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Volumn 8, Issue 1, 2014, Pages 332-339

Three-dimensional hydrodynamic focusing method for polyplex synthesis

Author keywords

3D hydrodynamic focusing; gene delivery; polyplex; transfection

Indexed keywords

ACOUSTIC PERTURBATIONS; BATCH-TO-BATCH VARIATIONS; GENE DELIVERY; HYDRODYNAMIC FOCUSING; POLYMERIC GENE CARRIERS; POLYPLEXES; TRANSFECTION; TRANSFECTION EFFICIENCY;

EID: 84893511366     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn404193e     Document Type: Article
Times cited : (47)

References (67)
  • 1
    • 0038574350 scopus 로고    scopus 로고
    • Non-Viral Gene Therapy: Polycation-Mediated DNA Delivery
    • Thomas, M.; Klibanov, A. M. Non-Viral Gene Therapy: Polycation-Mediated DNA Delivery Appl. Microbiol. Biotechnol. 2003, 62, 27-34
    • (2003) Appl. Microbiol. Biotechnol. , vol.62 , pp. 27-34
    • Thomas, M.1    Klibanov, A.M.2
  • 2
    • 77955879616 scopus 로고    scopus 로고
    • Polycation Cytotoxicity: A Delicate Matter for Nucleic Acid Therapy-Focus on Polyethylenimine
    • Parhamifar, L.; Larsen, A. K.; Hunter, A. C.; Andresen, T. L.; Moghimi, S. M. Polycation Cytotoxicity: A Delicate Matter for Nucleic Acid Therapy-Focus on Polyethylenimine Soft Matter 2010, 6, 4001-4009
    • (2010) Soft Matter , vol.6 , pp. 4001-4009
    • Parhamifar, L.1    Larsen, A.K.2    Hunter, A.C.3    Andresen, T.L.4    Moghimi, S.M.5
  • 3
    • 77951916908 scopus 로고    scopus 로고
    • Balancing Protection and Release of DNA: Tools to Address a Bottleneck of Non-Viral Gene Delivery
    • Grigsby, C. L.; Leong, K. W. Balancing Protection and Release of DNA: Tools to Address a Bottleneck of Non-Viral Gene Delivery J. R. Soc. Interface 2010, 7, S67-S82
    • (2010) J. R. Soc. Interface , vol.7
    • Grigsby, C.L.1    Leong, K.W.2
  • 4
    • 77954283440 scopus 로고    scopus 로고
    • Dual-Sensitive Micellar Nanoparticles Regulate DNA Unpacking and Enhance Gene-Delivery Efficiency
    • Jiang, X. A.; Zheng, Y. R.; Chen, H. H.; Leong, K. W.; Wang, T. H.; Mao, H. Q. Dual-Sensitive Micellar Nanoparticles Regulate DNA Unpacking and Enhance Gene-Delivery Efficiency Adv. Mater. 2010, 22, 2556-2560
    • (2010) Adv. Mater. , vol.22 , pp. 2556-2560
    • Jiang, X.A.1    Zheng, Y.R.2    Chen, H.H.3    Leong, K.W.4    Wang, T.H.5    Mao, H.Q.6
  • 5
    • 84889588946 scopus 로고    scopus 로고
    • Microfluidic Preparation of Polymer-Nucleic Acid Nanocomplexes Improves Nonviral Gene Transfer
    • Grigsby, C. L.; Ho, Y.-P.; Lin, C.; Engbersen, J. F. J.; Leong, K. W. Microfluidic Preparation of Polymer-Nucleic Acid Nanocomplexes Improves Nonviral Gene Transfer Sci. Rep. 2013, 3, 3155
    • (2013) Sci. Rep. , vol.3 , pp. 3155
    • Grigsby, C.L.1    Ho, Y.-P.2    Lin, C.3    Engbersen, J.F.J.4    Leong, K.W.5
  • 6
    • 19544362720 scopus 로고    scopus 로고
    • Mechanistic Studies on Aggregation of Polyethylenimine-DNA Complexes and Its Prevention
    • Sharma, V. K.; Thomas, M.; Klibanov, A. M. Mechanistic Studies on Aggregation of Polyethylenimine-DNA Complexes and Its Prevention Biotechnol. Bioeng. 2005, 90, 614-620
    • (2005) Biotechnol. Bioeng. , vol.90 , pp. 614-620
    • Sharma, V.K.1    Thomas, M.2    Klibanov, A.M.3
  • 7
    • 0033050727 scopus 로고    scopus 로고
    • Physicochemical Characterization and Purification of Cationic Lipoplexes
    • Xu, Y. H.; Hui, S. W.; Frederik, P.; Szoka, F. C. Physicochemical Characterization and Purification of Cationic Lipoplexes Biophys. J. 1999, 77, 341-353
    • (1999) Biophys. J. , vol.77 , pp. 341-353
    • Xu, Y.H.1    Hui, S.W.2    Frederik, P.3    Szoka, F.C.4
  • 9
    • 79955907483 scopus 로고    scopus 로고
    • Tuning Physical Properties of Nanocomplexes through Microfluidics- Assisted Confinement
    • Ho, Y. P.; Grigsby, C. L.; Zhao, F.; Leong, K. W. Tuning Physical Properties of Nanocomplexes through Microfluidics-Assisted Confinement Nano Lett. 2011, 11, 2178-2182
    • (2011) Nano Lett. , vol.11 , pp. 2178-2182
    • Ho, Y.P.1    Grigsby, C.L.2    Zhao, F.3    Leong, K.W.4
  • 10
    • 0030462391 scopus 로고    scopus 로고
    • Optimized Galenics Improve in Vitro Gene Transfer with Cationic Molecules up to 1000-fold
    • Boussif, O.; Zanta, M. A.; Behr, J. P. Optimized Galenics Improve in Vitro Gene Transfer with Cationic Molecules up to 1000-fold Gene Ther. 1996, 3, 1074-1080
    • (1996) Gene Ther. , vol.3 , pp. 1074-1080
    • Boussif, O.1    Zanta, M.A.2    Behr, J.P.3
  • 11
    • 33747117373 scopus 로고    scopus 로고
    • The Origins and the Future of Microfluidics
    • Whitesides, G. M. The Origins and the Future of Microfluidics Nature 2006, 442, 368-373
    • (2006) Nature , vol.442 , pp. 368-373
    • Whitesides, G.M.1
  • 12
    • 84858991169 scopus 로고    scopus 로고
    • Microfluidic Diagnostics for the Developing World
    • Mao, X.; Huang, T. J. Microfluidic Diagnostics for the Developing World Lab Chip 2012, 12, 1412-1416
    • (2012) Lab Chip , vol.12 , pp. 1412-1416
    • Mao, X.1    Huang, T.J.2
  • 16
    • 84871033897 scopus 로고    scopus 로고
    • Microfluidic Technologies for Accelerating the Clinical Translation of Nanoparticles
    • Valencia, P. M.; Farokhzad, O. C.; Karnik, R.; Langer, R. Microfluidic Technologies for Accelerating the Clinical Translation of Nanoparticles Nat. Nanotechnol. 2012, 7, 623-629
    • (2012) Nat. Nanotechnol. , vol.7 , pp. 623-629
    • Valencia, P.M.1    Farokhzad, O.C.2    Karnik, R.3    Langer, R.4
  • 17
    • 75749104689 scopus 로고    scopus 로고
    • Micronozzle Array Enhanced Sandwich Electroporation of Embryonic Stem Cells
    • Fei, Z. Z.; Hu, X.; Choi, H. W.; Wang, S. N.; Farson, D.; Lee, L. J. Micronozzle Array Enhanced Sandwich Electroporation of Embryonic Stem Cells Anal. Chem. 2010, 82, 353-358
    • (2010) Anal. Chem. , vol.82 , pp. 353-358
    • Fei, Z.Z.1    Hu, X.2    Choi, H.W.3    Wang, S.N.4    Farson, D.5    Lee, L.J.6
  • 18
    • 84893494637 scopus 로고    scopus 로고
    • Manufacturing DNA Nanowires with Air Blowing Assembly on Micropatterned Surface
    • Rajagopalan, K. K.; Chen, J.; Lu, B.; Wang, S. Manufacturing DNA Nanowires with Air Blowing Assembly on Micropatterned Surface Nano LIFE 2013, 1, 1350001-9
    • (2013) Nano LIFE , vol.1 , pp. 1350001-1350009
    • Rajagopalan, K.K.1    Chen, J.2    Lu, B.3    Wang, S.4
  • 22
    • 78049325879 scopus 로고    scopus 로고
    • A Rapid Pathway toward a Superb Gene Delivery System: Programming Structural and Functional Diversity into a Supramolecular Nanoparticle Library
    • Wang, H.; Liu, K.; Chen, K.-J.; Lu, Y.; Wang, S.; Lin, W.-Y.; Guo, F.; Kamei, K.-I.; Chen, Y.-C.; Ohashi, M. A Rapid Pathway toward a Superb Gene Delivery System: Programming Structural and Functional Diversity into a Supramolecular Nanoparticle Library ACS Nano 2010, 4, 6235-6243
    • (2010) ACS Nano , vol.4 , pp. 6235-6243
    • Wang, H.1    Liu, K.2    Chen, K.-J.3    Lu, Y.4    Wang, S.5    Lin, W.-Y.6    Guo, F.7    Kamei, K.-I.8    Chen, Y.-C.9    Ohashi, M.10
  • 23
    • 77958609026 scopus 로고    scopus 로고
    • A Digital Microfluidic Droplet Generator Produces Self-Assembled Supramolecular Nanoparticles for Targeted Cell Imaging
    • Liu, K.; Wang, H.; Chen, K.-J.; Guo, F.; Lin, W.-Y.; Chen, Y.-C.; Phung, D. L.; Tseng, H.-R.; Shen, C. K.-F. A Digital Microfluidic Droplet Generator Produces Self-Assembled Supramolecular Nanoparticles for Targeted Cell Imaging Nanotechnology 2010, 21, 445603
    • (2010) Nanotechnology , vol.21 , pp. 445603
    • Liu, K.1    Wang, H.2    Chen, K.-J.3    Guo, F.4    Lin, W.-Y.5    Chen, Y.-C.6    Phung, D.L.7    Tseng, H.-R.8    Shen, C.K.-F.9
  • 25
    • 79960349970 scopus 로고    scopus 로고
    • On-Demand Preparation of Quantum Dot-Encoded Microparticles Using a Droplet Microfluidic System
    • Ji, X.-H.; Cheng, W.; Guo, F.; Liu, W.; Guo, S.-S.; He, Z.-K.; Zhao, X.-Z. On-Demand Preparation of Quantum Dot-Encoded Microparticles Using a Droplet Microfluidic System Lab Chip 2011, 11, 2561-2568
    • (2011) Lab Chip , vol.11 , pp. 2561-2568
    • Ji, X.-H.1    Cheng, W.2    Guo, F.3    Liu, W.4    Guo, S.-S.5    He, Z.-K.6    Zhao, X.-Z.7
  • 26
    • 80052065542 scopus 로고    scopus 로고
    • Integrated Parallel Microfluidic Device for Simultaneous Preparation of Multiplex Optical-Encoded Microbeads with Distinct Quantum Dot Barcodes
    • Ji, X.-H.; Zhang, N.-G.; Cheng, W.; Guo, F.; Liu, W.; Guo, S.-S.; He, Z.-K.; Zhao, X.-Z. Integrated Parallel Microfluidic Device for Simultaneous Preparation of Multiplex Optical-Encoded Microbeads with Distinct Quantum Dot Barcodes J. Mater. Chem. 2011, 21, 13380-13387
    • (2011) J. Mater. Chem. , vol.21 , pp. 13380-13387
    • Ji, X.-H.1    Zhang, N.-G.2    Cheng, W.3    Guo, F.4    Liu, W.5    Guo, S.-S.6    He, Z.-K.7    Zhao, X.-Z.8
  • 27
    • 84862180515 scopus 로고    scopus 로고
    • Microfluidic Synthesis of Multifunctional Janus Particles for Biomedical Applications
    • Yang, S.; Guo, F.; Kiraly, B.; Mao, X.; Lu, M.; Leong, K. W.; Huang, T. J. Microfluidic Synthesis of Multifunctional Janus Particles for Biomedical Applications Lab Chip 2012, 12, 2097-2102
    • (2012) Lab Chip , vol.12 , pp. 2097-2102
    • Yang, S.1    Guo, F.2    Kiraly, B.3    Mao, X.4    Lu, M.5    Leong, K.W.6    Huang, T.J.7
  • 28
    • 78650695686 scopus 로고    scopus 로고
    • The Establishment of an Up-Scaled Micro-Mixer Method Allows the Standardized and Reproducible Preparation of Well-Defined Plasmid/LPEI Polyplexes
    • Kasper, J. C.; Schaffert, D.; Ogris, M.; Wagner, E.; Friess, W. The Establishment of an Up-Scaled Micro-Mixer Method Allows the Standardized and Reproducible Preparation of Well-Defined Plasmid/LPEI Polyplexes Eur. J. Pharm. Biopharm. 2011, 77, 182-185
    • (2011) Eur. J. Pharm. Biopharm. , vol.77 , pp. 182-185
    • Kasper, J.C.1    Schaffert, D.2    Ogris, M.3    Wagner, E.4    Friess, W.5
  • 29
    • 84862842189 scopus 로고    scopus 로고
    • Optimized Preparation of pDNA/poly(ethylene imine) Polyplexes Using a Microfluidic System
    • Debus, H.; Beck-Broichsitter, M.; Kissel, T. Optimized Preparation of pDNA/poly(ethylene imine) Polyplexes Using a Microfluidic System Lab Chip 2012, 12, 2498-2506
    • (2012) Lab Chip , vol.12 , pp. 2498-2506
    • Debus, H.1    Beck-Broichsitter, M.2    Kissel, T.3
  • 30
    • 84864690677 scopus 로고    scopus 로고
    • Microfluidic Platform for on-Demand Generation of Spatially Indexed Combinatorial Droplets
    • Zec, H.; Rane, T. D.; Wang, T. H. Microfluidic Platform for on-Demand Generation of Spatially Indexed Combinatorial Droplets Lab Chip 2012, 12, 3055-3062
    • (2012) Lab Chip , vol.12 , pp. 3055-3062
    • Zec, H.1    Rane, T.D.2    Wang, T.H.3
  • 31
    • 50149118418 scopus 로고    scopus 로고
    • Quantitative Kinetic Analysis of DNA Nanocomplex Self-Assembly with Quantum Dots FRET in a Microfluidic Device
    • Ho, Y. P.; Chen, H. H.; Puleo, C. M.; Yeh, H. C.; Leong, K. W.; Wang, T. H. Quantitative Kinetic Analysis of DNA Nanocomplex Self-Assembly with Quantum Dots FRET in a Microfluidic Device Proc. IEEE Micro. Electro. 2008, 30-33
    • (2008) Proc. IEEE Micro. Electro. , pp. 30-33
    • Ho, Y.P.1    Chen, H.H.2    Puleo, C.M.3    Yeh, H.C.4    Leong, K.W.5    Wang, T.H.6
  • 32
    • 71549133732 scopus 로고    scopus 로고
    • Multiscale Materials from Microcontinuous-Flow Syntheis: ZnO and Au Nanoparticle-Filled Uniform and Homogeneous Polymer Microbeads
    • Chang, Z.; Serra, C. A.; Bouquey, M.; Kraus, I.; Li, S.; Köhler, J. M. Multiscale Materials from Microcontinuous-Flow Syntheis: ZnO and Au Nanoparticle-Filled Uniform and Homogeneous Polymer Microbeads Nanotechnology 2010, 21, 015605
    • (2010) Nanotechnology , vol.21 , pp. 015605
    • Chang, Z.1    Serra, C.A.2    Bouquey, M.3    Kraus, I.4    Li, S.5    Köhler, J.M.6
  • 33
    • 0000035628 scopus 로고    scopus 로고
    • Hydrodynamic Focusing on a Silicon Chip: Mixing Nanoliters in Microseconds
    • Knight, J. B.; Vishwanath, A.; Brody, J. P.; Austin, R. H. Hydrodynamic Focusing on a Silicon Chip: Mixing Nanoliters in Microseconds Phys. Rev. Lett. 1998, 80, 3863-3866
    • (1998) Phys. Rev. Lett. , vol.80 , pp. 3863-3866
    • Knight, J.B.1    Vishwanath, A.2    Brody, J.P.3    Austin, R.H.4
  • 34
    • 34547663221 scopus 로고    scopus 로고
    • Three-Dimensional Hydrodynamic Focusing in Two-Layer Polydimethylsiloxane (PDMS) Microchannels
    • Chang, C. C.; Huang, Z. X.; Yang, R. J. Three-Dimensional Hydrodynamic Focusing in Two-Layer Polydimethylsiloxane (PDMS) Microchannels J. Micromech. Microeng. 2007, 17, 1479-1486
    • (2007) J. Micromech. Microeng. , vol.17 , pp. 1479-1486
    • Chang, C.C.1    Huang, Z.X.2    Yang, R.J.3
  • 35
    • 80755125404 scopus 로고    scopus 로고
    • Microfluidic Approaches for Gene Delivery and Gene Therapy
    • Kim, J.; Hwang, I.; Britain, D.; Chung, T. D.; Sun, Y.; Kim, D. H. Microfluidic Approaches for Gene Delivery and Gene Therapy Lab Chip 2011, 11, 3941-3948
    • (2011) Lab Chip , vol.11 , pp. 3941-3948
    • Kim, J.1    Hwang, I.2    Britain, D.3    Chung, T.D.4    Sun, Y.5    Kim, D.H.6
  • 36
  • 37
    • 0000259359 scopus 로고    scopus 로고
    • Experimental and Theoretical Scaling Laws for Transverse Diffusive Broadening in Two-Phase Laminar Flows in Microchannels
    • Ismagilov, R. F.; Stroock, A. D.; Kenis, P. J. A.; Whitesides, G.; Stone, H. A. Experimental and Theoretical Scaling Laws for Transverse Diffusive Broadening in Two-Phase Laminar Flows in Microchannels Appl. Phys. Lett. 2000, 76, 2376-2378
    • (2000) Appl. Phys. Lett. , vol.76 , pp. 2376-2378
    • Ismagilov, R.F.1    Stroock, A.D.2    Kenis, P.J.A.3    Whitesides, G.4    Stone, H.A.5
  • 39
    • 4344660693 scopus 로고    scopus 로고
    • Three-Dimensional Hydrocynamic Focusing in Polydimethylsiloxane (PDMS) Microchannels
    • Sundararajan, N.; Pio, M. S.; Lee, L. P.; Berlin, A. A. Three-Dimensional Hydrocynamic Focusing in Polydimethylsiloxane (PDMS) Microchannels J. Microelectromech. Syst. 2004, 13, 559-567
    • (2004) J. Microelectromech. Syst. , vol.13 , pp. 559-567
    • Sundararajan, N.1    Pio, M.S.2    Lee, L.P.3    Berlin, A.A.4
  • 41
    • 33750582154 scopus 로고    scopus 로고
    • A Monolithically Three-Dimensional Flow-Focusing Device for Formation of Single/Double Emulsions in Closed/Open Microfluidic Systems
    • Huang, S.; Tan, W.; Tseng, F.; Takeuchi, S. A Monolithically Three-Dimensional Flow-Focusing Device for Formation of Single/Double Emulsions in Closed/Open Microfluidic Systems J. Micromech. Microeng. 2006, 16, 2336
    • (2006) J. Micromech. Microeng. , vol.16 , pp. 2336
    • Huang, S.1    Tan, W.2    Tseng, F.3    Takeuchi, S.4
  • 42
    • 42949107116 scopus 로고    scopus 로고
    • Three-Dimensional Hydrodynamic Focusing in a Microfluidic Coulter Counter
    • Scott, R.; Sethu, P.; Harnett, C. K. Three-Dimensional Hydrodynamic Focusing in a Microfluidic Coulter Counter Rev. Sci. Instrum. 2008, 79, 046104
    • (2008) Rev. Sci. Instrum. , vol.79 , pp. 046104
    • Scott, R.1    Sethu, P.2    Harnett, C.K.3
  • 43
    • 79953058675 scopus 로고    scopus 로고
    • Synthesis of Size-Tunable Polymeric Nanoparticles Enabled by 3D Hydrodynamic Flow Focusing in Single-Layer Microchannels
    • Rhee, M.; Valencia, P. M.; Rodriguez, M. I.; Langer, R.; Farokhzad, O. C.; Karnik, R. Synthesis of Size-Tunable Polymeric Nanoparticles Enabled by 3D Hydrodynamic Flow Focusing in Single-Layer Microchannels Adv. Mater. 2011, H79-H83
    • (2011) Adv. Mater.
    • Rhee, M.1    Valencia, P.M.2    Rodriguez, M.I.3    Langer, R.4    Farokhzad, O.C.5    Karnik, R.6
  • 44
    • 66149096113 scopus 로고    scopus 로고
    • Single-Layer Planar on-Chip Flow Cytometer Using Microfluidic Drifting Based Three-Dimensional (3D) Hydrodynamic Focusing
    • Mao, X. L.; Lin, S. C. S.; Dong, C.; Huang, T. J. Single-Layer Planar on-Chip Flow Cytometer Using Microfluidic Drifting Based Three-Dimensional (3D) Hydrodynamic Focusing Lab Chip 2009, 9, 1583-1589
    • (2009) Lab Chip , vol.9 , pp. 1583-1589
    • Mao, X.L.1    Lin, S.C.S.2    Dong, C.3    Huang, T.J.4
  • 45
    • 34748871932 scopus 로고    scopus 로고
    • "microfluidic Drifting'' - Implementing Three-Dimensional Hydrodynamic Focusing with a Single-Layer Planar Microfluidic Device
    • Mao, X. L.; Waldeisen, J. R.; Huang, T. J. "Microfluidic Drifting''-Implementing Three-Dimensional Hydrodynamic Focusing with a Single-Layer Planar Microfluidic Device Lab Chip 2007, 7, 1260-1262
    • (2007) Lab Chip , vol.7 , pp. 1260-1262
    • Mao, X.L.1    Waldeisen, J.R.2    Huang, T.J.3
  • 46
    • 84863191336 scopus 로고    scopus 로고
    • An Integrated, Multiparametric Flow Cytometry Chip Using "microfluidic Drifting" Based Three-Dimensional Hydrodynamic Focusing
    • Mao, S.; Nawaz, A. A.; Lin, S.-C. S.; Lapsley, M. I.; Zhao, Y.; McCoy, J. P.; El-Deiry, W. S.; Huang, T. J. An Integrated, Multiparametric Flow Cytometry Chip Using "Microfluidic Drifting" Based Three-Dimensional Hydrodynamic Focusing Biomicrofluidics 2012, 6, 024113
    • (2012) Biomicrofluidics , vol.6 , pp. 024113
    • Mao, S.1    Nawaz, A.A.2    Lin, S.-C.S.3    Lapsley, M.I.4    Zhao, Y.5    McCoy, J.P.6    El-Deiry, W.S.7    Huang, T.J.8
  • 47
    • 65649085217 scopus 로고    scopus 로고
    • Microfluidic Mixing under Low Frequency Vibration
    • Oberti, S.; Neild, A.; Ng, T. W. Microfluidic Mixing under Low Frequency Vibration Lab Chip 2009, 9, 1435-1438
    • (2009) Lab Chip , vol.9 , pp. 1435-1438
    • Oberti, S.1    Neild, A.2    Ng, T.W.3
  • 48
    • 69549109749 scopus 로고    scopus 로고
    • A Millisecond Micromixer via Single-Bubble-Based Acoustic Streaming
    • Ahmed, D.; Mao, X. L.; Shi, J. J.; Juluri, B. K.; Huang, T. J. A Millisecond Micromixer via Single-Bubble-Based Acoustic Streaming Lab Chip 2009, 9, 2738-2741
    • (2009) Lab Chip , vol.9 , pp. 2738-2741
    • Ahmed, D.1    Mao, X.L.2    Shi, J.J.3    Juluri, B.K.4    Huang, T.J.5
  • 49
    • 70449526406 scopus 로고    scopus 로고
    • A Fast Microfluidic Mixer Based on Acoustically Driven Sidewall-Trapped Microbubbles
    • Ahmed, D.; Mao, X. L.; Juluri, B. K.; Huang, T. J. A Fast Microfluidic Mixer Based on Acoustically Driven Sidewall-Trapped Microbubbles Microfluid. Nanofluid. 2009, 7, 727-731
    • (2009) Microfluid. Nanofluid. , vol.7 , pp. 727-731
    • Ahmed, D.1    Mao, X.L.2    Juluri, B.K.3    Huang, T.J.4
  • 50
    • 84867531040 scopus 로고    scopus 로고
    • A Single-Layer, Planar, Optofluidic Switch Powered by Acoustically Driven, Oscillating Microbubbles
    • Huang, P. H.; Lapsley, M. I.; Ahmed, D.; Chen, Y. C.; Wang, L.; Huang, T. J. A Single-Layer, Planar, Optofluidic Switch Powered by Acoustically Driven, Oscillating Microbubbles Appl. Phys. Lett. 2012, 101, 141101
    • (2012) Appl. Phys. Lett. , vol.101 , pp. 141101
    • Huang, P.H.1    Lapsley, M.I.2    Ahmed, D.3    Chen, Y.C.4    Wang, L.5    Huang, T.J.6
  • 52
    • 84872059927 scopus 로고    scopus 로고
    • Tunable, Pulsatile Chemical Gradient Generation via Acoustically Driven Oscillating Bubbles
    • Ahmed, D.; Chan, C. Y.; Lin, S. C. S.; Muddana, H. S.; Nama, N.; Benkovic, S. J.; Huang, T. J. Tunable, Pulsatile Chemical Gradient Generation via Acoustically Driven Oscillating Bubbles Lab Chip 2013, 13, 328-331
    • (2013) Lab Chip , vol.13 , pp. 328-331
    • Ahmed, D.1    Chan, C.Y.2    Lin, S.C.S.3    Muddana, H.S.4    Nama, N.5    Benkovic, S.J.6    Huang, T.J.7
  • 54
    • 38849133041 scopus 로고    scopus 로고
    • Focusing Microparticles in a Microfluidic Channel with Standing Surface Acoustic Wave (SSAW)
    • Shi, J.; Mao, X.; Ahmed, D.; Colletti, A.; Huang, T. J. Focusing Microparticles in a Microfluidic Channel with Standing Surface Acoustic Wave (SSAW) Lab Chip 2008, 8, 221-223
    • (2008) Lab Chip , vol.8 , pp. 221-223
    • Shi, J.1    Mao, X.2    Ahmed, D.3    Colletti, A.4    Huang, T.J.5
  • 56
    • 0032047248 scopus 로고    scopus 로고
    • Microfluidic Motion Generation with Acoustic Waves
    • Zhu, X.; Kim, E. S. Microfluidic Motion Generation with Acoustic Waves Sensor Actuat. A: Phys. 1998, 66, 355-360
    • (1998) Sensor Actuat. A: Phys. , vol.66 , pp. 355-360
    • Zhu, X.1    Kim, E.S.2
  • 59
    • 34547855540 scopus 로고    scopus 로고
    • Prediction of Shear Damage of Plasmid DNA in Pump and Centrifuge Operations Using an Ultra Scale-Down Device
    • Zhang, H.; Kong, S.; Booth, A.; Boushaba, R.; Levy, M. S.; Hoare, M. Prediction of Shear Damage of Plasmid DNA in Pump and Centrifuge Operations Using an Ultra Scale-Down Device Biotechnol. Prog. 2007, 23, 858-865
    • (2007) Biotechnol. Prog. , vol.23 , pp. 858-865
    • Zhang, H.1    Kong, S.2    Booth, A.3    Boushaba, R.4    Levy, M.S.5    Hoare, M.6
  • 60
    • 67749102274 scopus 로고    scopus 로고
    • Stabilization of Naked and Condensed Plasmid DNA against Degradation Induced by Ultrasounds and High-Shear Vortices
    • Wu, M. L.; Freitas, S. S.; Monteiro, G. A.; Prazeres, D. M. F.; Santos, J. A. L. Stabilization of Naked and Condensed Plasmid DNA against Degradation Induced by Ultrasounds and High-Shear Vortices Biotechnol. Appl. Biochem. 2009, 53, 237-246
    • (2009) Biotechnol. Appl. Biochem. , vol.53 , pp. 237-246
    • Wu, M.L.1    Freitas, S.S.2    Monteiro, G.A.3    Prazeres, D.M.F.4    Santos, J.A.L.5
  • 61
    • 0024828793 scopus 로고
    • Ultrasonic Degradation of DNA
    • Elsner, H. I.; Lindblad, E. B. Ultrasonic Degradation of DNA DNA 1989, 8, 697-701
    • (1989) DNA , vol.8 , pp. 697-701
    • Elsner, H.I.1    Lindblad, E.B.2
  • 62
    • 0023425478 scopus 로고
    • Acoustic Cavitation and the Safety of Diagnostic Ultrasound
    • Carstensen, E. L. Acoustic Cavitation and the Safety of Diagnostic Ultrasound Ultrasound Med. Biol. 1987, 13, 597-606
    • (1987) Ultrasound Med. Biol. , vol.13 , pp. 597-606
    • Carstensen, E.L.1
  • 64
    • 19444372923 scopus 로고    scopus 로고
    • A Two-Stage Poly(ethylenimine)-Mediated Cytotoxicity: Implications for Gene Transfer/Therapy
    • Moghimi, S. M.; Symonds, P.; Murray, J. C.; Hunter, A. C.; Debska, G.; Szewczyk, A. A Two-Stage Poly(ethylenimine)-Mediated Cytotoxicity: Implications for Gene Transfer/Therapy Mol. Ther. 2005, 11, 990-995
    • (2005) Mol. Ther. , vol.11 , pp. 990-995
    • Moghimi, S.M.1    Symonds, P.2    Murray, J.C.3    Hunter, A.C.4    Debska, G.5    Szewczyk, A.6
  • 65
    • 84883309282 scopus 로고    scopus 로고
    • Mass Production of Highly Monodisperse Polymeric Nanoparticles by Parallel Flow Focusing System
    • Kang, X.; Luo, C.; Wei, Q.; Xiong, C.; Chen, Q.; Chen, Y.; Ouyang, Q. Mass Production of Highly Monodisperse Polymeric Nanoparticles by Parallel Flow Focusing System Microfluid. Nanofluid. 2013, 1-9
    • (2013) Microfluid. Nanofluid. , pp. 1-9
    • Kang, X.1    Luo, C.2    Wei, Q.3    Xiong, C.4    Chen, Q.5    Chen, Y.6    Ouyang, Q.7
  • 66
    • 38849164275 scopus 로고    scopus 로고
    • Microfluidic Large-Scale Integration on a Chip for Mass Production of Monodisperse Droplets and Particles
    • Nisisako, T.; Torii, T. Microfluidic Large-Scale Integration on a Chip for Mass Production of Monodisperse Droplets and Particles Lab Chip 2008, 8, 287-293
    • (2008) Lab Chip , vol.8 , pp. 287-293
    • Nisisako, T.1    Torii, T.2
  • 67
    • 39549086017 scopus 로고    scopus 로고
    • Prediction of Diffusion Coefficients of Plasmids
    • Prazeres, D. M. F. Prediction of Diffusion Coefficients of Plasmids Biotechnol. Bioeng. 2008, 99, 1040-1044
    • (2008) Biotechnol. Bioeng. , vol.99 , pp. 1040-1044
    • Prazeres, D.M.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.