PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Sahaboglu, Ayse ^a   Tanimoto, Naoyuki ^b   Kaur, Jasvir ^a   Sancho Pelluz, Javier ^a,d   Huber, Gesine ^b   Fahl, Edda ^b   Arango Gonzalez, Blanca ^a   Zrenner, Eberhart ^a   Ekström, Per ^c   Löwenheim, Hubert ^a   Seeliger, Mathias ^b   Paquet Durand, François ^a,d  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c LUND UNIVERSITY   (Sweden)

^d New York Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PHOSPHODIESTERASE VI; CYCLIC GMP; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, MOUSE; PHOSPHODIESTERASE INHIBITOR; PURINE DERIVATIVE; ZAPRINAST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DEATH; DISEASE RESISTANCE; ELECTRORETINOGRAPHY; ENZYME ACTIVITY; ENZYME INHIBITION; EX VIVO STUDY; EXPLANT; GENE INACTIVATION; GENOTYPE; HISTOLOGY; IN VIVO STUDY; LOSS OF FUNCTION MUTATION; MORPHOLOGY; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; PHOTORECEPTOR; RETINA; RETINA DEGENERATION; RETINITIS PIGMENTOSA; 129 MOUSE; ANIMAL; APOPTOSIS; C3H MOUSE; DRUG ANTAGONISM; ENZYMOLOGY; FEMALE; GENETICS; HUMAN; MALE; METABOLISM; MOUSE; MOUSE MUTANT; NICK END LABELING; PATHOLOGY; PATHOPHYSIOLOGY; PHOTORECEPTOR CELL; WESTERN BLOTTING;

ANIMALIA; MUS;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CYCLIC GMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 6; ELECTRORETINOGRAPHY; FEMALE; HUMANS; IN SITU NICK-END LABELING; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C3H; MICE, KNOCKOUT; PHOSPHODIESTERASE INHIBITORS; PHOTORECEPTOR CELLS, VERTEBRATE; POLY(ADP-RIBOSE) POLYMERASES; PURINONES; RETINA; RETINAL DEGENERATION; RETINITIS PIGMENTOSA; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 78649510331     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015495     Document Type: Article

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