Local administration of alendronate reduced peri-tunnel bone loss and promoted graft-bone tunnel healing with minimal systemic effect on bone in contralateral knee

Journal of Orthopaedic Research

Volumn 31, Issue 12, 2013, Pages 1897-1906

  Lui, Pauline Po Yee ^a   Lee, Yuk Wa ^b   Mok, Tsui Yu ^b   Cheuk, Yau Chuk ^b  

^a HOSPITAL AUTHORITY   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

alendronate; anterior cruciate ligament reconstruction; bisphosphonate; peri tunnel bone loss; tendon graft to bone tunnel healing

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; METHACRYLIC ACID METHYL ESTER; POLYETHYLENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTERIOR CRUCIATE LIGAMENT INJURY; ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION; ARTICLE; BINDING AFFINITY; BIOMECHANICS; BONE; BONE DENSITY; BONE MINERAL; BONE STRENGTH; BONE TUNNEL; COMPUTED TOMOGRAPHY SCANNER; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFECT; EPIPHYSIS; FEMUR; HEALING; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HISTOLOGY; KNEE; LOADING TEST; LOW DRUG DOSE; MACHINE; MATERIALS TESTING; METAPHYSIS; NONHUMAN; OSTEOLYSIS; PERI TUNNEL BONE LOSS; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RAT; TENDON GRAFT; TENDON GRAFT TO BONE TUNNEL HEALING; TENSILE STRENGTH; TIBIA;

EID: 84886296304     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22442     Document Type: Article

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