Overexpression of metallothionein in the heart of transgenic mice suppresses doxorubicin cardiotoxicity

Journal of Clinical Investigation

Volumn 100, Issue 6, 1997, Pages 1501-1506

  Kang, Y James ^a   Chen, Van ^a   Yu, Anding ^a   Voss McCowan, Mildred ^b   Epstein, Paul N ^b  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Contractility; Creatine phosphokinase; Electron microscopy; Morphology; Transgene

Indexed keywords

CATALASE; DOXORUBICIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; METALLOTHIONEIN; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CARDIOTOXICITY; CELL PROTECTION; CONTROLLED STUDY; ELECTRON MICROSCOPY; GENE OVEREXPRESSION; HEART PROTECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

EID: 0030803635     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119672     Document Type: Article

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