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Volumn 8, Issue 11, 2013, Pages

Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; CASPASE 3; GENOMIC DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

EID: 84892967171     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079140     Document Type: Article
Times cited : (30)

References (63)
  • 1
    • 77949678340 scopus 로고    scopus 로고
    • Chromatin structure and the inheritance of epigenetic information
    • Margueron R, Reinberg D (2010) Chromatin structure and the inheritance of epigenetic information. Nat Rev Genet 11: 285-296.
    • (2010) Nat Rev Genet , vol.11 , pp. 285-296
    • Margueron, R.1    Reinberg, D.2
  • 2
    • 0032697888 scopus 로고    scopus 로고
    • Mammalian (cytosine-5) methyltransferases cause genomic DNA methylation and lethality in Drosophila
    • Lyko F, Ramsahoye BH, Kashevsky H, Tudor M, Mastrangelo MA, et al. (1999) Mammalian (cytosine-5) methyltransferases cause genomic DNA methylation and lethality in Drosophila. Nat Genet 23: 363-366.
    • (1999) Nat Genet , vol.23 , pp. 363-366
    • Lyko, F.1    Ramsahoye, B.H.2    Kashevsky, H.3    Tudor, M.4    Mastrangelo, M.A.5
  • 3
    • 80052461558 scopus 로고    scopus 로고
    • Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
    • Ito S, Shen L, Dai Q, Wu SC, Collins LB, et al. (2011) Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333: 1300-1303.
    • (2011) Science , vol.333 , pp. 1300-1303
    • Ito, S.1    Shen, L.2    Dai, Q.3    Wu, S.C.4    Collins, L.B.5
  • 4
    • 79959987448 scopus 로고    scopus 로고
    • 5-Hydroxymethylcytosine, the sixth base of the genome
    • Munzel M, Globisch D, Carell T (2011) 5-Hydroxymethylcytosine, the sixth base of the genome. Angew Chem Int Ed Engl 50: 6460-6468.
    • (2011) Angew Chem Int Ed Engl , vol.50 , pp. 6460-6468
    • Munzel, M.1    Globisch, D.2    Carell, T.3
  • 5
    • 42749087226 scopus 로고    scopus 로고
    • Highly integrated single-base resolution maps of the epigenome in Arabidopsis
    • Lister R, O'Malley RC, Tonti-Filippini J, Gregory BD, Berry CC, et al. (2008) Highly integrated single-base resolution maps of the epigenome in Arabidopsis. Cell 133: 523-536.
    • (2008) Cell , vol.133 , pp. 523-536
    • Lister, R.1    O'Malley, R.C.2    Tonti-Filippini, J.3    Gregory, B.D.4    Berry, C.C.5
  • 6
    • 70450217879 scopus 로고    scopus 로고
    • Human DNA methylomes at base resolution show widespread epigenomic differences
    • Lister R, Pelizzola M, Dowen RH, Hawkins RD, Hon G, et al. (2009) Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 462: 315-322.
    • (2009) Nature , vol.462 , pp. 315-322
    • Lister, R.1    Pelizzola, M.2    Dowen, R.H.3    Hawkins, R.D.4    Hon, G.5
  • 7
    • 79956323623 scopus 로고    scopus 로고
    • Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
    • Ficz G, Branco MR, Seisenberger S, Santos F, Krueger F, et al. (2011) Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 473: 398-402.
    • (2011) Nature , vol.473 , pp. 398-402
    • Ficz, G.1    Branco, M.R.2    Seisenberger, S.3    Santos, F.4    Krueger, F.5
  • 8
    • 79952713567 scopus 로고    scopus 로고
    • 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming
    • Wossidlo M, Nakamura T, Lepikhov K, Marques CJ, Zakhartchenko V, et al. (2011) 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming. Nat Commun 2: 241.
    • (2011) Nat Commun , vol.2 , pp. 241
    • Wossidlo, M.1    Nakamura, T.2    Lepikhov, K.3    Marques, C.J.4    Zakhartchenko, V.5
  • 10
    • 84874524531 scopus 로고    scopus 로고
    • Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis
    • Nasonkin IO, Merbs SL, Lazo K, Oliver VF, Brooks M, et al. (2013) Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis. Development 140: 1330-1341.
    • (2013) Development , vol.140 , pp. 1330-1341
    • Nasonkin, I.O.1    Merbs, S.L.2    Lazo, K.3    Oliver, V.F.4    Brooks, M.5
  • 11
    • 84870485051 scopus 로고    scopus 로고
    • Dnmt1-dependent DNA methylation is essential for photoreceptor terminal differentiation and retinal neuron survival
    • Rhee KD, Yu J, Zhao CY, Fan G, Yang XJ (2012) Dnmt1-dependent DNA methylation is essential for photoreceptor terminal differentiation and retinal neuron survival. Cell Death Dis 3: e427.
    • (2012) Cell Death Dis , vol.3
    • Rhee, K.D.1    Yu, J.2    Zhao, C.Y.3    Fan, G.4    Yang, X.J.5
  • 12
    • 0032557817 scopus 로고    scopus 로고
    • Developmental neuronal death is not a universal phenomenon among cell types in the chick embryo retina
    • Cook B, Portera-Cailliau C, Adler R (1998) Developmental neuronal death is not a universal phenomenon among cell types in the chick embryo retina. J Comp Neurol 396: 12-19.
    • (1998) J Comp Neurol , vol.396 , pp. 12-19
    • Cook, B.1    Portera-Cailliau, C.2    Adler, R.3
  • 13
    • 81055125652 scopus 로고    scopus 로고
    • Programmed cell death in animal development and disease
    • Fuchs Y, Steller H (2011) Programmed cell death in animal development and disease. Cell 147: 742-758.
    • (2011) Cell , vol.147 , pp. 742-758
    • Fuchs, Y.1    Steller, H.2
  • 14
    • 73949123842 scopus 로고    scopus 로고
    • Early neural cell death: Numbers and cues from the developing neuroretina
    • Valenciano AI, Boya P, de la Rosa EJ (2009) Early neural cell death: numbers and cues from the developing neuroretina. Int J Dev Biol 53: 1515-1528.
    • (2009) Int J Dev Biol , vol.53 , pp. 1515-1528
    • Valenciano, A.I.1    Boya, P.2    De La Rosa, E.J.3
  • 15
    • 0242539759 scopus 로고    scopus 로고
    • Generation of retinal ganglion cells is modulated by caspase-dependent programmed cell death
    • Mayordomo R, Valenciano AI, de la Rosa EJ, Hallbook F (2003) Generation of retinal ganglion cells is modulated by caspase-dependent programmed cell death. Eur J Neurosci 18: 1744-1750.
    • (2003) Eur J Neurosci , vol.18 , pp. 1744-1750
    • Mayordomo, R.1    Valenciano, A.I.2    De La Rosa, E.J.3    Hallbook, F.4
  • 16
    • 0016232976 scopus 로고
    • C57BL-6J mice with inherited retinal degeneration
    • LaVail MM, Sidman RL (1974) C57BL-6J mice with inherited retinal degeneration. Arch Ophthalmol 91: 394-400.
    • (1974) Arch Ophthalmol , vol.91 , pp. 394-400
    • LaVail, M.M.1    Sidman, R.L.2
  • 18
    • 0037707639 scopus 로고    scopus 로고
    • Caspase-independent photoreceptor apoptosis in mouse models of retinal degeneration
    • Doonan F, Donovan M, Cotter TG (2003) Caspase-independent photoreceptor apoptosis in mouse models of retinal degeneration. J Neurosci 23: 5723-5731.
    • (2003) J Neurosci , vol.23 , pp. 5723-5731
    • Doonan, F.1    Donovan, M.2    Cotter, T.G.3
  • 19
    • 1542427168 scopus 로고    scopus 로고
    • Caspase-3 in postnatal retinal development and degeneration
    • Zeiss CJ, Neal J, Johnson EA (2004) Caspase-3 in postnatal retinal development and degeneration. Invest Ophthalmol Vis Sci 45: 964-970.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 964-970
    • Zeiss, C.J.1    Neal, J.2    Johnson, E.A.3
  • 21
    • 0036020418 scopus 로고    scopus 로고
    • Activation of caspase-3 during degeneration of the outer nuclear layer in the rd mouse retina
    • Kim DH, Kim JA, Choi JS, Joo CK (2002) Activation of caspase-3 during degeneration of the outer nuclear layer in the rd mouse retina. Ophthalmic Res 34: 150-157.
    • (2002) Ophthalmic Res , vol.34 , pp. 150-157
    • Kim, D.H.1    Kim, J.A.2    Choi, J.S.3    Joo, C.K.4
  • 22
    • 0036946626 scopus 로고    scopus 로고
    • Caspase-3 inhibitor transiently delays inherited retinal degeneration in C3H mice carrying the rd gene
    • Yoshizawa K, Kiuchi K, Nambu H, Yang J, Senzaki H, et al. (2002) Caspase-3 inhibitor transiently delays inherited retinal degeneration in C3H mice carrying the rd gene. Graefes Arch Clin Exp Ophthalmol 240: 214-219.
    • (2002) Graefes Arch Clin Exp Ophthalmol , vol.240 , pp. 214-219
    • Yoshizawa, K.1    Kiuchi, K.2    Nambu, H.3    Yang, J.4    Senzaki, H.5
  • 23
    • 2942678703 scopus 로고    scopus 로고
    • Knock-in human rhodopsin-GFP fusions as mouse models for human disease and targets for gene therapy
    • Chan F, Bradley A, Wensel TG, Wilson JH (2004) Knock-in human rhodopsin-GFP fusions as mouse models for human disease and targets for gene therapy. Proc Natl Acad Sci U S A 101: 9109-9114.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 9109-9114
    • Chan, F.1    Bradley, A.2    Wensel, T.G.3    Wilson, J.H.4
  • 24
    • 33750633662 scopus 로고    scopus 로고
    • Defective development of photoreceptor membranes in a mouse model of recessive retinal degeneration
    • Gross AK, Decker G, Chan F, Sandoval IM, Wilson JH, et al. (2006) Defective development of photoreceptor membranes in a mouse model of recessive retinal degeneration. Vision Res 46: 4510-4518.
    • (2006) Vision Res , vol.46 , pp. 4510-4518
    • Gross, A.K.1    Decker, G.2    Chan, F.3    Sandoval, I.M.4    Wilson, J.H.5
  • 25
    • 0027018236 scopus 로고
    • A series of normal stages in the development of the chick embryo
    • Hamburger V, Hamilton HL (1992) A series of normal stages in the development of the chick embryo. 1951. Dev Dyn 195: 231-272.
    • (1951) Dev Dyn , vol.195 , pp. 231-272
    • Hamburger, V.1    Hamilton, H.L.2
  • 26
    • 0025039744 scopus 로고
    • Improved method for obtaining 3-microns cryosections for immunocytochemistry
    • Barthel LK, Raymond PA (1990) Improved method for obtaining 3-microns cryosections for immunocytochemistry. J Histochem Cytochem 38: 1383-1388.
    • (1990) J Histochem Cytochem , vol.38 , pp. 1383-1388
    • Barthel, L.K.1    Raymond, P.A.2
  • 27
    • 38549169010 scopus 로고    scopus 로고
    • Molecular dynamics of photoreceptor synapse formation in the developing chick retina
    • Wahlin KJ, Moreira EF, Huang H, Yu N, Adler R (2008) Molecular dynamics of photoreceptor synapse formation in the developing chick retina. J Comp Neurol 506: 822-837.
    • (2008) J Comp Neurol , vol.506 , pp. 822-837
    • Wahlin, K.J.1    Moreira, E.F.2    Huang, H.3    Yu, N.4    Adler, R.5
  • 28
    • 0042837950 scopus 로고    scopus 로고
    • Ischemic preconditioning by caspase cleavage of poly(ADP-ribose) polymerase-1
    • Garnier P, Ying W, Swanson RA (2003) Ischemic preconditioning by caspase cleavage of poly(ADP-ribose) polymerase-1. J Neurosci 23: 7967-7973.
    • (2003) J Neurosci , vol.23 , pp. 7967-7973
    • Garnier, P.1    Ying, W.2    Swanson, R.A.3
  • 29
    • 77951209245 scopus 로고    scopus 로고
    • BDNF is required for the survival of differentiated geniculate ganglion neurons
    • Patel AV, Krimm RF (2010) BDNF is required for the survival of differentiated geniculate ganglion neurons. Dev Biol 340: 419-429.
    • (2010) Dev Biol , vol.340 , pp. 419-429
    • Patel, A.V.1    Krimm, R.F.2
  • 30
    • 84875122023 scopus 로고    scopus 로고
    • Heterogenic final cell cycle by chicken retinal Lim1 horizontal progenitor cells leads to heteroploid cells with a remaining replicated genome
    • Shirazi Fard S, Jarrin M, Boije H, Fillon V, All-Eriksson C, et al. (2013) Heterogenic final cell cycle by chicken retinal Lim1 horizontal progenitor cells leads to heteroploid cells with a remaining replicated genome. PLoS One 8: e59133.
    • (2013) PLoS One , vol.8
    • Shirazi Fard, S.1    Jarrin, M.2    Boije, H.3    Fillon, V.4    All-Eriksson, C.5
  • 31
    • 84861762712 scopus 로고    scopus 로고
    • Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy
    • McIntyre A, Patiar S, Wigfield S, Li JL, Ledaki I, et al. (2012) Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy. Clin Cancer Res 18: 3100-3111.
    • (2012) Clin Cancer Res , vol.18 , pp. 3100-3111
    • McIntyre, A.1    Patiar, S.2    Wigfield, S.3    Li, J.L.4    Ledaki, I.5
  • 32
    • 77949898210 scopus 로고    scopus 로고
    • ALK1 signaling regulates early postnatal lymphatic vessel development
    • Niessen K, Zhang G, Ridgway JB, Chen H, Yan M (2010) ALK1 signaling regulates early postnatal lymphatic vessel development. Blood 115: 1654-1661.
    • (2010) Blood , vol.115 , pp. 1654-1661
    • Niessen, K.1    Zhang, G.2    Ridgway, J.B.3    Chen, H.4    Yan, M.5
  • 33
    • 0037175338 scopus 로고    scopus 로고
    • Ultrastructure of retinal ganglion cell death after axotomy in chick embryos
    • Borsello T, Mottier V, Castagne V, Clarke PG (2002) Ultrastructure of retinal ganglion cell death after axotomy in chick embryos. J Comp Neurol 453: 361-371.
    • (2002) J Comp Neurol , vol.453 , pp. 361-371
    • Borsello, T.1    Mottier, V.2    Castagne, V.3    Clarke, P.G.4
  • 34
    • 79960192809 scopus 로고    scopus 로고
    • Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats
    • Kaur J, Mencl S, Sahaboglu A, Farinelli P, van Veen T, et al. (2011) Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats. PLoS One 6: e22181.
    • (2011) PLoS One , vol.6
    • Kaur, J.1    Mencl, S.2    Sahaboglu, A.3    Farinelli, P.4    Van Veen, T.5
  • 35
    • 34548847441 scopus 로고    scopus 로고
    • Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse
    • Paquet-Durand F, Silva J, Talukdar T, Johnson LE, Azadi S, et al. (2007) Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse. J Neurosci 27: 10311-10319.
    • (2007) J Neurosci , vol.27 , pp. 10311-10319
    • Paquet-Durand, F.1    Silva, J.2    Talukdar, T.3    Johnson, L.E.4    Azadi, S.5
  • 36
    • 0021774471 scopus 로고
    • Monoclonal antibodies to poly(adenosine diphosphate ribose) recognize different structures
    • Kawamitsu H, Hoshino H, Okada H, Miwa M, Momoi H, et al. (1984) Monoclonal antibodies to poly(adenosine diphosphate ribose) recognize different structures. Biochemistry 23: 3771-3777.
    • (1984) Biochemistry , vol.23 , pp. 3771-3777
    • Kawamitsu, H.1    Hoshino, H.2    Okada, H.3    Miwa, M.4    Momoi, H.5
  • 37
    • 58149263490 scopus 로고    scopus 로고
    • Preclinical modeling of a phase 0 clinical trial: Qualification of a pharmacodynamic assay of poly (ADP-ribose) polymerase in tumor biopsies of mouse xenografts
    • Kinders RJ, Hollingshead M, Khin S, Rubinstein L, Tomaszewski JE, et al. (2008) Preclinical modeling of a phase 0 clinical trial: qualification of a pharmacodynamic assay of poly (ADP-ribose) polymerase in tumor biopsies of mouse xenografts. Clin Cancer Res 14: 6877-6885.
    • (2008) Clin Cancer Res , vol.14 , pp. 6877-6885
    • Kinders, R.J.1    Hollingshead, M.2    Khin, S.3    Rubinstein, L.4    Tomaszewski, J.E.5
  • 38
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119: 493-501.
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 39
    • 35848962965 scopus 로고    scopus 로고
    • Differential, age-dependent MEK-ERK and PI3K-Akt activation by insulin acting as a survival factor during embryonic retinal development
    • Chavarria T, Valenciano AI, Mayordomo R, Egea J, Comella JX, et al. (2007) Differential, age-dependent MEK-ERK and PI3K-Akt activation by insulin acting as a survival factor during embryonic retinal development. Dev Neurobiol 67: 1777-1788.
    • (2007) Dev Neurobiol , vol.67 , pp. 1777-1788
    • Chavarria, T.1    Valenciano, A.I.2    Mayordomo, R.3    Egea, J.4    Comella, J.X.5
  • 41
    • 84873729483 scopus 로고    scopus 로고
    • Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins
    • Zencak D, Schouwey K, Chen D, Ekstrom P, Tanger E, et al. (2013) Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins. Proc Natl Acad Sci U S A 110: E593-601.
    • (2013) Proc Natl Acad Sci U S A , vol.110
    • Zencak, D.1    Schouwey, K.2    Chen, D.3    Ekstrom, P.4    Tanger, E.5
  • 42
    • 33847702500 scopus 로고    scopus 로고
    • Cellular responses to photoreceptor death in the rd1 mouse model of retinal degeneration
    • Punzo C, Cepko C (2007) Cellular responses to photoreceptor death in the rd1 mouse model of retinal degeneration. Invest Ophthalmol Vis Sci 48: 849-857.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 849-857
    • Punzo, C.1    Cepko, C.2
  • 43
    • 64249124468 scopus 로고    scopus 로고
    • The nucleus inside out-through a rod darkly
    • Ragoczy T, Groudine M (2009) The nucleus inside out-through a rod darkly. Cell 137: 205-207.
    • (2009) Cell , vol.137 , pp. 205-207
    • Ragoczy, T.1    Groudine, M.2
  • 44
    • 0029294613 scopus 로고
    • In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note
    • Grasl-Kraupp B, Ruttkay-Nedecky B, Koudelka H, Bukowska K, Bursch W, et al. (1995) In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note. Hepatology 21: 1465-1468.
    • (1995) Hepatology , vol.21 , pp. 1465-1468
    • Grasl-Kraupp, B.1    Ruttkay-Nedecky, B.2    Koudelka, H.3    Bukowska, K.4    Bursch, W.5
  • 45
    • 0035962631 scopus 로고    scopus 로고
    • DNA methylation, methyltransferases, and cancer
    • Robertson KD (2001) DNA methylation, methyltransferases, and cancer. Oncogene 20: 3139-3155.
    • (2001) Oncogene , vol.20 , pp. 3139-3155
    • Robertson, K.D.1
  • 46
    • 0027521914 scopus 로고
    • Apoptosis: Final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice
    • Chang GQ, Hao Y, Wong F (1993) Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice. Neuron 11: 595-605.
    • (1993) Neuron , vol.11 , pp. 595-605
    • Chang, G.Q.1    Hao, Y.2    Wong, F.3
  • 47
  • 49
    • 84255210700 scopus 로고    scopus 로고
    • Molecular definitions of cell death subroutines: Recommendations of the Nomenclature Committee on Cell Death 2012
    • Galluzzi L, Vitale I, Abrams JM, Alnemri ES, Baehrecke EH, et al. (2012) Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ 19: 107-120.
    • (2012) Cell Death Differ , vol.19 , pp. 107-120
    • Galluzzi, L.1    Vitale, I.2    Abrams, J.M.3    Alnemri, E.S.4    Baehrecke, E.H.5
  • 50
    • 33751239138 scopus 로고    scopus 로고
    • Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors
    • Sanges D, Comitato A, Tammaro R, Marigo V (2006) Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors. Proc Natl Acad Sci U S A 103: 17366-17371.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 17366-17371
    • Sanges, D.1    Comitato, A.2    Tammaro, R.3    Marigo, V.4
  • 51
    • 38449086823 scopus 로고    scopus 로고
    • Activation of endoplasmic reticulum stress in degenerating photoreceptors of the rd1 mouse
    • Yang LP, Wu LM, Guo XJ, Tso MO (2007) Activation of endoplasmic reticulum stress in degenerating photoreceptors of the rd1 mouse. Invest Ophthalmol Vis Sci 48: 5191-5198.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 5191-5198
    • Yang, L.P.1    Wu, L.M.2    Guo, X.J.3    Tso, M.O.4
  • 52
    • 79953840957 scopus 로고    scopus 로고
    • Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos)
    • Wang Y, Kim NS, Haince JF, Kang HC, David KK, et al. (2011) Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos). Sci Signal 4: ra20.
    • (2011) Sci Signal , vol.4
    • Wang, Y.1    Kim, N.S.2    Haince, J.F.3    Kang, H.C.4    David, K.K.5
  • 53
    • 78649510331 scopus 로고    scopus 로고
    • PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function
    • Sahaboglu A, Tanimoto N, Kaur J, Sancho-Pelluz J, Huber G, et al. (2010) PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function. PLoS One 5: e15495.
    • (2010) PLoS One , vol.5
    • Sahaboglu, A.1    Tanimoto, N.2    Kaur, J.3    Sancho-Pelluz, J.4    Huber, G.5
  • 54
    • 81255143014 scopus 로고    scopus 로고
    • Epigenetic regulation of motor neuron cell death through DNA methylation
    • Chestnut BA, Chang Q, Price A, Lesuisse C, Wong M, et al. (2011) Epigenetic regulation of motor neuron cell death through DNA methylation. J Neurosci 31: 16619-16636.
    • (2011) J Neurosci , vol.31 , pp. 16619-16636
    • Chestnut, B.A.1    Chang, Q.2    Price, A.3    Lesuisse, C.4    Wong, M.5
  • 55
    • 84857111200 scopus 로고    scopus 로고
    • DNase I sensitivity QTLs are a major determinant of human expression variation
    • Degner JF, Pai AA, Pique-Regi R, Veyrieras JB, Gaffney DJ, et al. (2012) DNase I sensitivity QTLs are a major determinant of human expression variation. Nature 482: 390-394.
    • (2012) Nature , vol.482 , pp. 390-394
    • Degner, J.F.1    Pai, A.A.2    Pique-Regi, R.3    Veyrieras, J.B.4    Gaffney, D.J.5
  • 56
    • 33749179804 scopus 로고    scopus 로고
    • Zebra fish Dnmt1 and Suv39h1 regulate organ-specific terminal differentiation during development
    • Rai K, Nadauld LD, Chidester S, Manos EJ, James SR, et al. (2006) Zebra fish Dnmt1 and Suv39h1 regulate organ-specific terminal differentiation during development. Mol Cell Biol 26: 7077-7085.
    • (2006) Mol Cell Biol , vol.26 , pp. 7077-7085
    • Rai, K.1    Nadauld, L.D.2    Chidester, S.3    Manos, E.J.4    James, S.R.5
  • 57
    • 78651491413 scopus 로고    scopus 로고
    • A role for DNA methylation in regulation of EphA5 receptor expression in the mouse retina
    • Petkova TD, Seigel GM, Otteson DC (2011) A role for DNA methylation in regulation of EphA5 receptor expression in the mouse retina. Vision Res 51: 260-268.
    • (2011) Vision Res , vol.51 , pp. 260-268
    • Petkova, T.D.1    Seigel, G.M.2    Otteson, D.C.3
  • 58
    • 78650826181 scopus 로고    scopus 로고
    • Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates
    • Globisch D, Munzel M, Muller M, Michalakis S, Wagner M, et al. (2010) Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates. PLoS ONE 5: e15367.
    • (2010) PLoS ONE , vol.5
    • Globisch, D.1    Munzel, M.2    Muller, M.3    Michalakis, S.4    Wagner, M.5
  • 59
    • 66149123748 scopus 로고    scopus 로고
    • The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
    • Kriaucionis S, Heintz N (2009) The nuclear DNA base 5- hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324: 929-930.
    • (2009) Science , vol.324 , pp. 929-930
    • Kriaucionis, S.1    Heintz, N.2
  • 61
    • 77952656234 scopus 로고    scopus 로고
    • Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis
    • Pelzel HR, Schlamp CL, Nickells RW (2010) Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis. BMC Neurosci 11: 62.
    • (2010) BMC Neurosci , vol.11 , pp. 62
    • Pelzel, H.R.1    Schlamp, C.L.2    Nickells, R.W.3
  • 62
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
    • Cameron EE, Bachman KE, Myohanen S, Herman JG, Baylin SB (1999) Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet 21: 103-107.
    • (1999) Nat Genet , vol.21 , pp. 103-107
    • Cameron, E.E.1    Bachman, K.E.2    Myohanen, S.3    Herman, J.G.4    Baylin, S.B.5
  • 63
    • 0037276902 scopus 로고    scopus 로고
    • The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells
    • Zhu WG, Otterson GA (2003) The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells. Curr Med Chem Anticancer Agents 3: 187-199.
    • (2003) Curr Med Chem Anticancer Agents , vol.3 , pp. 187-199
    • Zhu, W.G.1    Otterson, G.A.2


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