-
3
-
-
0000342402
-
Neuroprotective effect of the free-radical scavenger MCI-186 in patients with cerebral infarction: Clinical evaluation using magnetic resonance imaging and spectroscopy
-
Houkin K., Nakayama N., Kamada K., Noujou T., Abe H., Kashiwaba T. Neuroprotective effect of the free-radical scavenger MCI-186 in patients with cerebral infarction Clinical evaluation using magnetic resonance imaging and spectroscopy. J. Stroke Cerebrovasc. Dis. 7:1998;315
-
(1998)
J. Stroke Cerebrovasc. Dis.
, vol.7
, pp. 315
-
-
Houkin, K.1
Nakayama, N.2
Kamada, K.3
Noujou, T.4
Abe, H.5
Kashiwaba, T.6
-
4
-
-
0031665161
-
Clinical efficacy of free-radical scavenger MCI-186 on acute cerebral infarction: Early phase II clinical trial
-
Otomo E., Tohgi H., Kogure K., Hirai S., Terashi A., Gotoh F., Tazaki Y., Ito E., Sawada T., Kobayashi S., Fujishima M., Nakashima M. Clinical efficacy of free-radical scavenger MCI-186 on acute cerebral infarction Early phase II clinical trial. Ther. Res. 19:1998;531
-
(1998)
Ther. Res.
, vol.19
, pp. 531
-
-
Otomo, E.1
Tohgi, H.2
Kogure, K.3
Hirai, S.4
Terashi, A.5
Gotoh, F.6
Tazaki, Y.7
Ito, E.8
Sawada, T.9
Kobayashi, S.10
Fujishima, M.11
Nakashima, M.12
-
5
-
-
0034730419
-
MCI-186: Further histochemical and biochemical evidence of neuroprotection
-
Wu T.W., Zeng L.H., Wu J., Fung K.P. MCI-186 further histochemical and biochemical evidence of neuroprotection. Life Sci. 67:2000;2387
-
(2000)
Life Sci.
, vol.67
, pp. 2387
-
-
Wu, T.W.1
Zeng, L.H.2
Wu, J.3
Fung, K.P.4
-
6
-
-
3042566457
-
Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters
-
Edaravone Acute Infarction Study Group. Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters. Cerebrovasc. Dis. 222:2003;1-5
-
(2003)
Cerebrovasc. Dis.
, vol.222
, pp. 1-5
-
-
-
8
-
-
0026655704
-
In vitro studies on the influence of L-ascorbic acid 2-[3, 4-dihydro- 2, 5, 7, 8-tetramethyl-2-(4, 8, 12-trimethyltridecyl)-2H-1-benzopyran-6yl-hydrogen phosphate] potassium salt on lipid peroxidation and phospholipase A2 activity
-
Kuribayashi Y., Yoshida K., Sakaue T., Okumura A. In vitro studies on the influence of L-ascorbic acid 2-[3, 4-dihydro- 2, 5, 7, 8-tetramethyl-2-(4, 8, 12-trimethyltridecyl)-2H-1-benzopyran-6yl-hydrogen phosphate] potassium salt on lipid peroxidation and phospholipase A2 activity. Arzneimittelforschung. 42:1992;1072
-
(1992)
Arzneimittelforschung
, vol.42
, pp. 1072
-
-
Kuribayashi, Y.1
Yoshida, K.2
Sakaue, T.3
Okumura, A.4
-
9
-
-
0032946329
-
Reduced reperfusion injury in muscle. A comparison of the timing of EPC-K1 administration in rats
-
Hirose J., Yamaga M., Takagi K. Reduced reperfusion injury in muscle. A comparison of the timing of EPC-K1 administration in rats. Acta Orthop. Scand. 70:1999;207
-
(1999)
Acta Orthop. Scand.
, vol.70
, pp. 207
-
-
Hirose, J.1
Yamaga, M.2
Takagi, K.3
-
10
-
-
0034855855
-
Effects of a hydroxyl radical scavenger, EPC-K1, and neutrophil depletion on reperfusion injury in rat skeletal muscle
-
Hirose J., Yamaga M., Kato T., Ikebe K., Takagi K. Effects of a hydroxyl radical scavenger, EPC-K1, and neutrophil depletion on reperfusion injury in rat skeletal muscle. Acta Orthop. Scand. 72:2001;404
-
(2001)
Acta Orthop. Scand.
, vol.72
, pp. 404
-
-
Hirose, J.1
Yamaga, M.2
Kato, T.3
Ikebe, K.4
Takagi, K.5
-
11
-
-
0032853783
-
The role of glutamine in skeletal muscle ischemia/reperfusion injury in the rat hind limb model
-
Prem J.T., Eppinger M., Lemmon G., Miller S., Nolan D., Peoples J. The role of glutamine in skeletal muscle ischemia/reperfusion injury in the rat hind limb model. Am. J. Surg. 178:1999;147
-
(1999)
Am. J. Surg.
, vol.178
, pp. 147
-
-
Prem, J.T.1
Eppinger, M.2
Lemmon, G.3
Miller, S.4
Nolan, D.5
Peoples, J.6
-
12
-
-
0031773164
-
Reactions of N-methyl-2-phenylindole with malondialdehyde and 4-hydroxyalkenals. Mechanistic aspects of the colorimetric assay of lipid peroxidation
-
Erdelmeier I., Gerard-Monnier D., Yadan J.C., Chaudiere J. Reactions of N-methyl-2-phenylindole with malondialdehyde and 4-hydroxyalkenals. Mechanistic aspects of the colorimetric assay of lipid peroxidation. Chem. Res. Toxicol. 11:1998;1184
-
(1998)
Chem. Res. Toxicol.
, vol.11
, pp. 1184
-
-
Erdelmeier, I.1
Gerard-Monnier, D.2
Yadan, J.C.3
Chaudiere, J.4
-
13
-
-
0022397588
-
Myeloperoxidase activity as a quantitative marker of polymorphonuclear leukocyte accumulation into an experimental myocardial infarct: The effect of ibuprofen on infarct size and polymorphonuclear leukocyte accumulation
-
Allan G., Bhattacherjee P., Brook C.D., Read N.G., Parke A.J. Myeloperoxidase activity as a quantitative marker of polymorphonuclear leukocyte accumulation into an experimental myocardial infarct The effect of ibuprofen on infarct size and polymorphonuclear leukocyte accumulation. J. Cardiovasc. Pharmacol. 7:1985;1154
-
(1985)
J. Cardiovasc. Pharmacol.
, vol.7
, pp. 1154
-
-
Allan, G.1
Bhattacherjee, P.2
Brook, C.D.3
Read, N.G.4
Parke, A.J.5
-
14
-
-
0032029483
-
Effects of various doses of antithrombin III on endotoxin-induced endothelial cell injury and coagulation abnormalities in rats
-
Uchiba M., Okajima K., Murakami K. Effects of various doses of antithrombin III on endotoxin-induced endothelial cell injury and coagulation abnormalities in rats. Thromb. Res. 89:1998;233
-
(1998)
Thromb. Res.
, vol.89
, pp. 233
-
-
Uchiba, M.1
Okajima, K.2
Murakami, K.3
-
15
-
-
0028997918
-
Free gracilis muscle transplantation for hand reconstruction
-
Krimmer H., Hahn P., Lanz U. Free gracilis muscle transplantation for hand reconstruction. Clin. Orthop. 314:1995;13
-
(1995)
Clin. Orthop.
, vol.314
, pp. 13
-
-
Krimmer, H.1
Hahn, P.2
Lanz, U.3
-
16
-
-
0031974694
-
Free muscle transfer can restore hand function after injuries of the lower brachial plexus
-
Doi K., Hattori Y., Kuwata N., Soo-heong T., Kawakami F., Otsuka K., Watanabe M. Free muscle transfer can restore hand function after injuries of the lower brachial plexus. J. Bone Joint Surg. Br. 80:1998;117
-
(1998)
J. Bone Joint Surg. Br.
, vol.80
, pp. 117
-
-
Doi, K.1
Hattori, Y.2
Kuwata, N.3
Soo-Heong, T.4
Kawakami, F.5
Otsuka, K.6
Watanabe, M.7
-
17
-
-
0028559859
-
Present status of replantation in Japan
-
Fukui A., Tamai S. Present status of replantation in Japan. Microsurgery. 15:1994;842
-
(1994)
Microsurgery
, vol.15
, pp. 842
-
-
Fukui, A.1
Tamai, S.2
-
18
-
-
0031002835
-
Replantation and revascularization of the digits in a community microsurgical practice
-
Pomerance J., Truppa K., Bilos Z.J., Vender M.I., Ruder J.R., Sagerman S.D. Replantation and revascularization of the digits in a community microsurgical practice. J. Reconstr. Microsurg. 13:1997;163
-
(1997)
J. Reconstr. Microsurg.
, vol.13
, pp. 163
-
-
Pomerance, J.1
Truppa, K.2
Bilos, Z.J.3
Vender, M.I.4
Ruder, J.R.5
Sagerman, S.D.6
-
19
-
-
0018254967
-
Digit replantation. Analysis of 163 replantations in an 11-year period
-
Tamai S. Digit replantation. Analysis of 163 replantations in an 11-year period. Clin. Plast. Surg. 5:1978;195
-
(1978)
Clin. Plast. Surg.
, vol.5
, pp. 195
-
-
Tamai, S.1
-
20
-
-
0028307383
-
Evidence implicating xanthine oxidase and neutrophils in reperfusion-induced microvascular dysfunction
-
Kurose I., Granger D.N. Evidence implicating xanthine oxidase and neutrophils in reperfusion-induced microvascular dysfunction. Ann. N Y Acad. Sci. 723:1994;158
-
(1994)
Ann. N Y Acad. Sci.
, vol.723
, pp. 158
-
-
Kurose, I.1
Granger, D.N.2
-
21
-
-
0021265182
-
Damaging effects of oxygen radicals on resealed erythrocyte ghosts
-
Girotti A.W., Thomas J.P. Damaging effects of oxygen radicals on resealed erythrocyte ghosts. J. Biol. Chem. 259:1984;1744
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 1744
-
-
Girotti, A.W.1
Thomas, J.P.2
-
23
-
-
0032054483
-
Inhibitory effect of MCI-186, a free radical scavenger, on cerebral ischemia following rat middle cerebral artery occlusion
-
Mizuno A., Umemura K., Nakashima M. Inhibitory effect of MCI-186, a free radical scavenger, on cerebral ischemia following rat middle cerebral artery occlusion. Gen. Pharmacol. 30:1998;575
-
(1998)
Gen. Pharmacol.
, vol.30
, pp. 575
-
-
Mizuno, A.1
Umemura, K.2
Nakashima, M.3
-
24
-
-
0023947826
-
Strong attenuation of ischemic and postischemic brain edema in rats by a novel free-radical scavenger
-
Abe K., Yuki S., Kogure K. Strong attenuation of ischemic and postischemic brain edema in rats by a novel free-radical scavenger. Stroke. 19:1988;480
-
(1988)
Stroke
, vol.19
, pp. 480
-
-
Abe, K.1
Yuki, S.2
Kogure, K.3
-
25
-
-
0024414674
-
Effect of MCI-186 on brain edema in rats
-
Nishi H., Watanabe T., Sakurai H., Yuki S., Ishibashi A. Effect of MCI-186 on brain edema in rats. Stroke. 20:1989;1236
-
(1989)
Stroke
, vol.20
, pp. 1236
-
-
Nishi, H.1
Watanabe, T.2
Sakurai, H.3
Yuki, S.4
Ishibashi, A.5
-
26
-
-
0028292964
-
Protective effects of MCI-186 on cerebral ischemia: Possible involvement of free-radical scavenging and antioxidant actions
-
Watanabe T., Yuki S., Egawa M., Nishi H. Protective effects of MCI-186 on cerebral ischemia Possible involvement of free-radical scavenging and antioxidant actions. J. Pharmacol. Exp. Ther. 268:1994;1597
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.268
, pp. 1597
-
-
Watanabe, T.1
Yuki, S.2
Egawa, M.3
Nishi, H.4
-
27
-
-
0141519508
-
Edaravone, a novel free-radical scavenger, prevents liver injury and mortality in rats administered endotoxin
-
Kono H., Asakawa M., Fujii H., Maki A., Amemiya H., Yamamoto M., Matsuda M., Matsumoto Y. Edaravone, a novel free-radical scavenger, prevents liver injury and mortality in rats administered endotoxin. J. Pharmacol. Exp. Ther. 307:2003;74
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.307
, pp. 74
-
-
Kono, H.1
Asakawa, M.2
Fujii, H.3
Maki, A.4
Amemiya, H.5
Yamamoto, M.6
Matsuda, M.7
Matsumoto, Y.8
-
28
-
-
0141545082
-
A theoretical investigation on DPPH radical-scavenging mechanism of edaravone
-
Wang L.F., Zhang H.Y. A theoretical investigation on DPPH radical-scavenging mechanism of edaravone. Bioorg. Med. Chem. Lett. 13:2003;3789
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 3789
-
-
Wang, L.F.1
Zhang, H.Y.2
-
29
-
-
0032125643
-
Effect of EPC-K1 on myocardial infarct size in a rat model with coronary artery occlusion and reperfusion
-
Yamada S., Yashita T., Yamaguchi K., Kyuki K., Sakaue T., Ogata K. Effect of EPC-K1 on myocardial infarct size in a rat model with coronary artery occlusion and reperfusion. Gen. Pharmacol. 31:1998;165
-
(1998)
Gen. Pharmacol.
, vol.31
, pp. 165
-
-
Yamada, S.1
Yashita, T.2
Yamaguchi, K.3
Kyuki, K.4
Sakaue, T.5
Ogata, K.6
-
30
-
-
0030801031
-
Delayed neuronal death prevented by inhibition of increased hydroxyl radical formation in a transient cerebral ischemia
-
Yamamoto T., Yuki S., Watanabe T., Mitsuka M., Saito K.I., Kogure K. Delayed neuronal death prevented by inhibition of increased hydroxyl radical formation in a transient cerebral ischemia. Brain Res. 762:1997;240
-
(1997)
Brain Res.
, vol.762
, pp. 240
-
-
Yamamoto, T.1
Yuki, S.2
Watanabe, T.3
Mitsuka, M.4
Saito, K.I.5
Kogure, K.6
-
31
-
-
0021678625
-
Muscle fiber type composition of the rat hindlimb
-
Armstrong R.B., Phelps R.O. Muscle fiber type composition of the rat hindlimb. Am. J. Anat. 171:1984;259
-
(1984)
Am. J. Anat.
, vol.171
, pp. 259
-
-
Armstrong, R.B.1
Phelps, R.O.2
-
33
-
-
0031015329
-
Metabolic and contractile responses of fast- and slow-twitch rat skeletal muscles to ischemia and reperfusion
-
Carvalho A.J., McKee N.H., Green H.J. Metabolic and contractile responses of fast- and slow-twitch rat skeletal muscles to ischemia and reperfusion. Plast. Reconstr. Surg. 99:1997;163
-
(1997)
Plast. Reconstr. Surg.
, vol.99
, pp. 163
-
-
Carvalho, A.J.1
McKee, N.H.2
Green, H.J.3
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