-
2
-
-
11144354339
-
Prevalence of agerelated macular degeneration in the United States
-
Friedman DS, O'Colmain BJ, Munoz B, et al. Prevalence of agerelated macular degeneration in the United States. Arch Ophthalmol. 2004;122:564-572.
-
(2004)
Arch Ophthalmol.
, vol.122
, pp. 564-572
-
-
Friedman, D.S.1
O'Colmain, B.J.2
Munoz, B.3
-
3
-
-
0034800655
-
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
-
Age-Related Eye Disease Study Research Group
-
Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol. 2001;119:1417-1436.
-
(2001)
Arch Ophthalmol.
, vol.119
, pp. 1417-1436
-
-
-
4
-
-
84863719300
-
Nutritional modulation of agerelated macular degeneration
-
Weikel KA, Chiu CJ, Taylor A. Nutritional modulation of agerelated macular degeneration. Mol Aspects Med. 2012;33:318-375.
-
(2012)
Mol Aspects Med.
, vol.33
, pp. 318-375
-
-
Weikel, K.A.1
Chiu, C.J.2
Taylor, A.3
-
5
-
-
34447250772
-
Association between dietary glycemic index and age-related macular degeneration in nondiabetic participants in the Age-Related Eye Disease Study
-
Chiu CJ, Milton RC, Gensler G, Taylor A. Association between dietary glycemic index and age-related macular degeneration in nondiabetic participants in the Age-Related Eye Disease Study. Am J Clin Nutr. 2007;86:180-188.
-
(2007)
Am J Clin Nutr.
, vol.86
, pp. 180-188
-
-
Chiu, C.J.1
Milton, R.C.2
Gensler, G.3
Taylor, A.4
-
6
-
-
35148817828
-
Dietary carbohydrate and the progression of age-related macular degeneration: A prospective study from the Age-Related Eye Disease Study
-
Chiu CJ, Milton RC, Klein R, Gensler G, Taylor A. Dietary carbohydrate and the progression of age-related macular degeneration: a prospective study from the Age-Related Eye Disease Study. Am J Clin Nutr. 2007;86:1210-1218.
-
(2007)
Am J Clin Nutr.
, vol.86
, pp. 1210-1218
-
-
Chiu, C.J.1
Milton, R.C.2
Klein, R.3
Gensler, G.4
Taylor, A.5
-
8
-
-
31644446394
-
Mouse models of age-related macular degeneration
-
Rakoczy EP, Yu MJ, Nusinowitz S, Chang B, Heckenlively JR. Mouse models of age-related macular degeneration. Exp Eye Res. 2006;82:741-752.
-
(2006)
Exp Eye Res.
, vol.82
, pp. 741-752
-
-
Rakoczy, E.P.1
Yu, M.J.2
Nusinowitz, S.3
Chang, B.4
Heckenlively, J.R.5
-
9
-
-
77954474714
-
Animals as models of age-related macular degeneration: An imperfect measure of the truth
-
Zeiss CJ. Animals as models of age-related macular degeneration: an imperfect measure of the truth. Vet Pathol. 2010;47: 396-413.
-
(2010)
Vet Pathol.
, vol.47
, pp. 396-413
-
-
Zeiss, C.J.1
-
10
-
-
0036453590
-
The role of aging, high fat diet and blue light exposure in an experimental mouse model for basal laminar deposit formation
-
Cousins SW, Espinosa-Heidmann DG, Alexandridou A, Sall J, Dubovy S, Csaky K. The role of aging, high fat diet and blue light exposure in an experimental mouse model for basal laminar deposit formation. Exp Eye Res. 2002;75:543-553.
-
(2002)
Exp Eye Res.
, vol.75
, pp. 543-553
-
-
Cousins, S.W.1
Espinosa-Heidmann, D.G.2
Alexandridou, A.3
Sall, J.4
Dubovy, S.5
Csaky, K.6
-
11
-
-
52349098746
-
Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice
-
Fujihara M, Nagai N, Sussan TE, Biswal S, Handa JT. Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice. PLoS One. 2008;3: e3119.
-
(2008)
PLoS One.
, vol.3
-
-
Fujihara, M.1
Nagai, N.2
Sussan, T.E.3
Biswal, S.4
Handa, J.T.5
-
12
-
-
33644859329
-
Cigarette smoke-related oxidants and the development of sub-RPE deposits in an experimental animal model of dry AMD
-
Espinosa-Heidmann DG, Suner IJ, Catanuto P, Hernandez EP, Marin-Castano ME, Cousins SW. Cigarette smoke-related oxidants and the development of sub-RPE deposits in an experimental animal model of dry AMD. Invest Ophthalmol Vis Sci. 2006;47:729-737.
-
(2006)
Invest Ophthalmol Vis Sci.
, vol.47
, pp. 729-737
-
-
Espinosa-Heidmann, D.G.1
Suner, I.J.2
Catanuto, P.3
Hernandez, E.P.4
Marin-Castano, M.E.5
Cousins, S.W.6
-
13
-
-
38949185692
-
Oxidative damage-induced inflammation initiates age-related macular degeneration
-
Hollyfield JG, Bonilha VL, Rayborn ME, et al. Oxidative damage-induced inflammation initiates age-related macular degeneration. Nat Med. 2008;14:194-198.
-
(2008)
Nat Med.
, vol.14
, pp. 194-198
-
-
Hollyfield, J.G.1
Bonilha, V.L.2
Rayborn, M.E.3
-
14
-
-
84858992894
-
Natural history of agerelated retinal lesions that precede AMD in mice fed high or low glycemic index diets
-
Weikel KA, Fitzgerald P, Shang F, et al. Natural history of agerelated retinal lesions that precede AMD in mice fed high or low glycemic index diets. Invest Ophthalmol Vis Sci. 2012;53: 622-632.
-
(2012)
Invest Ophthalmol Vis Sci.
, vol.53
, pp. 622-632
-
-
Weikel, K.A.1
Fitzgerald, P.2
Shang, F.3
-
15
-
-
84855830535
-
Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in non diabetics)
-
Uchiki T, Weikel KA, Jiao W, et al. Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in non diabetics). Aging Cell. 2012;11:1-13.
-
(2012)
Aging Cell.
, vol.11
, pp. 1-13
-
-
Uchiki, T.1
Weikel, K.A.2
Jiao, W.3
-
16
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
Klein RJ, Zeiss C, Chew EY, et al. Complement factor H polymorphism in age-related macular degeneration. Science. 2005;308:385-389.
-
(2005)
Science.
, vol.308
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
-
17
-
-
17244379811
-
Complement factor H polymorphism and agerelated macular degeneration
-
Edwards AO, Ritter R III, Abel KJ, Manning A, Panhuysen C, Farrer LA. Complement factor H polymorphism and agerelated macular degeneration. Science. 2005;308:421-424.
-
(2005)
Science.
, vol.308
, pp. 421-424
-
-
Edwards, A.O.1
Ritter III, R.2
Abel, K.J.3
Manning, A.4
Panhuysen, C.5
Farrer, L.A.6
-
18
-
-
20244388812
-
Complement factor H variant increases the risk of age-related macular degeneration
-
Haines JL, Hauser MA, Schmidt S, et al. Complement factor H variant increases the risk of age-related macular degeneration. Science. 2005;308:419-421.
-
(2005)
Science.
, vol.308
, pp. 419-421
-
-
Haines, J.L.1
Hauser, M.A.2
Schmidt, S.3
-
19
-
-
21044453724
-
A common haplotype in the complement regulatory gene factor H (HF1/ CFH) predisposes individuals to age-related macular degeneration
-
Hageman GS, Anderson DH, Johnson LV, et al. A common haplotype in the complement regulatory gene factor H (HF1/ CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A. 2005;102:7227-7232.
-
(2005)
Proc Natl Acad Sci U S A.
, vol.102
, pp. 7227-7232
-
-
Hageman, G.S.1
Anderson, D.H.2
Johnson, L.V.3
-
20
-
-
84865282678
-
Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids
-
Shaw PX, Zhang L, Zhang M, et al. Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids. Proc Natl Acad Sci U S A. 2012;109:13757-13762.
-
(2012)
Proc Natl Acad Sci U S A.
, vol.109
, pp. 13757-13762
-
-
Shaw, P.X.1
Zhang, L.2
Zhang, M.3
-
21
-
-
80053904386
-
Complement factor H binds malondialdehyde epitopes and protects from oxidative stress
-
Weismann D, Hartvigsen K, Lauer N, et al. Complement factor H binds malondialdehyde epitopes and protects from oxidative stress. Nature. 2011;478:76-81.
-
(2011)
Nature.
, vol.478
, pp. 76-81
-
-
Weismann, D.1
Hartvigsen, K.2
Lauer, N.3
-
22
-
-
82255162545
-
A rare penetrant mutation in CFH confers high risk of age-related macular degeneration
-
Raychaudhuri S, Iartchouk O, Chin K, et al. A rare penetrant mutation in CFH confers high risk of age-related macular degeneration. Nat Genet. 2011;43:1232-1236.
-
(2011)
Nat Genet.
, vol.43
, pp. 1232-1236
-
-
Raychaudhuri, S.1
Iartchouk, O.2
Chin, K.3
-
23
-
-
36749004311
-
Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction
-
Coffey PJ, Gias C, McDermott CJ, et al. Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction. Proc Natl Acad Sci U S A. 2007;104:16651-16656.
-
(2007)
Proc Natl Acad Sci U S A.
, vol.104
, pp. 16651-16656
-
-
Coffey, P.J.1
Gias, C.2
McDermott, C.J.3
-
24
-
-
0036699540
-
Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H
-
Pickering MC, Cook HT, Warren J, et al. Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H. Nat Genet. 2002;31: 424-428.
-
(2002)
Nat Genet.
, vol.31
, pp. 424-428
-
-
Pickering, M.C.1
Cook, H.T.2
Warren, J.3
-
25
-
-
0344791691
-
Basal linear deposit and large drusen are specific for early age-related maculopathy
-
Curcio CA, Millican CL. Basal linear deposit and large drusen are specific for early age-related maculopathy. Arch Ophthalmol. 1999;117:329-339.
-
(1999)
Arch Ophthalmol.
, vol.117
, pp. 329-339
-
-
Curcio, C.A.1
Millican, C.L.2
-
26
-
-
79955765832
-
Age-related retinopathy in NRF2-deficient mice
-
Zhao Z, Chen Y, Wang J, et al. Age-related retinopathy in NRF2-deficient mice. PLoS One. 2011;6:e19456.
-
(2011)
PLoS One.
, vol.6
-
-
Zhao, Z.1
Chen, Y.2
Wang, J.3
-
27
-
-
84879766289
-
Retinal changes precede visual dysfunction in the complement factor h knockout mouse
-
Williams JA, Greenwood J, Moss SE. Retinal changes precede visual dysfunction in the complement factor h knockout mouse. PLoS One. 2013;8:e68616.
-
(2013)
PLoS One.
, vol.8
-
-
Williams, J.A.1
Greenwood, J.2
Moss, S.E.3
-
28
-
-
84880576637
-
Complement component c3 plays a critical role in protecting the aging retina in a murine model of age-related macular degeneration
-
Hoh Kam J, Lenassi E, Malik TH, Pickering MC, Jeffery G. Complement component c3 plays a critical role in protecting the aging retina in a murine model of age-related macular degeneration. Am J Pathol. 2013;183:480-492.
-
(2013)
Am J Pathol.
, vol.183
, pp. 480-492
-
-
Hoh Kam, J.1
Lenassi, E.2
Malik, T.H.3
Pickering, M.C.4
Jeffery, G.5
-
29
-
-
67649969175
-
Complement factor h is critical in the maintenance of retinal perfusion
-
Lundh von Leithner P, Kam JH, Bainbridge J, et al. Complement factor h is critical in the maintenance of retinal perfusion. Am J Pathol. 2009;175:412-421.
-
(2009)
Am J Pathol.
, vol.175
, pp. 412-421
-
-
von Leithner Lundh, P.1
Kam, J.H.2
Bainbridge, J.3
-
30
-
-
79959218607
-
A dual infection pseudorabies virus conditional reporter approach to identify projections to collateralized neurons in complex neural circuits
-
Card JP, Kobiler O, Ludmir EB, Desai V, Sved AF, Enquist LW. A dual infection pseudorabies virus conditional reporter approach to identify projections to collateralized neurons in complex neural circuits. PLoS One. 2011;6:e21141.
-
(2011)
PLoS One.
, vol.6
-
-
Card, J.P.1
Kobiler, O.2
Ludmir, E.B.3
Desai, V.4
Sved, A.F.5
Enquist, L.W.6
-
31
-
-
39749164920
-
Haematopoietic stem cell release is regulated by circadian oscillations
-
Mendez-Ferrer S, Lucas D, Battista M, Frenette PS. Haematopoietic stem cell release is regulated by circadian oscillations. Nature. 2008;452:442-447.
-
(2008)
Nature.
, vol.452
, pp. 442-447
-
-
Mendez-Ferrer, S.1
Lucas, D.2
Battista, M.3
Frenette, P.S.4
-
32
-
-
84863832833
-
Bone marrow-CNS connections: Implications in the pathogenesis of diabetic retinopathy
-
Yellowlees Douglas J, Bhatwadekar AD, Li Calzi S, et al. Bone marrow-CNS connections: implications in the pathogenesis of diabetic retinopathy. Prog Retin Eye Res. 2012;31:481-494.
-
(2012)
Prog Retin Eye Res.
, vol.31
, pp. 481-494
-
-
Yellowlees Douglas, J.1
Bhatwadekar, A.D.2
Li Calzi, S.3
-
33
-
-
84877734347
-
Hypothalamic programming of systemic ageing involving IKK-beta, NF-kappaB and GnRH
-
Zhang G, Li J, Purkayastha S, et al. Hypothalamic programming of systemic ageing involving IKK-beta, NF-kappaB and GnRH. Nature. 2013;497:211-216.
-
(2013)
Nature.
, vol.497
, pp. 211-216
-
-
Zhang, G.1
Li, J.2
Purkayastha, S.3
-
34
-
-
58349109733
-
Autophagy and exosomes in the aged retinal pigment epithelium: Possible relevance to drusen formation and agerelated macular degeneration
-
Wang AL, Lukas TJ, Yuan M, Du N, Tso MO, Neufeld AH. Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and agerelated macular degeneration. PLoS One. 2009;4:e4160.
-
(2009)
PLoS One.
, vol.4
-
-
Wang, A.L.1
Lukas, T.J.2
Yuan, M.3
Du, N.4
Tso, M.O.5
Neufeld, A.H.6
-
35
-
-
84863722159
-
How does the macula protect itself from oxidative stress?
-
Handa JT. How does the macula protect itself from oxidative stress? Mol Aspects Med. 2012;33:418-435.
-
(2012)
Mol Aspects Med.
, vol.33
, pp. 418-435
-
-
Handa, J.T.1
-
36
-
-
84855952349
-
Autophagy in the retina: A potential role in age-related macular degeneration
-
Mitter SK, Rao HV, Qi X, et al. Autophagy in the retina: a potential role in age-related macular degeneration. Adv Exp Med Biol. 2012;723:83-90.
-
(2012)
Adv Exp Med Biol.
, vol.723
, pp. 83-90
-
-
Mitter, S.K.1
Rao, H.V.2
Qi, X.3
-
37
-
-
84867884105
-
Moderately reduced ATP levels promote oxidative stress and debilitate autophagic and phagocytic capacities in human RPE cells
-
Schutt F, Aretz S, Auffarth GU, Kopitz J. Moderately reduced ATP levels promote oxidative stress and debilitate autophagic and phagocytic capacities in human RPE cells. Invest Ophthalmol Vis Sci. 2012;53:5354-5361.
-
(2012)
Invest Ophthalmol Vis Sci.
, vol.53
, pp. 5354-5361
-
-
Schutt, F.1
Aretz, S.2
Auffarth, G.U.3
Kopitz, J.4
-
38
-
-
33846827097
-
Effects of resistant starch, a non-digestible fermentable fiber, on reducing body fat
-
Keenan MJ, Zhou J, McCutcheon KL, et al. Effects of resistant starch, a non-digestible fermentable fiber, on reducing body fat. Obesity (Silver Spring). 2006;14:1523-1534.
-
(2006)
Obesity (Silver Spring).
, vol.14
, pp. 1523-1534
-
-
Keenan, M.J.1
Zhou, J.2
McCutcheon, K.L.3
-
39
-
-
79951993002
-
Starch with high amylose and low in vitro digestibility increases shortchain fatty acid absorption, reduces peak insulin secretion, and modulates incretin secretion in pigs
-
Regmi PR, van Kempen TA, Matte JJ, Zijlstra RT. Starch with high amylose and low in vitro digestibility increases shortchain fatty acid absorption, reduces peak insulin secretion, and modulates incretin secretion in pigs. J Nutr. 2011;141: 398-405.
-
(2011)
J Nutr.
, vol.141
, pp. 398-405
-
-
Regmi, P.R.1
van Kempen, T.A.2
Matte, J.J.3
Zijlstra, R.T.4
-
40
-
-
79960319428
-
Starch with high amylose content and low in vitro digestibility increases intestinal nutrient flow and microbial fermentation and selectively promotes bifidobacteria in pigs
-
Regmi PR, Metzler-Zebeli BU, Ganzle MG, van Kempen TA, Zijlstra RT. Starch with high amylose content and low in vitro digestibility increases intestinal nutrient flow and microbial fermentation and selectively promotes bifidobacteria in pigs. J Nutr. 2011;141:1273-1280.
-
(2011)
J Nutr.
, vol.141
, pp. 1273-1280
-
-
Regmi, P.R.1
Metzler-Zebeli, B.U.2
Ganzle, M.G.3
van Kempen, T.A.4
Zijlstra, R.T.5
-
41
-
-
70349126762
-
The C3a anaphylatoxin receptor is a key mediator of insulin resistance and functions by modulating adipose tissue macrophage infiltration and activation
-
Mamane Y, Chung Chan C, Lavallee G, et al. The C3a anaphylatoxin receptor is a key mediator of insulin resistance and functions by modulating adipose tissue macrophage infiltration and activation. Diabetes. 2009;58:2006-2017.
-
(2009)
Diabetes.
, vol.58
, pp. 2006-2017
-
-
Mamane, Y.1
Chung Chan, C.2
Lavallee, G.3
-
42
-
-
84881224279
-
Mice lacking C1q are protected from high fat diet-induced hepatic insulin resistance and impaired glucose homeostasis
-
Hillian AD, McMullen MR, Sebastian BM, et al. Mice lacking C1q are protected from high fat diet-induced hepatic insulin resistance and impaired glucose homeostasis. J Biol Chem. 2013;288:22565-22575.
-
(2013)
J Biol Chem.
, vol.288
, pp. 22565-22575
-
-
Hillian, A.D.1
McMullen, M.R.2
Sebastian, B.M.3
-
43
-
-
77449136807
-
Complement factor H is expressed in adipose tissue in association with insulin resistance
-
Moreno-Navarrete JM, Martinez-Barricarte R, Catalan V, et al. Complement factor H is expressed in adipose tissue in association with insulin resistance. Diabetes. 2010;59:200-209.
-
(2010)
Diabetes.
, vol.59
, pp. 200-209
-
-
Moreno-Navarrete, J.M.1
Martinez-Barricarte, R.2
Catalan, V.3
-
44
-
-
44349192752
-
CFH and LOC387715/ ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration
-
Klein ML, Francis PJ, Rosner B, et al. CFH and LOC387715/ ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration. Ophthalmology. 2008; 115:1019-1025.
-
(2008)
Ophthalmology.
, vol.115
, pp. 1019-1025
-
-
Klein, M.L.1
Francis, P.J.2
Rosner, B.3
-
45
-
-
84869019331
-
Can genetic associations change with age? CFH and age-related macular degeneration
-
Adams MK, Simpson JA, Richardson AJ, et al. Can genetic associations change with age? CFH and age-related macular degeneration. Hum Mol Genet. 2012;21:5229-5236.
-
(2012)
Hum Mol Genet.
, vol.21
, pp. 5229-5236
-
-
Adams, M.K.1
Simpson, J.A.2
Richardson, A.J.3
|