Insulin resistance precedes microalbuminuria in patients with insulin-dependent diabetes mellitus

Nephrology Dialysis Transplantation

Volumn 13, Issue 12, 1998, Pages 3079-3083

  Ekstrand, Agneta V ^a   Groop, Per Henrik ^a   Grönhagen Riska, Carola ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Diabetic nephropathy; Insulin sensitivity; Microvascular complication

Indexed keywords

ALBUMIN; GLUCOSE; INSULIN;

ADOLESCENT; ADULT; ARTICLE; CALORIMETRY; CLINICAL ARTICLE; CONTROLLED STUDY; GLUCOSE CLAMP TECHNIQUE; GLUCOSE METABOLISM; HUMAN; HYPERTENSION; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESISTANCE; MICROALBUMINURIA; NORMAL HUMAN; PRIORITY JOURNAL;

EID: 0031758395     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/13.12.3079     Document Type: Article

References (24)

1. Andersen AR, Christensen JS, Andersen JK, Kreiner S, Deckert T. Diabetic nephropathy in type I (insulin-dependent) diabetes: an epidemiological study. Diabetologia 1983; 25: 496-501
2. Seaquist E, Goetz F, Barbosa J, Rich S. Evidence for genetic susceptibility to diabetic nephropathy. Diabetes 1987; 36: 105A
3. Mangili R, Bending JJ, Scott G et al. Increased sodium-lithium countertransport activity in red cells of patients with insulin-dependent diabetes and nephropathy. N Engl J Med 1988; 318: 146-150
4. Earle K, Walker J, Hill C, Viberti GC. Familial clustering of cardiovascular disease in patients with insulin-dependent diabetes and nephropathy. N Engl J Med 1992; 326: 673-677
5. Groop L, Ekstrand A, Forsblom C et al. Insulin resistance, hypertension and microalbuminuria in patients with type 2 (non-insulin dependent) diabetes mellitus. Diabetologia 1993; 36: 642-647
6. Ferrannini E, Buzzigoli G, Bonadonna R. Insulin resistance in essential hypertension. N Engl J Med 1987; 317: 350-357
7. Bötker HE, Möller N, Ovesen P et al. Insulin resistance in microvascular angina (syndrome X). Lancet 1993; 342: 136-140
8. DeFronzo RA. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM. Diabetes 1988; 37: 667-687
9. Nosadini R, Manzato E, Soloini A et al. Peripheral, rather than hepatic, insulin resistance and atherogenic lipoprotein phenotype predict cardiovascular complications in NIDDM. Eur J Clin Invest 1994; 24: 258 266
10. Yip J, Mattock MB, Morocutti A, Sethi M, Trevisan R, Viberti GC. Insulin resistance in insulin-dependent diabetic patients with microalbuminuria. Lancet 1993; 342: 883-887
11. Parving HH, Smith UM, Friisberg B, Bonnevie-Nielsen V, Andersen AR. A prospective study of glomerular filtration rate and arterial blood pressure in insulin-dependent diabetics with diabetic nephropathy. Diabetologia 1981; 20: 457-461
12. McNally PG, Burden AC, Swift GF, Walls J, Hearnshaw JR. The prevalence and risk factors associated with the onset of diabetic nephropathy in juvenile-onset (insulin-dependent) diabetics diagnosed under the age of 17 years in Leicestershire 1930-1985. Q J Med 1990; 76: 831-844
13. Janner M, Knill SE, Diem P, Zuppinger KA, Mullis PE. Persistent microalbuminuria in adolescents with type 1 (insulin-dependent) diabetes mellitus is associated to early rather than late puberty: results of a prospective longitudinal study. Eur J Pediatr 1994; 153: 403-408
14. DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979: 237: E214-223
15. Ferrannini E. The theoretical basis for indirect calorimetry: a review. Metabolism 1988; 37: 287-301
16. Shulman GI, Rothman DL, Jue T, Stein P, DeFronzo RA, Shulman RG. Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by (+13)C nuclear magnetic resonance spectroscopy. N Engl J Med 1990; 322: 223-228
17. Parving HH, Hommel E, Mathiesen E et al. Prevalence of microalbuminuria, arterial hypertension, retinopathy and neuropathy in patients with insulin dependent diabetes. Br Med J 1988; 296: 156-160
18. DeFronzo RA, Hendler R, Simonson D. Insulin resistance is a prominent feature of insulin-dependent diabetes. Diabetes 1982; 31: 795-801
19. Yki-Järvinen H, Sahlin K, Ren JM, Koivisto VA. Localisation of rate-limiting defect for glucose disposal in skeletal muscle of insulin-resistant type 1 diabetic patients. Diabetes 1990; 39: 157-167
20. Reavcn GM, Sageman WS, Swenson RS. Development of insulin resistance in normal dogs following alloxan-induced insulin deficiency. Diabetologia 1977; 13: 459-462
21. Bonner-Weir S, Trent DF, Weir GC. Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release. J Clin Invest 1983; 71: 1544-1553
22. Mogensen CE, Christensen CK. Predicting diabetic nephropathy in insulin-dependent patients. N Engl J Med 1984; 311: 89-93
23. Viberti G, Keen H, Wiseman M. Raised arterial pressure in parents of proteinuric insulin dependent diabetics. Br Med J 1987; 295: 515-517
24. Groop P-H, Fagerudd J, Pettersson-Fernholm K, Grönhagen-Riska C. Abnormalities of glucose metabolism in parents of IDDM-patients with diabetic nephropathy. J Am Soc Nephrol 1996; 7: 1358