3-Ketone-4,6-diene ceramide analogs exclusively induce apoptosis in chemo-resistant cancer cells

Bioorganic and Medicinal Chemistry

Volumn 22, Issue 4, 2014, Pages 1412-1420

  Ponnapakam, Adharsh P ^a   Liu, Jiawang ^b   Bhinge, Kaustubh N ^c   Drew, Barbara A ^a   Wang, Tony L ^a   Antoon, James W ^a   Nguyen, Thong T ^b   Dupart, Patrick S ^b   Wang, Yuji ^d   Zhao, Ming ^d   Liu, Yong Yu ^c   Foroozesh, Maryam ^b   Beckman, Barbara S ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b XAVIER UNIVERSITY OF LOUISIANA   (United States)

^c UNIVERSITY OF LOUISIANA AT MONROE   (United States)

^d CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Anti cancer drugs; Ceramide; Glucosylceramide synthase (GCS); Multidrug resistance; P glycoprotein

Indexed keywords

ANTI-CANCER DRUGS; CERAMIDE; GLUCOSYLCERAMIDE SYNTHASE (GCS); MULTIDRUG RESISTANCE; P-GLYCOPROTEIN;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZENEACETAMIDES; CELL LINE, TUMOR; CERAMIDES; DRUG RESISTANCE, NEOPLASM; GLUCOSYLTRANSFERASES; HUMANS; ISOMERISM; KETONES; MCF-7 CELLS; MOLECULAR CONFORMATION;

EID: 84893762538     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.12.065     Document Type: Article

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