-
3
-
-
2342453921
-
Death receptors in chemotherapy and cancer
-
Debatin K.M., and Krammer P.H. Death receptors in chemotherapy and cancer. Oncogene 23 (2004) 2950-2966
-
(2004)
Oncogene
, vol.23
, pp. 2950-2966
-
-
Debatin, K.M.1
Krammer, P.H.2
-
4
-
-
20444414891
-
The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death
-
Baksh S., Tommasi S., Fenton S., Yu V.C., Martins L.M., Pfeifer G.P., Latif F., Downward J., and Neel B.G. The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death. Mol. Cell 18 (2005) 637-650
-
(2005)
Mol. Cell
, vol.18
, pp. 637-650
-
-
Baksh, S.1
Tommasi, S.2
Fenton, S.3
Yu, V.C.4
Martins, L.M.5
Pfeifer, G.P.6
Latif, F.7
Downward, J.8
Neel, B.G.9
-
5
-
-
18144411303
-
Role of the Ras-association domain family 1 tumor suppressor gene in human cancers
-
Agathanggelou A., Cooper W.N., and Latif F. Role of the Ras-association domain family 1 tumor suppressor gene in human cancers. Cancer Res. 65 (2005) 3497-3508
-
(2005)
Cancer Res.
, vol.65
, pp. 3497-3508
-
-
Agathanggelou, A.1
Cooper, W.N.2
Latif, F.3
-
6
-
-
1642602695
-
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
-
Song M.S., Song S.J., Ayad N.G., Chang J.S., Lee J.H., Hong H.K., Lee H., Choi N., Kim J., Kim H., et al. The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex. Nat. Cell Biol. 6 (2004) 129-137
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 129-137
-
-
Song, M.S.1
Song, S.J.2
Ayad, N.G.3
Chang, J.S.4
Lee, J.H.5
Hong, H.K.6
Lee, H.7
Choi, N.8
Kim, J.9
Kim, H.10
-
7
-
-
33645050117
-
Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis
-
Oh H.J., Lee K.K., Song S.J., Jin M.S., Song M.S., Lee J.H., Im C.R., Lee J.O., Yonehara S., and Lim D.S. Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis. Cancer Res. 66 (2006) 2562-2569
-
(2006)
Cancer Res.
, vol.66
, pp. 2562-2569
-
-
Oh, H.J.1
Lee, K.K.2
Song, S.J.3
Jin, M.S.4
Song, M.S.5
Lee, J.H.6
Im, C.R.7
Lee, J.O.8
Yonehara, S.9
Lim, D.S.10
-
8
-
-
34748812613
-
RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein
-
Matallanas D., Romano D., Yee K., Meissl K., Kucerova L., Piazzolla D., Baccarini M., Vass J.K., Kolch W., and O'Neill E. RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein. Mol. Cell 27 (2007) 962-975
-
(2007)
Mol. Cell
, vol.27
, pp. 962-975
-
-
Matallanas, D.1
Romano, D.2
Yee, K.3
Meissl, K.4
Kucerova, L.5
Piazzolla, D.6
Baccarini, M.7
Vass, J.K.8
Kolch, W.9
O'Neill, E.10
-
9
-
-
40149111984
-
MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation
-
Praskova M., Xia F., and Avruch J. MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation. Curr. Biol. 18 (2008) 311-321
-
(2008)
Curr. Biol.
, vol.18
, pp. 311-321
-
-
Praskova, M.1
Xia, F.2
Avruch, J.3
-
10
-
-
16444373346
-
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1
-
Chan E.H., Nousiainen M., Chalamalasetty R.B., Schafer A., Nigg E.A., and Sillje H.H. The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. Oncogene 24 (2005) 2076-2086
-
(2005)
Oncogene
, vol.24
, pp. 2076-2086
-
-
Chan, E.H.1
Nousiainen, M.2
Chalamalasetty, R.B.3
Schafer, A.4
Nigg, E.A.5
Sillje, H.H.6
-
11
-
-
33847080309
-
Centrosome-associated NDR kinase regulates centrosome duplication
-
Hergovich A., Lamla S., Nigg E.A., and Hemmings B.A. Centrosome-associated NDR kinase regulates centrosome duplication. Mol. Cell 25 (2007) 625-634
-
(2007)
Mol. Cell
, vol.25
, pp. 625-634
-
-
Hergovich, A.1
Lamla, S.2
Nigg, E.A.3
Hemmings, B.A.4
-
13
-
-
0033607636
-
Ndr protein kinase is regulated by phosphorylation on two conserved sequence motifs
-
Millward T.A., Hess D., and Hemmings B.A. Ndr protein kinase is regulated by phosphorylation on two conserved sequence motifs. J. Biol. Chem. 274 (1999) 33847-33850
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33847-33850
-
-
Millward, T.A.1
Hess, D.2
Hemmings, B.A.3
-
14
-
-
4143117852
-
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
-
Bichsel S.J., Tamaskovic R., Stegert M.R., and Hemmings B.A. Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein. J. Biol. Chem. 279 (2004) 35228-35235
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 35228-35235
-
-
Bichsel, S.J.1
Tamaskovic, R.2
Stegert, M.R.3
Hemmings, B.A.4
-
15
-
-
28544435761
-
Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3
-
Stegert M.R., Hergovich A., Tamaskovic R., Bichsel S.J., and Hemmings B.A. Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3. Mol. Cell. Biol. 25 (2005) 11019-11029
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 11019-11029
-
-
Stegert, M.R.1
Hergovich, A.2
Tamaskovic, R.3
Bichsel, S.J.4
Hemmings, B.A.5
-
16
-
-
0029790143
-
Newly identified stress-responsive protein kinases, Krs-1 and Krs-2
-
Taylor L.K., Wang H.C., and Erikson R.L. Newly identified stress-responsive protein kinases, Krs-1 and Krs-2. Proc. Natl. Acad. Sci. USA 93 (1996) 10099-10104
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10099-10104
-
-
Taylor, L.K.1
Wang, H.C.2
Erikson, R.L.3
-
17
-
-
11144267126
-
Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1
-
O'Neill E., Rushworth L., Baccarini M., and Kolch W. Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1. Science 306 (2004) 2267-2270
-
(2004)
Science
, vol.306
, pp. 2267-2270
-
-
O'Neill, E.1
Rushworth, L.2
Baccarini, M.3
Kolch, W.4
-
18
-
-
33646934067
-
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span
-
Lehtinen M.K., Yuan Z., Boag P.R., Yang Y., Villen J., Becker E.B., DiBacco S., de la Iglesia N., Gygi S., Blackwell T.K., et al. A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell 125 (2006) 987-1001
-
(2006)
Cell
, vol.125
, pp. 987-1001
-
-
Lehtinen, M.K.1
Yuan, Z.2
Boag, P.R.3
Yang, Y.4
Villen, J.5
Becker, E.B.6
DiBacco, S.7
de la Iglesia, N.8
Gygi, S.9
Blackwell, T.K.10
-
19
-
-
0035805593
-
Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/Fas-induced apoptosis
-
Graves J.D., Draves K.E., Gotoh Y., Krebs E.G., and Clark E.A. Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/Fas-induced apoptosis. J. Biol. Chem. 276 (2001) 14909-14915
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14909-14915
-
-
Graves, J.D.1
Draves, K.E.2
Gotoh, Y.3
Krebs, E.G.4
Clark, E.A.5
-
20
-
-
0038293152
-
Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase
-
Cheung W.L., Ajiro K., Samejima K., Kloc M., Cheung P., Mizzen C.A., Beeser A., Etkin L.D., Chernoff J., Earnshaw W.C., et al. Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell 113 (2003) 507-517
-
(2003)
Cell
, vol.113
, pp. 507-517
-
-
Cheung, W.L.1
Ajiro, K.2
Samejima, K.3
Kloc, M.4
Cheung, P.5
Mizzen, C.A.6
Beeser, A.7
Etkin, L.D.8
Chernoff, J.9
Earnshaw, W.C.10
-
21
-
-
0037133034
-
Identification of a novel Ras-regulated proapoptotic pathway
-
Khokhlatchev A., Rabizadeh S., Xavier R., Nedwidek M., Chen T., Zhang X.F., Seed B., and Avruch J. Identification of a novel Ras-regulated proapoptotic pathway. Curr. Biol. 12 (2002) 253-265
-
(2002)
Curr. Biol.
, vol.12
, pp. 253-265
-
-
Khokhlatchev, A.1
Rabizadeh, S.2
Xavier, R.3
Nedwidek, M.4
Chen, T.5
Zhang, X.F.6
Seed, B.7
Avruch, J.8
-
22
-
-
33744505111
-
Nore1 and RASSF1 regulation of cell proliferation and of the MST1/2 kinases
-
Avruch J., Praskova M., Ortiz-Vega S., Liu M., and Zhang X.F. Nore1 and RASSF1 regulation of cell proliferation and of the MST1/2 kinases. Methods Enzymol. 407 (2005) 290-310
-
(2005)
Methods Enzymol.
, vol.407
, pp. 290-310
-
-
Avruch, J.1
Praskova, M.2
Ortiz-Vega, S.3
Liu, M.4
Zhang, X.F.5
-
23
-
-
33748664773
-
The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance
-
Emoto K., Parrish J.Z., Jan L.Y., and Jan Y.N. The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance. Nature 443 (2006) 210-213
-
(2006)
Nature
, vol.443
, pp. 210-213
-
-
Emoto, K.1
Parrish, J.Z.2
Jan, L.Y.3
Jan, Y.N.4
-
24
-
-
3242794878
-
Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras
-
Praskova M., Khoklatchev A., Ortiz-Vega S., and Avruch J. Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras. Biochem. J. 381 (2004) 453-462
-
(2004)
Biochem. J.
, vol.381
, pp. 453-462
-
-
Praskova, M.1
Khoklatchev, A.2
Ortiz-Vega, S.3
Avruch, J.4
-
25
-
-
34547162995
-
Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway
-
Hwang E., Ryu K.S., Paakkonen K., Guntert P., Cheong H.K., Lim D.S., Lee J.O., Jeon Y.H., and Cheong C. Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Proc. Natl. Acad. Sci. USA 104 (2007) 9236-9241
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 9236-9241
-
-
Hwang, E.1
Ryu, K.S.2
Paakkonen, K.3
Guntert, P.4
Cheong, H.K.5
Lim, D.S.6
Lee, J.O.7
Jeon, Y.H.8
Cheong, C.9
-
26
-
-
36849052501
-
Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation
-
Rong R., Jiang L.Y., Sheikh M.S., and Huang Y. Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation. Oncogene 26 (2007) 7700-7708
-
(2007)
Oncogene
, vol.26
, pp. 7700-7708
-
-
Rong, R.1
Jiang, L.Y.2
Sheikh, M.S.3
Huang, Y.4
-
27
-
-
43749089372
-
Skp2 regulates the antiproliferative function of the tumor suppressor RASSF1A via ubiquitin-mediated degradation at the G(1)-S transition
-
Song M.S., Song S.J., Kim S.J., Nakayama K., Nakayama K.I., and Lim D.S. Skp2 regulates the antiproliferative function of the tumor suppressor RASSF1A via ubiquitin-mediated degradation at the G(1)-S transition. Oncogene 27 (2007) 3176-3185
-
(2007)
Oncogene
, vol.27
, pp. 3176-3185
-
-
Song, M.S.1
Song, S.J.2
Kim, S.J.3
Nakayama, K.4
Nakayama, K.I.5
Lim, D.S.6
-
28
-
-
24344474135
-
Human NDR kinases are rapidly activated by MOB proteins through recruitment to the plasma membrane and phosphorylation
-
Hergovich A., Bichsel S.J., and Hemmings B.A. Human NDR kinases are rapidly activated by MOB proteins through recruitment to the plasma membrane and phosphorylation. Mol. Cell. Biol. 25 (2005) 8259-8272
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 8259-8272
-
-
Hergovich, A.1
Bichsel, S.J.2
Hemmings, B.A.3
-
29
-
-
34247182696
-
Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila
-
Wei X., Shimizu T., and Lai Z.C. Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila. EMBO J. 26 (2007) 1772-1781
-
(2007)
EMBO J.
, vol.26
, pp. 1772-1781
-
-
Wei, X.1
Shimizu, T.2
Lai, Z.C.3
-
30
-
-
1842557650
-
Initiation of cytokinesis is controlled through multiple modes of regulation of the Sid2p-Mob1p kinase complex
-
Hou M.C., Guertin D.A., and McCollum D. Initiation of cytokinesis is controlled through multiple modes of regulation of the Sid2p-Mob1p kinase complex. Mol. Cell. Biol. 24 (2004) 3262-3276
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 3262-3276
-
-
Hou, M.C.1
Guertin, D.A.2
McCollum, D.3
-
31
-
-
47549115586
-
Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1
-
Hirabayashi S., Nakagawa K., Sumita K., Hidaka S., Kawai T., Ikeda M., Kawata A., Ohno K., and Hata Y. Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1. Oncogene 27 (2008) 4281-4292
-
(2008)
Oncogene
, vol.27
, pp. 4281-4292
-
-
Hirabayashi, S.1
Nakagawa, K.2
Sumita, K.3
Hidaka, S.4
Kawai, T.5
Ikeda, M.6
Kawata, A.7
Ohno, K.8
Hata, Y.9
-
32
-
-
0032907439
-
Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction
-
St John M.A., Tao W., Fei X., Fukumoto R., Carcangiu M.L., Brownstein D.G., Parlow A.F., McGrath J., and Xu T. Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction. Nat. Genet. 21 (1999) 182-186
-
(1999)
Nat. Genet.
, vol.21
, pp. 182-186
-
-
St John, M.A.1
Tao, W.2
Fei, X.3
Fukumoto, R.4
Carcangiu, M.L.5
Brownstein, D.G.6
Parlow, A.F.7
McGrath, J.8
Xu, T.9
-
33
-
-
20844449390
-
Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity
-
McPherson J.P., Tamblyn L., Elia A., Migon E., Shehabeldin A., Matysiak-Zablocki E., Lemmers B., Salmena L., Hakem A., Fish J., et al. Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity. EMBO J. 23 (2004) 3677-3688
-
(2004)
EMBO J.
, vol.23
, pp. 3677-3688
-
-
McPherson, J.P.1
Tamblyn, L.2
Elia, A.3
Migon, E.4
Shehabeldin, A.5
Matysiak-Zablocki, E.6
Lemmers, B.7
Salmena, L.8
Hakem, A.9
Fish, J.10
-
34
-
-
14844297327
-
Control of cell proliferation and apoptosis by mob as tumor suppressor, mats
-
Lai Z.C., Wei X., Shimizu T., Ramos E., Rohrbaugh M., Nikolaidis N., Ho L.L., and Li Y. Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell 120 (2005) 675-685
-
(2005)
Cell
, vol.120
, pp. 675-685
-
-
Lai, Z.C.1
Wei, X.2
Shimizu, T.3
Ramos, E.4
Rohrbaugh, M.5
Nikolaidis, N.6
Ho, L.L.7
Li, Y.8
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