Activation of Pak1/Akt/eNOS signaling following sphingosine-1-phosphate release as part of a mechanism protecting cardiomyocytes against ischemic cell injury

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 301, Issue 4, 2011, Pages

  Egom, Emmanuel Eroume A ^a,b   Mohamed, Tamer M A ^b   Mamas, Mamas A ^b,e   Shi, Ying ^c   Liu, Wei ^b   Chirico, Debora ^e   Stringer, Sally E ^b   Ke, Yunbo ^d   Shaheen, Mohamed ^b   Wang, Tao ^b   Chacko, Sanoj ^e   Wang, Xin ^b   Solaro, R John ^d   Fath Ordoubadi, Farzin ^e   Cartwright, Elizabeth J ^b   Lei, Ming ^b  

^a UNIVERSITY OF HULL   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^d UNIVERSITY OF ILLINOIS   (United States)

^e MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

Endothelial nitric oxide synthase; FTY720; Ischemia; Long chain sphingoid base

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; FINGOLIMOD; LACTATE DEHYDROGENASE; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SPHINGOSINE 1 PHOSPHATE;

ADULT; AGED; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CELL DAMAGE; CELL VIABILITY; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORONARY SINUS; ENZYME ACTIVATION; ENZYME RELEASE; FEMORAL VEIN; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HUMAN; IN VITRO STUDY; ISCHEMIA; ISOLATED HEART; MOUSE; NONHUMAN; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPECTROPHOTOMETRY;

ADULT; AGED; ANGIOPLASTY, BALLOON, CORONARY; ANIMALS; ARRHYTHMIAS, CARDIAC; BIOTRANSFORMATION; BLOTTING, WESTERN; CARDIOTONIC AGENTS; CELL HYPOXIA; CELL SURVIVAL; CORONARY OCCLUSION; FEMALE; HUMANS; L-LACTATE DEHYDROGENASE; LYSOPHOSPHOLIPIDS; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; MYOCYTES, CARDIAC; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; ONCOGENE PROTEIN V-AKT; P21-ACTIVATED KINASES; PERTUSSIS TOXIN; PROPYLENE GLYCOLS; RATS; SPHINGOLIPIDS; SPHINGOSINE;

EID: 80053266443     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01003.2010     Document Type: Article

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