-
1
-
-
33644748138
-
Peroxisome proliferator-activated receptor c agonists as therapy for chronic airway inflammation
-
Belvisi MG, Hele DJ, Birrell MA. Peroxisome proliferator-activated receptor c agonists as therapy for chronic airway inflammation. Eur J Pharmacol 2006; 533: 101-109.
-
(2006)
Eur J Pharmacol
, vol.533
, pp. 101-109
-
-
Belvisi, M.G.1
Hele, D.J.2
Birrell, M.A.3
-
2
-
-
0028972025
-
15-Deoxy-D12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARc
-
Forman BM, Tontonoz P, Chen J, et al. 15-Deoxy-D12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARc. Cell 1995; 83: 803-812.
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
Tontonoz, P.2
Chen, J.3
-
3
-
-
39449138164
-
Pleiotrophic and anti-inflammatory effects of pioglitazone precede the metabolic activity in type 2 diabetic patients with coronary artery disease
-
Forst T, Karagiannis E, Lübben G, et al. Pleiotrophic and anti-inflammatory effects of pioglitazone precede the metabolic activity in type 2 diabetic patients with coronary artery disease. Atherosclerosis 2008; 197: 311-317.
-
(2008)
Atherosclerosis
, vol.197
, pp. 311-317
-
-
Forst, T.1
Karagiannis, E.2
Lübben, G.3
-
4
-
-
0032505096
-
Ligand binding and co-activator assembly of the peroxisome proliferatoractivated receptor-c
-
Nolte RT, Wisely GB, Westin S, et al. Ligand binding and co-activator assembly of the peroxisome proliferatoractivated receptor-c. Nature 1998; 395: 137-143.
-
(1998)
Nature
, vol.395
, pp. 137-143
-
-
Nolte, R.T.1
Wisely, G.B.2
Westin, S.3
-
5
-
-
34548501244
-
Quantification of PPAR-c protein in monocyte/macrophages from healthy smokers and non-smokers: A possible direct effect of nicotine
-
Amoruso A, Bardelli C, Gunella G, et al. Quantification of PPAR-c protein in monocyte/macrophages from healthy smokers and non-smokers: a possible direct effect of nicotine. Life Sci 2007; 81: 906-915.
-
(2007)
Life Sci
, vol.81
, pp. 906-915
-
-
Amoruso, A.1
Bardelli, C.2
Gunella, G.3
-
6
-
-
33845970925
-
Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARc
-
Ghisletti S, Huang W, Ogawa S, et al. Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARc. Mol Cell 2007; 25: 57-70.
-
(2007)
Mol Cell
, vol.25
, pp. 57-70
-
-
Ghisletti, S.1
Huang, W.2
Ogawa, S.3
-
7
-
-
79959338163
-
PPARc stabilizes HO-1 mRNA in monocytes/macrophages which affects IFN-b expression
-
von Knethen A, Neb H, Morbitzer V, et al. PPARc stabilizes HO-1 mRNA in monocytes/macrophages which affects IFN-b expression. Free Radic Biol Med 2011; 51: 396-405.
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 396-405
-
-
Von Knethen, A.1
Neb, H.2
Morbitzer, V.3
-
8
-
-
66949155726
-
Deletion of PPARc in alveolar macrophages is associated with a Th-1 pulmonary inflammatory response
-
Malur A, McCoy AJ, Arce S, et al. Deletion of PPARc in alveolar macrophages is associated with a Th-1 pulmonary inflammatory response. J Immunol 2009; 182: 5816-5822.
-
(2009)
J Immunol
, vol.182
, pp. 5816-5822
-
-
Malur, A.1
McCoy, A.J.2
Arce, S.3
-
9
-
-
84865410948
-
Systemic analysis of PPARc in mouse macrophage populations reveals marked diversity in expression with critical roles in resolution of inflammation and airway immunity
-
Gautier EL, Chow A, Spanbroek R, et al. Systemic analysis of PPARc in mouse macrophage populations reveals marked diversity in expression with critical roles in resolution of inflammation and airway immunity. J Immunol 2012; 189: 2614-2624.
-
(2012)
J Immunol
, vol.189
, pp. 2614-2624
-
-
Gautier, E.L.1
Chow, A.2
Spanbroek, R.3
-
10
-
-
3543104442
-
PPAR-c agonists as therapy for diseases involving airway neutrophilia
-
Birrell MA, Patel HJ, McCluskie K, et al. PPAR-c agonists as therapy for diseases involving airway neutrophilia. Eur Respir J 2004; 24: 18-23.
-
(2004)
Eur Respir J
, vol.24
, pp. 18-23
-
-
Birrell, M.A.1
Patel, H.J.2
McCluskie, K.3
-
11
-
-
41649116684
-
Pioglitazone is as effective as dexamethasone in a cockroach allergen-induced murine model of asthma
-
Narala VR, Ranga R, Smith MR, et al. Pioglitazone is as effective as dexamethasone in a cockroach allergen-induced murine model of asthma. Respir Res 2007; 8: 90.
-
(2007)
Respir Res
, vol.8
, pp. 90
-
-
Narala, V.R.1
Ranga, R.2
Smith, M.R.3
-
12
-
-
34250351211
-
PPARc-dependent regulation of human macrophages in phagocytosis of apoptotic cells
-
Majai G, Sarang Z, Csomós K, et al. PPARc-dependent regulation of human macrophages in phagocytosis of apoptotic cells. Eur J Immunol 2007; 37: 1343-1354.
-
(2007)
Eur J Immunol
, vol.37
, pp. 1343-1354
-
-
Majai, G.1
Sarang, Z.2
Csomós, K.3
-
13
-
-
0012626868
-
New concepts in chronic obstructive pulmonary disease
-
Barnes PJ. New concepts in chronic obstructive pulmonary disease. Annu Rev Med 2003; 54: 113-129.
-
(2003)
Annu Rev Med
, vol.54
, pp. 113-129
-
-
Barnes, P.J.1
-
14
-
-
10644266789
-
Mediators of chronic obstructive pulmonary disease
-
Barnes PJ. Mediators of chronic obstructive pulmonary disease. Pharmacol Rev 2004; 56: 515-548.
-
(2004)
Pharmacol Rev
, vol.56
, pp. 515-548
-
-
Barnes, P.J.1
-
15
-
-
2942720573
-
The nature of small-airway obstruction in chronic obstructive pulmonary disease
-
Hogg JC, Chu F, Utokaparch S, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2004; 350: 2645-2653.
-
(2004)
N Engl J Med
, vol.350
, pp. 2645-2653
-
-
Hogg, J.C.1
Chu, F.2
Utokaparch, S.3
-
16
-
-
79953085365
-
Smoking status and anti-inflammatory macrophages in bronchoalveolar lavage and induced sputum in COPD
-
Kunz LI, Lapperre TS, Snoeck-Stroband JB, et al. Smoking status and anti-inflammatory macrophages in bronchoalveolar lavage and induced sputum in COPD. Respir Res 2011; 12: 34.
-
(2011)
Respir Res
, vol.12
, pp. 34
-
-
Kunz, L.I.1
Lapperre, T.S.2
Snoeck-Stroband, J.B.3
-
17
-
-
70249107150
-
Efficacy of salmeterol/fluticasone propionate by GOLD stage of chronic obstructive pulmonary disease: Analysis from the randomised, placebo-controlled TORCH study
-
Jenkins CR, Jones PW, Calverley PM, et al. Efficacy of salmeterol/fluticasone propionate by GOLD stage of chronic obstructive pulmonary disease: analysis from the randomised, placebo-controlled TORCH study. Respir Res 2009; 10: 59.
-
(2009)
Respir Res
, vol.10
, pp. 59
-
-
Jenkins, C.R.1
Jones, P.W.2
Calverley, P.M.3
-
18
-
-
69949147507
-
Glucocorticoid sensitivity of lipopolysaccharide-stimulated chronic obstructive pulmonary disease alveolar macrophages
-
Armstrong J, Sargent C, Singh D. Glucocorticoid sensitivity of lipopolysaccharide-stimulated chronic obstructive pulmonary disease alveolar macrophages. Clin Exp Immunol 2009; 158: 74-83.
-
(2009)
Clin Exp Immunol
, vol.158
, pp. 74-83
-
-
Armstrong, J.1
Sargent, C.2
Singh, D.3
-
19
-
-
80052165379
-
Synergistic effects of p38 mitogen-activated protein kinase inhibition with a corticosteroid in alveolar macrophages from patients with chronic obstructive pulmonary disease
-
Armstrong J, Harbron C, Lea S, et al. Synergistic effects of p38 mitogen-activated protein kinase inhibition with a corticosteroid in alveolar macrophages from patients with chronic obstructive pulmonary disease. J Pharmacol Exp Ther 2011; 338: 732-740.
-
(2011)
J Pharmacol Exp Ther
, vol.338
, pp. 732-740
-
-
Armstrong, J.1
Harbron, C.2
Lea, S.3
-
20
-
-
84863643134
-
IFN-c synergistically enhances LPS signalling in alveolar macrophages from COPD patients and controls by corticosteroid-resistant STAT1 activation
-
Southworth T, Metryka A, Lea S, et al. IFN-c synergistically enhances LPS signalling in alveolar macrophages from COPD patients and controls by corticosteroid-resistant STAT1 activation. Br J Pharmacol 2012; 166: 2070-2083.
-
(2012)
Br J Pharmacol
, vol.166
, pp. 2070-2083
-
-
Southworth, T.1
Metryka, A.2
Lea, S.3
-
21
-
-
77951621270
-
Treatment with a peroxisomal proliferator activated receptor c agonist has a modest effect in the allergen challenge model in asthma: A randomised controlled trial
-
Richards DB, Bareille P, Lindo EL, et al. Treatment with a peroxisomal proliferator activated receptor c agonist has a modest effect in the allergen challenge model in asthma: a randomised controlled trial. RespirMed 2009; 104: 668-674.
-
(2009)
RespirMed
, vol.104
, pp. 668-674
-
-
Richards, D.B.1
Bareille, P.2
Lindo, E.L.3
-
22
-
-
67650617728
-
Bronchodilatory effect of the PPAR-c agonist rosiglitazone in smokers with asthma
-
Spears M, Donnelly I, Jolly L, et al. Bronchodilatory effect of the PPAR-c agonist rosiglitazone in smokers with asthma. Clin Pharmacol Ther 2009; 86: 49-53.
-
(2009)
Clin Pharmacol Ther
, vol.86
, pp. 49-53
-
-
Spears, M.1
Donnelly, I.2
Jolly, L.3
-
23
-
-
34250212715
-
Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
-
Nissen SE, Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 2007; 356: 2457-2471.
-
(2007)
N Engl J Med
, vol.356
, pp. 2457-2471
-
-
Nissen, S.E.1
Wolski, K.2
-
24
-
-
34147214922
-
-
Global Initiative for Chronic Obstructive Lung Disease, Date last accessed: September 2, 2012. Date last updated: February 2013
-
Global Initiative for Chronic Obstructive Lung Disease. Global Strategy for the Diagnosis, Management and Prevention of COPD. 2013. www.goldcopd.org/ guidelines-global-strategy-for-diagnosis-management.html Date last accessed: September 2, 2012. Date last updated: February 2013.
-
(2013)
Global Strategy for the Diagnosis, Management and Prevention of COPD
-
-
-
25
-
-
35648972677
-
Selective modulation of promoter recruitment and transcriptional activity of PPARc
-
Sears DD, Hsiao A, Ofrecio JM, et al. Selective modulation of promoter recruitment and transcriptional activity of PPARc. Biochem Biophys Res Commun 2007; 364: 515-521.
-
(2007)
Biochem Biophys Res Commun
, vol.364
, pp. 515-521
-
-
Sears, D.D.1
Hsiao, A.2
Ofrecio, J.M.3
-
26
-
-
67651166868
-
Pioglitazone inhibits Toll-like receptor expression and activity in human monocytes and db/db mice
-
Dasu MR, Park S, Devaraj S, et al. Pioglitazone inhibits Toll-like receptor expression and activity in human monocytes and db/db mice. Endocrinology 2009; 150: 3457-3464.
-
(2009)
Endocrinology
, vol.150
, pp. 3457-3464
-
-
Dasu, M.R.1
Park, S.2
Devaraj, S.3
-
27
-
-
23844470219
-
Pharmacological profile of a novel, non-TZD PPARc agonist
-
Chen X, Osborne MC, Rybczynski PJ, et al. Pharmacological profile of a novel, non-TZD PPARc agonist. Diabetes Obes Metab 2005; 7: 536-546.
-
(2005)
Diabetes Obes Metab
, vol.7
, pp. 536-546
-
-
Chen, X.1
Osborne, M.C.2
Rybczynski, P.J.3
-
28
-
-
69249083645
-
Increased T-regulatory cells within lymphocyte follicles in moderate COPD
-
Plumb J, Smyth LJ, Adams HR, et al. Increased T-regulatory cells within lymphocyte follicles in moderate COPD. Eur Respir J 2009; 34: 89-94.
-
(2009)
Eur Respir J
, vol.34
, pp. 89-94
-
-
Plumb, J.1
Smyth, L.J.2
Adams, H.R.3
-
29
-
-
31844436294
-
Stability of housekeeping genes in alveolar macrophages from COPD patients
-
Ishii T, Wallace AM, Zhang X, et al. Stability of housekeeping genes in alveolar macrophages from COPD patients. Eur Respir J 2006; 27: 300-306.
-
(2006)
Eur Respir J
, vol.27
, pp. 300-306
-
-
Ishii, T.1
Wallace, A.M.2
Zhang, X.3
-
30
-
-
51649104671
-
Advances in neutrophil biology: Clinical implications
-
Cowburn AS, Condliffe AM, Farahi N, et al. Advances in neutrophil biology: clinical implications. Chest 2008; 134: 606-612.
-
(2008)
Chest
, vol.134
, pp. 606-612
-
-
Cowburn, A.S.1
Condliffe, A.M.2
Farahi, N.3
-
31
-
-
78149454651
-
Treating viral exacerbations of chronic obstructive pulmonary disease: Insights from a mouse model of cigarette smoke and H1N1 influenza infection
-
Bauer CM, Zavitz CC, Botelho FM, et al. Treating viral exacerbations of chronic obstructive pulmonary disease: insights from a mouse model of cigarette smoke and H1N1 influenza infection. PLoS One 2010; 5: e13251.
-
(2010)
PLoS One
, vol.5
-
-
Bauer, C.M.1
Zavitz, C.C.2
Botelho, F.M.3
-
33
-
-
84874986674
-
Cardiovascular disease in COPD: Mechanisms
-
Maclay JD, MacNee W. Cardiovascular disease in COPD: mechanisms. Chest 2013; 143: 798-807.
-
(2013)
Chest
, vol.143
, pp. 798-807
-
-
Maclay, J.D.1
Macnee, W.2
-
34
-
-
78649388701
-
STAT6 transcription factor is a facilitator of the nuclear receptor PPARcregulated gene expression in macrophages and dendritic cells
-
Szanto A, Balint BL, Nagy ZS, et al. STAT6 transcription factor is a facilitator of the nuclear receptor PPARcregulated gene expression in macrophages and dendritic cells. Immunity 2010; 33: 699-712.
-
(2010)
Immunity
, vol.33
, pp. 699-712
-
-
Szanto, A.1
Balint, B.L.2
Nagy, Z.S.3
-
35
-
-
1642493927
-
Antiinflammatory roles of peroxisome proliferator-activated receptor c in human alveolar macrophages
-
Asada K, Sasaki S, Suda T, et al. Antiinflammatory roles of peroxisome proliferator-activated receptor c in human alveolar macrophages. Am J Respir Crit Care Med 2004; 169: 195-200.
-
(2004)
Am J Respir Crit Care Med
, vol.169
, pp. 195-200
-
-
Asada, K.1
Sasaki, S.2
Suda, T.3
-
36
-
-
0034614270
-
Activation of PPARa or c reduces secretion of matrix metalloproteinase 9 but not interleukin 8 from human monocytic THP-1 cells
-
Shu H, Wong B, Zhou G, et al. Activation of PPARa or c reduces secretion of matrix metalloproteinase 9 but not interleukin 8 from human monocytic THP-1 cells. Biochem Biophys Res Commun 2000; 267: 345-349.
-
(2000)
Biochem Biophys Res Commun
, vol.267
, pp. 345-349
-
-
Shu, H.1
Wong, B.2
Zhou, G.3
-
37
-
-
24144465889
-
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors
-
Ogawa S, Lozach J, Benner C, et al. Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell 2005; 122: 707-721.
-
(2005)
Cell
, vol.122
, pp. 707-721
-
-
Ogawa, S.1
Lozach, J.2
Benner, C.3
-
38
-
-
0034583170
-
Regulation of macrophage gene expression by the peroxisome proliferator-activated receptor-c
-
Ricote M, Welch JS, Glass CK. Regulation of macrophage gene expression by the peroxisome proliferator-activated receptor-c. Horm Res 2000; 54: 275-280.
-
(2000)
Horm Res
, vol.54
, pp. 275-280
-
-
Ricote, M.1
Welch, J.S.2
Glass, C.K.3
-
39
-
-
0032737858
-
The peroxisome proliferator-activated receptorc (PPARc) as a regulator of monocyte/macrophage function
-
Ricote M, Huang JT, Welch JS, et al. The peroxisome proliferator- activated receptorc (PPARc) as a regulator of monocyte/macrophage function. J Leukoc Biol 1999; 66: 733-739.
-
(1999)
J Leukoc Biol
, vol.66
, pp. 733-739
-
-
Ricote, M.1
Huang, J.T.2
Welch, J.S.3
-
40
-
-
10744232382
-
Interleukin-13 and -4 expression in the central airways of smokers with chronic bronchitis
-
Miotto D, Ruggieri MP, Boschetto P, et al. Interleukin-13 and -4 expression in the central airways of smokers with chronic bronchitis. Eur Respir J 2003; 22: 602-608.
-
(2003)
Eur Respir J
, vol.22
, pp. 602-608
-
-
Miotto, D.1
Ruggieri, M.P.2
Boschetto, P.3
-
41
-
-
73249148029
-
The effects of dexamethasone on cigarette smoke induced gene expression changes in COPD macrophages
-
Kent LM, Fox SM, Farrow SN, et al. The effects of dexamethasone on cigarette smoke induced gene expression changes in COPD macrophages. Int Immunopharmacol 2010; 10: 57-64.
-
(2010)
Int Immunopharmacol
, vol.10
, pp. 57-64
-
-
Kent, L.M.1
Fox, S.M.2
Farrow, S.N.3
-
42
-
-
0037975679
-
Decreased haem oxygenase-1 and increased inducible nitric oxide synthase in the lung of severe COPD patients
-
Maestrelli P, Páska C, Saetta M, et al. Decreased haem oxygenase-1 and increased inducible nitric oxide synthase in the lung of severe COPD patients. Eur Respir J 2003; 21: 971-976.
-
(2003)
Eur Respir J
, vol.21
, pp. 971-976
-
-
Maestrelli, P.1
Páska, C.2
Saetta, M.3
-
43
-
-
0026453281
-
Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis
-
Savill J, Hogg N, Ren Y, et al. Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis. J Clin Invest 1992; 90: 1513-1522.
-
(1992)
J Clin Invest
, vol.90
, pp. 1513-1522
-
-
Savill, J.1
Hogg, N.2
Ren, Y.3
-
44
-
-
0032400966
-
CD36 is required for phagocytosis of apoptotic cells by human macrophages that use either a phosphatidylserine receptor or the vitronectin receptor (avb3)
-
Fadok VA, Warner ML, Bratton DL, et al. CD36 is required for phagocytosis of apoptotic cells by human macrophages that use either a phosphatidylserine receptor or the vitronectin receptor (avb3). J Immunol 1998; 161: 6250-6257.
-
(1998)
J Immunol
, vol.161
, pp. 6250-6257
-
-
Fadok, V.A.1
Warner, M.L.2
Bratton, D.L.3
|