Dial Transplant
, vol.22
, pp. 592-596
-
-
Schepers, E.1
Meert, N.2
Glorieux, G.3
-
64
-
-
33144464115
-
Human sulfotransferases and their role in chemical metabolism
-
Gamage N, Barnett A, Hempel N, et al. Human sulfotransferases and their role in chemical metabolism. Toxicol Sci 2006; 90: 5-22.
-
(2006)
Toxicol Sci
, vol.90
, pp. 5-22
-
-
Gamage, N.1
Barnett, A.2
Hempel, N.3
-
65
-
-
0031136606
-
0phosphosulfate (PAPS) in the regulation of sulfation
-
0phosphosulfate (PAPS) in the regulation of sulfation. FASEB J 1997; 11: 404-418.
-
(1997)
FASEB J
, vol.11
, pp. 404-418
-
-
Klaassen, C.D.1
Boles, J.W.2
-
66
-
-
70149092771
-
Drugs, bugs, and personalized medicine: Pharmacometabonomics enters the ring
-
Wilson ID. Drugs, bugs, and personalized medicine: pharmacometabonomics enters the ring. Proc Natl Acad Sci USA 2009; 106: 14187-14188.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14187-14188
-
-
Wilson, I.D.1
-
67
-
-
79955084411
-
Pharmacometabonomics, pharmacogenomics and personalized medicine
-
Gutiu IA, Andries A, Mircioiu C, et al. Pharmacometabonomics, pharmacogenomics and personalized medicine. Rom J Intern Med 2010; 48: 187-191.
-
(2010)
Rom J Intern Med
, vol.48
, pp. 187-191
-
-
Gutiu, I.A.1
Andries, A.2
Mircioiu, C.3
-
68
-
-
84859383638
-
Pharma-metabolomics in neonatology: Is it a dream or a fact?
-
Fanos V, Barberini L, Antonucci R, et al. Pharma-metabolomics in neonatology: is it a dream or a fact? Curr Pharm Des 2012; 18: 2996-3006.
-
(2012)
Curr Pharm Des
, vol.18
, pp. 2996-3006
-
-
Fanos, V.1
Barberini, L.2
Antonucci, R.3
-
69
-
-
70350716444
-
Serum molecular signatures of weight change during early breast cancer chemotherapy
-
Keun HC, Sidhu J, Pchejetski D, et al. Serum molecular signatures of weight change during early breast cancer chemotherapy. Clin Cancer Res 2009; 15: 6716-6723.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6716-6723
-
-
Keun, H.C.1
Sidhu, J.2
Pchejetski, D.3
-
70
-
-
77949875295
-
An integrative approach for identifying a metabolic phenotype predictive of individualized pharmacokinetics of tacrolimus
-
Phapale PB, Kim SD, Lee HW, et al. An integrative approach for identifying a metabolic phenotype predictive of individualized pharmacokinetics of tacrolimus. Clin Pharmacol Ther 2010; 87: 426-436.
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 426-436
-
-
Phapale, P.B.1
Kim, S.D.2
Lee, H.W.3
-
71
-
-
33745607004
-
Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily-A randomized controlled trial
-
Watkins PB, Kaplowitz N, Slattery JT, et al. Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily-A randomized controlled trial. Jama-J Am Med Assoc 2006; 296: 87-93.
-
(2006)
Jama-J Am Med Assoc
, vol.296
, pp. 87-93
-
-
Watkins, P.B.1
Kaplowitz, N.2
Slattery, J.T.3
-
72
-
-
77953811759
-
Use of pharmacometabonomics for early prediction of acetaminopheninduced hepatotoxicity in humans
-
Winnike JH, Li Z, Wright FA, et al. Use of pharmacometabonomics for early prediction of acetaminopheninduced hepatotoxicity in humans. Clin Pharmacol Ther 2010; 88: 45-51.
-
(2010)
Clin Pharmacol Ther
, vol.88
, pp. 45-51
-
-
Winnike, J.H.1
Li, Z.2
Wright, F.A.3
-
73
-
-
77952091681
-
Lipidomic analysis of variation in response to simvastatin in the Cholesterol and Pharmacogenetics Study
-
Kaddurah-Daouk R, Baillie RA, Zhu HJ, et al. Lipidomic analysis of variation in response to simvastatin in the Cholesterol and Pharmacogenetics Study. Metabolomics 2010; 6: 191-201.
-
(2010)
Metabolomics
, vol.6
, pp. 191-201
-
-
Kaddurah-Daouk, R.1
Baillie, R.A.2
Zhu, H.J.3
-
74
-
-
80054059835
-
Enteric microbiome metabolites correlate with response to simvastatin treatment
-
Kaddurah-Daouk R, Baillie RA, Zhu H, et al. Enteric microbiome metabolites correlate with response to simvastatin treatment. PLoS One 2011; 6: e25482.
-
(2011)
PLoS One
, vol.6
-
-
Kaddurah-Daouk, R.1
Baillie, R.A.2
Zhu, H.3
-
75
-
-
84863617024
-
Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment
-
Trupp M, Zhu H, Wikoff WR, et al. Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment. PLoS One 2012; 7: e38386.
-
(2012)
PLoS One
, vol.7
-
-
Trupp, M.1
Zhu, H.2
Wikoff, W.R.3
-
76
-
-
78650513748
-
Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: Pharmacometabolomics-informed pharmacogenomics
-
Ji Y, Hebbring S, Zhu H, et al. Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics. Clin Pharmacol Ther 2011; 89: 97-104.
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 97-104
-
-
Ji, Y.1
Hebbring, S.2
Zhu, H.3
-
77
-
-
84863413686
-
Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: Selective serotonin reuptake inhibitor response pharmacogenomics
-
Abo R, Hebbring S, Ji Y, et al. Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics. Pharmacogenet Genomics 2012; 22: 247-253.
-
(2012)
Pharmacogenet Genomics
, vol.22
, pp. 247-253
-
-
Abo, R.1
Hebbring, S.2
Ji, Y.3
-
78
-
-
79960775080
-
Pretreatment metabotype as a predictor of response to sertraline or placebo in depressed outpatients: A proof of concept
-
Kaddurah-Daouk R, Boyle SH, Matson W, et al. Pretreatment metabotype as a predictor of response to sertraline or placebo in depressed outpatients: a proof of concept. Transl Psychiatry 2011; 1: 1-7.
-
(2011)
Transl Psychiatry
, vol.1
, pp. 1-7
-
-
Kaddurah-Daouk, R.1
Boyle, S.H.2
Matson, W.3
-
80
-
-
79958813560
-
3-Hydroxykynurenine and clinical symptoms in firstepisode neuroleptic-naive patients with schizophrenia
-
Condray R, Dougherty GG, Keshavan MS, et al. 3-Hydroxykynurenine and clinical symptoms in firstepisode neuroleptic-naive patients with schizophrenia. Int J Neuropsychopharmacolog 2011; 14: 756-767.
-
(2011)
Int J Neuropsychopharmacolog
, vol.14
, pp. 756-767
-
-
Condray, R.1
Dougherty, G.G.2
Keshavan, M.S.3
-
81
-
-
79955510058
-
Pharmacometabonomic profiling as a predictor of toxicity in patients with inoperable colorectal cancer treated with capecitabine
-
Backshall A, Sharma R, Clarke SJ, et al. Pharmacometabonomic profiling as a predictor of toxicity in patients with inoperable colorectal cancer treated with capecitabine. Clin Cancer Res 2011; 17: 3019-3028.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 3019-3028
-
-
Backshall, A.1
Sharma, R.2
Clarke, S.J.3
-
82
-
-
84874875065
-
Pharmacometabolomics reveals racial differences in response to atenolol treatment
-
Wikoff WR, Frye RF, Zhu H, et al. Pharmacometabolomics reveals racial differences in response to atenolol treatment. PLoS One 2013; 8: e57639.
-
(2013)
PLoS One
, vol.8
-
-
Wikoff, W.R.1
Frye, R.F.2
Zhu, H.3
-
83
-
-
78650434645
-
Pharmacometabonomics as an effector for personalized medicine
-
Nicholson JK, Wilson ID and Lindon JC. Pharmacometabonomics as an effector for personalized medicine. Pharmacogenomics 2011; 12: 103-111.
-
(2011)
Pharmacogenomics
, vol.12
, pp. 103-111
-
-
Nicholson, J.K.1
Wilson, I.D.2
Lindon, J.C.3
-
84
-
-
41149099000
-
Symbiotic gut microbes modulate human metabolic phenotypes
-
Li M, Wang B, Zhang M, et al. Symbiotic gut microbes modulate human metabolic phenotypes. Proc Natl Acad Sci USA 2008; 105: 2117-2122.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2117-2122
-
-
Li, M.1
Wang, B.2
Zhang, M.3
-
85
-
-
84858631197
-
Pharmacometabolomics: An emerging "omics" tool for the personalization of anticancer treatments and identification of new valuable therapeutic targets
-
Corona G, Rizzolio F, Giordano A, et al. Pharmacometabolomics: an emerging "omics" tool for the personalization of anticancer treatments and identification of new valuable therapeutic targets. J Cell Physiol 2012; 227: 2827-2831.
-
(2012)
J Cell Physiol
, vol.227
, pp. 2827-2831
-
-
Corona, G.1
Rizzolio, F.2
Giordano, A.3
-
86
-
-
84857099651
-
Putting the efficacy of psychiatric and general medicine medication into perspective: Review of meta-analyses
-
Leucht S, Hierl S, Kissling W, et al. Putting the efficacy of psychiatric and general medicine medication into perspective: review of meta-analyses. Br J Psychiatry 2012; 200: 97-106.
-
(2012)
Br J Psychiatry
, vol.200
, pp. 97-106
-
-
Leucht, S.1
Hierl, S.2
Kissling, W.3
-
87
-
-
35248878864
-
The withdrawal of torcetrapib from drug development: Implications for the future of drugs that alter HDL metabolism
-
Howes LG and Kostner K. The withdrawal of torcetrapib from drug development: implications for the future of drugs that alter HDL metabolism. Expert Opin Invest Drugs 2007; 16: 1509-1516.
-
(2007)
Expert Opin Invest Drugs
, vol.16
, pp. 1509-1516
-
-
Howes, L.G.1
Kostner, K.2
-
89
-
-
84861870849
-
Personalised medicine: Not just in our genes
-
Kitsios GD and Kent DM. Personalised medicine: not just in our genes. Br Med J 2012; 344: e2161.
-
(2012)
Br Med J
, vol.344
-
-
Kitsios, G.D.1
Kent, D.M.2
-
90
-
-
84867723916
-
The human gut microbiome: The ghost in the machine
-
Feeney A and Sleator RD. The human gut microbiome: the ghost in the machine. Future Microbiol 2012; 7: 1235-1237.
-
(2012)
Future Microbiol
, vol.7
, pp. 1235-1237
-
-
Feeney, A.1
Sleator, R.D.2
-
91
-
-
79959894418
-
Understanding the role of gut microbiome-host metabolic signal disruption in health and disease
-
Holmes E, Li JV, Athanasiou T, et al. Understanding the role of gut microbiome-host metabolic signal disruption in health and disease. Trends Microbiol 2011; 19: 349-359.
-
(2011)
Trends Microbiol
, vol.19
, pp. 349-359
-
-
Holmes, E.1
Li, J.V.2
Athanasiou, T.3
-
92
-
-
84862276328
-
Structure, function and diversity of the healthy human microbiome
-
Huttenhower C, Gevers D, Knight R, et al. Structure, function and diversity of the healthy human microbiome. Nature 2012; 486: 207-214.
-
(2012)
Nature
, vol.486
, pp. 207-214
-
-
Huttenhower, C.1
Gevers, D.2
Knight, R.3
-
93
-
-
52049122412
-
The human gut microbiome: Implications for future health care
-
Kinross JM, von Roon AC, Holmes E, et al. The human gut microbiome: implications for future health care. Curr Gastroenterol Rep 2008; 10: 396-403.
-
(2008)
Curr Gastroenterol Rep
, vol.10
, pp. 396-403
-
-
Kinross, J.M.1
von Roon, A.C.2
Holmes, E.3
-
94
-
-
67650596799
-
The gut microbiota as a target for improved surgical outcome and improved patient care
-
Kinross J, von Roon AC, Penney N, et al. The gut microbiota as a target for improved surgical outcome and improved patient care. Curr Pharm Des 2009; 15: 1537-1545.
-
(2009)
Curr Pharm Des
, vol.15
, pp. 1537-1545
-
-
Kinross, J.1
von Roon, A.C.2
Penney, N.3
-
95
-
-
79952712983
-
Gut microbiome-host interactions in health and disease
-
Kinross JM, Darzi AW and Nicholson JK. Gut microbiome-host interactions in health and disease. Genome Med 2011; 3: 14.
-
(2011)
Genome Med
, vol.3
, pp. 14
-
-
Kinross, J.M.1
Darzi, A.W.2
Nicholson, J.K.3
-
96
-
-
84862286169
-
A framework for human microbiome research
-
Methe BA, Nelson KE, Pop M, et al. A framework for human microbiome research. Nature 2012; 486: 215-221.
-
(2012)
Nature
, vol.486
, pp. 215-221
-
-
Methe, B.A.1
Nelson, K.E.2
Pop, M.3
-
97
-
-
84856120472
-
Longitudinal pharmacometabonomics for predicting patient responses to therapy: Drug metabolism, toxicity and efficacy
-
Nicholson JK, Everett JR and Lindon JC. Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opin Drug Metab Toxicol 2012; 8: 135-139.
-
(2012)
Expert Opin Drug Metab Toxicol
, vol.8
, pp. 135-139
-
-
Nicholson, J.K.1
Everett, J.R.2
Lindon, J.C.3
-
98
-
-
36348990835
-
Human metabolic phenotypes link directly to specific dietary preferences in healthy individuals
-
Rezzi S, Ramadan Z, Martin FP, et al. Human metabolic phenotypes link directly to specific dietary preferences in healthy individuals. J Proteome Res 2007; 6: 4469-4477.
-
(2007)
J Proteome Res
, vol.6
, pp. 4469-4477
-
-
Rezzi, S.1
Ramadan, Z.2
Martin, F.P.3
-
99
-
-
84862141704
-
Human gut microbiome viewed across age and geography
-
Yatsunenko T, Rey FE, Manary MJ, et al. Human gut microbiome viewed across age and geography. Nature 2012; 486: 222-228.
-
(2012)
Nature
, vol.486
, pp. 222-228
-
-
Yatsunenko, T.1
Rey, F.E.2
Manary, M.J.3
-
100
-
-
84863631240
-
Targeting the human genome-microbiome axis for drug discovery: Inspirations from global systems biology and traditional Chinese medicine
-
Zhao L, Nicholson JK, Lu A, et al. Targeting the human genome-microbiome axis for drug discovery: inspirations from global systems biology and traditional Chinese medicine. J Proteome Res 2012; 11: 3509-3519.
-
(2012)
J Proteome Res
, vol.11
, pp. 3509-3519
-
-
Zhao, L.1
Nicholson, J.K.2
Lu, A.3
-
101
-
-
82755184864
-
The footprints of gut microbial-mammalian co-metabolism
-
Zheng X, Xie G, Zhao A, et al. The footprints of gut microbial-mammalian co-metabolism. J Proteome Res 2011; 10: 5512-5522.
-
(2011)
J Proteome Res
, vol.10
, pp. 5512-5522
-
-
Zheng, X.1
Xie, G.2
Zhao, A.3
-
102
-
-
84871732071
-
Genomic variation landscape of the human gut microbiome
-
Schloissnig S, Arumugam M, Sunagawa S, et al. Genomic variation landscape of the human gut microbiome. Nature 2013; 493: 45-50.
-
(2013)
Nature
, vol.493
, pp. 45-50
-
-
Schloissnig, S.1
Arumugam, M.2
Sunagawa, S.3
-
103
-
-
84867012919
-
Novel biomarkers for pre-diabetes identified by metabolomics
-
Wang-Sattler R, Yu Z, Herder C, et al. Novel biomarkers for pre-diabetes identified by metabolomics. Mol Syst Biol 2012; 8: 615.
-
(2012)
Mol Syst Biol
, vol.8
, pp. 615
-
-
Wang-Sattler, R.1
Yu, Z.2
Herder, C.3
-
104
-
-
79957857701
-
Metabolic phenotyping for monitoring surgical patients
-
Kinross JM, Holmes E, Darzi AW, et al. Metabolic phenotyping for monitoring surgical patients. Lancet 2011; 377: 1817-1819.
-
(2011)
Lancet
, vol.377
, pp. 1817-1819
-
-
Kinross, J.M.1
Holmes, E.2
Darzi, A.W.3
-
105
-
-
81855194269
-
Characterization of surgical aerosols by the compact single-particle mass spectrometer LAMPAS 3
-
Hinz KP, Gelhausen E, Schaefer KC, et al. Characterization of surgical aerosols by the compact single-particle mass spectrometer LAMPAS 3. Anal Bioanal Chem 2011; 401: 3165-3172.
-
(2011)
Anal Bioanal Chem
, vol.401
, pp. 3165-3172
-
-
Hinz, K.P.1
Gelhausen, E.2
Schaefer, K.C.3
-
106
-
-
79952143850
-
In situ, real-time identification of biological tissues by ultraviolet and infrared laser desorption ionization mass spectrometry
-
Schaefer K-C, Szaniszlo T, Guenther S, et al. In situ, real-time identification of biological tissues by ultraviolet and infrared laser desorption ionization mass spectrometry. Anal Chem 2011; 83: 1632-1640.
-
(2011)
Anal Chem
, vol.83
, pp. 1632-1640
-
-
Schaefer, K.-C.1
Szaniszlo, T.2
Guenther, S.3
-
107
-
-
84869049715
-
Metabolic phenotyping in clinical and surgical environments
-
Nicholson JK, Holmes E, Kinross JM, et al. Metabolic phenotyping in clinical and surgical environments. Nature 2012; 491: 384-392.
-
(2012)
Nature
, vol.491
, pp. 384-392
-
-
Nicholson, J.K.1
Holmes, E.2
Kinross, J.M.3
-
108
-
-
84859920644
-
Implementation of molecular phenotyping approaches in the personalized surgical patient journey
-
Mirnezami R, Kinross JM, Vorkas PA, et al. Implementation of molecular phenotyping approaches in the personalized surgical patient journey. Ann Surg 2012; 255: 881-889.
-
(2012)
Ann Surg
, vol.255
, pp. 881-889
-
-
Mirnezami, R.1
Kinross, J.M.2
Vorkas, P.A.3
-
109
-
-
84874622172
-
Metabolomics as a tool for personalizing medicine: 2012 update
-
Sun J, Beger RD and Schnackenberg LK. Metabolomics as a tool for personalizing medicine: 2012 update. Personal Med 2013; 10: 149-161.
-
(2013)
Personal Med
, vol.10
, pp. 149-161
-
-
Sun, J.1
Beger, R.D.2
Schnackenberg, L.K.3
-
110
-
-
0015136739
-
Metabolic oxidation on aliphatic basic nitrogen atoms and their alpha-carbon atomssome unifying principles
-
Beckett AH, van Dyk JM, Chissick HH, et al. Metabolic oxidation on aliphatic basic nitrogen atoms and their alpha-carbon atomssome unifying principles. J Pharm Pharmacol 1971; 23: 809-812.
-
(1971)
J Pharm Pharmacol
, vol.23
, pp. 809-812
-
-
Beckett, A.H.1
van Dyk, J.M.2
Chissick, H.H.3
-
111
-
-
0032168794
-
Systematic functional analysis of the yeast genome
-
Oliver SG, Winson MK, Kell DB, et al. Systematic functional analysis of the yeast genome. Trends Biotechnol 1998; 16: 373-378.
-
(1998)
Trends Biotechnol
, vol.16
, pp. 373-378
-
-
Oliver, S.G.1
Winson, M.K.2
Kell, D.B.3
-
112
-
-
0043069547
-
Opinion: Understanding 'global' systems biology: Metabonomics and the continuum of metabolism
-
Nicholson JK and Wilson ID. Opinion: understanding 'global' systems biology: metabonomics and the continuum of metabolism. Nat Rev Drug Discov 2003; 2: 668-676.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 668-676
-
-
Nicholson, J.K.1
Wilson, I.D.2
-
113
-
-
9244226956
-
Role of pharmacoproteomics in the development of personalized medicine
-
Jain KK. Role of pharmacoproteomics in the development of personalized medicine. Pharmacogenomics 2004; 5: 331-336.
-
(2004)
Pharmacogenomics
, vol.5
, pp. 331-336
-
-
Jain, K.K.1
|