Ceramide glycosylation by glucosylceramide synthase selectively maintains the properties of breast cancer stem cells

Journal of Biological Chemistry

Volumn 287, Issue 44, 2012, Pages 37195-37205

  Gupta, Vineet ^a   Bhinge, Kaustubh N ^a   Hosain, Salman B ^a   Xiong, Katherine ^a   Gu, Xin ^b   Shi, Runhua ^c   Ho, Ming Yi ^d   Khoo, Kay Hooi ^c   Li, Su Chen ^e   Li, Yu Teh ^e   Ambudkar, Suresh V ^e   Jazwinski, S Michal ^f   Liu, Yong Yu ^a  

^a UNIVERSITY OF LOUISIANA AT MONROE   (United States)

^b Louisiana State University School of Medicine Shreveport   (United States)

^c LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^d INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^e TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER; CANCER STEM CELLS; CERAMIDES; GLUCOSYLCERAMIDE SYNTHASE; GLYCOSPHINGOLIPIDS; STEM CELL FACTOR;

AMIDES; CELL MEMBRANES; CYTOLOGY; DISEASES; ESTERIFICATION; GLYCOSYLATION;

STEM CELLS;

BETA CATENIN; CD24 ANTIGEN; CERAMIDE; CERAMIDE DERIVATIVE; CERAMIDE GLUCOSYLTRANSFERASE; FIBROBLAST GROWTH FACTOR 2; GLOBOTRIOSYLCERAMIDE; HERMES ANTIGEN; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER STEM CELL; CARCINOGENESIS; CELL SELECTION; CONTROLLED STUDY; CORRELATIONAL STUDY; GENE SILENCING; GLYCOSYLATION; HUMAN; HUMAN CELL; LIPOGENESIS; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIGENS, CD24; ANTIGENS, CD44; BETA CATENIN; BREAST NEOPLASMS; CELL SEPARATION; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; CERAMIDES; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; FEMALE; GLUCOSYLTRANSFERASES; GLYCOSYLATION; HUMANS; IMMUNOMAGNETIC SEPARATION; MCF-7 CELLS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SIGNAL TRANSDUCTION; SPHEROIDS, CELLULAR;

EID: 84868232791     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.396390     Document Type: Article

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