Oxidative stress increased hepatotoxicity induced by nano-titanium dioxide in BRL-3A cells and Sprague-Dawley rats

Journal of Applied Toxicology

Volumn 34, Issue 4, 2014, Pages 345-356

  Sha, Baoyong ^a,b   Gao, Wei ^b   Wang, Shuqi ^c   Gou, Xingchun ^a   Li, Wei ^d   Liang, Xuan ^e   Qu, Zhiguo ^b   Xu, Feng ^b   Lu, Tian Jian ^b  

^a XI'AN MEDICAL UNIVERSITY   (China)

^b XI'AN JIAOTONG UNIVERSITY   (China)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^e Gansu Provincial Second People's Hospital   (China)

Author keywords

Alloxan; Cell; Hydrogen peroxide; Nano titanium dioxide; Nanotoxicity; Rat

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ALLOXAN; ASPARTATE AMINOTRANSFERASE; GLUTATHIONE; HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; MALONALDEHYDE; NANOMATERIAL; SUPEROXIDE; SUPEROXIDE DISMUTASE; TITANIUM DIOXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE S PHASE; CELL VIABILITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; ELECTRON DIFFRACTION; G1 PHASE CELL CYCLE CHECKPOINT; G2 PHASE CELL CYCLE CHECKPOINT; LIVER INJURY; LIVER TOXICITY; M PHASE CELL CYCLE CHECKPOINT; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION; ZETA POTENTIAL;

RATTUS;

ALLOXAN; CELL; HYDROGEN PEROXIDE; NANO-TITANIUM DIOXIDE; NANOTOXICITY; RAT;

ALLOXAN; ANIMALS; CELL CULTURE TECHNIQUES; CELL LINE; CELL SURVIVAL; DRUG-INDUCED LIVER INJURY; HYDROGEN PEROXIDE; LIVER; MALE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; OXIDATIVE STRESS; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY; SURFACE PROPERTIES; TITANIUM;

EID: 84893663435     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.2900     Document Type: Article

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