Modulation of mitochondrial calcium management attenuates hepatic warm ischemia-reperfusion injury

Liver Transplantation

Volumn 11, Issue 6, 2005, Pages 663-668

  Anderson, Christopher D ^a   Pierce, Janene ^a   Nicoud, Ian ^b   Belous, Andrey ^a   Knox, Clayton D ^a   Chari, Ravi S ^a,b  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; EOSIN; HEMATOXYLIN; RUTHENIUM RED;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATTENUATION; CALCIUM TRANSPORT; CELL DEATH; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE ASSOCIATION; HISTOCHEMISTRY; HISTOPATHOLOGY; INHIBITION KINETICS; LIVER FAILURE; LIVER ISCHEMIA; LIVER NECROSIS; MALE; MITOCHONDRION; NICK END LABELING; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REPERFUSION INJURY; TIME; TISSUE SECTION;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL; CALCIUM; DISEASE MODELS, ANIMAL; ISCHEMIA; LIVER; LIVER CIRCULATION; MALE; NECROSIS; PROBABILITY; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION; REPERFUSION INJURY; RISK FACTORS; RUTHENIUM RED; SENSITIVITY AND SPECIFICITY;

EID: 21044434779     PISSN: 15276465     EISSN: None     Source Type: Journal    
DOI: 10.1002/lt.20407     Document Type: Article

References (45)

1. Lemasters JJ, Thurman RG. The many facets of reperfusion injury. Gastroenterology 1995;108:1317-1320.
2. Delva E, Camus Y, Nordlinger B, Hannoun L, Parc R, Deriaz H, et al. Vascular occlusions for liver resections. Operative management and tolerance to hepatic ischemia: 142 cases. Ann Surg 1989;209:211-218.
3. Huguet C, Gavelli A, Chieco PA, Bona S, Harb J, Joseph JM, et al. Liver ischemia for hepatic resection: where is the limit? Surgery 1992;111:251-259.
4. Clavien PA, Harvey PR, Strasberg SM. Preservation and reperfusion injuries in liver allografts. An overview and synthesis of current studies. Transplantation 1992;53:957-978.
5. Ploeg RJ, D'Alessandro AM, Knechtle SJ, Stegall MD, Pirsch JD, Hoffmann RM, et al. Risk factors for primary dysfunction after liver transplantation - a multivariate analysis. Transplantation 1993;55:807-813.
6. Clavien PA, Emond J, Vauthey JN, Belghiti J, Chari RS, Strasberg SM. Protection of the liver during hepatic surgery. J Gastrointest Surg 2004;8:313-327.
7. Selzner N, Rudiger H, Graf R, Clavien PA. Protective strategies against ischemic injury of the liver. Gastroenterology 2003;125: 917-936.
8. Serracino-Inglott F, Habib NA, Mathie RT. Hepatic ischemia-reperfusion injury. Am J Surg 2001;181:160-166.
9. Jaeschke H. Mechanisms of reperfusion injury after warm ischemia of the liver. J Hepatobiliary Pancreat Surg 1998;5:402-408.
10. Pozzan T, Magalhaes P, Rizzuto R. The comeback of mitochondria to calcium signalling. Cell Calcium 2000;28:279-283.
11. Rizzuto R, Bernardi P, Pozzan T. Mitochondria as all-round players of the calcium game. J Physiol 2000;529(Pt 1):37-47.
12. Parekh AB. Mitochondrial regulation of intracellular Ca2+ signaling: more than just simple Ca2+ bufers. News Physiol Sci 2003;18:252-256.
13. Orrenius S, Zhivotovsky B, Nicotera P. Regulation of cell death: the calcium-apoptosis link. Nat Rev Mol Cell Biol 2003;4:552-565.
14. Farber JL. The role of calcium in lethal cell injury. Chem Res Toxicol 1990;3:503-508.
15. Amberger A, Weiss H, Haller T, Kock G, Hermann M, Widschwendter M, Margreiter R. A subpopulation of mitochondria prevents cytosolic calcium overload in endothelial cells after cold ischemia/reperfusion. Transplantation 2001;71:1821-1827.
16. Crompton M. The mitochondrial permeability transition pore and its role in cell death. Biochem J 1999;341:233-249.
17. Kroemer G, Reed JC. Mitochondrial control of cell death. Nat Med 2000;6:513-519.
18. Ying WL, Emerson J, Clarke MJ, Sanadi DR. Inhibition of mitochondrial calcium ion transport by an oxo-bridged dinuclear ruthenium ammine complex. Biochemistry 1991;30: 4949-4952.
19. Litsky ML, Pfeiffer DR. Regulation of the mitochondrial Ca2+ uniporter by external adenine nucleotides: the uniporter behaves like a gated channel which is regulated by nucleotides and divalent cations. Biochemistry 1997;36:7071-7080.
20. Belous A, Knox C, Nicoud IB, Pierce J, Anderson C, Pinson CW, Chari RS. Reversed activity of mitochondrial adenine nucleotide translocator in ischemia-reperfusion. Transplantation 2003;75:1717-1723.
21. Belous A, Knox C, Nicoud IB, Pierce J, Anderson C, Pinson CW, Chari RS. Altered ATP-dependent mitochondrial Ca2+ uptake in cold ischemia is attenuated by ruthenium red. J Surg Res 2003;111:284-289.
22. Luthra R, Olson MS. The inhibition of calcium uptake and release by rat liver mitochondria by ruthenium red. FEBS Lett 1977;81:142-146.
23. Rossi CS, Vasington FD, Carafoli E. The efect of ruthenium red on the uptake and release of Ca 2+ by mitochondria. Biochem Biophys Res Commun 1973;50:846-852.
24. Tapia R, Velasco I. Ruthenium red as a tool to study calcium channels, neuronal death and the function of neural pathways. Neurochem Int 1997;30:137-147.
25. Benzi RH, Lerch R. Dissociation between contractile function and oxidative metabolism in postischemic myocardium. Attenuation by ruthenium red administered during reperfusion. Circ Res 1992;71:567-576.
26. Miyamae M, Camacho SA, Weiner MW, Figueredo VM. Attenuation of postischemic reperfusion injury is related to prevention of [Ca2+]m overload in rat hearts. Am J Physiol 1996;271: H2145-H2153.
27. Liang WY, Tang LX, Yang ZC, Huang YS. Calcium induced the damage of myocardial mitochondrial respiratory function in the early stage after severe burns. Burns 2002;28:143-146.
28. Anderson CD, Belous A, Pierce J, Nicoud IB, Knox C, Wakata A, et al. Mitochondrial calcium uptake regulates cold preservation-induced Bax translocation and early reperfusion apoptosis. Am J Transplant 2004;4:352-362.
29. Camargo CA, Jr., Madden JF, Gao W, Selvan RS, Clavien PA. Interleukin-6 protects liver against warm ischemia/reperfusion injury and promotes hepatocyte proliferation in the rodent. Hepatology 1997;26:1513-1520.
30. Iu S, Harvey PR, Makowka L, Petrunka CN, Ilson RG, Strasberg SM. Markers of allograft viability in the rat. Relationship between transplantation viability and liver function in the isolated perfused liver. Transplantation 1987;44:562-569.
31. Kohli V, Selzner M, Madden JF, Bentley RC, Clavien PA. Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver. Transplantation 1999; 67:1099-1105.
32. Cursio R, Gugenheim J, Ricci JE, Crenesse D, Rostagno P, Maulon L, et al. A caspase inhibitor fully protects rats against lethal normothermic liver ischemia by inhibition of liver apoptosis. FASEB J 1999;13:253-261.
33. Shimizu S, Eguchi Y, Kamiike W, Akao Y, Kosaka H, Hasegawa J, et al. Involvement of ICE family proteases in apoptosis induced by reoxygenation of hypoxic hepatocytes. Am J Physiol 1996; 271:G949-G958.
34. Clavien PA, Rudiger HA, Selzner M. Mechanism of hepatocyte death after ischemia: apoptosis versus necrosis. Hepatology 2001;33:1555-1557.
35. Gujral JS, Bucci TJ, Farhood A, Jaeschke H. Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis? Hepatology 2001;33:397-405.
36. Selzner M, Rudiger HA, Sindram D, Madden J, Clavien PA. Mechanisms of ischemic injury are different in the steatotic and normal rat liver. Hepatology 2000;32:1280-1288.
37. Lemasters JJ. V. Necrapoptosis and the mitochondrial permeability transition: shared pathways to necrosis and apoptosis. Am J Physiol 1999;276:G1-G6.
38. Lemasters JJ, Qian T, Bradham CA, Brenner DA, Cascio WE, Trost LC, et al. Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death. J Bioenerg Biomembr 1999; 31:305-319.
39. Rudiger HA, Clavien PA. Tumor necrosis factor alpha, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver. Gastroenterology 2002;122:202-210.
40. Selzner M, Rudiger HA, Selzner N, Thomas DW, Sindram D, Clavien PA. Transgenic mice overexpressing human Bcl-2 are resistant to hepatic ischemia and reperfusion. J Hepatol 2002; 36:218-225.
41. Green DR, Reed JC. Mitochondria and apoptosis. Science 1998; 281:1309-1312.
42. Mayer B, Oberbauer R. Mitochondrial regulation of apoptosis. News Physiol Sci 2003;18:89-94.
43. Belous AE, Wakata A, Knox C, Nicoud IB, Pierce J, Anderson CD, Chari RS. Mitochondrial P2Y-like receptors link cytosolic adenosine nucleotides to mitochondrial calcium uptake. J Cell Biochem 2004;94:1062-1073.
44. Qian T, Herman B, Lemasters JJ. The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187. Toxicol Appl Pharmacol 1999;154:117-125.
45. Tatsumi T, Shiraishi J, Keira N, Akashi K, Mano A, Yamanaka S, et al. Intracellular ATP is required for mitochondrial apoptotic pathways in isolated hypoxic rat cardiac myocytes. Cardiovasc Res 2003;59:428-440.