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Volumn 189, Issue 3, 2014, Pages 314-324

Regulation of hypoxia-induced pulmonary hypertension by vascular smooth muscle hypoxia-inducible factor-1α

Author keywords

Animal disease models; Knock out mice; Pulmonary circulation; Right ventricular hypertrophy

Indexed keywords

CRE RECOMBINASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; TAMOXIFEN;

EID: 84893555039     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201302-0302OC     Document Type: Article
Times cited : (228)

References (53)
  • 1
    • 24744462498 scopus 로고    scopus 로고
    • Pulmonary hypertension in interstitial lung disease
    • Strange C, Highland KB. Pulmonary hypertension in interstitial lung disease. Curr Opin Pulm Med 2005;11:452-455.
    • (2005) Curr Opin Pulm Med , vol.11 , pp. 452-455
    • Strange, C.1    Highland, K.B.2
  • 2
    • 32244435766 scopus 로고    scopus 로고
    • Secondary pulmonary hypertension
    • Roy R, Couriel JM. Secondary pulmonary hypertension. Paediatr Respir Rev 2006;7:36-44.
    • (2006) Paediatr Respir Rev , vol.7 , pp. 36-44
    • Roy, R.1    Couriel, J.M.2
  • 3
    • 15544380502 scopus 로고    scopus 로고
    • Lung vascular development: Implications for the pathogenesis of bronchopulmonary dysplasia
    • Stenmark KR, Abman SH. Lung vascular development: implications for the pathogenesis of bronchopulmonary dysplasia. Annu Rev Physiol 2005;67:623-661.
    • (2005) Annu Rev Physiol , vol.67 , pp. 623-661
    • Stenmark, K.R.1    Abman, S.H.2
  • 4
    • 17644406055 scopus 로고    scopus 로고
    • Pulmonary hypertension and right heart failure in chronic obstructive pulmonary disease
    • Naeije R. Pulmonary hypertension and right heart failure in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2005;2:20-22.
    • (2005) Proc Am Thorac Soc , vol.2 , pp. 20-22
    • Naeije, R.1
  • 5
    • 0018844674 scopus 로고
    • Heart failure in cystic fibrosis. Treatment and prognosis of cor pulmonale with failure of the right side of the heart
    • Stern RC, Borkat G, Hirschfeld SS, Boat TF, Matthews LW, Liebman J, Doershuk CF. Heart failure in cystic fibrosis. Treatment and prognosis of cor pulmonale with failure of the right side of the heart. Am J Dis Child 1980;134:267-272.
    • (1980) Am J Dis Child , vol.134 , pp. 267-272
    • Stern, R.C.1    Borkat, G.2    Hirschfeld, S.S.3    Boat, T.F.4    Matthews, L.W.5    Liebman, J.6    Doershuk, C.F.7
  • 6
    • 84876509337 scopus 로고    scopus 로고
    • Significant differences in markers of oxidant injury between idiopathic and bronchopulmonary-dysplasia-associated pulmonary hypertension in children
    • Vera KB, Moore D, Flack E, Liske M, Summar M. Significant differences in markers of oxidant injury between idiopathic and bronchopulmonary-dysplasia- associated pulmonary hypertension in children. Pulm Med 2012;2012:301475.
    • (2012) Pulm Med , vol.2012 , pp. 301475
    • Vera, K.B.1    Moore, D.2    Flack, E.3    Liske, M.4    Summar, M.5
  • 7
    • 36849067910 scopus 로고    scopus 로고
    • Pulmonary artery hypertension in formerly premature infants with bronchopulmonary dysplasia: Clinical features and outcomes in the surfactant era
    • Khemani E, McElhinney DB, Rhein L, Andrade O, Lacro RV, Thomas KC, Mullen MP. Pulmonary artery hypertension in formerly premature infants with bronchopulmonary dysplasia: clinical features and outcomes in the surfactant era. Pediatrics 2007;120:1260-1269.
    • (2007) Pediatrics , vol.120 , pp. 1260-1269
    • Khemani, E.1    McElhinney, D.B.2    Rhein, L.3    Andrade, O.4    Lacro, R.V.5    Thomas, K.C.6    Mullen, M.P.7
  • 8
    • 79951686318 scopus 로고    scopus 로고
    • Pulmonary hypertension in infants with bronchopulmonary dysplasia
    • Kim GB. Pulmonary hypertension in infants with bronchopulmonary dysplasia. Korean J Pediatr 2010;53:688-693.
    • (2010) Korean J Pediatr , vol.53 , pp. 688-693
    • Kim, G.B.1
  • 9
    • 0026075610 scopus 로고
    • Hypoxia-inducible nuclear factors bind to an enhancer element located 39 to the human erythropoietin gene
    • Semenza GL, Nejfelt MK, Chi SM, Antonarakis SE. Hypoxia-inducible nuclear factors bind to an enhancer element located 39 to the human erythropoietin gene. Proc Natl Acad Sci USA 1991;88:5680-5684.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5680-5684
    • Semenza, G.L.1    Nejfelt, M.K.2    Chi, S.M.3    Antonarakis, S.E.4
  • 15
    • 0031016301 scopus 로고    scopus 로고
    • Induction of hypoxia-inducible factor-1, erythropoietin, vascular endothelial growth factor, and glucose transporter-1 by hypoxia: Evidence against a regulatory role for Src kinase
    • Gleadle JM, Ratcliffe PJ. Induction of hypoxia-inducible factor-1, erythropoietin, vascular endothelial growth factor, and glucose transporter-1 by hypoxia: evidence against a regulatory role for Src kinase. Blood 1997;89:503-509.
    • (1997) Blood , vol.89 , pp. 503-509
    • Gleadle, J.M.1    Ratcliffe, P.J.2
  • 16
    • 33749345684 scopus 로고    scopus 로고
    • Hypoxia-induced pulmonary vascular remodeling: Cellular and molecular mechanisms
    • Stenmark KR, Fagan KA, Frid MG. Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms. Circ Res 2006;99:675-691.
    • (2006) Circ Res , vol.99 , pp. 675-691
    • Stenmark, K.R.1    Fagan, K.A.2    Frid, M.G.3
  • 17
    • 0035014370 scopus 로고    scopus 로고
    • Selected contribution: Pulmonary hypertension in mice following intermittent hypoxia
    • Fagan KA. Selected contribution: pulmonary hypertension in mice following intermittent hypoxia. J Appl Physiol (1985) 2001;90: 2502-2507.
    • (2001) J Appl Physiol (1985) , vol.90 , pp. 2502-2507
    • Fagan, K.A.1
  • 20
    • 0018824798 scopus 로고
    • Hypoxia-induced structural changes in the media and adventitia of the rat hilar pulmonary artery and their regression
    • Meyrick B, Reid L. Hypoxia-induced structural changes in the media and adventitia of the rat hilar pulmonary artery and their regression. Am J Pathol 1980;100:151-178.
    • (1980) Am J Pathol , vol.100 , pp. 151-178
    • Meyrick, B.1    Reid, L.2
  • 21
    • 0021351634 scopus 로고
    • Autoradiographic analysis of cell proliferation and protein synthesis in the pulmonary trunk of rats during the early development of hypoxia-induced pulmonary hypertension
    • McKenzie JC, Clancy J Jr, Klein RM. Autoradiographic analysis of cell proliferation and protein synthesis in the pulmonary trunk of rats during the early development of hypoxia-induced pulmonary hypertension. Blood Vessels 1984;21:80-89.
    • (1984) Blood Vessels , vol.21 , pp. 80-89
    • McKenzie, J.C.1    Clancy Jr., J.2    Klein, R.M.3
  • 22
    • 34547627296 scopus 로고    scopus 로고
    • The effects of hypoxia on the cells of the pulmonary vasculature
    • Pak O, Aldashev A, Welsh D, Peacock A. The effects of hypoxia on the cells of the pulmonary vasculature. Eur Respir J 2007;30:364-372.
    • (2007) Eur Respir J , vol.30 , pp. 364-372
    • Pak, O.1    Aldashev, A.2    Welsh, D.3    Peacock, A.4
  • 23
    • 33744944257 scopus 로고    scopus 로고
    • Hypoxia and hypoxia-inducible factor-1alpha promote growth factor-induced proliferation of human vascular smooth muscle cells
    • Schultz K, Fanburg BL, Beasley D. Hypoxia and hypoxia-inducible factor-1alpha promote growth factor-induced proliferation of human vascular smooth muscle cells. Am J Physiol Heart Circ Physiol 2006; 290:H2528-H2534.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Schultz, K.1    Fanburg, B.L.2    Beasley, D.3
  • 25
    • 0037154262 scopus 로고    scopus 로고
    • Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha
    • Kline DD, Peng YJ, Manalo DJ, Semenza GL, Prabhakar NR. Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha. Proc Natl Acad Sci USA 2002;99:821-826.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 821-826
    • Kline, D.D.1    Peng, Y.J.2    Manalo, D.J.3    Semenza, G.L.4    Prabhakar, N.R.5
  • 27
    • 33751117499 scopus 로고    scopus 로고
    • HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes
    • Shimoda LA, Fallon M, Pisarcik S, Wang J, Semenza GL. HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes. Am J Physiol Lung Cell Mol Physiol 2006;291:L941-L949.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291
    • Shimoda, L.A.1    Fallon, M.2    Pisarcik, S.3    Wang, J.4    Semenza, G.L.5
  • 28
    • 84877576147 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1α in pulmonary artery smooth muscle cells lowers vascular tone by decreasing myosin light chain phosphorylation
    • Kim YM, Barnes EA, Alvira CM, Ying L, Reddy S, Cornfield DN. Hypoxia-inducible factor-1α in pulmonary artery smooth muscle cells lowers vascular tone by decreasing myosin light chain phosphorylation. Circ Res 2013;112:1230-1233.
    • (2013) Circ Res , vol.112 , pp. 1230-1233
    • Kim, Y.M.1    Barnes, E.A.2    Alvira, C.M.3    Ying, L.4    Reddy, S.5    Cornfield, D.N.6
  • 29
    • 84893607772 scopus 로고    scopus 로고
    • HIF-1alpha in vascular smooth muscle regulated pulmonary hypertension in chronic hypoxia
    • Ball MK, Schumacker PT. HIF-1alpha in vascular smooth muscle regulated pulmonary hypertension in chronic hypoxia. Am J Respir Crit Care Med 2013;187:A5390.
    • (2013) Am J Respir Crit Care Med , vol.187
    • Ball, M.K.1    Schumacker, P.T.2
  • 33
    • 51649116447 scopus 로고    scopus 로고
    • Measurement of cardiac function using pressure-volume conductance catheter technique in mice and rats
    • Pacher P, Nagayama T, Mukhopadhyay P, Bátkai S, Kass DA. Measurement of cardiac function using pressure-volume conductance catheter technique in mice and rats. Nat Protoc 2008;3: 1422-1434.
    • (2008) Nat Protoc , vol.3 , pp. 1422-1434
    • Pacher, P.1    Nagayama, T.2    Mukhopadhyay, P.3    Bátkai, S.4    Kass, D.A.5
  • 35
    • 77952861606 scopus 로고    scopus 로고
    • Thrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension
    • Ochoa CD, Yu L, Al-Ansari E, Hales CA, Quinn DA. Thrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension. J Cardiothorac Surg 2010;5:32.
    • (2010) J Cardiothorac Surg , vol.5 , pp. 32
    • Ochoa, C.D.1    Yu, L.2    Al-Ansari, E.3    Hales, C.A.4    Quinn, D.A.5
  • 36
    • 77749304560 scopus 로고    scopus 로고
    • Toll-like receptor 4-deficient mice are resistant to chronic hypoxia-induced pulmonary hypertension
    • Young KC, Hussein SM, Dadiz R, deMello D, Devia C, Hehre D, Suguihara C. Toll-like receptor 4-deficient mice are resistant to chronic hypoxia-induced pulmonary hypertension. Exp Lung Res 2010;36:111-119.
    • (2010) Exp Lung Res , vol.36 , pp. 111-119
    • Young, K.C.1    Hussein, S.M.2    Dadiz, R.3    Demello, D.4    Devia, C.5    Hehre, D.6    Suguihara, C.7
  • 38
    • 0036933431 scopus 로고    scopus 로고
    • Hypoxic activation of adventitial fibroblasts: Role in vascular remodeling
    • Stenmark KR, Gerasimovskaya E, Nemenoff RA, Das M. Hypoxic activation of adventitial fibroblasts: role in vascular remodeling. Chest 2002;122(Suppl 6):326S-334S.
    • (2002) Chest , vol.122 , Issue.SUPPL. 6
    • Stenmark, K.R.1    Gerasimovskaya, E.2    Nemenoff, R.A.3    Das, M.4
  • 39
    • 33744735728 scopus 로고    scopus 로고
    • Pulmonary artery adventitial fibroblasts cooperate with vasa vasorum endothelial cells to regulate vasa vasorum neovascularization: A process mediated by hypoxia and endothelin-1
    • Davie NJ, Gerasimovskaya EV, Hofmeister SE, Richman AP, Jones PL, Reeves JT, Stenmark KR. Pulmonary artery adventitial fibroblasts cooperate with vasa vasorum endothelial cells to regulate vasa vasorum neovascularization: a process mediated by hypoxia and endothelin-1. Am J Pathol 2006;168:1793-1807.
    • (2006) Am J Pathol , vol.168 , pp. 1793-1807
    • Davie, N.J.1    Gerasimovskaya, E.V.2    Hofmeister, S.E.3    Richman, A.P.4    Jones, P.L.5    Reeves, J.T.6    Stenmark, K.R.7
  • 40
    • 0036776930 scopus 로고    scopus 로고
    • Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells: Role of hypoxia-inducible transcription factors
    • Rose F, Grimminger F, Appel J, Heller M, Pies V, Weissmann N, Fink L, Schmidt S, Krick S, Camenisch G, et al. Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells: role of hypoxia-inducible transcription factors. FASEB J 2002;16: 1660-1661.
    • (2002) FASEB J , vol.16 , pp. 1660-1661
    • Rose, F.1    Grimminger, F.2    Appel, J.3    Heller, M.4    Pies, V.5    Weissmann, N.6    Fink, L.7    Schmidt, S.8    Krick, S.9    Camenisch, G.10
  • 41
    • 19844374754 scopus 로고    scopus 로고
    • Bone marrow-derived cells contribute to pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension
    • Hayashida K, Fujita J, Miyake Y, Kawada H, Ando K, Ogawa S, Fukuda K. Bone marrow-derived cells contribute to pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension. Chest 2005;127:1793-1798.
    • (2005) Chest , vol.127 , pp. 1793-1798
    • Hayashida, K.1    Fujita, J.2    Miyake, Y.3    Kawada, H.4    Ando, K.5    Ogawa, S.6    Fukuda, K.7
  • 43
    • 22744455284 scopus 로고    scopus 로고
    • Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation
    • Hyvelin JM, Howell K, Nichol A, Costello CM, Preston RJ, McLoughlin P. Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation. Circ Res 2005;97:185-191.
    • (2005) Circ Res , vol.97 , pp. 185-191
    • Hyvelin, J.M.1    Howell, K.2    Nichol, A.3    Costello, C.M.4    Preston, R.J.5    McLoughlin, P.6
  • 47
    • 25144517059 scopus 로고    scopus 로고
    • Gene expression and phenotypic characterization of mouse heart after chronic constant or intermittent hypoxia
    • Fan C, Iacobas DA, Zhou D, Chen Q, Lai JK, Gavrialov O, Haddad GG. Gene expression and phenotypic characterization of mouse heart after chronic constant or intermittent hypoxia. Physiol Genomics 2005;22:292-307.
    • (2005) Physiol Genomics , vol.22 , pp. 292-307
    • Fan, C.1    Iacobas, D.A.2    Zhou, D.3    Chen, Q.4    Lai, J.K.5    Gavrialov, O.6    Haddad, G.G.7
  • 48
    • 45449115911 scopus 로고    scopus 로고
    • Integrated transcriptomic response to cardiac chronic hypoxia: Translation regulators and response to stress in cell survival
    • Iacobas DA, Fan C, Iacobas S, Haddad GG. Integrated transcriptomic response to cardiac chronic hypoxia: translation regulators and response to stress in cell survival. Funct Integr Genomics 2008;8: 265-275.
    • (2008) Funct Integr Genomics , vol.8 , pp. 265-275
    • Iacobas, D.A.1    Fan, C.2    Iacobas, S.3    Haddad, G.G.4
  • 51
    • 0035130107 scopus 로고    scopus 로고
    • Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell deathdependent pulmonary endothelial cell proliferation and severe pulmonary hypertension
    • Taraseviciene-Stewart L, Kasahara Y, Alger L, Hirth P, Mc Mahon G, Waltenberger J, Voelkel NF, Tuder RM. Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell deathdependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. FASEB J 2001;15:427-438.
    • (2001) FASEB J , vol.15 , pp. 427-438
    • Taraseviciene-Stewart, L.1    Kasahara, Y.2    Alger, L.3    Hirth, P.4    Mc Mahon, G.5    Waltenberger, J.6    Voelkel, N.F.7    Tuder, R.M.8
  • 53
    • 84857731222 scopus 로고    scopus 로고
    • The a "mAZE"ing world of lung-specific transgenic mice
    • Rawlins EL, Perl AK. The a "MAZE"ing world of lung-specific transgenic mice. Am J Respir Cell Mol Biol 2012;46:269-282.
    • (2012) Am J Respir Cell Mol Biol , vol.46 , pp. 269-282
    • Rawlins, E.L.1    Perl, A.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.