Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis

Development

Volumn 131, Issue 21, 2004, Pages 5469-5480

  Kokubu, Chikara ^a,b   Heinzmann, Ulrich ^a   Kokubu, Tomoko ^a   Sakai, Norio ^b   Kubota, Takuo ^b   Kawai, Masanobu ^b   Wahl, Matthias B ^a   Galceran, Juan ^c   Grosschedl, Rudolf ^c   Ozono, Keiichi ^b   Imai, Kenji ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Lrp6; Mouse; Osteoporosis; Somitogenesis; Wnt signaling

Indexed keywords

ARGININE; BETA CATENIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; MEMBRANE PROTEIN; NOTCH RECEPTOR; TRYPTOPHAN; UNCLASSIFIED DRUG; WNT PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE MALFORMATION; BONE MASS; CODON; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GENE MUTATION; GENETIC COMPLEMENTATION; GENETIC CONSERVATION; GENOTYPE; HISTOPATHOLOGY; HOMOZYGOSITY; IN SITU HYBRIDIZATION; MOLECULAR CLONING; MOUSE; NEURAL TUBE; NICK END LABELING; NONHUMAN; OSSIFICATION; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SOMITE; TERATOLOGY;

AGING; ALLELES; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BETA CATENIN; BODY PATTERNING; CELL POLARITY; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; EMBRYO; FIBROBLASTS; LUMBOSACRAL REGION; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MUSCULOSKELETAL ABNORMALITIES; MUTATION; OSTEOGENESIS; PHENOTYPE; PROTO-ONCOGENE PROTEINS; RECEPTORS, LDL; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SOMITES; TRANS-ACTIVATORS; WNT PROTEINS;

ANIMALIA;

EID: 9444235153     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01405     Document Type: Article

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