-
1
-
-
0037229942
-
Role of P-glycoprotein in pharmacokinetics: Clinical implications
-
Lin JH, Yamazaki M. Role of P-glycoprotein in pharmacokinetics:clinical implications. Clin Pharmacokinet. 2003;42(1):59-98
-
(2003)
Clin Pharmacokinet
, vol.42
, Issue.1
, pp. 59-98
-
-
Lin, J.H.1
Yamazaki, M.2
-
3
-
-
71949106600
-
The drug transporter-metabolism alliance: Uncovering and defining the interplay
-
Benet LZ. The drug transporter-metabolism alliance: uncovering and defining the interplay. Mol Pharm. 2009;6(6):1631-1643
-
(2009)
Mol Pharm
, vol.6
, Issue.6
, pp. 1631-1643
-
-
Benet, L.Z.1
-
4
-
-
24344439264
-
Transporters and drug therapy: Implications for drug disposition and disease
-
Ho RH, Kim RB. Transporters and drug therapy: implications for drug disposition and disease. Clin Pharmacol Ther. 2005;78 (3):260-277
-
(2005)
Clin Pharmacol Ther
, vol.78
, Issue.3
, pp. 260-277
-
-
Ho, R.H.1
Kim, R.B.2
-
5
-
-
78649661850
-
Importance of P-glycoprotein for drug-drug interactions
-
In: FrpmmMF and Kim RB (eds.),Handbook of Experimental Pharmacology. Springer-Verlag, Berlin
-
Glasser H. Importance of P-glycoprotein for drug-drug interactions. In: FrpmmMF and Kim RB (eds.), Drug Transporters, Handbook of Experimental Pharmacology. Springer-Verlag, Berlin. 2011. 285- 297
-
(2011)
Drug Transporters
, pp. 285-297
-
-
Glasser, H.1
-
6
-
-
84893338013
-
Center for Drug Evaluation and Research US FDA. Draft Guidance for industry
-
Feb 2012 [cited Feb 12, 2012]; Available from URL [Online]
-
Center for Drug Evaluation and Research US FDA. Draft Guidance for industry: drug interaction studies-study design, data analysis, and implications for dosing and labeling. Feb 2012 [cited Feb 12,2012]; Available from URL: http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/ Guidances/UCM292362.pdf [Online
-
(2012)
Drug Interaction Studies-study Design, Data Analysis, and Implications for Dosing and Labeling
-
-
-
7
-
-
23044491475
-
Meta-analysis of the influence of MDR1 C3435T polymorphism on digoxin pharmacokinetics and MDR1gene expression
-
Chowbay B, Li H, David M, Cheung YB, Lee EJ. Meta-analysis of the influence of MDR1 C3435T polymorphism on digoxin pharmacokinetics and MDR1gene expression. Br J Clin Pharmacol. 2005;60(2):159-171
-
(2005)
Br J Clin Pharmacol
, vol.60
, Issue.2
, pp. 159-171
-
-
Chowbay, B.1
Li, H.2
David, M.3
Cheung, Y.B.4
Lee, E.J.5
-
8
-
-
0036693051
-
Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein
-
Kurata Y, Ieiri I, Kimura M, et al. Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein. Clin Pharmacol Ther. 2002;72(2):209-219
-
(2002)
Clin Pharmacol Ther
, vol.72
, Issue.2
, pp. 209-219
-
-
Kurata, Y.1
Ieiri, I.2
Kimura, M.3
-
9
-
-
84879128863
-
ABCB1 single nucleotide polymorphisms (1236C>T, 2677G>T, and 3435C>T) do not affect transport activity of human P-glycoprotein
-
Dickens D, Owen A, Alfirevic A, Pirmohamed M. ABCB1 single nucleotide polymorphisms (1236C>T, 2677G>T, and 3435C>T) do not affect transport activity of human P-glycoprotein. Pharmacogenet Genomics. 2013;23(6):314-323
-
(2013)
Pharmacogenet Genomics
, vol.23
, Issue.6
, pp. 314-323
-
-
Dickens, D.1
Owen, A.2
Alfirevic, A.3
Pirmohamed, M.4
-
10
-
-
3242723840
-
The MDR1 (ABCB1) gene polymorphism and its clinical implications
-
Ieiri I, Takane H, Otsubo K. The MDR1 (ABCB1) gene polymorphism and its clinical implications. Clin Pharmacokinet. 2004;43(9):553-576
-
(2004)
Clin Pharmacokinet
, vol.43
, Issue.9
, pp. 553-576
-
-
Ieiri, I.1
Takane, H.2
Otsubo, K.3
-
11
-
-
77949392921
-
Evaluation of in vivo P-glycoprotein phenotyping probes: A need for validation
-
Ma JD, et al. Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation. Clin Pharmacokinet. 2010;49(4):223- 237
-
(2010)
Clin Pharmacokinet
, vol.49
, Issue.4
, pp. 223-237
-
-
Ma, J.D.1
-
12
-
-
78650808366
-
The relevance of assessment of intestinal P-gp inhibition using digoxin as an in vivo probe substrate
-
Shi JG, Zhang Y, Yeleswaram S. The relevance of assessment of intestinal P-gp inhibition using digoxin as an in vivo probe substrate. Nat Rev Drug Discov. 2011;10(1):75
-
(2011)
Nat Rev Drug Discov
, vol.10
, Issue.1
, pp. 75
-
-
Shi, J.G.1
Zhang, Y.2
Yeleswaram, S.3
-
13
-
-
0028948839
-
A theoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability
-
Amidon GL, Lennernäs H, Shah VP, Crison JR. A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm Res. 1995;12(3):413-420
-
(1995)
Pharm Res
, vol.12
, Issue.3
, pp. 413-420
-
-
Amidon, G.L.1
Lennernäs, H.2
Shah, V.P.3
Crison, J.R.4
-
15
-
-
0016775803
-
Pharmacokinetics of digoxin in normal subjects after intravenous bolus and infusion doses
-
Koup JR, Greenblatt DJ, Jusko WJ, Smith TW, Koch-Weser J. iPharmacokinetics of digoxin in normal subjects after intravenous bolus and infusion doses. J Pharmacokinet Biopharm. 1975;3(3):181-192
-
(1975)
J Pharmacokinet Biopharm
, vol.3
, Issue.3
, pp. 181-192
-
-
Koup, J.R.1
Greenblatt, D.J.2
Jusko, W.J.3
Smith, T.W.4
Koch-Weser, J.5
-
16
-
-
0026459449
-
Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1)
-
Tanigawara Y, et al. Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1). J Pharmacol Exp Ther. 1992;263(2):840-845
-
(1992)
J Pharmacol Exp Ther
, vol.263
, Issue.2
, pp. 840-845
-
-
Tanigawara, Y.1
-
17
-
-
0029997940
-
Transport and epithelial secretion of the cardiac glycoside, digoxin, by human intestinal epithelial (Caco-2) cells
-
Cavet ME, West M, Simmons NL. Transport and epithelial secretion of the cardiac glycoside, digoxin, by human intestinal epithelial (Caco-2) cells. Br J Pharmacol. 1996;118(6):1389-1396
-
(1996)
Br J Pharmacol
, vol.118
, Issue.6
, pp. 1389-1396
-
-
Cavet, M.E.1
West, M.2
Simmons, N.L.3
-
18
-
-
0029860174
-
Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein
-
Mayer U, et al. Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein. Br J Pharmacol. 1996;119 (5):1038-1044
-
(1996)
Br J Pharmacol
, vol.119
, Issue.5
, pp. 1038-1044
-
-
Mayer, U.1
-
19
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer S, et al. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci USA. 2000;97(7):3473-3478
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.7
, pp. 3473-3478
-
-
Hoffmeyer, S.1
-
20
-
-
0032705762
-
Physiologically based pharmacokinetics of digoxin in mdr1a knockout mice
-
Kawahara M, Sakata A, Miyashita T, Tamai I, Tsuji A. Physiologically based pharmacokinetics of digoxin in mdr1a knockout mice. J Pharm Sci. 1999;88(12):1281-1287
-
(1999)
J Pharm Sci
, vol.88
, Issue.12
, pp. 1281-1287
-
-
Kawahara, M.1
Sakata, A.2
Miyashita, T.3
Tamai, I.4
Tsuji, A.5
-
21
-
-
77952585757
-
-
Center for Drug Evaluation and Research US FDA.,Sep 2006 [cited 2012 Feb 2012],Available from URL
-
Center for Drug Evaluation and Research US FDA. Drug Development and Drug Interactions: Table of Substrates, Inhibitors and Inducers. Sep 2006 [cited 2012 Feb 2012]; Available from URL: http://www.fda.gov/Drugs/ DevelopmentApprovalProcess/DevelopmentResources/DrugInteractionsLabeling/ ucm093664.htm#PgpTransport
-
(2012)
Drug Development and Drug Interactions: Table of Substrates, Inhibitors and Inducers
-
-
-
22
-
-
27544483787
-
Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: Influence of cell line and modulator concentration on P-gp activity
-
Taub ME, Podila L, Ely D, Almeida I. Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity. Drug Metab Dispos. 2005;33(11):1679-1687
-
(2005)
Drug Metab Dispos
, vol.33
, Issue.11
, pp. 1679-1687
-
-
Taub, M.E.1
Podila, L.2
Ely, D.3
Almeida, I.4
-
23
-
-
0033514320
-
Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine
-
Fromm MF, Kim RB, Stein CM, Wilkinson GR, Roden DM. Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine. Circulation. 1999;99(4):552-557
-
(1999)
Circulation
, vol.99
, Issue.4
, pp. 552-557
-
-
Fromm, M.F.1
Kim, R.B.2
Stein, C.M.3
Wilkinson, G.R.4
Roden, D.M.5
-
24
-
-
0030781139
-
Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833
-
Mayer U, Wagenaar E, Dorobek B, Beijnen J, Borst P, Schinkel AH. Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833. J Clin Invest. 1997;100(10):2430-2436
-
(1997)
J Clin Invest
, vol.100
, Issue.10
, pp. 2430-2436
-
-
Mayer, U.1
Wagenaar, E.2
Dorobek, B.3
Beijnen, J.4
Borst, P.5
Schinkel, A.H.6
-
25
-
-
0028825399
-
Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A
-
Schinkel AH, Wagenaar E, van Deemter L, Mol CA, Borst P. Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. J Clin Invest. 1995;96(4):1698-1705
-
(1995)
J Clin Invest
, vol.96
, Issue.4
, pp. 1698-1705
-
-
Schinkel, A.H.1
Wagenaar, E.2
Van Deemter, L.3
Mol, C.A.4
Borst, P.5
-
26
-
-
0033865280
-
Oral bioavailability of digoxin is enhanced by talinolol: Evidence for involvement of intestinal P-glycoprotein
-
Westphal K, et al. Oral bioavailability of digoxin is enhanced by talinolol: evidence for involvement of intestinal P-glycoprotein. Clin Pharmacol Ther. 2000;68(1):6-12
-
(2000)
Clin Pharmacol Ther
, vol.68
, Issue.1
, pp. 6-12
-
-
Westphal, K.1
-
27
-
-
0032754284
-
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
-
[Erratum appears in J Clin Invest 2002 Aug;110(4):571]
-
Greiner B, et al. The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin. [Erratum appears in J Clin Invest 2002 Aug;110(4):571]. J Clin Invest. 1999;104(2):147- 153
-
(1999)
J Clin Invest
, vol.104
, Issue.2
, pp. 147-153
-
-
Greiner, B.1
-
28
-
-
34548295855
-
Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated efflux
-
Igel S, et al. Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated efflux. Clin Pharmacokinet. 2007;46(9):777- 785
-
(2007)
Clin Pharmacokinet
, vol.46
, Issue.9
, pp. 777-785
-
-
Igel, S.1
-
29
-
-
0026092531
-
Digoxin-verapamil interaction: Reduction of biliary but not renal digoxin clearance in humans
-
Hedman A, et al. Digoxin-verapamil interaction: reduction of biliary but not renal digoxin clearance in humans. Clin Pharmacol Ther. 1991;49(3):256-262
-
(1991)
Clin Pharmacol Ther
, vol.49
, Issue.3
, pp. 256-262
-
-
Hedman, A.1
-
30
-
-
3042568988
-
Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers
-
Ding R, et al. Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers. Clin Pharmacol Ther. 2004;76(1):73-84
-
(2004)
Clin Pharmacol Ther
, vol.76
, Issue.1
, pp. 73-84
-
-
Ding, R.1
-
31
-
-
0037373631
-
P-glycoprotein-mediated intestinal and biliary digoxin transport in humans
-
Drescher S, et al. P-glycoprotein-mediated intestinal and biliary digoxin transport in humans. Clin Pharmacol Ther. 2003;73(3):223- 231
-
(2003)
Clin Pharmacol Ther
, vol.73
, Issue.3
, pp. 223-231
-
-
Drescher, S.1
-
32
-
-
0030886124
-
Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain
-
Noé B, Hagenbuch B, Stieger B, Meier PJ. Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain. Proc Natl Acad Sci USA. 1997;94(19):10346-10350
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.19
, pp. 10346-10350
-
-
Noé, B.1
Hagenbuch, B.2
Stieger, B.3
Meier, P.J.4
-
33
-
-
0036291814
-
Organic anion transporter oatp2-mediated interaction between digoxin and amiodarone in the rat liver
-
Kodawara T, et al. Organic anion transporter oatp2-mediated interaction between digoxin and amiodarone in the rat liver. Pharm Res. 2002;19(6):738-743
-
(2002)
Pharm Res
, vol.19
, Issue.6
, pp. 738-743
-
-
Kodawara, T.1
-
34
-
-
1342302110
-
Ex situ inhibition of hepatic uptake and efflux significantly changes metabolism: Hepatic enzymetransporter interplay
-
Lau YY, Wu CY, Okochi H, Benet LZ. Ex situ inhibition of hepatic uptake and efflux significantly changes metabolism: hepatic enzymetransporter interplay. J Pharmacol Exp Ther. 2004;308(3):1040-1045
-
(2004)
J Pharmacol Exp Ther
, vol.308
, Issue.3
, pp. 1040-1045
-
-
Lau, Y.Y.1
Wu, C.Y.2
Okochi, H.3
Benet, L.Z.4
-
35
-
-
79955668560
-
Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin
-
Weiss M, Hung DY, Poenicke K, Roberts MS. Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin. Eur J Pharm Sci. 2008;34(4-5):345-350
-
(2008)
Eur J Pharm Sci
, vol.34
, Issue.4-5
, pp. 345-350
-
-
Weiss, M.1
Hung, D.Y.2
Poenicke, K.3
Roberts, M.S.4
-
36
-
-
77955467372
-
An improved nonlinear model describing the hepatic pharmacokinetics of digoxin: Evidence for two functionally different uptake systems and saturable binding
-
Weiss M, Li P, Roberts MS. An improved nonlinear model describing the hepatic pharmacokinetics of digoxin: evidence for two functionally different uptake systems and saturable binding. Pharm Res. 2010;27(9):1999-2007
-
(2010)
Pharm Res
, vol.27
, Issue.9
, pp. 1999-2007
-
-
Weiss, M.1
Li, P.2
Roberts, M.S.3
-
37
-
-
33748299055
-
The complexity of intestinal absorption and exsorption of digoxin in rats
-
Yao H-M, Chiou WL. The complexity of intestinal absorption and exsorption of digoxin in rats. Int J Pharm. 2006;322(1-2):79-86
-
(2006)
Int J Pharm
, vol.322
, Issue.1-2
, pp. 79-86
-
-
Yao, H.M.1
Chiou, W.L.2
-
38
-
-
38749113348
-
Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells
-
Acharya P, et al. Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells. Drug Metab Dispos 2008;36(2):452-460
-
(2008)
Drug Metab Dispos
, vol.36
, Issue.2
, pp. 452-460
-
-
Acharya, P.1
-
39
-
-
0035125407
-
Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver
-
Kullak-Ublick GA, et al. Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology. 2001;120(2):525-533
-
(2001)
Gastroenterology
, vol.120
, Issue.2
, pp. 525-533
-
-
Kullak-Ublick, G.A.1
-
40
-
-
80054734195
-
Digoxin is not a substrate for organic aniontransporting polypeptide transporters oatp1a2, oatp1b1, oatp1b3, and oatp2b1 but is a substrate for a sodium-dependenttransporter expressed in hek293 cells
-
Taub ME, et al. Digoxin is not a substrate for organic aniontransporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium-dependenttransporter expressed in HEK293 cells. Drug Metab Dispos. 2011;39 (11):2093-2102
-
(2011)
Drug Metab Dispos
, vol.39
, Issue.11
, pp. 2093-2102
-
-
Taub, M.E.1
-
41
-
-
78650730960
-
Characterization of digoxin uptake in sandwich-cultured human hepatocytes
-
Kimoto E, Chupka J, Xiao Y, Bi Y-a, Duignan DB. Characterization of digoxin uptake in sandwich-cultured human hepatocytes. Drug Metab Dispos. 2011;39:47-53
-
(2011)
Drug Metab Dispos
, vol.39
, pp. 47-53
-
-
Kimoto, E.1
Chupka, J.2
Xiao, Y.3
Bi, Y.-A.4
Duignan, D.B.5
-
42
-
-
0031836110
-
Characterization of the uptake of rocuronium and digoxin in human hepatocytes: Carrier specificity and comparison with in vivo data
-
Olinga P, et al. Characterization of the uptake of rocuronium and digoxin in human hepatocytes: carrier specificity and comparison with in vivo data. J Pharmacol Exp Ther. 1998;285(2):506-510
-
(1998)
J Pharmacol Exp Ther
, vol.285
, Issue.2
, pp. 506-510
-
-
Olinga, P.1
-
43
-
-
12144288563
-
Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney
-
Mikkaichi T, et al. Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney. Proc Natl Acad Sci USA. 2004;101(10):3569-3574
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.10
, pp. 3569-3574
-
-
Mikkaichi, T.1
-
44
-
-
33745253947
-
Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin 2 receptor antagonist, in humans
-
Ishiguro N, et al. Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin 2 receptor antagonist, in humans. Drug Metab Dispos. 2006;34(7):1109-1115
-
(2006)
Drug Metab Dispos
, vol.34
, Issue.7
, pp. 1109-1115
-
-
Ishiguro, N.1
-
46
-
-
78649824063
-
Ribosomal protein L3 mediated the transport of digoxin in Xenopus laevis oocyte
-
Kobayashi Y, Kawakami K, Ohbayashi M, Kohyama N, Yamamoto T. Ribosomal protein L3 mediated the transport of digoxin in Xenopus laevis oocyte. J Toxicol Sci. 2010;35(6):827-834
-
(2010)
J Toxicol Sci
, vol.35
, Issue.6
, pp. 827-834
-
-
Kobayashi, Y.1
Kawakami, K.2
Ohbayashi, M.3
Kohyama, N.4
Yamamoto, T.5
-
47
-
-
0042349753
-
Effects of grapefruit juice on intestinal P-glycoprotein: Evaluation using digoxin in humans
-
Parker RB, Yates CR, Soberman JE, Laizure SC. Effects of grapefruit juice on intestinal P-glycoprotein: evaluation using digoxin in humans. Pharmacotherapy. 2003;23(8):979- 987
-
(2003)
Pharmacotherapy
, vol.23
, Issue.8
, pp. 979-987
-
-
Parker, R.B.1
Yates, C.R.2
Soberman, J.E.3
Laizure, S.C.4
-
48
-
-
0037222807
-
Evidence for a non-MDR1 component in digoxin secretion by human intestinal Caco-2 epithelial layers
-
Lowes S, Cavet ME, Simmons NL. Evidence for a non-MDR1 component in digoxin secretion by human intestinal Caco-2 epithelial layers. Eur J Pharmacol. 2003;458(1- 2):49-56
-
(2003)
Eur J Pharmacol
, vol.458
, Issue.1-2
, pp. 49-56
-
-
Lowes, S.1
Cavet, M.E.2
Simmons, N.L.3
-
49
-
-
79959593077
-
Determination of oatp-, ntcp- and octmediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes
-
De Bruyn T, et al. Determination of OATP-, NTCP- and OCTmediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes. Eur J Pharm Sci. 2011;43(4):297-307
-
(2011)
Eur J Pharm Sci
, vol.43
, Issue.4
, pp. 297-307
-
-
De Bruyn, T.1
-
50
-
-
21344436162
-
Role of organic anion transporting polypeptide 2 in pharmacokinetics of digoxin and beta-methyldigoxin in rats
-
Funakoshi S, Murakami T, Yumoto R, Kiribayashi Y, Takano M. Role of organic anion transporting polypeptide 2 in pharmacokinetics of digoxin and beta-methyldigoxin in rats. J Pharm Sci. 2005;94(6):1196-1203
-
(2005)
J Pharm Sci
, vol.94
, Issue.6
, pp. 1196-1203
-
-
Funakoshi, S.1
Murakami, T.2
Yumoto, R.3
Kiribayashi, Y.4
Takano, M.5
-
51
-
-
67649361952
-
Influence of SLCO1B3 gene polymorphism on the pharmacokinetics of digoxinin terminal renal failure
-
Tsujimoto M, Dan Y, Hirata S, Ohtani H, Sawada Y. Influence of SLCO1B3 gene polymorphism on the pharmacokinetics of digoxinin terminal renal failure. Drug Metab. 2008;23(6):406-411
-
(2008)
Drug Metab
, vol.23
, Issue.6
, pp. 406-411
-
-
Tsujimoto, M.1
Dan, Y.2
Hirata, S.3
Ohtani, H.4
Sawada, Y.5
|