-
1
-
-
0033918563
-
Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3
-
Dammann R, Li C, Yoon JH, Chin PL, Bates S, Pfeifer GP. Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nat Genet 2000;25: 315-9.
-
(2000)
Nat Genet
, vol.25
, pp. 315-319
-
-
Dammann, R.1
Li, C.2
Yoon, J.H.3
Chin, P.L.4
Bates, S.5
Pfeifer, G.P.6
-
2
-
-
0034327412
-
The 630-kb lung cancer homozygous deletion region on human chromosome 3p21. 3: Identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium
-
Lerman MI, Minna JD. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium. Cancer Res 2000;60:6116-33.
-
(2000)
Cancer Res
, vol.60
, pp. 6116-6133
-
-
Lerman, M.I.1
Minna, J.D.2
-
3
-
-
18144411303
-
Role of the Ras-association domain family 1 tumor suppressor gene in human cancers
-
Agathanggelou A, Cooper WN, Latif F. Role of the Ras-association domain family 1 tumor suppressor gene in human cancers. Cancer Res 2005;65:3497-508.
-
(2005)
Cancer Res
, vol.65
, pp. 3497-3508
-
-
Agathanggelou, A.1
Cooper, W.N.2
Latif, F.3
-
4
-
-
16344389423
-
The tumor suppressor RASSF1A in human carcinogenesis: An update
-
Dammann R, Schagdarsurengin U, Seidel C, Strunnikova M, Rastetter M, Baier K, et al. The tumor suppressor RASSF1A in human carcinogenesis: an update. Histol Histopathol 2005;20:645-63.
-
(2005)
Histol Histopathol
, vol.20
, pp. 645-663
-
-
Dammann, R.1
Schagdarsurengin, U.2
Seidel, C.3
Strunnikova, M.4
Rastetter, M.5
Baier, K.6
-
5
-
-
70349174971
-
The RASSF proteins in cancer; From epigenetic silencing to functional characterization
-
Richter AM, Pfeifer GP, Dammann RH. The RASSF proteins in cancer; from epigenetic silencing to functional characterization. Biochim Biophys Acta 2009;1796:114-28.
-
(2009)
Biochim Biophys Acta
, vol.1796
, pp. 114-128
-
-
Richter, A.M.1
Pfeifer, G.P.2
Dammann, R.H.3
-
6
-
-
8844251504
-
Tumor suppressor RASSF1A is a microtubule-binding protein that stabilizes microtubules and induces G2/M arrest
-
Rong R, Jin W, Zhang J, Sheikh MS, Huang Y. Tumor suppressor RASSF1A is a microtubule-binding protein that stabilizes microtubules and induces G2/M arrest. Oncogene 2004;23:8216-30.
-
(2004)
Oncogene
, vol.23
, pp. 8216-8230
-
-
Rong, R.1
Jin, W.2
Zhang, J.3
Sheikh, M.S.4
Huang, Y.5
-
7
-
-
0344825077
-
Control of microtubule stability by the RASSF1A tumor suppressor
-
Liu L, Tommasi S, Lee DH, Dammann R, Pfeifer GP. Control of microtubule stability by the RASSF1A tumor suppressor. Oncogene 2003;22:8125-36.
-
(2003)
Oncogene
, vol.22
, pp. 8125-8136
-
-
Liu, L.1
Tommasi, S.2
Lee, D.H.3
Dammann, R.4
Pfeifer, G.P.5
-
8
-
-
3042675106
-
RASSF1A interacts with microtubule-associated proteins and modulates microtubule dynamics
-
Dallol A, Agathanggelou A, Fenton SL, Ahmed-Choudhury J, Hesson L, Vos MD, et al. RASSF1A interacts with microtubule-associated proteins and modulates microtubule dynamics. Cancer Res 2004;64: 4112-6.
-
(2004)
Cancer Res
, vol.64
, pp. 4112-4116
-
-
Dallol, A.1
Agathanggelou, A.2
Fenton, S.L.3
Ahmed-Choudhury, J.4
Hesson, L.5
Vos, M.D.6
-
9
-
-
3042655534
-
A role for the RASSF1A tumor suppressor in the regulation of tubulin polymerization and genomic stability
-
Vos MD, Martinez A, Elam C, Dallol A, Taylor BJ, Latif F, et al. A role for the RASSF1A tumor suppressor in the regulation of tubulin polymerization and genomic stability. Cancer Res 2004;64:4244-50.
-
(2004)
Cancer Res
, vol.64
, pp. 4244-4250
-
-
Vos, M.D.1
Martinez, A.2
Elam, C.3
Dallol, A.4
Taylor, B.J.5
Latif, F.6
-
10
-
-
24344435500
-
The RASSF1A isoformof RASSF1 promotes microtubule stability and suppresses tumorigenesis
-
van der Weyden L, Tachibana KK, Gonzalez MA, Adams DJ, Ng BL, Petty R, et al. The RASSF1A isoformof RASSF1 promotes microtubule stability and suppresses tumorigenesis. Mol Cell Biol 2005;25: 8356-67.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8356-8367
-
-
Van Der Weyden, L.1
Tachibana, K.K.2
Gonzalez, M.A.3
Adams, D.J.4
Ng, B.L.5
Petty, R.6
-
11
-
-
0036264815
-
The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation
-
Shivakumar L, Minna J, Sakamaki T, Pestell R, White MA. The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation. Mol Cell Biol 2002;22:4309-18.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4309-4318
-
-
Shivakumar, L.1
Minna, J.2
Sakamaki, T.3
Pestell, R.4
White, M.A.5
-
12
-
-
1642602695
-
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APCCdc20 complex
-
Song MS, Song SJ, Ayad NG, Chang JS, Lee JH, Hong HK, et al. The tumour suppressor RASSF1A regulates mitosis by inhibiting the APCCdc20 complex. Nat Cell Biol 2004;6:129-37.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 129-137
-
-
Song, M.S.1
Song, S.J.2
Ayad, N.G.3
Chang, J.S.4
Lee, J.H.5
Hong, H.K.6
-
13
-
-
9144262332
-
Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene
-
Fenton SL, Dallol A, Agathanggelou A, Hesson L, Ahmed-Choudhury J, Baksh S, et al. Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene. Cancer Res 2004;64:102-7.
-
(2004)
Cancer Res
, vol.64
, pp. 102-107
-
-
Fenton, S.L.1
Dallol, A.2
Agathanggelou, A.3
Hesson, L.4
Ahmed-Choudhury, J.5
Baksh, S.6
-
14
-
-
16844381200
-
Transcriptional regulation of cyclin A2 by RASSF1A through the enhanced binding of p120E4F to the cyclin A2 promoter
-
Ahmed-Choudhury J, Agathanggelou A, Fenton SL, Ricketts C, Clark GJ, Maher ER, et al. Transcriptional regulation of cyclin A2 by RASSF1A through the enhanced binding of p120E4F to the cyclin A2 promoter. Cancer Res 2005;65:2690-7.
-
(2005)
Cancer Res
, vol.65
, pp. 2690-2697
-
-
Ahmed-Choudhury, J.1
Agathanggelou, A.2
Fenton, S.L.3
Ricketts, C.4
Clark, G.J.5
Maher, E.R.6
-
15
-
-
46949093338
-
The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex
-
Song MS, Song SJ, Kim SY, Oh HJ, Lim DS. The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex. EMBO J 2008;27:1863-74.
-
(2008)
EMBO J
, vol.27
, pp. 1863-1874
-
-
Song, M.S.1
Song, S.J.2
Kim, S.Y.3
Oh, H.J.4
Lim, D.S.5
-
16
-
-
36849052501
-
Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation
-
Rong R, Jiang LY, Sheikh MS, Huang Y. Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation. Oncogene 2007;26:7700-8.
-
(2007)
Oncogene
, vol.26
, pp. 7700-7708
-
-
Rong, R.1
Jiang, L.Y.2
Sheikh, M.S.3
Huang, Y.4
-
17
-
-
43749089372
-
Skp2 regulates the antiproliferative function of the tumor suppressor RASSF1A via ubiquitin-mediated degradation at the G1-S transition
-
Song MS, Song SJ, Kim SJ, Nakayama K, Nakayama KI, Lim DS. Skp2 regulates the antiproliferative function of the tumor suppressor RASSF1A via ubiquitin-mediated degradation at the G1-S transition. Oncogene 2008;27:3176-85.
-
(2008)
Oncogene
, vol.27
, pp. 3176-3185
-
-
Song, M.S.1
Song, S.J.2
Kim, S.J.3
Nakayama, K.4
Nakayama, K.I.5
Lim, D.S.6
-
18
-
-
46549087092
-
The tumour suppressor RASSF1A is a novel substrate of PKC
-
Verma SK, Ganesan TS, Parker PJ. The tumour suppressor RASSF1A is a novel substrate of PKC. FEBS Lett 2008;582:2270-6.
-
(2008)
FEBS Lett
, vol.582
, pp. 2270-2276
-
-
Verma, S.K.1
Ganesan, T.S.2
Parker, P.J.3
-
19
-
-
57649102412
-
NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis
-
Vichalkovski A, Gresko E, Cornils H, Hergovich A, Schmitz D, Hemmings BA. NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis. Curr Biol 2008;18: 1889-95.
-
(2008)
Curr Biol
, vol.18
, pp. 1889-1895
-
-
Vichalkovski, A.1
Gresko, E.2
Cornils, H.3
Hergovich, A.4
Schmitz, D.5
Hemmings, B.A.6
-
20
-
-
72249088778
-
Aurora B-mediated phosphorylation of RASSF1A maintains proper cytokinesis by recruiting Syntaxin16 to the midzone and midbody
-
Song SJ, Kim SJ, Song MS, Lim DS. Aurora B-mediated phosphorylation of RASSF1A maintains proper cytokinesis by recruiting Syntaxin16 to the midzone and midbody. Cancer Res 2009;69:8540-4.
-
(2009)
Cancer Res
, vol.69
, pp. 8540-8544
-
-
Song, S.J.1
Kim, S.J.2
Song, M.S.3
Lim, D.S.4
-
21
-
-
74549189337
-
New insights into checkpoint kinase 1 in the DNA damage response signaling network
-
Dai Y, Grant S. New insights into checkpoint kinase 1 in the DNA damage response signaling network. Clin Cancer Res 2010;16: 376-83.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 376-383
-
-
Dai, Y.1
Grant, S.2
-
22
-
-
0043066731
-
Regulating mammalian checkpoints through Cdc25 inactivation
-
Donzelli M, Draetta GF. Regulating mammalian checkpoints through Cdc25 inactivation. EMBO Rep 2003;4:671-7.
-
(2003)
EMBO Rep
, vol.4
, pp. 671-677
-
-
Donzelli, M.1
Draetta, G.F.2
-
23
-
-
0034967556
-
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human CHK1
-
Zhao H, Piwnica-Worms H. ATR-mediated checkpoint pathways regulate phosphorylation and activation of human CHK1. Mol Cell Biol 2001;21:4129-39.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4129-4139
-
-
Zhao, H.1
Piwnica-Worms, H.2
-
24
-
-
0033600182
-
Cell-cycle-dependent and ATM-independent expression of human CHK1 kinase
-
Kaneko YS, Watanabe N,Morisaki H, Akita H, Fujimoto A, Tominaga K, et al. Cell-cycle-dependent and ATM-independent expression of human CHK1 kinase. Oncogene 1999;18:3673-81.
-
(1999)
Oncogene
, vol.18
, pp. 3673-3681
-
-
Kaneko, Y.S.1
Watanabe, N.2
Morisaki, H.3
Akita, H.4
Fujimoto, A.5
Tominaga, K.6
-
25
-
-
33747083495
-
Checkpoint kinase 1 (CHK1) is required for mitotic progression through negative regulation of polo-like kinase 1 (Plk1)
-
Tang J, Erikson RL, Liu X. Checkpoint kinase 1 (CHK1) is required for mitotic progression through negative regulation of polo-like kinase 1 (Plk1). Proc Natl Acad Sci U S A 2006;103:11964-9.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 11964-11969
-
-
Tang, J.1
Erikson, R.L.2
Liu, X.3
-
26
-
-
0037073737
-
Checkpoint kinase 2 (Chk2) monomers or dimers phosphorylate Cdc25C after DNA damage regardless of threonine 68 phosphorylation
-
Ahn J, Prives C. Checkpoint kinase 2 (Chk2) monomers or dimers phosphorylate Cdc25C after DNA damage regardless of threonine 68 phosphorylation. J Biol Chem 2002;277:48418-26.
-
(2002)
J Biol Chem
, vol.277
, pp. 48418-48426
-
-
Ahn, J.1
Prives, C.2
-
27
-
-
0034142034
-
The human homologs of checkpoint kinases CHK1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
-
Shieh SY, Ahn J, Tamai K, Taya Y, Prives C. The human homologs of checkpoint kinases CHK1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev 2000;14: 289-300.
-
(2000)
Genes Dev
, vol.14
, pp. 289-300
-
-
Shieh, S.Y.1
Ahn, J.2
Tamai, K.3
Taya, Y.4
Prives, C.5
-
28
-
-
38649118240
-
CHK1 is a histone H3 threonine 11 kinase that regulates DNA damageinduced transcriptional repression
-
Shimada M, Niida H, Zineldeen DH, Tagami H, Tanaka M, Saito H, et al. CHK1 is a histone H3 threonine 11 kinase that regulates DNA damageinduced transcriptional repression. Cell 2008;132:221-32.
-
(2008)
Cell
, vol.132
, pp. 221-232
-
-
Shimada, M.1
Niida, H.2
Zineldeen, D.H.3
Tagami, H.4
Tanaka, M.5
Saito, H.6
-
29
-
-
0037013243
-
Determination of substrate motifs for human CHK1 and hCds1/Chk2 by the oriented peptide library approach
-
O'Neill T, Giarratani L, Chen P, Iyer L, Lee CH, Bobiak M, et al. Determination of substrate motifs for human CHK1 and hCds1/Chk2 by the oriented peptide library approach. J Biol Chem 2002;277: 16102-15.
-
(2002)
J Biol Chem
, vol.277
, pp. 16102-16115
-
-
O'Neill, T.1
Giarratani, L.2
Chen, P.3
Iyer, L.4
Lee, C.H.5
Bobiak, M.6
-
31
-
-
0034677597
-
The 1. 7 A crystal structure of human cell cycle checkpoint kinase CHK1: Implications for CHK1 regulation
-
Chen P, Luo C, Deng Y, Ryan K, Register J, Margosiak S, et al. The 1.7 A crystal structure of human cell cycle checkpoint kinase CHK1: implications for CHK1 regulation. Cell 2000;100:681-92.
-
(2000)
Cell
, vol.100
, pp. 681-692
-
-
Chen, P.1
Luo, C.2
Deng, Y.3
Ryan, K.4
Register, J.5
Margosiak, S.6
-
32
-
-
33746948393
-
Claspin operates downstream of TopBP1 to direct ATR signaling towards CHK1 activation
-
Liu S, Bekker-Jensen S, Mailand N, Lukas C, Bartek J, Lukas J. Claspin operates downstream of TopBP1 to direct ATR signaling towards CHK1 activation. Mol Cell Biol 2006;26:6056-64.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 6056-6064
-
-
Liu, S.1
Bekker-Jensen, S.2
Mailand, N.3
Lukas, C.4
Bartek, J.5
Lukas, J.6
-
33
-
-
79953196150
-
Cullin-4A. DNA damage-binding protein 1 E3 ligase complex targets tumor suppressor RASSF1A for degradation during mitosis
-
Jiang L, Rong R, Sheikh MS, Huang Y. Cullin-4A.DNA damage-binding protein 1 E3 ligase complex targets tumor suppressor RASSF1A for degradation during mitosis. J Biol Chem 2011;286:6971-8.
-
(2011)
J Biol Chem
, vol.286
, pp. 6971-6978
-
-
Jiang, L.1
Rong, R.2
Sheikh, M.S.3
Huang, Y.4
-
34
-
-
13144282737
-
Atm-dependent interactions of a mammalian CHK1 homolog with meiotic chromosomes
-
Flaggs G, Plug AW, Dunks KM, Mundt KE, Ford JC, Quiggle MR, et al. Atm-dependent interactions of a mammalian CHK1 homolog with meiotic chromosomes. Curr Biol 1997;7:977-86.
-
(1997)
Curr Biol
, vol.7
, pp. 977-986
-
-
Flaggs, G.1
Plug, A.W.2
Dunks, K.M.3
Mundt, K.E.4
Ford, J.C.5
Quiggle, M.R.6
-
35
-
-
0030867582
-
Conservation of the CHK1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
-
Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, et al. Conservation of the CHK1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 1997;277:1497-501.
-
(1997)
Science
, vol.277
, pp. 1497-1501
-
-
Sanchez, Y.1
Wong, C.2
Thoma, R.S.3
Richman, R.4
Wu, Z.5
Piwnica-Worms, H.6
-
36
-
-
27744563298
-
High frequency somatic mutations in RASSF1A in nasopharyngeal carcinoma
-
Pan ZG, Kashuba VI, Liu XQ, Shao JY, Zhang RH, Jiang JH, et al. High frequency somatic mutations in RASSF1A in nasopharyngeal carcinoma. Cancer Biol Ther 2005;4:1116-22.
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 1116-1122
-
-
Pan, Z.G.1
Kashuba, V.I.2
Liu, X.Q.3
Shao, J.Y.4
Zhang, R.H.5
Jiang, J.H.6
-
37
-
-
0003880161
-
-
4th ed. New York: Garland Publishing
-
Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. Molecular biology of the cell. 4th ed. New York: Garland Publishing; 2002.
-
(2002)
Molecular Biology of the Cell
-
-
Alberts, B.1
Johnson, A.2
Lewis, J.3
Raff, M.4
Roberts, K.5
Walter, P.6
-
38
-
-
0028118917
-
Microtubule organization and dynamics dependent on microtubule-associated proteins
-
Hirokawa N. Microtubule organization and dynamics dependent on microtubule-associated proteins. Curr Opin Cell Biol 1994;6:74-81.
-
(1994)
Curr Opin Cell Biol
, vol.6
, pp. 74-81
-
-
Hirokawa, N.1
-
39
-
-
0034826896
-
Regulation of microtubule-associated proteins
-
Cassimeris L, Spittle C. Regulation of microtubule-associated proteins. Int Rev Cytol 2001;210:163-226.
-
(2001)
Int Rev Cytol
, vol.210
, pp. 163-226
-
-
Cassimeris, L.1
Spittle, C.2
|