Mice lacking C1q are protected from high fat diet-induced hepatic insulin resistance and impaired glucose homeostasis

Journal of Biological Chemistry

Volumn 288, Issue 31, 2013, Pages 22565-22575

  Hillian, Antoinette D ^a   McMullen, Megan R ^a   Sebastian, Becky M ^a   Rowchowdhury, Sanjoy ^a   Kashyap, Sangeeta R ^a   Schauer, Philip R ^a   Kirwan, John P ^a   Feldstein, Ariel E ^b   Nagy, Laura E ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLASSICAL PATHWAY; COMPLEMENT ACTIVATIONS; GLUCOSE HOMEOSTASIS; HEPATIC INSULIN RESISTANCE; HIGH-FAT DIET; INSULIN RESISTANCE; THERAPEUTIC TARGETS;

INSULIN;

NUTRITION;

CLODRONIC ACID; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C3C; DECAY ACCELERATING FACTOR; PROTEIN BID;

ADIPOSE TISSUE; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; COMPLEMENT ACTIVATION; COMPLEMENT CLASSICAL PATHWAY; COMPLEMENT DEFICIENCY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GLUCOSE INTOLERANCE; HUMAN; HUMAN TISSUE; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LEAN BODY WEIGHT; LIPID DIET; LIVER; MALE; METABOLIC DISORDER; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN TARGETING;

ADIPOSE TISSUE; APOPTOSIS; COMPLEMENT; INFLAMMATION; INSULIN RESISTANCE; OBESITY;

ADIPOSE TISSUE; ANIMALS; DIETARY FATS; GLUCOSE; HOMEOSTASIS; INSULIN RESISTANCE; LIVER; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; RECEPTORS, COMPLEMENT;

EID: 84881224279     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.465674     Document Type: Article

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