Design and synthesis of a stable oxidized phospholipid mimic with specific binding recognition for macrophage scavenger receptors

Journal of Medicinal Chemistry

Volumn 55, Issue 18, 2012, Pages 8178-8182

  Turner, William W ^a   Hartvigsen, Karsten ^b,c   Boullier, Agnes ^d   Montano, Erica N ^b   Witztum, Joseph L ^b   Vannieuwenhze, Michael S ^a  

^a INDIANA UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

13 [[2 [(CARBOXYMETHYL)AMINO] 2 OXOETHYL]CARBAMOYL] 4,10 BIS(1 HYDROXYETHYL) 18 METHYL 2,5,8,11,23 PENTAOXO 25 [(PALMITOYLOXY)METHYL] 24 OXA 3,6,9,12,18 PENTAAZAHEXACOSAN 26 YL [2 (TRIMETHYLAMMONIO)ETHYL]PHOSPHATE; CD36 ANTIGEN; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHATIDYLCHOLINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; MOLECULAR STABILITY; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN SYNTHESIS; SOLUBILITY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD36; BIOMIMETIC MATERIALS; CHEMISTRY TECHNIQUES, SYNTHETIC; DRUG DESIGN; DRUG STABILITY; HUMANS; MICE; OXIDATION-REDUCTION; PHOSPHOLIPID ETHERS; PROTEIN BINDING; SOLUBILITY; SUBSTRATE SPECIFICITY; WATER;

EID: 84866861671     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm300685s     Document Type: Article

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