Contribution of RhoA/Rho-kinase/MEK1/ERK1/2/iNOS pathway to ischemia/reperfusion-induced oxidative/nitrosative stress and inflammation leading to distant and target organ injury in rats

European Journal of Pharmacology

Volumn 723, Issue 1, 2014, Pages 234-245

  Sari, A Nihal ^a   Kacan, Meltem ^a   Unsal, Demet ^a   Sahan Firat, Seyhan ^a   Kemal Buharalioglu, C ^a   Vezir, Ozden ^a   Korkmaz, Belma ^a   Cuez, Tuba ^a   Canacankatan, Necmiye ^a   Sucu, Nehir ^a   Ayaz, Lokman ^a   Tamer Gumus, Lulufer ^a   Gorur, Aysegul ^a   Tunctan, Bahar ^a  

^a MERSIN UNIVERSITY   (Turkey)

Author keywords

Ischemia reperfusion; MEK1 ERK1 2 iNOS; Nitrosative stress; Oxidative stress; RhoA Rho kinase

Indexed keywords

ISCHEMIA/REPERFUSION; MEK1/ERK1/2/INOS; NITROSATIVE STRESS; OXIDATIVE STRESS; RHOA/RHO-KINASE;

AMIDES; ANIMALS; CATALASE; GLUTATHIONE; INFLAMMATION; KIDNEY; MALE; MALONDIALDEHYDE; MAP KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MUSCLE, SKELETAL; NADPH OXIDASE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PEROXIDASE; PEROXYNITROUS ACID; PYRIDINES; RATS; RATS, WISTAR; REPERFUSION INJURY; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SUPEROXIDE DISMUTASE; TYROSINE;

EID: 84893761855     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.11.027     Document Type: Article

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