Three-dimensional hydrodynamic focusing in two-layer polydimethylsiloxane (PDMS) microchannels

Journal of Micromechanics and Microengineering

Volumn 17, Issue 8, 2007, Pages 1479-1486

  Chang, Chih Chang ^a   Huang, Zhi Xiong ^a   Yang, Ruey Jen ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ASPECT RATIO; HYDRODYNAMICS; MICROFLUIDICS; PARAFFINS; REYNOLDS NUMBER;

CELL/PARTICLE COUNTING; MICROCHANNEL STRUCTURE;

MICROCHANNELS;

EID: 34547663221     PISSN: 09601317     EISSN: 13616439     Source Type: Journal    
DOI: 10.1088/0960-1317/17/8/009     Document Type: Article

References (38)

1. Stone H A, Stroock A D and Ajdari A 2004 Engineering flows in small devices: microfluidics towards a lab-on-a-chip Annu. Rev. Fluid Mech. 36 381-411
2. Dittrich P S, Tachikawa K and Manz A 2006 Micro total analysis systems. Latest advancements and trends Anal. Chem. 78 3887-907
3. Whitesides G M 2006 The origins and the future of microfluidics Nature 442 368-73
4. Janasek D, Franzke J and Manz A 2006 Scaling and the design of miniaturized chemical analysis systems Nature 442 374-80
5. Crosland-Taylor P 1953 A device for counting small particles suspended in fluid through a tube Nature 17 37-8
6. Jacobson S C and Ramsey J M 1997 Electrokinetic focusing in microfabricated channel structures Anal. Chem. 69 3212-7
7. Yang R-J, Chang C-C, Huang S-B and Lee G-B 2005 A new focusing model and switching approach for electrokinetic flow inside microchannels J. Micromech. Microeng. 15 2141-8
8. Schrum D P, Culbertson C T, Jacobson S C and Ramsey J M 1999 Microchip flow cytometry using electrokinetic focusing Anal. Chem. 71 4173-7
9. Huh D, Gu W, Kamotani Y, Grotberg J B and Takayama S 2005 Microfluidics for flow cytometric analysis of cells and particles Physiol. Meas. 26 R73-98
10. Fu L-M, Yang R-J, Lin C-H, Pan Y-J and Lee G-B 2004 Electrokinetically- driven microflow cytometers with integrated fiber optics for on-line cell/particle collection Anal. Chim. Acta 507 163-9
11. Lee G-B, Lin C-H and Chang S C 2005 Micromachined multi-cell-line flow cytometer for cell/particle counting/sorting J. Micromech. Microeng. 15 447-54
12. Wong P K, Lee Y-K and Ho C-M 2003 Deformation of DNA molecules by hydrodynamic focusing J. Fluid Mech. 497 55-65
13. Fu L-M, Yang R-J, Lee G-B and Pan Y-J 2003 Multiple injection techniques for microfluidic sample handling Electrophoresis 24 3026-32
14. Knight J B, Vishwanath A, Brody J P and Austin R H 1998 Hydrodynamic focusing on a silicon chip: mixing nanoliters in microseconds Phys. Rev. Lett. 80 3863-6
15. Pollack L, Tate M W, Darnton N C, Knight J B, Gruner S M, Eaton W A and Austin R H 1999 Compactness of the denatured state of a fast-folding protein measured by submillisecond small-angle x-ray scattering Proc. Natl Acad. Sci. USA 96 10115-7
16. Hertzog D E, Michalet X, Jager M, Kong X, Santiago J G, Weiss S and Bakajin O 2004 Femtomole mixer for microsecond kinetic studies of protein folding Anal. Chem. 76 7169-78
17. Wolfe D, Conroy R, Garstecki P, Mayers B, Fischbach M, Paul K, Prentiss M and Whitesides G M 2004 Dynamic control of liquid-core/liquid-cladding optical waveguides Proc. Natl Acad. Sci. USA 101 12434-8
18. Vezenov D V, Mayers B T, Wolfe D B and Whitesides G M 2005 Integrated fluorescent light source for optofluidic applications Appl. Phys. Lett. 86 041104
19. Anna S L, Bontoux N and Stone H A 2003 Formation of dispersions using 'flow focusing' in microchannels Appl. Phys. Lett. 82 364-6
20. Gãn-Calvo A M and Gordillo J M 2001 Perfectly monodisperse microbubbling by capillary flow focusing Phys. Rev. Lett. 87 274501
21. Garstecki P, Gitlin I, DiLuzio W, Whitesides G M, Kumacheva E and Stone H A 2004 Formation of monodisperse bubbles in a microfluidic flow-focusing device Appl. Phys. Lett. 85 2649-51
22. Martín-Banderas L, Flores-Mosquera M, Riesco-Chueca P, Rodríguez-Gil A, Cebolla, Chvez S and Gãn-Calvo A M 2005 Flow focusing: a versatile technology to produce size-controlled and specific-morphology microparticles Small 1 688-92
23. Lee G-B, Chang C-C, Huang S-B and Yang R-J 2006 The hydrodynamic focusing effect inside rectangular microchannels J. Micromech. Microeng. 16 1024-32
24. Morgan H, Holmes D and Green N G 2003 3D focusing of nanoparticles in microfluidic channels IEE Proc. Nanobiotechnol. 150 76-80
25. Yu C, Vykoukal J, Vykoukal D M, Schwartz J A, Shi L and Gascoyne P R C 2005 A three-dimensional dielectrophoretic particle focusing channel for microcytometry application J. Microelectromech. Syst. 14 480-7
26. Holmes D, Morgan H and Green N G 2006 High throughput particle analysis: combining dielectrophoretic particle focusing with confocal optical detection Biosens. Bioelectron. 21 1621-30
27. Lin C-H, Lee G-B, Fu L-M and Hwey B H 2004 Vertical focusing devices utilizing dielectrophoretic force and its application on microflow cytometer J. Microelectromech. Syst. 13 923-32
28. Yang R, Feeback D L and Wang W 2005 Microfabrication and test of a three-dimensional polymer hydro-focusing unit for flow cytometry applications Sensors Actuators A 118 259-67
29. Sundararajan N, Pio M S, Lee L P and Berlin A A 2004 Three-dimensional hydrodynamic focusing in polydimethylsiloxane (PDMS) microchannels J. Microelectromech. Syst. 13 559-67
30. Simonnet C and Groisman A 2005 Two-dimensional hydrodynamic focusing in a simple microfluidic device Appl. Phys. Lett. 87 114104
31. Morgan H and Green N G 2003 AC Elecrokinetics: Colloids and Nanoparticles (Baldock, UK: Research Studies Press Ltd)
32. Klank H, Goranović G, Kutter J P, Gjelstrup H, Michelsen J and Westergaard C H 2002 PIV measurements in a microfluidic 3D-sheathing structure with three-dimensional flow behaviour J. Micromech. Microeng. 12 862-9
33. Chung S, Park S J, Kim J K, Chung C, Han D C and Chang J K 2003 Plastic microchip flow cytometer based on 2- and 3-dimensional hydrodynamic flow focusing Microsyst. Technol. 9 525-33
34. Utada A S, Lorenceau E, Link D R, Kaplan P D, Stone H A and Weitz D A 2005 Monodisperse double emulsions generated from a microcapillary device Science 308 537-41
35. Takeuchi S, Garstecki P, Weibel D B and Whitesides G M 2005 An axisymmetric flow-focusing microfluidic device Adv. Mater. 17 1067-72
36. Duffy D C, McDonald J C, Schueller O J A and Whitesides G M 1998 Rapid prototyping of microfluidic systems in poly(dimethylsiloxane) Anal. Chem. 70 4974-84
37. Chorin A J 1967 A numerical method for solving incompressible viscous flow problem J. Comput. Phys. 2 12-26
38. Van Dilla M A 1985 Flow Cytometry: Instrumentation and Data Analysis (London: Academic)