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Volumn 38, Issue 7, 1997, Pages 1347-1360

Oxidation products of cholesteryl linoleate are resistant to hydrolysis in macrophages, form complexes with proteins, and are present in human atherosclerotic lesions

Author keywords

Acid cholesteryl ester hydrolase; Cholesterol oxidase; Cholesteryl ester; Filipin; Free cholesterol; Human atherosclerotic lesions; Lipid peroxidation; Low density lipoprotein; Mouse peritoneal macrophage; Neutral cholesteryl ester hydrolase; Phosphatidylcholine; Phosphatidylserine

Indexed keywords

CEROID; CHOLESTERYL LINOLEIC ACID; LIPID; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; STEROL; UNCLASSIFIED DRUG;

EID: 0030860973     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (89)

References (53)
  • 1
    • 0028289443 scopus 로고
    • A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association
    • Stary, H. C., A. B. Chandler, S. Glagov, J. R. Guyton, W. Insulls, Jr., M. E. Rosenfeld, S. A. Schaffer, C. J. Schwartz, W. D. Wagner, and R. W. Wissler. 1994. A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation. 89: 2462-2478.
    • (1994) Circulation , vol.89 , pp. 2462-2478
    • Stary, H.C.1    Chandler, A.B.2    Glagov, S.3    Guyton, J.R.4    Insulls Jr., W.5    Rosenfeld, M.E.6    Schaffer, S.A.7    Schwartz, C.J.8    Wagner, W.D.9    Wissler, R.W.10
  • 2
    • 0018120952 scopus 로고
    • Characterization of lipid-laden aortic cells from cholesterol-fed rabbits. II. Morphometric analysis of lipid-filled lysosomes and lipid droplets in aortic cell populations
    • Shio, H., N. Haley, and S. Fowler. 1978. Characterization of lipid-laden aortic cells from cholesterol-fed rabbits. II. Morphometric analysis of lipid-filled lysosomes and lipid droplets in aortic cell populations. Lab. Invest. 39: 390-397.
    • (1978) Lab. Invest. , vol.39 , pp. 390-397
    • Shio, H.1    Haley, N.2    Fowler, S.3
  • 3
    • 0021844647 scopus 로고
    • Early atherogenesis in White Carneau pigeons. Ultrastructural and cytochemical observations
    • Jerome, W. G., and J. C. Lewis. 1985. Early atherogenesis in White Carneau pigeons. Ultrastructural and cytochemical observations. Am. J. Pathol. 119: 210-222.
    • (1985) Am. J. Pathol. , vol.119 , pp. 210-222
    • Jerome, W.G.1    Lewis, J.C.2
  • 4
    • 0026748405 scopus 로고
    • The intracellular storage and turnover of apolipoprotein B of oxidized LDL in macrophages
    • Jessup, W., E. L. Mander, and R. T. Dean. 1992. The intracellular storage and turnover of apolipoprotein B of oxidized LDL in macrophages. Biochim. Biophys. Acta. 1126: 167-177.
    • (1992) Biochim. Biophys. Acta , vol.1126 , pp. 167-177
    • Jessup, W.1    Mander, E.L.2    Dean, R.T.3
  • 5
    • 0026353855 scopus 로고
    • Oxidized low density lipoprotein is resistant to cathepsins and accumulates within macrophages
    • Lougheed, M., H. Zhang, and U. P. Steinbrecher. 1991. Oxidized low density lipoprotein is resistant to cathepsins and accumulates within macrophages. J. Biol. Chem. 266: 14519-14525.
    • (1991) J. Biol. Chem. , vol.266 , pp. 14519-14525
    • Lougheed, M.1    Zhang, H.2    Steinbrecher, U.P.3
  • 6
    • 0027482391 scopus 로고
    • Aggregation as well as chemical modification of LDL during oxidation is responsible for poor processing in macrophages
    • Hoff, H. F., N. Zyromski, D. Armstrong, and J. O'Neil. 1993. Aggregation as well as chemical modification of LDL during oxidation is responsible for poor processing in macrophages. J. Lipid Res. 34: 1919-1929.
    • (1993) J. Lipid Res. , vol.34 , pp. 1919-1929
    • Hoff, H.F.1    Zyromski, N.2    Armstrong, D.3    O'Neil, J.4
  • 7
    • 0028207078 scopus 로고
    • Apolipoprotein B of oxidized LDL accumulates in the lysosomes of macrophages
    • Mander, E. L., R. T. Dean, K. K. Stanley, and W. Jessup. 1994. Apolipoprotein B of oxidized LDL accumulates in the lysosomes of macrophages. Biochim. Biophys. Acta. 212: 80-92.
    • (1994) Biochim. Biophys. Acta , vol.212 , pp. 80-92
    • Mander, E.L.1    Dean, R.T.2    Stanley, K.K.3    Jessup, W.4
  • 8
    • 0028060607 scopus 로고
    • Inactivation of lysosomal proteases by oxidized LDL is partially responsible for its poor degradation by macrophages
    • Hoppe, G., J. O'Neil, and H. F. Hoff. 1994. Inactivation of lysosomal proteases by oxidized LDL is partially responsible for its poor degradation by macrophages. J. Clin. Invest. 94: 1506-1512.
    • (1994) J. Clin. Invest. , vol.94 , pp. 1506-1512
    • Hoppe, G.1    O'Neil, J.2    Hoff, H.F.3
  • 9
    • 0022494003 scopus 로고
    • Oxidized low density lipoprotein induces ceroid accumulation by murine peritoneal macrophages in vitro
    • Ball, R. Y., J. P. Bindman, K. L. H. Carpenter, and M. J. Mitchinson. 1986. Oxidized low density lipoprotein induces ceroid accumulation by murine peritoneal macrophages in vitro. Atherosclerosis. 60: 173-181.
    • (1986) Atherosclerosis , vol.60 , pp. 173-181
    • Ball, R.Y.1    Bindman, J.P.2    Carpenter, K.L.H.3    Mitchinson, M.J.4
  • 10
    • 0028205859 scopus 로고
    • Differing effects of probucol and vitamin E on the oxidation of lipoproteins, ceroid accumulation and protein uptake by macrophages
    • Hunt, J. V., M. A. Bottoms, S. E. Taylor, V. Lyell, and M. J. Mitchinson. 1994. Differing effects of probucol and vitamin E on the oxidation of lipoproteins, ceroid accumulation and protein uptake by macrophages. Free Radical Res. 20: 189-201.
    • (1994) Free Radical Res. , vol.20 , pp. 189-201
    • Hunt, J.V.1    Bottoms, M.A.2    Taylor, S.E.3    Lyell, V.4    Mitchinson, M.J.5
  • 11
    • 0023630825 scopus 로고
    • What is the significance of ceroid in human atherosclerosis?
    • Ball, R. Y., K. L. H. Carpenter, and M. J. Mitchinson. 1987. What is the significance of ceroid in human atherosclerosis? Arch. Pathol. Lab. Med. 111: 1134-1140.
    • (1987) Arch. Pathol. Lab. Med. , vol.111 , pp. 1134-1140
    • Ball, R.Y.1    Carpenter, K.L.H.2    Mitchinson, M.J.3
  • 12
    • 0025032215 scopus 로고
    • Lipofuscin-like substances accumulate rapidly in brain, retina and internal organs with cysteine protease inhibition
    • E. A. Porta, editor. Plenum Press, New York, N.Y.
    • Ivy, G. O., S. Kanai, M. Ohta, G. Smith, Y. Sato, M. Kobayashi, and K. Kitani. 1990. Lipofuscin-like substances accumulate rapidly in brain, retina and internal organs with cysteine protease inhibition. In Lipofuscin and Ceroid Pigments. E. A. Porta, editor. Plenum Press, New York, N.Y. 31-47.
    • (1990) Lipofuscin and Ceroid Pigments , pp. 31-47
    • Ivy, G.O.1    Kanai, S.2    Ohta, M.3    Smith, G.4    Sato, Y.5    Kobayashi, M.6    Kitani, K.7
  • 13
    • 0026754449 scopus 로고
    • Preparation, chromatography, and mass spectrometry of cholesteryl ester and glycerolipid-bound aldehydes
    • Kamido, H., A. Kuksis, L. Marai, J. J. Myher, and H. Peng. 1992. Preparation, chromatography, and mass spectrometry of cholesteryl ester and glycerolipid-bound aldehydes. Lipids. 27: 645-650.
    • (1992) Lipids , vol.27 , pp. 645-650
    • Kamido, H.1    Kuksis, A.2    Marai, L.3    Myher, J.J.4    Peng, H.5
  • 14
    • 0014379086 scopus 로고
    • Practical method for plasma lipoprotein analysis
    • Hatch, F. T., and R. S. Lees. 1968. Practical method for plasma lipoprotein analysis. Adv. Lipids Res. 6: 2-63.
    • (1968) Adv. Lipids Res. , vol.6 , pp. 2-63
    • Hatch, F.T.1    Lees, R.S.2
  • 15
    • 0023252320 scopus 로고
    • Cholesteryl ester transfer activity in plasma measured by using solid-phase-bound high-density lipoprotein
    • Sparks, D. L., J. Frohlich, P. Cullis, and P. H. Pritchard. 1987. Cholesteryl ester transfer activity in plasma measured by using solid-phase-bound high-density lipoprotein. Clin. Chem. 33: 390-393.
    • (1987) Clin. Chem. , vol.33 , pp. 390-393
    • Sparks, D.L.1    Frohlich, J.2    Cullis, P.3    Pritchard, P.H.4
  • 16
    • 0009627006 scopus 로고
    • Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition
    • Goldstein, J. L., Y. K. Ho, S. K. Basu, and M. S. Brown. 1979. Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition. Proc. Natl. Acad. Sci. USA. 76: 333-337.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 333-337
    • Goldstein, J.L.1    Ho, Y.K.2    Basu, S.K.3    Brown, M.S.4
  • 17
    • 0024465165 scopus 로고
    • Recognition of oxidized low density lipoprotein by the scavenger receptor of macrophages results from derivatization of apolipoprotein B byproducts of fatty acid peroxidation
    • Steinbrecher, U. P., M. Lougheed, W-C. Kwan, and M. Dirks. 1989. Recognition of oxidized low density lipoprotein by the scavenger receptor of macrophages results from derivatization of apolipoprotein B byproducts of fatty acid peroxidation. J. Biol. Chem. 264: 15216-15223.
    • (1989) J. Biol. Chem. , vol.264 , pp. 15216-15223
    • Steinbrecher, U.P.1    Lougheed, M.2    Kwan, W.-C.3    Dirks, M.4
  • 18
    • 0021320894 scopus 로고
    • Selective inhibition of acyl-coenzyme A: Cholesterol acyltransferase by compound 58-035
    • Ross, A. C., K. L. Go, J. G. Heider, and G. H. Rothblat. 1984. Selective inhibition of acyl-coenzyme A: cholesterol acyltransferase by compound 58-035. J. Biol. Chem. 259: 815-819.
    • (1984) J. Biol. Chem. , vol.259 , pp. 815-819
    • Ross, A.C.1    Go, K.L.2    Heider, J.G.3    Rothblat, G.H.4
  • 19
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh, E. J., and W. J. Dyer. 1959. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37: 911-917.
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.J.1    Dyer, W.J.2
  • 20
    • 0018128226 scopus 로고
    • Lipid extraction of tissues with low-toxicity solvent
    • Hara, A., and N. S. Radin. 1978. Lipid extraction of tissues with low-toxicity solvent. Anal. Biochem. 90: 420-426.
    • (1978) Anal. Biochem. , vol.90 , pp. 420-426
    • Hara, A.1    Radin, N.S.2
  • 21
    • 0021076445 scopus 로고
    • Analysis of the distribution of cholesterol in the intact cell
    • Lange, Y., and B. V. Ramos. 1983. Analysis of the distribution of cholesterol in the intact cell. J. Biol. Chem. 258: 15130-15134.
    • (1983) J. Biol. Chem. , vol.258 , pp. 15130-15134
    • Lange, Y.1    Ramos, B.V.2
  • 22
    • 0029164660 scopus 로고
    • Lipid ester-bound aldehydes among copper-catalyzed peroxidation products of human plasma lipoproteins
    • Kamido, H., A. Kuksis, L. Marai, and J. J. Myher. 1995. Lipid ester-bound aldehydes among copper-catalyzed peroxidation products of human plasma lipoproteins. J. Lipid Res. 36: 1876-1886.
    • (1995) J. Lipid Res. , vol.36 , pp. 1876-1886
    • Kamido, H.1    Kuksis, A.2    Marai, L.3    Myher, J.J.4
  • 23
    • 0027481093 scopus 로고
    • Identification of core aldehydes among in vitro peroxidation products of cholesteryl esters
    • Kamido, H., A. Kuksis, L. Marai, and J. J. Myher. 1993. Identification of core aldehydes among in vitro peroxidation products of cholesteryl esters. Lipids. 28: 331-336.
    • (1993) Lipids , vol.28 , pp. 331-336
    • Kamido, H.1    Kuksis, A.2    Marai, L.3    Myher, J.J.4
  • 24
    • 0028808781 scopus 로고
    • Determination of lipid ester ozonides and core aldehydes by high-performance liquid chromatography with on-line mass spectrometry
    • Ravandi, A., A. Kuksis, J. J. Myher, L. Marai. 1995. Determination of lipid ester ozonides and core aldehydes by high-performance liquid chromatography with on-line mass spectrometry. J. Biochem. Biophys. Methods. 30: 271-285.
    • (1995) J. Biochem. Biophys. Methods , vol.30 , pp. 271-285
    • Ravandi, A.1    Kuksis, A.2    Myher, J.J.3    Marai, L.4
  • 26
    • 0030586275 scopus 로고    scopus 로고
    • Filipin as a fluorescent probe of lipoprotein-derived oxysterols on thin-layer chromatograms
    • Smejkal, G., G. Hoppe, and H. F. Hoff. 1996. Filipin as a fluorescent probe of lipoprotein-derived oxysterols on thin-layer chromatograms. Anal. Biochem. 239: 115-117.
    • (1996) Anal. Biochem. , vol.239 , pp. 115-117
    • Smejkal, G.1    Hoppe, G.2    Hoff, H.F.3
  • 27
    • 0021359270 scopus 로고
    • Filipin-positive, oil red O-negative particles in atherosclerotic lesions induced by cholesterol feeding
    • Kruth, H. S. 1983. Filipin-positive, oil red O-negative particles in atherosclerotic lesions induced by cholesterol feeding. Lab. Invest. 50: 87-93.
    • (1983) Lab. Invest. , vol.50 , pp. 87-93
    • Kruth, H.S.1
  • 28
    • 0025219143 scopus 로고
    • Scavenger receptor-mediated uptake and metabolism of lipid vesicles containing acidic phospholipids by mouse peritoneal macrophages
    • Nishikawa, K., H. Arai, and K. Inoue. 1990. Scavenger receptor-mediated uptake and metabolism of lipid vesicles containing acidic phospholipids by mouse peritoneal macrophages. J. Biol. Chem. 265: 5226-5231.
    • (1990) J. Biol. Chem. , vol.265 , pp. 5226-5231
    • Nishikawa, K.1    Arai, H.2    Inoue, K.3
  • 29
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer, H., R. J. Schaur, and H. Zollner. 1991. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radical Biol. Med. 11: 81-128.
    • (1991) Free Radical Biol. Med. , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 30
    • 0027480753 scopus 로고
    • Covalent attachment of 4-hydroxynonenal to glyceraldehyde-3-phosphate dehydrogenase. A possible involvement of intra- and intermolecular cross-linking reaction
    • Uchida, K., and E. R. Stadtman. 1993. Covalent attachment of 4-hydroxynonenal to glyceraldehyde-3-phosphate dehydrogenase. A possible involvement of intra- and intermolecular cross-linking reaction. J. Biol. Chem. 268: 6388-6693.
    • (1993) J. Biol. Chem. , vol.268 , pp. 6388-6693
    • Uchida, K.1    Stadtman, E.R.2
  • 31
    • 0026167787 scopus 로고
    • Investigation of collisional-activation decomposition process and spectra in the transport region of an electrospray single quadruple mass spectrometer
    • Voyksner, R. D., and T. Pack. 1991. Investigation of collisional-activation decomposition process and spectra in the transport region of an electrospray single quadruple mass spectrometer. Mass Spectrom. 5: 263-268.
    • (1991) Mass Spectrom. , vol.5 , pp. 263-268
    • Voyksner, R.D.1    Pack, T.2
  • 32
    • 0343178270 scopus 로고    scopus 로고
    • Identification of lipid ester core aldehydes and hydroperoxides in human atherosclerotic lesions
    • Kamido, H., K. Nonaka, A. Kuksis, L. Marai, and A. Ravandi. 1996. Identification of lipid ester core aldehydes and hydroperoxides in human atherosclerotic lesions. Circulation. 94(Suppl): I-707.
    • (1996) Circulation , vol.94 , Issue.SUPPL.
    • Kamido, H.1    Nonaka, K.2    Kuksis, A.3    Marai, L.4    Ravandi, A.5
  • 33
    • 0029872744 scopus 로고    scopus 로고
    • Free and esterified oxysterol: Formation during copper-oxidation of low density lipoprotein and uptake by macrophages
    • Brown, A. J., R. T. Dean, and W. Jessup. 1996. Free and esterified oxysterol: formation during copper-oxidation of low density lipoprotein and uptake by macrophages. J. Lipid Res. 37: 320-335.
    • (1996) J. Lipid Res. , vol.37 , pp. 320-335
    • Brown, A.J.1    Dean, R.T.2    Jessup, W.3
  • 35
    • 0027317432 scopus 로고
    • A method for defining the stages of low-density lipoprotein oxidation by the separation of cholesterol- and cholesteryl ester-oxidation products using HPLC
    • Kritharides, L., W. Jessup, J. Gifford, and R. T. Dean. 1993. A method for defining the stages of low-density lipoprotein oxidation by the separation of cholesterol- and cholesteryl ester-oxidation products using HPLC. Anal. Biochem. 213: 79-89.
    • (1993) Anal. Biochem. , vol.213 , pp. 79-89
    • Kritharides, L.1    Jessup, W.2    Gifford, J.3    Dean, R.T.4
  • 36
    • 0028855309 scopus 로고
    • Monitoring of lipoprotein oxidation by gas chromatographic analysis of hydroxy fatty acids
    • Nikkari, T., U. Malo-Ranta, T. Hiltunen, O. Jaakkola, S. Ylä-Herttuala. 1995. Monitoring of lipoprotein oxidation by gas chromatographic analysis of hydroxy fatty acids. J. Lipid Res. 36: 200-207.
    • (1995) J. Lipid Res. , vol.36 , pp. 200-207
    • Nikkari, T.1    Malo-Ranta, U.2    Hiltunen, T.3    Jaakkola, O.4    Ylä-Herttuala, S.5
  • 37
    • 0024468045 scopus 로고
    • Methods for determination of aldehydic lipid peroxidation products
    • Esterbauer, H., and H. Zollner. 1989. Methods for determination of aldehydic lipid peroxidation products. Free Rad. Biol. Med. 7: 197-203.
    • (1989) Free Rad. Biol. Med. , vol.7 , pp. 197-203
    • Esterbauer, H.1    Zollner, H.2
  • 38
    • 0026721424 scopus 로고
    • Identification of cholesterol-bound aldehydes in copper-oxidized low density lipoprotein
    • Kamido, H., A. Kuksis, L. Marai, and J. J. Myher. 1992. Identification of cholesterol-bound aldehydes in copper-oxidized low density lipoprotein. FEBS Lett. 304: 269-272.
    • (1992) FEBS Lett. , vol.304 , pp. 269-272
    • Kamido, H.1    Kuksis, A.2    Marai, L.3    Myher, J.J.4
  • 39
    • 0030462113 scopus 로고    scopus 로고
    • Oxidized phosphatidylcholines that modify proteins. Analysis by monoclonal antibody against oxidized low density lipoprotein
    • Itabe, H., H. Yamamoto, M. Suzuki, Y. Kawai, Y. Nakagawa, A. Suzuki, T. Imanaka, and T. Takano. 1996. Oxidized phosphatidylcholines that modify proteins. Analysis by monoclonal antibody against oxidized low density lipoprotein. J. Biol. Chem. 271: 33208-33217.
    • (1996) J. Biol. Chem. , vol.271 , pp. 33208-33217
    • Itabe, H.1    Yamamoto, H.2    Suzuki, M.3    Kawai, Y.4    Nakagawa, Y.5    Suzuki, A.6    Imanaka, T.7    Takano, T.8
  • 40
    • 0015036331 scopus 로고
    • Lipid of human atheroma. Part 4. Characterization of a new group of polar sterol esters from human atherosclerotic plaques
    • Brooks, C. J. W., G. Steel, J. D. Gilbert, and W. A. Harland. 1971. Lipid of human atheroma. Part 4. Characterization of a new group of polar sterol esters from human atherosclerotic plaques. Atherosclerosis. 13: 223-237.
    • (1971) Atherosclerosis , vol.13 , pp. 223-237
    • Brooks, C.J.W.1    Steel, G.2    Gilbert, J.D.3    Harland, W.A.4
  • 41
    • 0028321941 scopus 로고
    • A monoclonal antibody against oxidized lipoprotein recognizes foam cells in atherosclerotic lesions. Complex formation of oxidized phosphatidylcholines and polypeptides
    • Itabe, H., E. Takeshima, H. Iwasaki, J. Kimura, Y. Yoshida, T. Imanaka, and T. Takano. 1994. A monoclonal antibody against oxidized lipoprotein recognizes foam cells in atherosclerotic lesions. Complex formation of oxidized phosphatidylcholines and polypeptides. J. Biol. Chem. 269: 15274-15279.
    • (1994) J. Biol. Chem. , vol.269 , pp. 15274-15279
    • Itabe, H.1    Takeshima, E.2    Iwasaki, H.3    Kimura, J.4    Yoshida, Y.5    Imanaka, T.6    Takano, T.7
  • 42
    • 0023153340 scopus 로고
    • Acyl-chain specificity and properties of cholesterol esterases from normal and Wolman lymphoid cell lines
    • Négre, A., R. Salvayre, P. Rogalle, Q. Q. Dang, and L. Douste-Blazy. 1987. Acyl-chain specificity and properties of cholesterol esterases from normal and Wolman lymphoid cell lines. Biochim. Biophys. Acta. 918: 76-82.
    • (1987) Biochim. Biophys. Acta , vol.918 , pp. 76-82
    • Négre, A.1    Salvayre, R.2    Rogalle, P.3    Dang, Q.Q.4    Douste-Blazy, L.5
  • 43
    • 0028273337 scopus 로고
    • Inhibitory effect of lipid hydroperoxide on cholesteryl esterases
    • Maehira, F. 1994. Inhibitory effect of lipid hydroperoxide on cholesteryl esterases. Biochem. Mol. Biol. Int. 32: 221-231.
    • (1994) Biochem. Mol. Biol. Int. , vol.32 , pp. 221-231
    • Maehira, F.1
  • 44
    • 0024603672 scopus 로고
    • Effects of cholesterol oxidation derivatives on cholesterol esterifying and cholesteryl ester hydrolytic enzyme activity of cultured rabbit aortic smooth muscle cells
    • Morin, R. J., and S-K. Peng. 1989. Effects of cholesterol oxidation derivatives on cholesterol esterifying and cholesteryl ester hydrolytic enzyme activity of cultured rabbit aortic smooth muscle cells. Lipids. 24: 217-220.
    • (1989) Lipids , vol.24 , pp. 217-220
    • Morin, R.J.1    Peng, S.-K.2
  • 45
    • 0028362152 scopus 로고
    • Oxidized low density lipoprotein leads to macrophage accumulation of unesterified cholesterol as a result of lysosomal trapping of the lipoprotein hydrolyzed cholesteryl ester
    • Maor, I., and M. Aviram. 1994. Oxidized low density lipoprotein leads to macrophage accumulation of unesterified cholesterol as a result of lysosomal trapping of the lipoprotein hydrolyzed cholesteryl ester. J. Lipid Res. 35: 803-819.
    • (1994) J. Lipid Res. , vol.35 , pp. 803-819
    • Maor, I.1    Aviram, M.2
  • 46
    • 0029164953 scopus 로고
    • Apolipoprotein B-bound lipids as a marker for evaluation of low density lipoprotein oxidation in vivo
    • Tertov, V. V., V. V. Kaplun, S. N. Dvoryantsev, and A. N. Orekhov. 1995. Apolipoprotein B-bound lipids as a marker for evaluation of low density lipoprotein oxidation in vivo. Biochem. Biophys. Res. Commun. 214: 608-613.
    • (1995) Biochem. Biophys. Res. Commun. , vol.214 , pp. 608-613
    • Tertov, V.V.1    Kaplun, V.V.2    Dvoryantsev, S.N.3    Orekhov, A.N.4
  • 47
    • 0028175960 scopus 로고
    • Generation of α-hydroxyaldehydic compounds in the course of lipid peroxidation
    • Loidl-Stahlhofen, A., K. Hannemann, and G. Spiteller. 1994. Generation of α-hydroxyaldehydic compounds in the course of lipid peroxidation. Biochim. Biophys. Acta. 1213: 140-148.
    • (1994) Biochim. Biophys. Acta , vol.1213 , pp. 140-148
    • Loidl-Stahlhofen, A.1    Hannemann, K.2    Spiteller, G.3
  • 48
    • 0030976980 scopus 로고    scopus 로고
    • Inactivation of cathepsin B by oxidized LDL involves complex formation induced by binding of putative reactive sites exposed at low pH to thiols on the enzyme
    • In press
    • O'Neil, J., G. Hoppe, L. M. Sayre, and H. F. Hoff. 1997. Inactivation of cathepsin B by oxidized LDL involves complex formation induced by binding of putative reactive sites exposed at low pH to thiols on the enzyme. Free Radical Biol. Med. 23: In press.
    • (1997) Free Radical Biol. Med. , vol.23
    • O'Neil, J.1    Hoppe, G.2    Sayre, L.M.3    Hoff, H.F.4
  • 49
    • 0028134883 scopus 로고
    • 7β-Hydroperoxycholest-5-en-3β-ol, a component of human atherosclerotic lesions, is the primary cytotoxin of oxidized human low density lipoprotein
    • Chisolm, G. M., G. Ma, K. C. Irwin, L. L. Martin, K. G. Gunderson, L. F. Linberg, D. W. Morel, and P. E. DiCorleto. 1994. 7β-Hydroperoxycholest-5-en-3β-ol, a component of human atherosclerotic lesions, is the primary cytotoxin of oxidized human low density lipoprotein. Proc. Natl. Acad. Sci. USA. 91: 11452-11456.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11452-11456
    • Chisolm, G.M.1    Ma, G.2    Irwin, K.C.3    Martin, L.L.4    Gunderson, K.G.5    Linberg, L.F.6    Morel, D.W.7    DiCorleto, P.E.8
  • 50
    • 0025315653 scopus 로고
    • Focal toxicity of oxysterols in vascular smooth muscle cell culture. A model of the atherosclerotic core region
    • Guyton, J. R., B. L. Black, and C. L. Seidel. 1990. Focal toxicity of oxysterols in vascular smooth muscle cell culture. A model of the atherosclerotic core region. Am. J. Pathol. 137: 425-434.
    • (1990) Am. J. Pathol. , vol.137 , pp. 425-434
    • Guyton, J.R.1    Black, B.L.2    Seidel, C.L.3
  • 51
    • 0023198480 scopus 로고
    • Autooxidation of human low density lipoprotein: Loss of polyunsaturated fatty acids and vitamin E and generation of aldehydes
    • Esterbauer, H., G. Jürgens, O. Quehenberger, and E. Koller. 1987. Autooxidation of human low density lipoprotein: loss of polyunsaturated fatty acids and vitamin E and generation of aldehydes. J. Lipid Res. 28: 495-509.
    • (1987) J. Lipid Res. , vol.28 , pp. 495-509
    • Esterbauer, H.1    Jürgens, G.2    Quehenberger, O.3    Koller, E.4
  • 52
    • 0025353845 scopus 로고
    • Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits
    • Rosenfeld, M. E., W. Palinski, S. Ylä-Herttuala, S. Butler, and J. L. Witztum. 1990. Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits. Arteriosclerosis. 10: 336-349.
    • (1990) Arteriosclerosis , vol.10 , pp. 336-349
    • Rosenfeld, M.E.1    Palinski, W.2    Ylä-Herttuala, S.3    Butler, S.4    Witztum, J.L.5
  • 53
    • 0028198105 scopus 로고
    • ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis: Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehydelysine in serum
    • Palinski, W., V. A. Ord, A. S. Plump, J. L. Breslow, D. Steinberg, and J. L. Witztum. 1994. ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis: demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehydelysine in serum. Arterioscler. Thromb. 14: 605-616.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 605-616
    • Palinski, W.1    Ord, V.A.2    Plump, A.S.3    Breslow, J.L.4    Steinberg, D.5    Witztum, J.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.