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Volumn 63, Issue 2, 2014, Pages 701-714

Podocyte-specific GLUT4-deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 4; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN;

EID: 84893075800     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-0752     Document Type: Article
Times cited : (53)

References (54)
  • 1
    • 0018904662 scopus 로고
    • The acute effect of insulin on heart rate, blood pressure, plasma noradrenaline and urinary albumin excretion. The role of changes in blood glucose
    • Mogensen CE, Christensen NJ, Gundersen HJ. The acute effect of insulin on heart rate, blood pressure, plasma noradrenaline and urinary albumin excretion. The role of changes in blood glucose. Diabetologia 1980;18: 453-457
    • (1980) Diabetologia , vol.18 , pp. 453-457
    • Mogensen, C.E.1    Christensen, N.J.2    Gundersen, H.J.3
  • 2
    • 0031758395 scopus 로고    scopus 로고
    • Insulin resistance precedes microalbuminuria in patients with insulin-dependent diabetes mellitus
    • Ekstrand AV, Groop PH, Grönhagen-Riska C. Insulin resistance precedes microalbuminuria in patients with insulin-dependent diabetes mellitus. Nephrol Dial Transplant 1998;13:3079-3083
    • (1998) Nephrol Dial Transplant , vol.13 , pp. 3079-3083
    • Ekstrand, A.V.1    Groop, P.H.2    Grönhagen-Riska, C.3
  • 3
    • 0027441048 scopus 로고
    • Insulin resistance in insulin-dependent diabetic patients with microalbuminuria
    • Yip J, Mattock MB, Morocutti A, Sethi M, Trevisan R, Viberti G. Insulin resistance in insulin-dependent diabetic patients with microalbuminuria. Lancet 1993;342:883-887
    • (1993) Lancet , vol.342 , pp. 883-887
    • Yip, J.1    Mattock, M.B.2    Morocutti, A.3    Sethi, M.4    Trevisan, R.5    Viberti, G.6
  • 4
    • 0027309409 scopus 로고
    • Insulin resistance, hypertension and microalbuminuria in patients with type 2 (non-insulin-dependent) diabetes mellitus
    • Groop L, Ekstrand A, Forsblom C, et al. Insulin resistance, hypertension and microalbuminuria in patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 1993;36:642-647
    • (1993) Diabetologia , vol.36 , pp. 642-647
    • Groop, L.1    Ekstrand, A.2    Forsblom, C.3
  • 5
    • 33745311841 scopus 로고    scopus 로고
    • Insulin resistance and microalbuminuria: A cross-sectional, case-control study of 158 patients with type 2 diabetes and different degrees of urinary albumin excretion
    • Parvanova AI, Trevisan R, Iliev IP, et al. Insulin resistance and microalbuminuria: a cross-sectional, case-control study of 158 patients with type 2 diabetes and different degrees of urinary albumin excretion. Diabetes 2006;55:1456-1462
    • (2006) Diabetes , vol.55 , pp. 1456-1462
    • Parvanova, A.I.1    Trevisan, R.2    Iliev, I.P.3
  • 6
    • 0028881544 scopus 로고
    • Insulin resistance and abnormal albumin excretion in non-diabetic first-degree relatives of patients with NIDDM
    • Forsblom CM, Eriksson JG, Ekstrand AV, Teppo AM, Taskinen MR, Groop LC. Insulin resistance and abnormal albumin excretion in non-diabetic first-degree relatives of patients with NIDDM. Diabetologia 1995;38: 363-369
    • (1995) Diabetologia , vol.38 , pp. 363-369
    • Forsblom, C.M.1    Eriksson, J.G.2    Ekstrand, A.V.3    Teppo, A.M.4    Taskinen, M.R.5    Groop, L.C.6
  • 7
    • 0027396769 scopus 로고
    • Insulin resistance in family members of insulin-dependent diabetic patients with microalbuminuria
    • Yip J, Mattock M, Sethi M, Morocutti A, Viberti G. Insulin resistance in family members of insulin-dependent diabetic patients with microalbuminuria. Lancet 1993;341:369-370
    • (1993) Lancet , vol.341 , pp. 369-370
    • Yip, J.1    Mattock, M.2    Sethi, M.3    Morocutti, A.4    Viberti, G.5
  • 8
    • 0346939291 scopus 로고    scopus 로고
    • Microalbuminuria is associated with insulin resistance in nondiabetic subjects: The insulin resistance atherosclerosis study
    • Mykkänen L, Zaccaro DJ, Wagenknecht LE, Robbins DC, Gabriel M, Haffner SM. Microalbuminuria is associated with insulin resistance in nondiabetic subjects: the insulin resistance atherosclerosis study. Diabetes 1998;47:793-800
    • (1998) Diabetes , vol.47 , pp. 793-800
    • Mykkänen, L.1    Zaccaro, D.J.2    Wagenknecht, L.E.3    Robbins, D.C.4    Gabriel, M.5    Haffner, S.M.6
  • 9
    • 34548390678 scopus 로고    scopus 로고
    • Spectrum of renal diseases associated with extreme forms of insulin resistance
    • Musso C, Javor E, Cochran E, Balow JE, Gorden P. Spectrum of renal diseases associated with extreme forms of insulin resistance. Clin J Am Soc Nephrol 2006;1:616-622
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 616-622
    • Musso, C.1    Javor, E.2    Cochran, E.3    Balow, J.E.4    Gorden, P.5
  • 10
    • 34848907421 scopus 로고    scopus 로고
    • Actin up: Regulation of podocyte structure and function by components of the actin cytoskeleton
    • Faul C, Asanuma K, Yanagida-Asanuma E, Kim K, Mundel P. Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton. Trends Cell Biol 2007;17:428-437
    • (2007) Trends Cell Biol , vol.17 , pp. 428-437
    • Faul, C.1    Asanuma, K.2    Yanagida-Asanuma, E.3    Kim, K.4    Mundel, P.5
  • 11
    • 32244446658 scopus 로고    scopus 로고
    • The human glomerular podocyte is a novel target for insulin action
    • Coward RJ, Welsh GI, Yang J, et al. The human glomerular podocyte is a novel target for insulin action. Diabetes 2005;54:3095-3102
    • (2005) Diabetes , vol.54 , pp. 3095-3102
    • Coward, R.J.1    Welsh, G.I.2    Yang, J.3
  • 12
    • 44449119048 scopus 로고    scopus 로고
    • Failure to phosphorylate AKT in podocytes from mice with early diabetic nephropathy promotes cell death
    • Tejada T, Catanuto P, Ijaz A, et al. Failure to phosphorylate AKT in podocytes from mice with early diabetic nephropathy promotes cell death. Kidney Int 2008;73:1385-1393
    • (2008) Kidney Int , vol.73 , pp. 1385-1393
    • Tejada, T.1    Catanuto, P.2    Ijaz, A.3
  • 13
    • 77957657608 scopus 로고    scopus 로고
    • Insulin signaling to the glomerular podocyte is critical for normal kidney function
    • Welsh GI, Hale LJ, Eremina V, et al. Insulin signaling to the glomerular podocyte is critical for normal kidney function. Cell Metab 2010;12: 329-340
    • (2010) Cell Metab , vol.12 , pp. 329-340
    • Welsh, G.I.1    Hale, L.J.2    Eremina, V.3
  • 14
    • 78549271719 scopus 로고    scopus 로고
    • Proteinuria, the podocyte, and insulin resistance
    • Fornoni A. Proteinuria, the podocyte, and insulin resistance. N Engl J Med 2010;363:2068-2069
    • (2010) N Engl J Med , vol.363 , pp. 2068-2069
    • Fornoni, A.1
  • 15
    • 0033913213 scopus 로고    scopus 로고
    • Signaling pathways in insulin action: Molecular targets of insulin resistance
    • Pessin JE, Saltiel AR. Signaling pathways in insulin action: molecular targets of insulin resistance. J Clin Invest 2000;106:165-169
    • (2000) J Clin Invest , vol.106 , pp. 165-169
    • Pessin, J.E.1    Saltiel, A.R.2
  • 16
    • 84555195156 scopus 로고    scopus 로고
    • Nutrient sensing, autophagy, and diabetic nephropathy
    • Kume S, Thomas MC, Koya D. Nutrient sensing, autophagy, and diabetic nephropathy. Diabetes 2012;61:23-29
    • (2012) Diabetes , vol.61 , pp. 23-29
    • Kume, S.1    Thomas, M.C.2    Koya, D.3
  • 17
    • 78549248891 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes
    • Eid AA, Ford BM, Block K, et al. AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes. J Biol Chem 2010;285:37503-37512
    • (2010) J Biol Chem , vol.285 , pp. 37503-37512
    • Eid, A.A.1    Ford, B.M.2    Block, K.3
  • 18
    • 79957881425 scopus 로고    scopus 로고
    • Role of mTOR in podocyte function and diabetic nephropathy in humans and mice
    • Gödel M, Hartleben B, Herbach N, et al. Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. J Clin Invest 2011;121: 2197-2209
    • (2011) J Clin Invest , vol.121 , pp. 2197-2209
    • Gödel, M.1    Hartleben, B.2    Herbach, N.3
  • 19
    • 79957927211 scopus 로고    scopus 로고
    • MTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice
    • Inoki K, Mori H, Wang J, et al. mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. J Clin Invest 2011;121:2181-2196
    • (2011) J Clin Invest , vol.121 , pp. 2181-2196
    • Inoki, K.1    Mori, H.2    Wang, J.3
  • 20
    • 34248547559 scopus 로고    scopus 로고
    • Chronic exposure of human glomerular epithelial cells to high glucose concentration results in modulation of high-affinity glucose transporters expression
    • Moutzouris DA, Kitsiou PV, Talamagas AA, Drossopoulou GI, Kassimatis TI, Katsilambros NK. Chronic exposure of human glomerular epithelial cells to high glucose concentration results in modulation of high-affinity glucose transporters expression. Ren Fail 2007;29:353-358
    • (2007) Ren Fail , vol.29 , pp. 353-358
    • Moutzouris, D.A.1    Kitsiou, P.V.2    Talamagas, A.A.3    Drossopoulou, G.I.4    Kassimatis, T.I.5    Katsilambros, N.K.6
  • 22
    • 19944428477 scopus 로고    scopus 로고
    • Characterization of glucose uptake by cultured rat podocytes
    • Lewko B, Bryl E, Witkowski JM, et al. Characterization of glucose uptake by cultured rat podocytes. Kidney Blood Press Res 2005;28:1-7
    • (2005) Kidney Blood Press Res , vol.28 , pp. 1-7
    • Lewko, B.1    Bryl, E.2    Witkowski, J.M.3
  • 23
    • 77953833285 scopus 로고    scopus 로고
    • Transgenic overexpression of GLUT1 in mouse glomeruli produces renal disease resembling diabetic glomerulosclerosis
    • Wang Y, Heilig K, Saunders T, et al. Transgenic overexpression of GLUT1 in mouse glomeruli produces renal disease resembling diabetic glomerulosclerosis. Am J Physiol Renal Physiol 2010;299:F99-F111
    • (2010) Am J Physiol Renal Physiol , vol.299
    • Wang, Y.1    Heilig, K.2    Saunders, T.3
  • 25
    • 77953858179 scopus 로고    scopus 로고
    • Podocyte-specific overexpression of GLUT1 surprisingly reduces mesangial matrix expansion in diabetic nephropathy in mice
    • Zhang H, Schin M, Saha J, et al. Podocyte-specific overexpression of GLUT1 surprisingly reduces mesangial matrix expansion in diabetic nephropathy in mice. Am J Physiol Renal Physiol 2010;299: F91-F98
    • (2010) Am J Physiol Renal Physiol , vol.299
    • Zhang, H.1    Schin, M.2    Saha, J.3
  • 26
    • 0033393822 scopus 로고    scopus 로고
    • Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart
    • Abel ED, Kaulbach HC, Tian R, et al. Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart. J Clin Invest 1999;104:1703-1714
    • (1999) J Clin Invest , vol.104 , pp. 1703-1714
    • Abel, E.D.1    Kaulbach, H.C.2    Tian, R.3
  • 28
    • 34547111533 scopus 로고    scopus 로고
    • Preserved expression of GLUT4 prevents enhanced agonist-induced vascular reactivity and MYPT1 phosphorylation in hypertensive mouse aorta
    • Atkins KB, Prezkop A, Park JL, et al. Preserved expression of GLUT4 prevents enhanced agonist-induced vascular reactivity and MYPT1 phosphorylation in hypertensive mouse aorta. Am J Physiol Heart Circ Physiol 2007;293:H402-H408
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Atkins, K.B.1    Prezkop, A.2    Park, J.L.3
  • 29
    • 51349162919 scopus 로고    scopus 로고
    • The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A
    • Faul C, Donnelly M, Merscher-Gomez S, et al. The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. Nat Med 2008;14:931-938
    • (2008) Nat Med , vol.14 , pp. 931-938
    • Faul, C.1    Donnelly, M.2    Merscher-Gomez, S.3
  • 30
    • 57049154660 scopus 로고    scopus 로고
    • Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy
    • Zhang H, Saha J, Byun J, et al. Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy. Am J Physiol Renal Physiol 2008;295:F1071-F1081
    • (2008) Am J Physiol Renal Physiol , vol.295
    • Zhang, H.1    Saha, J.2    Byun, J.3
  • 31
    • 0141790220 scopus 로고    scopus 로고
    • Evaluation of a thick and thin section method for estimation of podocyte number, glomerular volume, and glomerular volume per podocyte in rat kidney with Wilms' tumor-1 protein used as a podocyte nuclear marker
    • Sanden SK, Wiggins JE, Goyal M, Riggs LK, Wiggins RC. Evaluation of a thick and thin section method for estimation of podocyte number, glomerular volume, and glomerular volume per podocyte in rat kidney with Wilms' tumor-1 protein used as a podocyte nuclear marker. J Am Soc Nephrol 2003;14:2484-2493
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2484-2493
    • Sanden, S.K.1    Wiggins, J.E.2    Goyal, M.3    Riggs, L.K.4    Wiggins, R.C.5
  • 32
    • 84864847127 scopus 로고    scopus 로고
    • Growth-dependent podocyte failure causes glomerulosclerosis
    • Fukuda A, Chowdhury MA, Venkatareddy MP, et al. Growth-dependent podocyte failure causes glomerulosclerosis. J Am Soc Nephrol 2012;23:1351-1363
    • (2012) J Am Soc Nephrol , vol.23 , pp. 1351-1363
    • Fukuda, A.1    Chowdhury, M.A.2    Venkatareddy, M.P.3
  • 33
    • 67651155938 scopus 로고    scopus 로고
    • Participation of mammalian target of rapamycin complex 1 in Toll-like receptor 2-and 4-induced neutrophil activation and acute lung injury
    • Lorne E, Zhao X, Zmijewski JW, et al. Participation of mammalian target of rapamycin complex 1 in Toll-like receptor 2-and 4-induced neutrophil activation and acute lung injury. Am J Respir Cell Mol Biol 2009;41:237-245
    • (2009) Am J Respir Cell Mol Biol , vol.41 , pp. 237-245
    • Lorne, E.1    Zhao, X.2    Zmijewski, J.W.3
  • 34
    • 40949137434 scopus 로고    scopus 로고
    • Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control
    • Kolavennu V, Zeng L, Peng H, Wang Y, Danesh FR. Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control. Diabetes 2008;57:714-723
    • (2008) Diabetes , vol.57 , pp. 714-723
    • Kolavennu, V.1    Zeng, L.2    Peng, H.3    Wang, Y.4    Danesh, F.R.5
  • 35
    • 48249141108 scopus 로고    scopus 로고
    • RhoA/Rho-kinase contribute to the pathogenesis of diabetic renal disease
    • Peng F, Wu D, Gao B, et al. RhoA/Rho-kinase contribute to the pathogenesis of diabetic renal disease. Diabetes 2008;57:1683-1692
    • (2008) Diabetes , vol.57 , pp. 1683-1692
    • Peng, F.1    Wu, D.2    Gao, B.3
  • 36
    • 78649637235 scopus 로고    scopus 로고
    • Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity
    • Liu L, Luo Y, Chen L, et al. Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity. J Biol Chem 2010;285:38362-38373
    • (2010) J Biol Chem , vol.285 , pp. 38362-38373
    • Liu, L.1    Luo, Y.2    Chen, L.3
  • 37
    • 44649105082 scopus 로고    scopus 로고
    • Inhibition of mTOR in combination with doxorubicin in an experimental model of hepatocellular carcinoma
    • Piguet AC, Semela D, Keogh A, et al. Inhibition of mTOR in combination with doxorubicin in an experimental model of hepatocellular carcinoma. J Hepatol 2008;49:78-87
    • (2008) J Hepatol , vol.49 , pp. 78-87
    • Piguet, A.C.1    Semela, D.2    Keogh, A.3
  • 38
    • 78650643890 scopus 로고    scopus 로고
    • Adriamycin nephropathy: A model of focal segmental glomerulosclerosis
    • Lee VW, Harris DC. Adriamycin nephropathy: a model of focal segmental glomerulosclerosis. Nephrology (Carlton) 2011;16:30-38
    • (2011) Nephrology (Carlton) , vol.16 , pp. 30-38
    • Lee, V.W.1    Harris, D.C.2
  • 40
    • 78649391422 scopus 로고    scopus 로고
    • Cellular metabolic stress: Considering how cells respond to nutrient excess
    • Wellen KE, Thompson CB. Cellular metabolic stress: considering how cells respond to nutrient excess. Mol Cell 2010;40:323-332
    • (2010) Mol Cell , vol.40 , pp. 323-332
    • Wellen, K.E.1    Thompson, C.B.2
  • 41
    • 78650510609 scopus 로고    scopus 로고
    • MTOR: From growth signal integration to cancer, diabetes and ageing
    • Zoncu R, Efeyan A, Sabatini DM. mTOR: from growth signal integration to cancer, diabetes and ageing. Nat Rev Mol Cell Biol 2011;12:21-35
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 21-35
    • Zoncu, R.1    Efeyan, A.2    Sabatini, D.M.3
  • 42
    • 73949137331 scopus 로고    scopus 로고
    • Saturated fatty acids induce insulin resistance in human podocytes: Implications for diabetic nephropathy
    • Lennon R, Pons D, Sabin MA, et al. Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy. Nephrol Dial Transplant 2009;24:3288-3296
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 3288-3296
    • Lennon, R.1    Pons, D.2    Sabin, M.A.3
  • 43
    • 73449102497 scopus 로고    scopus 로고
    • Cycle training increased GLUT4 and activation of mammalian target of rapamycin in fast twitch muscle fibers
    • Stuart CA, Howell ME, Baker JD, et al. Cycle training increased GLUT4 and activation of mammalian target of rapamycin in fast twitch muscle fibers. Med Sci Sports Exerc 2010;42:96-106
    • (2010) Med Sci Sports Exerc , vol.42 , pp. 96-106
    • Stuart, C.A.1    Howell, M.E.2    Baker, J.D.3
  • 44
    • 29144490392 scopus 로고    scopus 로고
    • Podocyte depletion causes glomerulosclerosis: Diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene
    • Wharram BL, Goyal M, Wiggins JE, et al. Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene. J Am Soc Nephrol 2005;16:2941-2952
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2941-2952
    • Wharram, B.L.1    Goyal, M.2    Wiggins, J.E.3
  • 45
    • 84862802020 scopus 로고    scopus 로고
    • Translationally controlled tumour protein is associated with podocyte hypertrophy in a mouse model of type 1 diabetes
    • Kim DK, Nam BY, Li JJ, et al. Translationally controlled tumour protein is associated with podocyte hypertrophy in a mouse model of type 1 diabetes. Diabetologia 2012;55:1205-1217
    • (2012) Diabetologia , vol.55 , pp. 1205-1217
    • Kim, D.K.1    Nam, B.Y.2    Li, J.J.3
  • 46
    • 46649112177 scopus 로고    scopus 로고
    • Cardiac restricted overexpression of kinasedead mammalian target of rapamycin (mTOR) mutant impairs the mTORmediated signaling and cardiac function
    • Shen WH, Chen Z, Shi S, et al. Cardiac restricted overexpression of kinasedead mammalian target of rapamycin (mTOR) mutant impairs the mTORmediated signaling and cardiac function. J Biol Chem 2008;283:13842-13849
    • (2008) J Biol Chem , vol.283 , pp. 13842-13849
    • Shen, W.H.1    Chen, Z.2    Shi, S.3
  • 47
    • 33645266951 scopus 로고    scopus 로고
    • Podocyte hypertrophy, "adaptation," and " decompensation" associated with glomerular enlargement and glomerulosclerosis in the aging rat: Prevention by calorie restriction
    • Wiggins JE, Goyal M, Sanden SK, et al. Podocyte hypertrophy, "adaptation," and "decompensation" associated with glomerular enlargement and glomerulosclerosis in the aging rat: prevention by calorie restriction. J Am Soc Nephrol 2005;16:2953-2966
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2953-2966
    • Wiggins, J.E.1    Goyal, M.2    Sanden, S.K.3
  • 48
    • 33846605083 scopus 로고    scopus 로고
    • Sirolimus therapy of focal segmental glomerulosclerosis is associated with nephrotoxicity
    • Cho ME, Hurley JK, Kopp JB. Sirolimus therapy of focal segmental glomerulosclerosis is associated with nephrotoxicity. Am J Kidney Dis 2007;49:310-317
    • (2007) Am J Kidney Dis , vol.49 , pp. 310-317
    • Cho, M.E.1    Hurley, J.K.2    Kopp, J.B.3
  • 49
    • 36249006990 scopus 로고    scopus 로고
    • Rosiglitazone decreases albuminuria in type 2 diabetic patients
    • Miyazaki Y, Cersosimo E, Triplitt C, DeFronzo RA. Rosiglitazone decreases albuminuria in type 2 diabetic patients. Kidney Int 2007;72:1367-1373
    • (2007) Kidney Int , vol.72 , pp. 1367-1373
    • Miyazaki, Y.1    Cersosimo, E.2    Triplitt, C.3    Defronzo, R.A.4
  • 50
    • 36649011357 scopus 로고    scopus 로고
    • Thiazolidinediones provide better renoprotection than insulin in an obese, hypertensive type II diabetic rat model
    • Ohtomo S, Izuhara Y, Takizawa S, et al. Thiazolidinediones provide better renoprotection than insulin in an obese, hypertensive type II diabetic rat model. Kidney Int 2007;72:1512-1519
    • (2007) Kidney Int , vol.72 , pp. 1512-1519
    • Ohtomo, S.1    Izuhara, Y.2    Takizawa, S.3
  • 51
    • 10344240901 scopus 로고    scopus 로고
    • Efficacy and safety of pioglitazone versus metformin in patients with type 2 diabetes mellitus: A double-blind, randomized trial
    • Quartet [corrected] Study Group
    • Schernthaner G, Matthews DR, Charbonnel B, Hanefeld M, Brunetti P; Quartet [corrected] Study Group. Efficacy and safety of pioglitazone versus metformin in patients with type 2 diabetes mellitus: a double-blind, randomized trial. J Clin Endocrinol Metab 2004;89:6068-6076
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 6068-6076
    • Schernthaner, G.1    Matthews, D.R.2    Charbonnel, B.3    Hanefeld, M.4    Brunetti, P.5
  • 52
    • 84859240796 scopus 로고    scopus 로고
    • The anti-proliferative effect of rosiglitazone on angiotensin II-induced vascular smooth muscle cell proliferation is mediated by the mTOR pathway
    • Kim JS, Kim IK, Lee SY, et al. The anti-proliferative effect of rosiglitazone on angiotensin II-induced vascular smooth muscle cell proliferation is mediated by the mTOR pathway. Cell Biol Int 2012;36:305-310
    • (2012) Cell Biol Int , vol.36 , pp. 305-310
    • Kim, J.S.1    Kim, I.K.2    Lee, S.Y.3
  • 53
    • 68449093090 scopus 로고    scopus 로고
    • Rosiglitazone enhances glucose uptake in glomerular podocytes using the glucose transporter GLUT1
    • Lennon R, Welsh GI, Singh A, et al. Rosiglitazone enhances glucose uptake in glomerular podocytes using the glucose transporter GLUT1. Diabetologia 2009;52:1944-1952
    • (2009) Diabetologia , vol.52 , pp. 1944-1952
    • Lennon, R.1    Welsh, G.I.2    Singh, A.3
  • 54
    • 0033580846 scopus 로고    scopus 로고
    • Aldolase mediates the association of F-actin with the insulin-responsive glucose transporter GLUT4
    • Kao AW, Noda Y, Johnson JH, Pessin JE, Saltiel AR. Aldolase mediates the association of F-actin with the insulin-responsive glucose transporter GLUT4. J Biol Chem 1999;274:17742-17747
    • (1999) J Biol Chem , vol.274 , pp. 17742-17747
    • Kao, A.W.1    Noda, Y.2    Johnson, J.H.3    Pessin, J.E.4    Saltiel, A.R.5


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