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Volumn 289, Issue 5, 2014, Pages 2839-2851

Pannexin 3 inhibits proliferation of osteoprogenitor cells by regulating Wnt and p21 signaling

Author keywords

[No Author keywords available]

Indexed keywords

ATP; CALCIUM INTRACELLULAR RELEASE; CELL PROLIFERATION; HEMICHANNEL AND ER CA2+ CHANNEL; INTRACELLULAR ATP AND CA2+ LEVELS; P21; PANNEXIN; PANNEXIN 3; WNT SIGNALING; WNT/Β-CATENIN SIGNALING;

EID: 84893503166     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.523241     Document Type: Article
Times cited : (46)

References (64)
  • 1
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling and disease
    • Clevers, H., and Nusse, R. (2012) Wnt/β-catenin signaling and disease. Cell 149, 1192-1205
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 2
    • 0037205007 scopus 로고    scopus 로고
    • The promise and perils of Wnt signaling through β-catenin
    • Moon, R. T., Bowerman, B., Boutros, M., and Perrimon, N. (2002) The promise and perils of Wnt signaling through β-catenin. Science 296, 1644-1646
    • (2002) Science , vol.296 , pp. 1644-1646
    • Moon, R.T.1    Bowerman, B.2    Boutros, M.3    Perrimon, N.4
  • 3
    • 0041695485 scopus 로고    scopus 로고
    • A second canon. Functions and mechanisms of β-catenin-independent Wnt signaling
    • Veeman, M. T., Axelrod, J. D., and Moon, R. T. (2003) A second canon. Functions and mechanisms of β-catenin-independent Wnt signaling. Dev. Cell 5, 367-377
    • (2003) Dev. Cell , vol.5 , pp. 367-377
    • Veeman, M.T.1    Axelrod, J.D.2    Moon, R.T.3
  • 4
    • 0037155691 scopus 로고    scopus 로고
    • Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism
    • Liu, C, Li, Y., Semenov, M., Han, C, Baeg, G. H., Tan, Y., Zhang, Z., Lin, X., and He, X. (2002) Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 108, 837-847
    • (2002) Cell , vol.108 , pp. 837-847
    • Liu, C.1    Li, Y.2    Semenov, M.3    Han, C.4    Baeg, G.H.5    Tan, Y.6    Zhang, Z.7    Lin, X.8    He, X.9
  • 7
    • 34250827150 scopus 로고    scopus 로고
    • Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
    • Bilic, J., Huang, Y.-L., Davidson, G., Zimmermann, T., Cruciat, C.-M., Bienz, M., and Niehrs, C. (2007) Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation. Science 316, 1619-1622
    • (2007) Science , vol.316 , pp. 1619-1622
    • Bilic, J.1    Huang, Y.-L.2    Davidson, G.3    Zimmermann, T.4    Cruciat, C.-M.5    Bienz, M.6    Niehrs, C.7
  • 9
    • 0345343608 scopus 로고    scopus 로고
    • Nuclear localization of β-catenin by interaction with transcription factor LEF-1
    • Huber, O., Korn, R., McLaughlin, J., Ohsugi, M., Herrmann, B. G., and Kemler, R. (1996) Nuclear localization of β-catenin by interaction with transcription factor LEF-1. Mech. Dev. 59, 3-10
    • (1996) Mech. Dev. , vol.59 , pp. 3-10
    • Huber, O.1    Korn, R.2    McLaughlin, J.3    Ohsugi, M.4    Herrmann, B.G.5    Kemler, R.6
  • 10
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross, D. A., Alessi, D. R., Cohen, P., Andjelkovich, M., and Hemmings, B. A. (1995) Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378, 785-789
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 12
    • 46449131544 scopus 로고    scopus 로고
    • PTH/cAMP/PKA signaling facilitates canonical Wnt signaling via inactivation of glycogen synthase kinase-3β in osteoblastic Saos-2 cells
    • Suzuki, A., Ozono, K., Kubota, T., Kondou, H, Tachikawa, K., and Michigami, T. (2008) PTH/cAMP/PKA signaling facilitates canonical Wnt signaling via inactivation of glycogen synthase kinase-3β in osteoblastic Saos-2 cells. J. Cell. Biochem. 104, 304-317
    • (2008) J. Cell. Biochem. , vol.104 , pp. 304-317
    • Suzuki, A.1    Ozono, K.2    Kubota, T.3    Kondou, H.4    Tachikawa, K.5    Michigami, T.6
  • 13
    • 26444486391 scopus 로고    scopus 로고
    • Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase stabilizes β-catenin through inhibition of its ubiquitination
    • Hino, S., Tanji, C, Nakayama, K. I., and Kikuchi, A. (2005) Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase stabilizes β-catenin through inhibition of its ubiquitination. Mol. Cell Biol. 25, 9063-9072
    • (2005) Mol. Cell Biol. , vol.25 , pp. 9063-9072
    • Hino, S.1    Tanji, C.2    Nakayama, K.I.3    Kikuchi, A.4
  • 21
    • 33750301324 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation
    • Mak, K. K., Chen, M.-H., Day, T. F., Chuang, P.-T., and Yang, Y. (2006) Wnt/β-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation. Development 133, 3695-3707
    • (2006) Development , vol.133 , pp. 3695-3707
    • Mak, K.K.1    Chen, M.-H.2    Day, T.F.3    Chuang, P.-T.4    Yang, Y.5
  • 26
    • 33749003106 scopus 로고    scopus 로고
    • Pannexin expression in the cerebellum
    • Ray, A., Zoidl, G., Wahle, P., and Dermietzel, R. (2006) Pannexin expression in the cerebellum. Cerebellum 5, 189-192
    • (2006) Cerebellum , vol.5 , pp. 189-192
    • Ray, A.1    Zoidl, G.2    Wahle, P.3    Dermietzel, R.4
  • 27
    • 27644494198 scopus 로고    scopus 로고
    • Pannexin1 and Pannexin2 expression in the developing and mature rat brain
    • Vogt, A., Hormuzdi, S. G., and Monyer, H. (2005) Pannexin1 and Pannexin2 expression in the developing and mature rat brain. Brain Res. Mol. Brain Res. 141, 113-120
    • (2005) Brain Res. Mol. Brain Res. , vol.141 , pp. 113-120
    • Vogt, A.1    Hormuzdi, S.G.2    Monyer, H.3
  • 28
    • 36549084087 scopus 로고    scopus 로고
    • Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins
    • Penuela, S., Bhalla, R., Gong, X. Q., Cowan, K. N, Celetti, S. J., Cowan, B. J., Bai, D., Shao, Q., and Laird, D. W. (2007) Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins. J. Cell Sci. 120, 3772-3783
    • (2007) J. Cell Sci. , vol.120 , pp. 3772-3783
    • Penuela, S.1    Bhalla, R.2    Gong, X.Q.3    Cowan, K.N.4    Celetti, S.J.5    Cowan, B.J.6    Bai, D.7    Shao, Q.8    Laird, D.W.9
  • 30
    • 77953319991 scopus 로고    scopus 로고
    • Pannexin 3 regulates intracellular ATP/cAMP levels and promotes chondrocyte differentiation
    • Iwamoto, T., Nakamura, T., Doyle, A., Ishikawa, M., De Vega, S., Fukumoto, S., and Yamada, Y. (2010) Pannexin 3 regulates intracellular ATP/cAMP levels and promotes chondrocyte differentiation. J. Biol. Chem. 285, 18948-18958
    • (2010) J. Biol. Chem. , vol.285 , pp. 18948-18958
    • Iwamoto, T.1    Nakamura, T.2    Doyle, A.3    Ishikawa, M.4    De Vega, S.5    Fukumoto, S.6    Yamada, Y.7
  • 31
    • 67650985957 scopus 로고    scopus 로고
    • Critical roles of the TGF-β type I receptor ALK5 in perichondrial formation and function, cartilage integrity, and osteoblast differentiation during growth plate development
    • Matsunobu, T., Torigoe, K., Ishikawa, M., De Vega, S., Kulkarni, A. B., Iwamoto, Y., and Yamada, Y. (2009) Critical roles of the TGF-β type I receptor ALK5 in perichondrial formation and function, cartilage integrity, and osteoblast differentiation during growth plate development. Dev. Biol. 332, 325-338
    • (2009) Dev. Biol. , vol.332 , pp. 325-338
    • Matsunobu, T.1    Torigoe, K.2    Ishikawa, M.3    De Vega, S.4    Kulkarni, A.B.5    Iwamoto, Y.6    Yamada, Y.7
  • 32
    • 0026537862 scopus 로고
    • A pitfall of using a second plasmid to determine transfection efficiency
    • Farr, A., and Roman, A. (1992) A pitfall of using a second plasmid to determine transfection efficiency. Nucleic Acids Res. 20, 920
    • (1992) Nucleic Acids Res. , vol.20 , pp. 920
    • Farr, A.1    Roman, A.2
  • 34
    • 84934434613 scopus 로고    scopus 로고
    • Assessing new bone formation in neonatal calvarial organ cultures
    • Mohammad, K. S., Chirgwin, J. M., and Guise, T. A. (2008) Assessing new bone formation in neonatal calvarial organ cultures. Methods Mol. Biol. 455, 37-50
    • (2008) Methods Mol. Biol. , vol.455 , pp. 37-50
    • Mohammad, K.S.1    Chirgwin, J.M.2    Guise, T.A.3
  • 35
    • 77951841805 scopus 로고    scopus 로고
    • Evaluation of critical size defects of mouse calvarial bone. An organ culture study
    • Wu, X., Downes, S., and Watts, D. C. (2010) Evaluation of critical size defects of mouse calvarial bone. An organ culture study. Microsc. Res. Tech. 73, 540-547
    • (2010) Microsc. Res. Tech. , vol.73 , pp. 540-547
    • Wu, X.1    Downes, S.2    Watts, D.C.3
  • 36
    • 0034782842 scopus 로고    scopus 로고
    • The frequency of common progenitors for adipocytes and osteoblasts and of committed and restricted adipocyte and osteoblast progenitors in fetal rat calvaria cell populations
    • Bellows, C. G., and Heersche, J. N (2001) The frequency of common progenitors for adipocytes and osteoblasts and of committed and restricted adipocyte and osteoblast progenitors in fetal rat calvaria cell populations. J. Bone Miner. Res. 16, 1983-1993
    • (2001) J. Bone Miner. Res. , vol.16 , pp. 1983-1993
    • Bellows, C.G.1    Heersche, J.N.2
  • 37
    • 0020535398 scopus 로고
    • Osteoblasts isolated from mouse calvaria initiate matrix mineralization in culture
    • Ecarot-Charrier, B., Glorieux, F. H, Van Der Rest, M., and Pereira, G. (1983) Osteoblasts isolated from mouse calvaria initiate matrix mineralization in culture. J. Cell Biol. 96, 639-643
    • (1983) J. Cell Biol. , vol.96 , pp. 639-643
    • Ecarot-Charrier, B.1    Glorieux, F.H.2    Van Der Rest, M.3    Pereira, G.4
  • 38
    • 40949128686 scopus 로고    scopus 로고
    • Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways
    • Raucci, A., Bellosta, P., Grassi, R., Basilico, C, and Mansukhani, A. (2008) Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways. J. Cell Physiol. 215, 442-451
    • (2008) J. Cell Physiol. , vol.215 , pp. 442-451
    • Raucci, A.1    Bellosta, P.2    Grassi, R.3    Basilico, C.4    Mansukhani, A.5
  • 39
    • 77954069774 scopus 로고    scopus 로고
    • N-cadherin negatively regulates osteoblast proliferation and survival by antagonizing Wnt, ERK and PI3K/Akt signalling
    • Haÿ, E., Nouraud, A., and Marie, P. J. (2009) N-cadherin negatively regulates osteoblast proliferation and survival by antagonizing Wnt, ERK and PI3K/Akt signalling. PLoS One 4, e8284
    • (2009) PLoS One , vol.4
    • Haÿ, E.1    Nouraud, A.2    Marie, P.J.3
  • 41
    • 40349100516 scopus 로고    scopus 로고
    • Regulation of bone metabolism by pathogenic mutations and polymorphism in the LRP5-Wnt signaling genes
    • Urano, T. (2007) [Regulation of bone metabolism by pathogenic mutations and polymorphism in the LRP5-Wnt signaling genes]. Nihon Rinsho 65, (Suppl. 9) 95-100
    • (2007) Nihon Rinsho , vol.65 , Issue.SUPPL. 9 , pp. 95-100
    • Urano, T.1
  • 42
    • 79955557954 scopus 로고    scopus 로고
    • Wnt4 activates the canonical β-catenin pathway and regulates negatively myostatin. Functional implication in myogenesis
    • Bernardi, H., Gay, S., Fedon, Y., Vernus, B., Bonnieu, A., and Bacou, F. (2011) Wnt4 activates the canonical β-catenin pathway and regulates negatively myostatin. Functional implication in myogenesis. Am. J. Physiol. Cell Physiol. 300, C1122-C1138
    • (2011) Am. J. Physiol. Cell Physiol. , vol.300
    • Bernardi, H.1    Gay, S.2    Fedon, Y.3    Vernus, B.4    Bonnieu, A.5    Bacou, F.6
  • 43
    • 27844541752 scopus 로고    scopus 로고
    • Cross-talk between Wnt and bone morphogenetic protein 2 (BMP-2) signaling in differentiation pathway of C2C12 myoblasts
    • Nakashima, A., Katagiri, T., and Tamura, M. (2005) Cross-talk between Wnt and bone morphogenetic protein 2 (BMP-2) signaling in differentiation pathway of C2C12 myoblasts. J. Biol. Chem. 280, 37660-37668
    • (2005) J. Biol. Chem. , vol.280 , pp. 37660-37668
    • Nakashima, A.1    Katagiri, T.2    Tamura, M.3
  • 44
    • 70349932747 scopus 로고    scopus 로고
    • Towards an integrated view of Wnt signaling in development
    • Van Amerongen, R., and Nusse, R. (2009) Towards an integrated view of Wnt signaling in development. Development 136, 3205-3214
    • (2009) Development , vol.136 , pp. 3205-3214
    • Van Amerongen, R.1    Nusse, R.2
  • 45
    • 5044228112 scopus 로고    scopus 로고
    • Wnt signaling in osteoblasts and bone diseases
    • Westendorf, J. J., Kahler, R. A., and Schroeder, T. M. (2004) Wnt signaling in osteoblasts and bone diseases. Gene 341, 19-39
    • (2004) Gene , vol.341 , pp. 19-39
    • Westendorf, J.J.1    Kahler, R.A.2    Schroeder, T.M.3
  • 46
    • 0242468744 scopus 로고    scopus 로고
    • Regulation and organization of adenylyl cyclases and cAMP
    • Cooper, D. M. (2003) Regulation and organization of adenylyl cyclases and cAMP. Biochem. J. 375, 517-529
    • (2003) Biochem. J. , vol.375 , pp. 517-529
    • Cooper, D.M.1
  • 47
    • 0037157816 scopus 로고    scopus 로고
    • ATP regulates the differentiation of mammalian skeletal muscle by activation of a P2X5 receptor on satellite cells
    • Ryten, M., Dunn, P. M., Neary, J. T., and Burnstock, G. (2002) ATP regulates the differentiation of mammalian skeletal muscle by activation of a P2X5 receptor on satellite cells. J. Cell Biol. 158, 345-355
    • (2002) J. Cell Biol. , vol.158 , pp. 345-355
    • Ryten, M.1    Dunn, P.M.2    Neary, J.T.3    Burnstock, G.4
  • 48
    • 0024614795 scopus 로고
    • The cyclic AMP-mediated stimulation of cell proliferation
    • Dumont, J. E., Jauniaux, J. C, and Roger, P. P. (1989) The cyclic AMP-mediated stimulation of cell proliferation. Trends Biochem. Sci. 14, 67-71
    • (1989) Trends Biochem. Sci. , vol.14 , pp. 67-71
    • Dumont, J.E.1    Jauniaux, J.C.2    Roger, P.P.3
  • 49
    • 0036717416 scopus 로고    scopus 로고
    • The cyclin D1 and cyclin A genes are targets of activated PTH/PTHrP receptors in Jansen's metaphyseal chondrodysplasia
    • Beier, F., and Lu Valle, P. (2002) The cyclin D1 and cyclin A genes are targets of activated PTH/PTHrP receptors in Jansen's metaphyseal chondrodysplasia. Mol. Endocrinol. 16, 2163-2173
    • (2002) Mol. Endocrinol. , vol.16 , pp. 2163-2173
    • Beier, F.1    Lu Valle, P.2
  • 52
    • 20144379460 scopus 로고    scopus 로고
    • Smad pathway-specific transcriptional regulation of the cell cycle inhibitor p21 (WAF1/Cip1)
    • Pardali, K., Kowanetz, M., Heldin, C.-H, and Moustakas, A. (2005) Smad pathway-specific transcriptional regulation of the cell cycle inhibitor p21 (WAF1/Cip1). J. Cell Physiol. 204, 260-272
    • (2005) J. Cell Physiol. , vol.204 , pp. 260-272
    • Pardali, K.1    Kowanetz, M.2    Heldin, C.-H.3    Moustakas, A.4
  • 53
    • 29244446792 scopus 로고    scopus 로고
    • Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by β-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT
    • Almeida, M., Han, L., Bellido, T., Manolagas, S. C, and Kousteni, S. (2005) Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by β-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT. J. Biol. Chem. 280, 41342-41351
    • (2005) J. Biol. Chem. , vol.280 , pp. 41342-41351
    • Almeida, M.1    Han, L.2    Bellido, T.3    Manolagas, S.C.4    Kousteni, S.5
  • 54
    • 84862818296 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling changes C2C12 myoblast proliferation and differentiation by inducing Id3 expression
    • Zhang, L., Shi, S., Zhang, J., Zhou, F., and Ten Dijke, P. (2012) Wnt/β-catenin signaling changes C2C12 myoblast proliferation and differentiation by inducing Id3 expression. Biochem. Biophys. Res. Commun. 419, 83-88
    • (2012) Biochem. Biophys. Res. Commun. , vol.419 , pp. 83-88
    • Zhang, L.1    Shi, S.2    Zhang, J.3    Zhou, F.4    Ten Dijke, P.5
  • 55
    • 0142241118 scopus 로고    scopus 로고
    • BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by aWnt autocrine loop
    • Rawadi, G., Vayssière, B., Dunn, F., Baron, R., and Roman-Roman, S. (2003) BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by aWnt autocrine loop. J. Bone Miner. Res. 18, 1842-1853
    • (2003) J. Bone Miner. Res. , vol.18 , pp. 1842-1853
    • Rawadi, G.1    Vayssière, B.2    Dunn, F.3    Baron, R.4    Roman-Roman, S.5
  • 56
    • 0035479835 scopus 로고    scopus 로고
    • New aspects of Wnt signaling pathways in higher vertebrates
    • Huelsken, J., and Birchmeier, W. (2001) New aspects of Wnt signaling pathways in higher vertebrates. Curr. Opin. Genet. Dev. 11, 547-553
    • (2001) Curr. Opin. Genet. Dev. , vol.11 , pp. 547-553
    • Huelsken, J.1    Birchmeier, W.2
  • 62
    • 30044441003 scopus 로고    scopus 로고
    • Calcium/calmodulin signaling controls osteoblast growth and differentiation
    • Zayzafoon, M. (2006) Calcium/calmodulin signaling controls osteoblast growth and differentiation. J. Cell Biochem. 97, 56-70
    • (2006) J. Cell Biochem. , vol.97 , pp. 56-70
    • Zayzafoon, M.1
  • 63
    • 34547897405 scopus 로고    scopus 로고
    • 2+ channel. From discovery to new signaling concepts
    • 2+ channel. From discovery to new signaling concepts. J. Neurochem. 102, 1426-1446
    • (2007) J. Neurochem. , vol.102 , pp. 1426-1446
    • Mikoshiba, K.1


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