Involvement of sphingosine 1-phosphate in palmitate-induced insulin resistance of hepatocytes via the S1P2 receptor subtype

Diabetologia

Volumn 57, Issue 2, 2014, Pages 373-382

  Fayyaz, Susann ^a   Henkel, Janin ^a   Japtok, Lukasz ^a   Krämer, Stephanie ^b   Damm, Georg ^c   Seehofer, Daniel ^c   Püschel, Gerhard P ^a   Kleuser, Burkhard ^a  

^a UNIVERSITY OF POTSDAM   (Germany)

^b GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

FTY720; Insulin signalling; Palmitate; S1P receptors; Sphingolipids; Sphingosine 1 phosphate

Indexed keywords

4 (2,6 DICHLORO 4 PYRIDINYL) 1 (1,3 DIMETHYL 4 ISOPROPYL 1H PYRAZOLO[3,4 B]PYRIDIN 6 YL)SEMICARBAZIDE; CERAMIDE; FINGOLIMOD PHOSPHATE; IMMUNOMODULATING AGENT; PALMITIC ACID; SATURATED FATTY ACID; SERINE; SPHINGOLIPID; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GLYCOGEN LIVER LEVEL; GLYCOGEN SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; LIPID DIET; LIVER CELL; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; BLOTTING, WESTERN; CHROMATOGRAPHY, LIQUID; DIABETES MELLITUS, TYPE 2; HEPATOCYTES; IMMUNOSUPPRESSIVE AGENTS; INSULIN; INSULIN RESISTANCE; LYSOPHOSPHOLIPIDS; MALE; MICE; MICE, OBESE; ORGANOPHOSPHATES; PALMITATES; RATS; RATS, WISTAR; SPHINGOSINE;

EID: 84893690338     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-3123-6     Document Type: Article

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