Nutrigenetics, metabolic syndrome risk and personalized nutrition

Current Vascular Pharmacology

Volumn 11, Issue 6, 2013, Pages 946-953

  Perez Martinez, Pablo ^a   Phillips, Catherine M ^b   Delgado Lista, Javier ^a   Garcia Rios, Antonio ^a   Lopez Miranda, Jose ^a   Perez Jimenez, Francisco ^a  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Diabetes mellitus; Diet; Gene diet interaction; Metabolic syndrome; Nutrigenomics; Polymorphism

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; APOLIPOPROTEIN A1; APOLIPOPROTEIN B; CCAAT ENHANCER BINDING PROTEIN ALPHA; COMPLEMENT COMPONENT C3; INTERLEUKIN 6; LEPTIN RECEPTOR; LONG CHAIN FATTY ACID COENZYME A LIGASE; LYMPHOTOXIN; TRANSCRIPTION FACTOR 7 LIKE 2; TUMOR NECROSIS FACTOR ALPHA;

ALLELE; DIET; DYSLIPIDEMIA; FOOD INTAKE; GENE DIET INTERACTION; GENE FREQUENCY; GENE LOCUS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETICS; HUMAN; INSULIN RESISTANCE; METABOLIC SYNDROME X; NUTRIGENETICS; NUTRITION; OBESITY; REVIEW; RISK; RISK FACTOR;

ANIMALS; BLOOD GLUCOSE; DIET; FATTY ACIDS; HUMANS; INDIVIDUALIZED MEDICINE; METABOLIC SYNDROME X; NUTRIGENOMICS; NUTRITIONAL STATUS; RISK FACTORS;

EID: 84893513135     PISSN: 15701611     EISSN: 18756212     Source Type: Journal    
DOI: 10.2174/157016111106140128120911     Document Type: Review

References (65)

1. Delgado-Lista J, Garcia-Rios A, Perez-Martinez P, et al. Gene variations of nitric oxide synthase regulate the effects of a saturated fat rich meal on endothelial function. Clin Nutr 2011; 30(2): 234-8.
2. Ordovas JM, Mooser V. Nutrigenomics and nutrigenetics. Curr Opin Lipidol 2004; 15(2): 101-8.
3. Perez-Martinez P, Lopez-Miranda J, Ordovas JM, Perez-Jimenez F. [Nutrition in the age of genomics: towards a personalized diet]. Med Clin (Barc) 2008; 130(3): 103-8.
4. Garcia-Rios A, Perez-Martinez P, Delgado-Lista J, Lopez-Miranda J, Perez-Jimenez F. Nutrigenetics of the lipoprotein metabolism. Mol Nutr Food Res 2012; 56(1): 171-83.
5. Perez-Martinez P, Lopez-Miranda J, Perez-Jimenez F, Ordovas JM. Influence of genetic factors in the modulation of postprandial lipemia. Atheroscler Suppl 2008; 9(2): 49-55.
6. Perez-Martinez P, Delgado-Lista J, Perez-Jimenez F, Lopez-Miranda J. Update on genetics of postprandial lipemia. Atheroscler Suppl 2010; 11(1): 39-43.
7. Mihas C, Kolovou GD, Mikhailidis DP, et al. Diagnostic value of postprandial triglyceride testing in healthy subjects: a metaanalysis. Curr Vasc Pharmacol 2011; 9(3): 271-80.
8. Tierney AC, McMonagle J, Shaw DI, et al. Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome-LIPGENE: a European randomized dietary intervention study. Int J Obes 2011; 35(6): 800-9.
9. Paniagua JA, Perez-Martinez P, Gjelstad IM, et al. A low-fat highcarbohydrate diet supplemented with long-chain n-3 PUFA reduces the risk of the metabolic syndrome. Atherosclerosis 2011; 218(2): 443-50.
10. Meneses ME, Camargo A, Perez-Martinez P, et al. Postprandial inflammatory response in adipose tissue of patients with metabolic syndrome after the intake of different dietary models. Mol Nutr Food Res 2011; 55(12): 1759-70.
11. Petersson H, Riserus U, McMonagle J, et al. Effects of dietary fat modification on oxidative stress and inflammatory markers in the LIPGENE study. Br J Nutr 2010; 104(9): 1357-62.
12. Perez-Martinez P, Moreno-Conde M, Cruz-Teno C, et al. Dietary fat differentially influences regulatory endothelial function during the postprandial state in patients with metabolic syndrome: from the LIPGENE study. Atherosclerosis 2010; 209(2): 533-8.
13. Perez-Martinez P, Garcia-Quintana JM, Yubero-Serrano EM, et al. Postprandial oxidative stress is modified by dietary fat: evidence from a human intervention study. Clin Sci (Lond) 2010; 119(6): 251-61.
14. Gulseth HL, Gjelstad IM, Tierney AC, et al. Dietary fat modifications and blood pressure in subjects with the metabolic syndrome in the LIPGENE dietary intervention study. Br J Nutr 2010; 104(2): 160-3.
15. Phillips C, Lopez-Miranda J, Perez-Jimenez F, McManus R, Roche HM. Genetic and nutrient determinants of the metabolic syndrome. Curr Opin Cardiol 2006; 21(3): 185-93.
16. Perez-Martinez P, Delgado-Lista J, Garcia-Rios A, et al. Calpain-10 interacts with plasma saturated fatty acid concentrations to influence insulin resistance in individuals with the metabolic syndrome. Am J Clin Nutr 2011; 93(5): 1136-41.
17. Marin C, Ramirez R, Delgado-Lista J, et al. Mediterranean diet reduces endothelial damage and improves the regenerative capacity of endothelium. Am J Clin Nutr 2011; 93(2): 267-74.
18. Ferguson JF, Phillips CM, Tierney AC, et al. Gene-nutrient interactions in the metabolic syndrome: single nucleotide polymorphisms in ADIPOQ and ADIPOR1 interact with plasma saturated fatty acids to modulate insulin resistance. Am J Clin Nutr 2010; 91(3): 794-801.
19. Perez-Martinez P, Lopez-Miranda J, Cruz-Teno C, et al. Adiponectin gene variants are associated with insulin sensitivity in response to dietary fat consumption in Caucasian men. J Nutr 2008; 138(9): 1609-14.
20. Delgado-Lista J, Perez-Martinez P, Garcia-Rios A, et al. Pleiotropic effects of TCF7L2 gene variants and its modulation in the metabolic syndrome: from the LIPGENE study. Atherosclerosis 2011; 214(1): 110-6.
21. Perez-Martinez P, Perez-Jimenez F, Bellido C, et al. A polymorphism exon 1 variant at the locus of the scavenger receptor class B type I (SCARB1) gene is associated with differences in insulin sensitivity in healthy people during the consumption of an olive oil-rich diet. J Clin Endocrinol Metab 2005; 90(4): 2297-300.
22. Perez-Martinez P, Garcia-Rios A, Delgado-Lista J, Perez-Jimenez F, Lopez-Miranda J. Metabolic syndrome: Evidences for a personalized nutrition. Mol Nutr Food Res 2012; 56(1): 67-76.
23. Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes care 2004; 27(5): 1047-53.
24. Esparza-Romero J, Valencia ME, Martinez ME, Ravussin E, Schulz LO, Bennett PH. Differences in insulin resistance in Mexican and U. S. Pima Indians with normal glucose tolerance. J Clin Endocrinol Metab 2010; 95(11): E358-62.
25. Schulz LO, Bennett PH, Ravussin E, et al. Effects of traditional and western environments on prevalence of type 2 diabetes in Pima Indians in Mexico and the U. S. Diabetes care 2006; 29(8): 1866-71.
26. Kabagambe EK, Tsai MY, Hopkins PN, et al. Erythrocyte fatty acid composition and the metabolic syndrome: a National Heart, Lung, and Blood Institute GOLDN study. Clin Chem 2008; 54(1): 154-62.
27. Phillips C, Lopez-Miranda J, Perez-Jimenez F, McManus R, Roche HM. Genetic and nutrient determinants of the metabolic syndrome. Curr Opin Cardiol 2006; 21(3): 185-93.
28. Roche HM, Phillips C, Gibney MJ. The metabolic syndrome: The crossroads of diet and genetics. Proc Nutr Soc 2005; 64(3): 371-7.
29. Vessby B. Dietary fat, fatty acid composition in plasma and the metabolic syndrome. Curr Opin Lipidol 2003; 14(1): 15-9.
30. Warensjo E, Sundstrom J, Lind L, Vessby B. Factor analysis of fatty acids in serum lipids as a measure of dietary fat quality in relation to the metabolic syndrome in men. Am J Clin Nutr 2006; 84(2): 442-8.
31. Phillips CM, Tierney AC, Roche HM. Gene-nutrient interactions in the metabolic syndrome. J Nutrigenet Nutrigenomics 2008; 1(3): 136-51.
32. Phillips CM, Goumidi L, Bertrais S, et al. ACC2 gene polymorphisms, metabolic syndrome, and gene-nutrient interactions with dietary fat. J Lipid Res 2010; 51(12): 3500-7.
33. Delgado-Lista J, Perez-Jimenez F, Ruano J, et al. Effects of variations in the APOA1/C3/A4/A5 gene cluster on different parameters of postprandial lipid metabolism in healthy young men. J Lipid Res 2010; 51(1): 63-73.
34. Phillips CM, Goumidi L, Bertrais S, et al. Gene-nutrient interactions and gender may modulate the association between ApoA1 and ApoB gene polymorphisms and metabolic syndrome risk. Atherosclerosis 2011; 214(2): 408-14.
35. Onat A, Hergenc G, Can G, Kaya Z, Yuksel H. Serum complement C3: a determinant of cardiometabolic risk, additive to the metabolic syndrome, in middle-aged population. Metabolism: clinical and experimental. 2010; 59(5): 628-34.
36. Phillips CM, Goumidi L, Bertrais S, et al. Complement component 3 polymorphisms interact with polyunsaturated fatty acids to modulate risk of metabolic syndrome. Am J Clin Nutr 2009; 90(6): 1665-73.
37. Phillips CM, Goumidi L, Bertrais S, et al. Leptin receptor polymorphisms interact with polyunsaturated fatty acids to augment risk of insulin resistance and metabolic syndrome in adults. J Nutr 2010; 140(2): 238-44.
38. Coleman RA, Lewin TM, Muoio DM. Physiological and nutritional regulation of enzymes of triacylglycerol synthesis. Ann Rev Nutr 2000; 20: 77-103.
39. McGarry JD. Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes 2002; 51(1): 7-18.
40. Shimabukuro M, Zhou YT, Levi M, Unger RH. Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes. Proc Natl Acad Sci USA 1998; 95(5): 2498-502.
41. Phillips CM, Goumidi L, Bertrais S, et al. Gene-nutrient interactions with dietary fat modulate the association between genetic variation of the ACSL1 gene and metabolic syndrome. J Lipid Res 2010; 51(7): 1793-800.
42. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002; 106(25): 3143-421.
43. Carter KW, Hung J, Powell BL, et al. Association of Interleukin-1 gene polymorphisms with central obesity and metabolic syndrome in a coronary heart disease population. Hum Genet 2008; 124(3): 199-206.
44. Hu FB, Meigs JB, Li TY, Rifai N, Manson JE. Inflammatory markers and risk of developing type 2 diabetes in women. Diabetes 2004; 53(3): 693-700.
45. Spranger J, Kroke A, Mohlig M, et al. Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Diabetes 2003; 52(3): 812-7.
46. Dalziel B, Gosby AK, Richman RM, Bryson JM, Caterson ID. Association of the TNF-alpha-308 G/A promoter polymorphism with insulin resistance in obesity. Obes Res. 2002; 10(5): 401-7.
47. Hamid YH, Rose CS, Urhammer SA, et al. Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes. Diabetologia 2005; 48(2): 251-60.
48. Huth C, Heid IM, Vollmert C, et al. IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies. Diabetes 2006; 55(10): 2915-21.
49. Shen J, Arnett DK, Perez-Martinez P, et al. The effect of IL6-174C/G polymorphism on postprandial triglyceride metabolism in the GOLDN studyboxs. J Lipid Res 2008; 49(8): 1839-45.
50. Sookoian S, Garcia SI, Gianotti TF, Dieuzeide G, Gonzalez CD, Pirola CJ. The G-308A promoter variant of the tumor necrosis factor-alpha gene is associated with hypertension in adolescents harboring the metabolic syndrome. Am J Hypertens 2005; 18(10): 1271-5.
51. Delgado-Lista J, Garcia-Rios A, Perez-Martinez P, et al. Interleukin 1B variant-1473G/C (rs1143623) influences triglyceride and interleukin 6 metabolism. J Clin Endocrinol Metab 2011; 96(5): E816-20.
52. Meirhaeghe A, Cottel D, Amouyel P, Dallongeville J. Lack of association between certain candidate gene polymorphisms and the metabolic syndrome. Mol Genet Metab 2005; 86(1-2): 293-9.
53. Qi L, Zhang C, van Dam RM, Hu FB. Interleukin-6 genetic variability and adiposity: associations in two prospective cohorts and systematic review in 26, 944 individuals. J Clin Endocrinol Metab 2007; 92(9): 3618-25.
54. Phillips CM, Goumidi L, Bertrais S, et al. Additive effect of polymorphisms in the IL-6, LTA, and TNF-{alpha} genes and plasma fatty acid level modulate risk for the metabolic syndrome and its components. J Clin Endocrinol Metab 2010; 95(3): 1386-94.
55. Florez JC, Jablonski KA, Bayley N, et al. TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. New Engl J Med 2006; 355(3): 241-50.
56. Marzi C, Huth C, Kolz M, et al. Variants of the transcription factor 7-like 2 gene (TCF7L2) are strongly associated with type 2 diabetes but not with the metabolic syndrome in the MONICA/KORA surveys. Horm Metab Res 2007; 39(1): 46-52.
57. Phillips CM, Goumidi L, Bertrais S, et al. Dietary saturated fat, gender and genetic variation at the TCF7L2 locus predict the development of metabolic syndrome. J Nutr Biochem 2012; 23(3): 239-44.
58. Bennett CE, Nsengimana J, Bostock JA, et al. CCAAT/enhancer binding protein alpha, beta and delta gene variants: associations with obesity related phenotypes in the Leeds Family Study. Diab Vasc Dis Res 2010; 7(3): 195-203.
59. El-Jack AK, Hamm JK, Pilch PF, Farmer SR. Reconstitution of insulin-sensitive glucose transport in fibroblasts requires expression of both PPARgamma and C/EBPalpha. J Biol Chem 1999; 274(12): 7946-51.
60. Olofsson LE, Orho-Melander M, William-Olsson L, et al. CCAAT/enhancer binding protein alpha (C/EBPalpha) in adipose tissue regulates genes in lipid and glucose metabolism and a genetic variation in C/EBPalpha is associated with serum levels of triglycerides. J Clin Endocrinol Metab 2008; 93(12): 4880-6.
61. Tan EH, Hooi SC, Laban M, et al. CCAAT/enhancer binding protein alpha knock-in mice exhibit early liver glycogen storage and reduced susceptibility to hepatocellular carcinoma. Cancer Res 2005; 65(22): 10330-7.
62. Delgado-Lista J, Perez-Martinez P, Garcia-Rios A, et al. A gene variation (rs12691) in the CCAT/enhancer binding protein alpha modulates glucose metabolism in metabolic syndrome. Nutr Metab Cardiovasc Dis 2011 Jan 21: (EPUB ahead of print). doi: 10. 1016/j. numecd. 2011. 09. 008.
63. Kim K, Yang YJ, Kim MK. Interactions of single nucleotide polymorphisms with dietary calcium intake on the risk of metabolic syndrome. Ame J Clin Nutr 2012; 95(1): 231-40.
64. Robitaille J, Gaudet D, Perusse L, Vohl MC. Features of the metabolic syndrome are modulated by an interaction between the peroxisome proliferator-activated receptor-delta-87T>C polymorphism and dietary fat in French-Canadians. Int J Obes (Lond) 2007; 31(3): 411-7.
65. Perez-Martinez P, Gomez P, Paz E, et al. Interaction between smoking and the Sstl polymorphism of the apo C-III gene determines plasma lipid response to diet. Nutr Metab Cardiovasc Dis 2001; 11(4): 237-43.