Polyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Choi, Soo Ho ^a   Yin, Huiyong ^b,c,d   Ravandi, Amir ^e   Armando, Aaron ^f   Dumlao, Darren ^f   Kim, Jungsu ^a   Almazan, Felicidad ^a   Taylor, Angela M ^g   McNamara, Coleen A ^g   Tsimikas, Sotirios ^a   Dennis, Edward A ^f   Witztum, Joseph L ^a   Miller, Yury I ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^c BEIJING HOSPITAL   (China)

^d SHANGHAITECH UNIVERSITY   (China)

^e UNIVERSITY OF MANITOBA   (Canada)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CHOLESTEROL; CHOLESTEROL, LDL; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPROTEINS, LDL; LYMPHOCYTE ANTIGEN 96; MACROPHAGES; MAP KINASE KINASE 4; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; OXIDATION-REDUCTION; PLAQUE, ATHEROSCLEROTIC; PRIMARY CELL CULTURE; PROTEIN MULTIMERIZATION; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84893456202     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0083145     Document Type: Article

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