Skp2 regulates the antiproliferative function of the tumor suppressor RASSF1A via ubiquitin-mediated degradation at the G1-S transition

Oncogene

Volumn 27, Issue 22, 2008, Pages 3176-3185

  Song, M S ^a   Song, S J ^a   Kim, S J ^a   Nakayama, K ^b   Nakayama, K I ^c   Lim, D S ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

Cyclin D Cdk4; G1 S transition; RASSF1A; Skp2; Ubiquitination

Indexed keywords

CUL1 PROTEIN; CYCLIN D; CYCLIN DEPENDENT KINASE 4; F BOX PROTEIN; MUTANT PROTEIN; PROTEIN; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; S PHASE KINASE ASSOCIATED PROTEIN 2; SERINE; SKP1 PROTEIN; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE;

AMINO ACID SUBSTITUTION; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; FEMALE; HUMAN; HUMAN CELL; MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; UBIQUITINATION;

ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 4; CYCLINS; G1 PHASE; GENES, TUMOR SUPPRESSOR; HELA CELLS; HUMANS; MICE; NIH 3T3 CELLS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; S PHASE; S-PHASE KINASE-ASSOCIATED PROTEINS; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS; UBIQUITINATION;

EID: 43749089372     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210971     Document Type: Article

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