Inhibition of renal Rho kinase attenuates ischemia/reperfusion-induced injury

Journal of the American Society of Nephrology

Volumn 19, Issue 11, 2008, Pages 2086-2097

  Prakash, Jai ^a   De Borst, Martin H ^b   Lacombe, Marie ^c   Opdam, Frank ^c   Klok, Pieter A ^b   Van Goor, Harry ^b   Meijer, Dirk K F ^a   Moolenaar, Frits ^a   Poelstra, Klaas ^a   Kok, Robbert J ^a,d  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c Kreatech Biotechnology BV   (Netherlands)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; FIBRONECTIN; LYSOZYME; LZM; METALLOPROTEINASE; PROCOLLAGEN; RHO KINASE; SYNAPSIN I; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; ACTIN; AMIDE; CCL2 PROTEIN, RAT; CELL ADHESION MOLECULE; COLLAGEN TYPE I, ALPHA 1 CHAIN; DRUG CARRIER; HAVCR1PROTEIN, RAT; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN KINASE INHIBITOR; PYRIDINE DERIVATIVE; SMOOTH MUSCLE ACTIN, RAT; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; CELL INFILTRATION; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CONJUGATION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME INHIBITION; FIBROGENESIS; GENE EXPRESSION REGULATION; GLOMERULUS; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; INFLAMMATION; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY TUBULE ABSORPTION; KIDNEY TUBULE CELL; KIDNEY TUBULE DISORDER; LEUKOPENIA; MACROPHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; REPERFUSION INJURY; SINGLE DRUG DOSE; TARGET ORGAN; TISSUE DIFFERENTIATION; ANIMAL; DRUG ANTAGONISM; ENZYMOLOGY; GENE EXPRESSION; GENETICS; INJURY; KIDNEY; METABOLISM; PATHOLOGY; VASCULARIZATION; WISTAR RAT;

ACTINS; AMIDES; ANIMALS; CELL ADHESION MOLECULES; CHEMOKINE CCL2; COLLAGEN TYPE I; DRUG CARRIERS; GENE EXPRESSION; KIDNEY; MALE; MURAMIDASE; PROTEIN KINASE INHIBITORS; PYRIDINES; RATS; RATS, WISTAR; REPERFUSION INJURY; RHO-ASSOCIATED KINASES; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TRANSFORMING GROWTH FACTOR BETA1;

EID: 55749097408     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2007070794     Document Type: Article

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