Calcineurin inhibitor-free immunosuppression in renal allograft recipients with thrombotic microangiopathy/hemolytic uremic syndrome

American Journal of Transplantation

Volumn 6, Issue 2, 2006, Pages 412-418

  Oyen O ^a   Strom E H ^a   Midtvedt, K ^a   Bentdal, O ^a   Hartmann, A ^a   Bergan, S ^a   Pfeffer, P ^a   Brekke, I B ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Hemolytic uremic syndrome; Immunosuppression; Renal transplantation; Sirolimus; Thrombotic microangiopathy; Thrombotic thrombocytopenic purpura

Indexed keywords

CALCINEURIN INHIBITOR; CORTICOSTEROID; CREATININE; CYCLOSPORIN A; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; RAPAMYCIN; TSUKUBAENOLIDE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; HEMOLYTIC UREMIC SYNDROME; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY ALLOGRAFT REJECTION; KIDNEY TRANSPLANTATION; MALE; PRIORITY JOURNAL; RECIPIENT; RECURRENT DISEASE; SURGICAL TECHNIQUE; THROMBOTIC THROMBOCYTOPENIC PURPURA; WOUND COMPLICATION;

ADULT; CADAVER; CALCINEURIN; FEMALE; HEMOLYTIC-UREMIC SYNDROME; HUMANS; IMMUNOSUPPRESSION; KIDNEY TRANSPLANTATION; LIVING DONORS; MALE; MIDDLE AGED; PERIPHERAL VASCULAR DISEASES; RENAL CIRCULATION; RETROSPECTIVE STUDIES; TISSUE DONORS;

EID: 33644914494     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2005.01184.x     Document Type: Article

References (20)

1. George JN Gilcher RO Smith JW et al Thrombotic thrombocytopenic purpura-hemolytic-uremic syndrome: Diagnosis and management J Clin Apher 1998 13 120 125
2. Miller BW Hmiel SP Schnitzler MA Brennan DC Cyclosporine as cause of thrombotic microangiopathy after renal transplantation Am J Kidney Dis 1997 29 813 814
3. Zarifian A Meleg-Smith S O'Donovan R Tesi RJ Batuman V Cyclosporine-associated thrombotic microangiopathy in renal allografts Kidney Int 1999 55 2457 2466
4. Schwimmer J Nadasdy TA Spitalnik PF Kapaln KL Zand MS De novo thrombotic microangiopathy in renal transplant recipients: A comparison of hemolytic uremic syndrome with localized renal thrombotic microangiopathy Am J Kidney Dis 2003 41 471 479
5. Furlan M Robles R Galbusera M et al Von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome N Engl J Med 1998 339 1578 1584
6. Tsai HM Lian E Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura N Engl J Med 1998 339 1585 1594
7. Moake JL Rudy CK Troll JH et al Unusually large plasma factor VIII: von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura N Engl J Med 1982 307 1432 1435
8. Levy GG Nichols WC Lian EC et al Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura Nature 2001 413 488 494
9. Neumann HP Salzmann M Bohnert-Iwan B et al Haemolytic uraemic syndrome and mutations of the factor H gene: A registry based study of German speaking countries J Med Genet 2003 40 676 681
10. Warwicker P Goodship JA Goodship THJ Von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome N Engl J Med 1999 340 1368 1369
11. Fortin M-C Schurch W Cardinal H Hèbert MJ Complement factor H deficiency in acute allograft glomerulopathy and post-transplant hemolytic uremic syndrome Am J Transplant 2004 4 270 273
12. Grace AA Barradas MA Mikhailidis DP et al Cyclosporine A enhances platelet aggregation Kidney Int 1987 32 889 895
13. Trimarchi HM Truong LD Brennan S Gonzalez JM Wadi NS FK506-associated thrombotic microangiopathy. Report of two cases and review of the literature Transplantation 1999 67 539 544
14. Beaufils H de Groc F Gubler MC et al Hemolytic uremic syndrome in patients with Behcet's disease treated with cyclosporine A: Report of 2 cases Clin Nephrol 1990 34 157 162
15. Nashan B Vincenti F Successful transplantation without recurrence in hemolytic uremic syndrome omitting calcineurin inhibitors for immunosuppression [abstract] Transplantation 1998 65 12 p S92
16. Ducloux D Rebibou J-M Semhoun-Ducloux S et al Recurrence of hemolytic-uremic syndrome in renal transplant recipients: A meta-analysis Transplantation 1998 65 1405 1407
17. Artz MA Steenbergen EJ Hoitsma AJ Monnens LA Wetzels JF Renal transplantation in patients with haemolytic uremic syndrome: High rate of recurrence and increased incidence of rejections Transplantation 2003 76 821 826
18. Pham P-TT Danowitch GM Wilkinson AH et al Inhibitors of ADAMTS13: A potential factor in the cause of thrombotic microangiopathy in a renal allograft recipient Transplantation 2002 74 1077 1080
19. Langer RM Kahan BD Incidence, therapy, and consequences of lymphocele after sirolimus-cyclosporine-prednisone immunosuppression in renal transplant recipients Transplantation 2002 74 804 808
20. Fortin M-C Raymond M-A Madore F et al Increased risk of thrombotic microangiopathy in patients receiving a cyclosporine-sirolimus combination Am J Transplant 2004 4 946 952