-
2
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger S, Loewith R, Hall M. TOR signaling in growth and metabolism. Cell 2006;124:471-84
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.3
-
3
-
-
84863327242
-
The mechanisms of acute rejection revisited
-
Ponticelli C. The mechanisms of acute rejection revisited. J Nephrol 2012;25:150-8
-
(2012)
J Nephrol
, vol.25
, pp. 150-158
-
-
Ponticelli, C.1
-
4
-
-
84893096637
-
Immunoregulatory properties of rapamycin-conditioned monocyte-derived dendritic cells and their role in transplantation
-
Macedo C, Turquist H, Metes D, Thomson AW. Immunoregulatory properties of rapamycin-conditioned monocyte-derived dendritic cells and their role in transplantation. Transplant Res 2012;1:1-16
-
(2012)
Transplant Res
, vol.1
, pp. 1-16
-
-
Macedo, C.1
Turquist, H.2
Metes, D.3
Thomson, A.W.4
-
5
-
-
33845454157
-
Differential pharmacokinetic interaction of tacrolimus and cyclosporine formulations on everolimus
-
Kovarik JM, Curtis JJ, Hricik DE, et al. Differential pharmacokinetic interaction of tacrolimus and cyclosporine formulations on everolimus. Transplant Proc 2006;38: 3456-8
-
(2006)
Transplant Proc
, vol.38
, pp. 3456-3458
-
-
Kovarik, J.M.1
Curtis, J.J.2
Hricik, D.E.3
-
6
-
-
34347220473
-
Defining the role of mtor in cancer
-
Guertin DA, Sabatini DM. Defining the role of mTOR in cancer. Cancer Cell 2007;12:9-22
-
(2007)
Cancer Cell
, vol.12
, pp. 9-22
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
7
-
-
2942724235
-
MTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1 dependent pathways
-
Majumder PK, Febbo PG, Bikoff R, et al. mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1 dependent pathways. Nat Med 2004;10:594-601
-
(2004)
Nat Med
, vol.10
, pp. 594-601
-
-
Majumder, P.K.1
Febbo, P.G.2
Bikoff, R.3
-
8
-
-
0036174289
-
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: Involvement of vascular endothelial growth factor
-
Guba M, von Breitenbuch P, Steinbauer M, et al. Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: Involvement of vascular endothelial growth factor. Nat Med 2002;8: 128-35
-
(2002)
Nat Med
, vol.8
, pp. 128-135
-
-
Guba, M.1
Von Breitenbuch, P.2
Steinbauer, M.3
-
9
-
-
79958166689
-
Herpes viruses and tumours in kidney transplant recipients the role of immunosuppression
-
Ponticelli C. Herpes viruses and tumours in kidney transplant recipients. The role of immunosuppression. Nephrol Dial Transplant 2011;26:1769-75
-
(2011)
Nephrol Dial Transplant
, vol.26
, pp. 1769-1775
-
-
Ponticelli, C.1
-
10
-
-
0042967970
-
Tacrolimus enhances transforming growth factor-beta1 expression and promotes tumor progression
-
Maluccio M, Sharma V, Lagman M, et al. Tacrolimus enhances transforming growth factor-beta1 expression and promotes tumor progression. Transplantation 2003;76: 597-602
-
(2003)
Transplantation
, vol.76
, pp. 597-602
-
-
Maluccio, M.1
Sharma, V.2
Lagman, M.3
-
11
-
-
3242756741
-
Defective DNA mismatch repair in acute myeloid leukaemia/myelodysplastic syndrome after organ transplantation
-
Offman J, Opelz G, Doehler B, et al. Defective DNA mismatch repair in acute myeloid leukaemia/myelodysplastic syndrome after organ transplantation. Blood 2004;104:822-8
-
(2004)
Blood
, vol.104
, pp. 822-828
-
-
Offman, J.1
Opelz, G.2
Doehler, B.3
-
12
-
-
27644436740
-
Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies
-
Kauffman HM, Cherikh WS, Cheng Y, et al. Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies. Transplantation 2005;80: 883-9
-
(2005)
Transplantation
, vol.80
, pp. 883-889
-
-
Kauffman, H.M.1
Cherikh, W.S.2
Cheng, Y.3
-
13
-
-
84864245430
-
Sirolimus and secondary skin-cancer prevention in kidney transplantation
-
Euvrard S, Morelon E, Rostaing L, et al. Sirolimus and secondary skin-cancer prevention in kidney transplantation. N Engl J Med 2012;367:329-39
-
(2012)
N Engl J Med
, vol.367
, pp. 329-339
-
-
Euvrard, S.1
Morelon, E.2
Rostaing, L.3
-
14
-
-
0034973856
-
Human cytomegalovirus up-regulates the phosphatidylinositol-3-kinase (PI3-K) pathway: Inhibition of PI3-K activity inhibits viral replication and virus-induced signalling
-
Johnson RA, Wang X, Ma XL, et al. Human cytomegalovirus up-regulates the phosphatidylinositol-3-kinase (PI3-K) pathway: Inhibition of PI3-K activity inhibits viral replication and virus-induced signalling. J Virol 2001;75:6022-32
-
(2001)
J Virol
, vol.75
, pp. 6022-6032
-
-
Johnson, R.A.1
Wang, X.2
Ma, X.L.3
-
15
-
-
3042818883
-
HCMV activates PI (3)K monocytes and promotes monocyte motility and transendothelial migration in a dose-dependent manner
-
Smith MS, Bentz GL, Smith PM, et al. HCMV activates PI(3)K monocytes and promotes monocyte motility and transendothelial migration in a dose-dependent manner. J Leukoc Biol 2004;76:65-76
-
(2004)
J Leukoc Biol
, vol.76
, pp. 65-76
-
-
Smith, M.S.1
Bentz, G.L.2
Smith, P.M.3
-
16
-
-
33947403537
-
AMPK-mediated inhibition of mTOR kinase is circumvented during immediate-early times of human cytomegalovirus infection
-
Kudchodkar SB, Del Prete GQ, Maguire TG, Alwine JC. AMPK-mediated inhibition of mTOR kinase is circumvented during immediate-early times of human cytomegalovirus infection. J Virol 2007;81: 3649-51
-
(2007)
J Virol
, vol.81
, pp. 3649-3651
-
-
Kudchodkar, S.B.1
Del Prete, G.Q.2
Maguire, T.G.3
Alwine, J.C.4
-
17
-
-
84861818332
-
CMV late phase-induced mTOR activation is essential for efficient virus replication in polarized human macrophages
-
Poglitsch M, Weichhart T, Hecking M, et al. CMV late phase-induced mTOR activation is essential for efficient virus replication in polarized human macrophages. Am J Transplant 2012;12: 1458-68
-
(2012)
Am J Transplant
, vol.12
, pp. 1458-1468
-
-
Poglitsch, M.1
Weichhart, T.2
Hecking, M.3
-
18
-
-
84872083283
-
Everolimus-Treated renal transplant recipients have a more robust CMV-specific CD8+ T-cell response compared with cyclosporine-or mycophenolatetreated patients
-
Havenith SH, Yong SL, van Donselaar-van der Pant KA, et al. Everolimus-Treated renal transplant recipients have a more robust CMV-specific CD8+ T-cell response compared with cyclosporine-or mycophenolatetreated patients. Transplantation 2013;95: 184-91
-
(2013)
Transplantation
, vol.95
, pp. 184-191
-
-
Havenith, S.H.1
Yong, S.L.2
Van Donselaar-Van Der Pant, K.A.3
-
19
-
-
84881370978
-
PI3Kd inhibition augments the efficacy of rapamycin in suppressing proliferation of Epstein-Barr virus (EBV) + B cell lymphomas
-
Furukawa S, Wei L, Krams SM, et al. PI3Kd inhibition augments the efficacy of rapamycin in suppressing proliferation of Epstein-Barr virus (EBV) + B cell lymphomas. Am J Transplant 2013;13: 2035-43
-
(2013)
Am J Transplant
, vol.13
, pp. 2035-2043
-
-
Furukawa, S.1
Wei, L.2
Krams, S.M.3
-
20
-
-
78650826189
-
Anti-BK virus mechanisms of sirolimus and leflunomide alone and in combination: Toward a new therapy for BK virus infection
-
Liacini A, Seamone ME, Muruve DA, Tibbles LA. Anti-BK virus mechanisms of sirolimus and leflunomide alone and in combination: Toward a new therapy for BK virus infection. Transplantation 2010;90: 1450-7
-
(2010)
Transplantation
, vol.90
, pp. 1450-1457
-
-
Liacini, A.1
Seamone, M.E.2
Muruve, D.A.3
Tibbles, L.A.4
-
21
-
-
33744473322
-
Target of rapamycin inhibitors (sirolimus and everolimus) for primary immunosuppression of kidney transplant recipients: A systematic review and meta-Analysis of randomized trials
-
Webster AC, Lee VW, Chapman JR, Craig JC. Target of rapamycin inhibitors (sirolimus and everolimus) for primary immunosuppression of kidney transplant recipients: A systematic review and meta-Analysis of randomized trials. Transplantation 2006;81:1234-48
-
(2006)
Transplantation
, vol.81
, pp. 1234-1248
-
-
Webster, A.C.1
Lee, V.W.2
Chapman, J.R.3
Craig, J.C.4
-
22
-
-
84857194014
-
Cytomegalovirus incidence between everolimus versus mycophenolate in de novo renal transplants: Pooled analysis of three clinical trials
-
Brennan DC, Legendre C, Patel D, et al. Cytomegalovirus incidence between everolimus versus mycophenolate in de novo renal transplants: Pooled analysis of three clinical trials. Am J Transplant 2011;11: 2453-62
-
(2011)
Am J Transplant
, vol.11
, pp. 2453-2462
-
-
Brennan, D.C.1
Legendre, C.2
Patel, D.3
-
23
-
-
84872085198
-
Is cytomegalovirus prophylaxis dispensable in patients receiving an mTOR inhibitor-based immunosuppressioñ A systematic review and meta-Analysis
-
Andrassy J, Hoffmann VS, Rentsch M, et al. Is cytomegalovirus prophylaxis dispensable in patients receiving an mTOR inhibitor-based immunosuppressioñ A systematic review and meta-Analysis. Transplantation 2012;94:1208-17
-
(2012)
Transplantation
, vol.94
, pp. 1208-1217
-
-
Andrassy, J.1
Hoffmann, V.S.2
Rentsch, M.3
-
24
-
-
65549108756
-
An optn analysis of national registry data on treatment of bk virus allograft nephropathy in the united states
-
Dharnidharka VR, Cherikh WS, Abbott KC. An OPTN analysis of national registry data on treatment of BK virus allograft nephropathy in the United States. Transplantation 2009;87:1019-26
-
(2009)
Transplantation
, vol.87
, pp. 1019-1026
-
-
Dharnidharka, V.R.1
Cherikh, W.S.2
Abbott, K.C.3
-
25
-
-
26444501663
-
Resolution of renal allograft-Associated posttransplant lymphoproliferative disorder with the introduction of sirolimus
-
Zaltzman JS, Prasad R, Chun K, Jothy S. Resolution of renal allograft-Associated posttransplant lymphoproliferative disorder with the introduction of sirolimus. Nephrol Dial Transplant 2005;20:1748-51
-
(2005)
Nephrol Dial Transplant
, vol.20
, pp. 1748-1751
-
-
Zaltzman, J.S.1
Prasad, R.2
Chun, K.3
Jothy, S.4
-
26
-
-
20144367584
-
Sirolimus for Kaposi sarcoma in renal transplant recpients
-
Stallone G, Schena A, Infante B, et al. Sirolimus for Kaposi sarcoma in renal transplant recpients. N Engl J Med 2005;352:1317-23
-
(2005)
N Engl J Med
, vol.352
, pp. 1317-1323
-
-
Stallone, G.1
Schena, A.2
Infante, B.3
-
27
-
-
1442325390
-
The mTOR/p70S6K1 pathway regulates vascular smooth muscle cell differentiation
-
Martin KA, Rzuicidlo EM, Merenick BL. et al. The mTOR/p70S6K1 pathway regulates vascular smooth muscle cell differentiation. Am J Cell Physiol 2004;286:C507-17
-
(2004)
Am J Cell Physiol
, vol.286
-
-
Martin, K.A.1
Rzuicidlo, E.M.2
Merenick, B.L.3
-
29
-
-
19244366021
-
Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-Transplant recipients
-
Eisen HJ, Tuzcu EM, Dorent R, et al. Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-Transplant recipients. N Engl J Med 2003;349:847-58
-
(2003)
N Engl J Med
, vol.349
, pp. 847-858
-
-
Eisen, H.J.1
Tuzcu, E.M.2
Dorent, R.3
-
30
-
-
0036691215
-
Effects of sirolimus on plasma lipids, lipoprotein levels, and fatty acid metabolism
-
Morrissett JD, Abdel-Fattah G, Hogeveen R, et al. Effects of sirolimus on plasma lipids, lipoprotein levels, and fatty acid metabolism. J Lipid Res 2002;43:1170-80
-
(2002)
J Lipid Res
, vol.43
, pp. 1170-1180
-
-
Morrissett, J.D.1
Abdel-Fattah, G.2
Hogeveen, R.3
-
31
-
-
0035886214
-
Effects of sirolimus on the metabolism of apoB100-containing lipoproteins in renal transplant patients
-
Hoogeveen R, Ballantyne CM, Pownall HJ. Effects of sirolimus on the metabolism of apoB100-containing lipoproteins in renal transplant patients. Transplantation 2001;72:1244-50
-
(2001)
Transplantation
, vol.72
, pp. 1244-1250
-
-
Hoogeveen, R.1
Ballantyne, C.M.2
Pownall, H.J.3
-
32
-
-
0842291684
-
Everolimus/cyclosporine interactions on bile and biliary excretion of bile salts cholesterol in rats
-
Deters S, Kirchner G, Koal T, et al. Everolimus/cyclosporine interactions on bile and biliary excretion of bile salts cholesterol in rats. Dig Dis Sci 2004;49:30-7
-
(2004)
Dig Dis Sci
, vol.49
, pp. 30-37
-
-
Deters, S.1
Kirchner, G.2
Koal, T.3
-
33
-
-
0033406881
-
A double blind controlled trial for the treatment of dyslipidaemia in renal allograft recipients
-
Lepre F, Rigby R, Hawley C, et al. A double blind controlled trial for the treatment of dyslipidaemia in renal allograft recipients. Clin Transplant 1999;13:520-6
-
(1999)
Clin Transplant
, vol.13
, pp. 520-526
-
-
Lepre, F.1
Rigby, R.2
Hawley, C.3
-
34
-
-
0033549840
-
Treatment of lipid disorders
-
Knopp RM. Treatment of lipid disorders. N Engl J Med 1999;341:498-511
-
(1999)
N Engl J Med
, vol.341
, pp. 498-511
-
-
Knopp, R.M.1
-
35
-
-
0037287596
-
Interactions between cyclosporine and lipid-lowering drugs: Implications for organ transplant recipients
-
Asberg A. Interactions between cyclosporine and lipid-lowering drugs: Implications for organ transplant recipients. Drugs 2003;663:367-78
-
(2003)
Drugs
, vol.663
, pp. 367-378
-
-
Asberg, A.1
-
36
-
-
0033659109
-
Fibrate-induce increase in urea and creatinine: Is gemfibrozil the only innocuous agent
-
Broeders N, Knoop C, Antoine M, et al. Fibrate-induce increase in urea and creatinine: Is gemfibrozil the only innocuous agent? Nephrol Dial Transplant 2000;15: 1993-9
-
(2000)
Nephrol Dial Transplant
, vol.15
, pp. 1993-1999
-
-
Broeders, N.1
Knoop, C.2
Antoine, M.3
-
37
-
-
68249101040
-
Posttransplant anemia: The role of sirolimus
-
Fishbane S, Cohen DJ, Coyne DW, et al. Posttransplant anemia: The role of sirolimus. Kidney Int 2009;76:376-82
-
(2009)
Kidney Int
, vol.76
, pp. 376-382
-
-
Fishbane, S.1
Cohen, D.J.2
Coyne, D.W.3
-
39
-
-
34547699716
-
Incidence of anemia in sirolimus-Treated renal transplant recipients: The importance of preserving renal function
-
Friend P, Russ G, Oberbauer R, et al. Incidence of anemia in sirolimus-Treated renal transplant recipients: The importance of preserving renal function. Transpl Int 2007;20:754-60
-
(2007)
Transpl Int
, vol.20
, pp. 754-760
-
-
Friend, P.1
Russ, G.2
Oberbauer, R.3
-
40
-
-
79952361568
-
Everolimus-based, calcineurin-inhibitor-free regimen in recipients of de-novo kidney transplants: An open-label, randomised, controlled trial
-
Budde K, Becker T, Arns W, et al. Everolimus-based, calcineurin- inhibitor-free regimen in recipients of de-novo kidney transplants: An open-label, randomised, controlled trial. Lancet 2011;377:837-47
-
(2011)
Lancet
, vol.377
, pp. 837-847
-
-
Budde, K.1
Becker, T.2
Arns, W.3
-
41
-
-
80955149553
-
Lymphocele after renal transplantation, a medical complication
-
Minetti EE. Lymphocele after renal transplantation, a medical complication. J Nephrol 2011;24:707-16
-
(2011)
J Nephrol
, vol.24
, pp. 707-716
-
-
Minetti, E.E.1
-
42
-
-
0346732907
-
The impact of sirolimus, mycophenolate mofetil cyclosporine, azathioprine, and steroids on wound healing in 513 kidney transplant recipients
-
Flechner SM, Zhou L, Derweesh I, et al. The impact of sirolimus, mycophenolate mofetil. cyclosporine, azathioprine, and steroids on wound healing in 513 kidney transplant recipients. Transplantation 2003;76:1729-34
-
(2003)
Transplantation
, vol.76
, pp. 1729-1734
-
-
Flechner, S.M.1
Zhou, L.2
Derweesh, I.3
-
43
-
-
67651039979
-
Incidence of delayed graft function and wound healing complications after deceased-donor kidney transplantation is not affected by de novo everolimus
-
Albano L, Berthoux F, Moal MC, et al. Incidence of delayed graft function and wound healing complications after deceased-donor kidney transplantation is not affected by de novo everolimus. Transplantation 2009;88:69-76
-
(2009)
Transplantation
, vol.88
, pp. 69-76
-
-
Albano, L.1
Berthoux, F.2
Moal, M.C.3
-
44
-
-
8744256458
-
A retrospective review of liver transplant patients treated with sirolimus from a single center: An analysis of sirolimus-related complications
-
Montalbano M, Neff GW, Yamashiki N, et al. A retrospective review of liver transplant patients treated with sirolimus from a single center: An analysis of sirolimus-related complications. Transplantation 2004;78:264-8
-
(2004)
Transplantation
, vol.78
, pp. 264-268
-
-
Montalbano, M.1
Neff, G.W.2
Yamashiki, N.3
-
45
-
-
79955634445
-
Everolimus and minimization of cyclosporine in renal transplantation: 24-month follow-up of the everest study
-
Ponticelli C, Salvadori M, Scolari MP, et al. Everolimus and minimization of cyclosporine in renal transplantation: 24-month follow-up of the EVEREST study. Transplantation 2011;91:e72-3
-
(2011)
Transplantation
-
-
Ponticelli, C.1
Salvadori, M.2
Scolari, M.P.3
-
46
-
-
0345118182
-
Oral ulcers in kidney transplant recipients treated with sirolimus and mycophenolate mofetil
-
Van Gelder T, Ter Meulen CG, Hené R, et al. Oral ulcers in kidney transplant recipients treated with sirolimus and mycophenolate mofetil. Transplantation 2003;75:788-91
-
(2003)
Transplantation
, vol.75
, pp. 788-791
-
-
Van Gelder, T.1
Ter Meulen, C.G.2
Hené, R.3
-
47
-
-
0035884211
-
Oral ulcerations in a renal transplant recipient: A mycophenolate mofetil-induced complication
-
Garrigue V, Canet S, Dereure O, et al. Oral ulcerations in a renal transplant recipient: A mycophenolate mofetil-induced complicatioñ Transplantation 2001;72: 968-9
-
(2001)
Transplantation
, vol.72
, pp. 968-969
-
-
Garrigue, V.1
Canet, S.2
Dereure, O.3
-
48
-
-
0036862285
-
Sirolimus (rapamune) in renal transplantation
-
Johnson RW. Sirolimus (Rapamune) in renal transplantation. Curr Opin Nephrol Hypertens 2002;11:603-7
-
(2002)
Curr Opin Nephrol Hypertens
, vol.11
, pp. 603-607
-
-
Johnson, R.W.1
-
49
-
-
38549152701
-
Sympathetic dystrophy associated with sirolimus therapy
-
Molina MG, Diekmann F, Burgos D, et al. Sympathetic dystrophy associated with sirolimus therapy. Transplantation 2008;85: 290-2
-
(2008)
Transplantation
, vol.85
, pp. 290-292
-
-
Molina, M.G.1
Diekmann, F.2
Burgos, D.3
-
50
-
-
84885030203
-
Sirolimus-FKBP12.6 impairs endothelial barrier function through protein kinase C-A activation and disruption of the p120-vascular endothelial cadherin interaction
-
Habib A, Karmali V, Polavarapu R, et al. Sirolimus-FKBP12.6 impairs endothelial barrier function through protein kinase C-A activation and disruption of the p120-vascular endothelial cadherin interaction. Arterioscler Thromb Vasc Biol 2013;33:2425-31
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 2425-2431
-
-
Habib, A.1
Karmali, V.2
Polavarapu, R.3
-
52
-
-
77958551746
-
Pneumonitis associated with mammalian target of rapamycin inhibitors in renal transplant recipients: A single-center experience
-
Errasti P, Izquierdo D, Martín P, et al. Pneumonitis associated with mammalian target of rapamycin inhibitors in renal transplant recipients: A single-center experience. Transplant Proc 2010;42:3053-4
-
(2010)
Transplant Proc
, vol.42
, pp. 3053-3054
-
-
Errasti, P.1
Izquierdo, D.2
Martín, P.3
-
53
-
-
0037356937
-
Thrombotic microangiopathy with sirolimus-based immunosuppression: Potentiation of calcineurin-inhibitor-induced endothelial damage
-
Robson M, Cote I, Abbs I, et al. Thrombotic microangiopathy with sirolimus-based immunosuppression: Potentiation of calcineurin-inhibitor-induced endothelial damage ? Am J Transplant 2003;3:324-7
-
(2003)
Am J Transplant
, vol.3
, pp. 324-327
-
-
Robson, M.1
Cote, I.2
Abbs, I.3
-
54
-
-
34250166544
-
De novo thrombotic microangiopathy. An underrated complication of renal transplantation
-
Ponticelli C. De novo thrombotic microangiopathy. An underrated complication of renal transplantation. Clin Nephrol 2007;67:335-40
-
(2007)
Clin Nephrol
, vol.67
, pp. 335-340
-
-
Ponticelli, C.1
-
55
-
-
33644914494
-
Calcineurin inhibitor-free immunosuppression in renal allograft recipients with thrombotic microangiopathy/ hemolytic uremic syndrome
-
Oyen O, Strøm EH, Midtvedt K, et al. Calcineurin inhibitor-free immunosuppression in renal allograft recipients with thrombotic microangiopathy/ hemolytic uremic syndrome. Am J Transplant 2006;6:412-18
-
(2006)
Am J Transplant
, vol.6
, pp. 412-418
-
-
Oyen, O.1
Strøm, E.H.2
Midtvedt, K.3
-
56
-
-
84864643813
-
Proteinuria after kidney transplantation
-
Ponticelli C, Graziani G. Proteinuria after kidney transplantation. Transpl Int 2012;25: 909-17
-
(2012)
Transpl Int
, vol.25
, pp. 909-917
-
-
Ponticelli, C.1
Graziani, G.2
-
57
-
-
84857050988
-
Everolimus as primary immunosuppression in kidney transplantation: Experience in conversion from calcineurin inhibitors
-
Sánchez-Fructuoso AI, Ruiz JC, Calvo N, et al. Everolimus as primary immunosuppression in kidney transplantation: Experience in conversion from calcineurin inhibitors. Transplantation 2012;93:398-405
-
(2012)
Transplantation
, vol.93
, pp. 398-405
-
-
Sánchez-Fructuoso, A.I.1
Ruiz, J.C.2
Calvo, N.3
-
58
-
-
84873080842
-
The effect of everolimus versus mycophenolate upon proteinuria following kidney transplant and relationship to graft outcomes
-
Wiseman AC, McCague K, Kim Y, et al. The effect of everolimus versus mycophenolate upon proteinuria following kidney transplant and relationship to graft outcomes. Am J Transplant 2013;13:442-9
-
(2013)
Am J Transplant
, vol.13
, pp. 442-449
-
-
Wiseman, A.C.1
McCague, K.2
Kim, Y.3
-
59
-
-
82955226337
-
MTOR inhibitor-Associated proteinuria in kidney transplant recipients
-
Diekmann F, Andrés A, Oppenheimer F. mTOR inhibitor-Associated proteinuria in kidney transplant recipients. Transplant Rev (Orlando) 2012;26:27-9
-
(2012)
Transplant Rev (Orlando
, vol.26
, pp. 27-29
-
-
Diekmann, F.1
Andrés, A.2
Oppenheimer, F.3
-
60
-
-
59249094511
-
Factors associated with proteinuria in renal transplant recipients treated with sirolimus
-
Liew A, Chiang GS, Vathsala A. Factors associated with proteinuria in renal transplant recipients treated with sirolimus. Transpl Int 2009;22:313-22
-
(2009)
Transpl Int
, vol.22
, pp. 313-322
-
-
Liew, A.1
Chiang, G.S.2
Vathsala, A.3
-
61
-
-
31544461508
-
Conversion from calcineurin inhibitors to sirolimus in chronic allograft dysfunction: Changes in glomerular haemodynamics and proteinuria
-
Saurina A, Campistol JM, Piera C, et al. Conversion from calcineurin inhibitors to sirolimus in chronic allograft dysfunction: Changes in glomerular haemodynamics and proteinuria. Nephrol Dial Transplant 2006;21:488-93
-
(2006)
Nephrol Dial Transplant
, vol.21
, pp. 488-493
-
-
Saurina, A.1
Campistol, J.M.2
Piera, C.3
-
62
-
-
0034789534
-
Rapamycin impairs recovery from acute renal failure: Role of cell-cycle arrest and apoptosis of tubular cells
-
Lieberthal W, Fuhro R, Andry CC, et al. Rapamycin impairs recovery from acute renal failure: Role of cell-cycle arrest and apoptosis of tubular cells. Am J Physiol Renal Physiol 2001;281:F693-706
-
(2001)
Am J Physiol Renal Physiol
, vol.281
-
-
Lieberthal, W.1
Fuhro, R.2
Andry, C.C.3
-
63
-
-
33644928466
-
Sirolimus-Associated heavy proteinuria in a renal transplant recipient: Evidence for a tubular mechanism
-
Straathof-Galema L, Wetzels JF, Dijkman HB, et al. Sirolimus-Associated heavy proteinuria in a renal transplant recipient: Evidence for a tubular mechanism. Am J Transplant 2006;2:429
-
(2006)
Am J Transplant
, vol.2
, pp. 429
-
-
Straathof-Galema, L.1
Wetzels, J.F.2
Dijkman, H.B.3
-
64
-
-
74449084959
-
Tubular toxicity in sirolimus-And cyclosporine-based transplant immunosuppression strategies: An ancillary study from a randomized controlled trial
-
Franz S, Regeniter A, Hopfer H, et al. Tubular toxicity in sirolimus-And cyclosporine-based transplant immunosuppression strategies: An ancillary study from a randomized controlled trial. Am J Kidney Dis 2010;55:33
-
(2010)
Am J Kidney Dis
, vol.55
, pp. 33
-
-
Franz, S.1
Regeniter, A.2
Hopfer, H.3
-
65
-
-
60549117111
-
MTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes
-
Vollenbröker B, George B, Wolfgart M, et al. mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes. Am J Physiol Renal Physiol 2009;296:F418
-
(2009)
Am J Physiol Renal Physiol
, vol.296
-
-
Vollenbröker, B.1
George, B.2
Wolfgart, M.3
-
67
-
-
79955538137
-
Sirolimus and proteinuria in renal transplant patients: Evidence for a dose-dependent effect on slit diaphragm-Associated proteins
-
Stallone G, Infante B, Pontrelli P, et al. Sirolimus and proteinuria in renal transplant patients: Evidence for a dose-dependent effect on slit diaphragm-Associated proteins. Transplantation 2011;91:997-1004
-
(2011)
Transplantation
, vol.91
, pp. 997-1004
-
-
Stallone, G.1
Infante, B.2
Pontrelli, P.3
-
68
-
-
33746530366
-
Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: A randomised multicentre study
-
The Rapamune US Study Group
-
Kahan BD. Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: A randomised multicentre study. The Rapamune US Study Group. Lancet 2000;356(9225): 194-202
-
(2000)
Lancet
, vol.356
, Issue.9225
, pp. 194-202
-
-
Kahan, B.D.1
-
69
-
-
9244246780
-
Everolimus (Certican) 12-month safety and efficacy versus mycophenolate mofetil in de novo renal transplant recipients
-
Vitko S, Margreiter R, Weimar W, et al. Everolimus (Certican) 12-month safety and efficacy versus mycophenolate mofetil in de novo renal transplant recipients. Transplantation 2004;78:1532-40
-
(2004)
Transplantation
, vol.78
, pp. 1532-1540
-
-
Vitko, S.1
Margreiter, R.2
Weimar, W.3
-
70
-
-
16244378141
-
Everolimus versus mycophenolate mofetil in the prevention of rejection in de novo renal transplant recipients: A 3-year randomized, multicenter, phase III study
-
Lorber MI, Mulgaonkar S, Butt KM, et al. Everolimus versus mycophenolate mofetil in the prevention of rejection in de novo renal transplant recipients: A 3-year randomized, multicenter, phase III study. Transplantation 2005;80:244-52
-
(2005)
Transplantation
, vol.80
, pp. 244-252
-
-
Lorber, M.I.1
Mulgaonkar, S.2
Butt, K.M.3
-
71
-
-
0035884710
-
Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure
-
Johnson RW, Kreis H, Oberbauer R, et al. Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure. Transplantation 2001;72(5):777-86
-
(2001)
Transplantation
, vol.72
, Issue.5
, pp. 777-786
-
-
Johnson, R.W.1
Kreis, H.2
Oberbauer, R.3
-
72
-
-
2942534405
-
Sirolimus-based therapy following early cyclosporine withdrawal provides significantly improved renal histology and function at 3 years
-
Mota A, Arias M, Taskinen EI, et al. Sirolimus-based therapy following early cyclosporine withdrawal provides significantly improved renal histology and function at 3 years. Am J Transplant 2004;4:953-61
-
(2004)
Am J Transplant
, vol.4
, pp. 953-961
-
-
Mota, A.1
Arias, M.2
Taskinen, E.I.3
-
73
-
-
79961039264
-
Efficacy and safety of early cyclosporine conversion to sirolimus with continued mmf-four-year results of the postconcept study
-
Lebranchu Y, Thierry A, Thervet E, et al. Efficacy and safety of early cyclosporine conversion to sirolimus with continued MMF-four-year results of the Postconcept study. Am J Transplant 2011;11:1665-75
-
(2011)
Am J Transplant
, vol.11
, pp. 1665-1675
-
-
Lebranchu, Y.1
Thierry, A.2
Thervet, E.3
-
74
-
-
37349034394
-
Reduced exposure to calcineurin inhibitors in renal transplantation
-
Ekberg H, Tedesco-Silva H, Demirbas A, et al. Reduced exposure to calcineurin inhibitors in renal transplantation. N Engl J Med 2007;357:2562-7
-
(2007)
N Engl J Med
, vol.357
, pp. 2562-2567
-
-
Ekberg, H.1
Tedesco-Silva, H.2
Demirbas, A.3
-
75
-
-
79961032806
-
The orion study: Comparison of two sirolimus-based regimens versus tacrolimus and mycophenolate mofetil in renal allograft recipients
-
Flechner SM, Glyda M, Cockfield S, et al. The ORION study: Comparison of two sirolimus-based regimens versus tacrolimus and mycophenolate mofetil in renal allograft recipients. Am J Transplant 2011;11: 1633-44
-
(2011)
Am J Transplant
, vol.11
, pp. 1633-1644
-
-
Flechner, S.M.1
Glyda, M.2
Cockfield, S.3
-
76
-
-
84863189669
-
Five-year results of a randomized trial comparing de novo sirolimus and cyclosporine in renal transplantation: The SPIESSER study
-
Lebranchu Y, Snanoudj R, Toupance O, et al. Five-year results of a randomized trial comparing de novo sirolimus and cyclosporine in renal transplantation: The SPIESSER study. Am J Transplant 2012;12: 1801-10
-
(2012)
Am J Transplant
, vol.12
, pp. 1801-1810
-
-
Lebranchu, Y.1
Snanoudj, R.2
Toupance, O.3
-
77
-
-
84878569533
-
A randomized, open-label study of sirolimus versus cyclosporine in primary de novo renal allograft recipients
-
Flechner SM, Gurkan A, Hartmann A, et al. A randomized, open-label study of sirolimus versus cyclosporine in primary de novo renal allograft recipients. Transplantation 2013;95:1233-41
-
(2013)
Transplantation
, vol.95
, pp. 1233-1241
-
-
Flechner, S.M.1
Gurkan, A.2
Hartmann, A.3
-
78
-
-
84861793711
-
Conversion from cyclosporine to everolimus at 4.5 months posttransplant: 3-year results from the randomized ZEUS study
-
Budde K, Lehner F, Sommerer C, et al. Conversion from cyclosporine to everolimus at 4.5 months posttransplant: 3-year results from the randomized ZEUS study. Am J Transplant 2012;12:1528-40
-
(2012)
Am J Transplant
, vol.12
, pp. 1528-1540
-
-
Budde, K.1
Lehner, F.2
Sommerer, C.3
-
79
-
-
84860431997
-
Donor-specific HLA antibodies in a cohort comparing everolimus with cyclosporine after kidney transplantation
-
Liefeldt L, Brakemeier S, Glander P, et al. Donor-specific HLA antibodies in a cohort comparing everolimus with cyclosporine after kidney transplantation. Am J Transplant 2012;12:1192-8
-
(2012)
Am J Transplant
, vol.12
, pp. 1192-1198
-
-
Liefeldt, L.1
Brakemeier, S.2
Glander, P.3
-
80
-
-
59649126728
-
Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the convert trial
-
Schena FP, Pascoe MD, Alberu J, et al. Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial. Transplantation 2009;87:233-42
-
(2009)
Transplantation
, vol.87
, pp. 233-242
-
-
Schena, F.P.1
Pascoe, M.D.2
Alberu, J.3
-
81
-
-
84893096638
-
Therapeutic drug monitoring for everolimus in kidney transplant recipients based on the exposure-efficacy and safety modelling of 12-month data
-
Lorber M, Ponticelli C, Whelchel J, et al. Therapeutic drug monitoring for everolimus in kidney transplant recipients based on the exposure-efficacy and safety modelling of 12-month data. Clin Transplant 2005;45-52
-
(2005)
Clin Transplant
, pp. 45-52
-
-
Lorber, M.1
Ponticelli, C.2
Whelchel, J.3
-
82
-
-
3943072739
-
Everolimus and reduced-exposure cyclosporine in de novo renal-Transplant recipients: A three-year phase II, randomized, multicenter, open-label study
-
Nashan B, Curtis J, Ponticelli C, et al. Everolimus and reduced-exposure cyclosporine in de novo renal-Transplant recipients: A three-year phase II, randomized, multicenter, open-label study. Transplantation 2004;78:1332-40
-
(2004)
Transplantation
, vol.78
, pp. 1332-1340
-
-
Nashan, B.1
Curtis, J.2
Ponticelli, C.3
-
83
-
-
44449145432
-
A randomized trial of steroid avoidance in renal transplant patients treated with everolimus and low-dose cyclosporine
-
Montagnino G, Sandrini S, Iorio B, et al. A randomized trial of steroid avoidance in renal transplant patients treated with everolimus and low-dose cyclosporine. Nephrol Dial Transplant 2008;23:707-14
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 707-714
-
-
Montagnino, G.1
Sandrini, S.2
Iorio, B.3
-
84
-
-
77952945224
-
Everolimus plus reduced-exposure CsA versus mycophenolic acid plus standard-exposure CsA in renal-Transplant recipients
-
Tedesco Silva H Jr, Cibrik D, Johnston T, et al. Everolimus plus reduced-exposure CsA versus mycophenolic acid plus standard-exposure CsA in renal-Transplant recipients. Am J Transplant 2010;10: 1401-13
-
(2010)
Am J Transplant
, vol.10
, pp. 1401-1413
-
-
Tedesco Silva Jr., H.1
Cibrik, D.2
Johnston, T.3
-
85
-
-
73849119625
-
Everolimus with very low-exposure cyclosporine in de novo kidney transplantation: A multicenter, randomized, controlled trial
-
Salvadori M, Scolari MP, Bertoni E, et al. Everolimus with very low-exposure cyclosporine in de novo kidney transplantation: A multicenter, randomized, controlled trial. Transplantation 2009;88: 1194-202
-
(2009)
Transplantation
, vol.88
, pp. 1194-1202
-
-
Salvadori, M.1
Scolari, M.P.2
Bertoni, E.3
-
86
-
-
84884821314
-
Review of combination therapy with mTOR inhibitors and tacrolimus minimization after transplantation
-
Peddi VR, Wiseman A, Chavin K, Slakey D. Review of combination therapy with mTOR inhibitors and tacrolimus minimization after transplantation. Transplant Rev (Orlando) 2013;27:97
-
(2013)
Transplant Rev (Orlando
, vol.27
, pp. 97
-
-
Peddi, V.R.1
Wiseman, A.2
Chavin, K.3
Slakey, D.4
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